Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线粒体乙醛脱氢酶是体内催化硝酸甘油生物转化的主要途径，线粒体乙醛脱氢酶同时具有脱氢酶和酯酶的催化活性，其酯酶活性可以通过将硝酸甘油脱硝形成一氧化氮，进而血管扩张。