The substance concerned, TDI-11861, belongs to a class of molecules called soluble adenylyl cyclase (sAC) inhibitors.

这种名为TDI-11861的物质属于可溶性腺苷酸环化酶(sAC)抑制剂。

The nitric oxide diffuses into the nearby smooth muscle cells, and activates guanylate cyclase, which converts GTP molecules to cGMP.

一氧化氮扩散到附近的平滑肌细胞，激活鸟苷酸环化酶，将GTP分子转化为cGMP。

So, this causes the G-protein to becomes permanently activated and it keeps activating a membrane-bound protein called adenylate cyclase.

因此，这导致G蛋白被永久激活，并继续激活称为腺苷酸环化酶的膜结合蛋白。

The G protein activates adenylate cyclase, the enzyme that catalyzes the production of cAMP from ATP.

G蛋白激活腺苷酸环化酶，该酶催化ATP生成cAMP。