Amyloid plaque seems to be kind of choking the neurons ability to utilize glucose.

淀粉样斑块似乎抑制了神经元利用葡萄糖的能力。

Look at the texture -- the amyloid plaques.

太恶心了。

It, too, targets amyloid plaques in the brain.

它针对的也是大脑中的淀粉样斑。

Amyloid plaque is a protein commonly found in the brains of people with Alzheimer's.

淀粉样斑块是阿尔茨海默病患者大脑中常见的一种蛋白质。

Protein levels also closely corresponded with the severity of amyloid plaques and tau tangles in brain tissue from people who had died with Alzheimer's.

脑源性 Tau 蛋白质水平还与阿尔茨海默病患者脑组织中的淀粉样斑块和 Tau 蛋白缠结的严重程度密切相关。

Think of amyloid plaques as a lit match.

将淀粉样斑块想象成一根点燃的火柴。

I want to be able to image amyloid plaque.

我希望能够对淀粉样斑块进行成像。

So what happens when amyloid plaques accumulate to this tipping point?

那么当淀粉样斑块积累到这个临界点时会发生什么呢？

So what are the things that influence those amyloid plaque levels?

那么影响这些淀粉样蛋白斑块水平的因素是什么？

" What is it that degrades the amyloid plaque, what clears it out — you were saying that's one of the issues, it's not getting cleared out."

“什么东西能降解或者清除淀粉样斑块——您刚才说这是问题之一，淀粉样斑块无法排出或清除掉。”

A calorie-controlled diet also protected neurons against the build-up of amyloid plaques.

控制卡路里的饮食还可以保护神经元免受淀粉样蛋白斑块的形成。

Let's imagine that your amyloid plaques have reached that tipping point.

让我们想象一下， 您的淀粉样斑块已经达到了临界点。

Research has found that hemoglobin and heme itself help reduce inflammation in the brain and clear out the problematic amyloid plaques found in the brain of Alzheimer's patients.

研究发现，血红蛋白和血红素本身有助于减少大脑中的炎症，清除阿尔茨海默病患者大脑中存在的有问题的淀粉样蛋白斑块。

The study used brain scans and samples of spinal fluid to look at the biological hallmarks of Alzheimer's, amyloid plaques and tangles made up of proteins called tau.

这项研究利用脑部扫描和脊髓液样本来观察阿尔茨海默氏症的生物学特征、淀粉样斑块和由tau蛋白构成的缠结。

This accumulation of amyloid plaques takes 15 to 20 years, and can be influenced by how we live.

淀粉样斑块的积累需要 15 至 20 年的时间，并且可能受到我们生活方式的影响。

If you remember, I mentioned that estrogen declines could potentially promote the formation of amyloid plaques, or Alzheimer's plaques.

如果你还记得的话，我提到过雌激素下降可能会促进淀粉样斑块或阿尔茨海默病斑块的形成。

Let's say your amyloid plaque levels have reached that tipping point, and it's triggered the cascade that causes Alzheimer's.

假设您的淀粉样蛋白斑水平已达到临界点，它引发了导致阿尔茨海默病的级联反应。

In Alzheimer's disease, beta-amyloid clumps together to form amyloid plaques, which are thought to induce neuroinflammation and disrupt communication between neurons.

在阿尔茨海默病中，β-淀粉样蛋白聚集在一起形成淀粉样斑块，这被认为是诱发神经炎症和破坏神经元之间的通讯。

If this happens over decades, right, 15 to 20 years of amyloid plaque accumulation, you are increasing your risk of developing Alzheimer's.

如果淀粉样蛋白斑块的积累持续数十年（正确的15至20年），那么您患阿尔茨海默病的风险就会增加。

And studies have shown that this process can even lead to the formation of amyloid plaques, or Alzheimer's plaques, which are a hallmark of Alzheimer's disease.

研究表明，这个过程甚至会导致淀粉样斑块或阿尔茨海默病斑块的形成，这是阿尔茨海默病的标志。