| 单词 | translational |
| 例句 | Last month, she received a Ph.D. in genetics and genomics from Harvard, along with a certificate in human biology and translational medicine. Samantha Schilit, Jeremy Rosenweig 2019-04-14T04:00:00Z "Many people equate taking medication with getting better," says Paul Doering, professor in the department of pharmacotherapy and translational research at the University of Florida College of Pharmacy. The Most Medicated States 2010-08-16T16:15:00Z The plot chronicles the translational and trans-national tensions that develop when the owner of an American sign company travels to China in hopes of stirring up business there. ArtsBeat: By Way of Chicago, David Henry Hwang Comedy 'Chinglish' Will Come to Broadway 2011-06-28T19:00:05Z All this sounds familiar to Roz Shafran, the co-author of Overcoming Perfectionism and the chair in translational psychology at University College London’s Institute of Child Health. ‘My brain feels like it’s been punched’: the intolerable rise of perfectionism 2018-07-17T04:00:00Z She also received a doctoral degree in dental medicine and a master’s degree in translational research from Penn. Nishat Shahabuddin, Shawn Shafiei 2019-09-22T04:00:00Z Kenneth S. Campbell, Ph.D., the director of translational research in the Division of Cardiovascular Medicine in the UK College of Medicine, helped map out an important part of the heart on a molecular level. Researcher helps solve 60-year mystery inside heart 2023-11-14T05:00:00Z "One of the things that drew us to come here to start our research groups is that human translational research at the University of Colorado School of Medicine is so strong," Jonsson says. Toward new targeted treatments for rheumatoid arthritis 2023-11-08T05:00:00Z These latest translational results represent more than a decade of research. Repurposed drug offers new potential for managing type 1 diabetes 2023-11-01T04:00:00Z The work was supported by Clinical and translational award for infrastructure UL1TR004419. What is the impact of predictive AI in the health care setting? 2023-10-09T04:00:00Z “Our idea is to take our funding, put it into these translational science, kind of in this valley of death where you’ve got good ideas, but they’re very risky,” he said. Lauder family pledges $200M to its Alzheimer’s research work 2023-04-04T04:00:00Z An aperiodic tiling displays no such “translational symmetry,” and mathematicians have long sought a single shape that could tile the plane in such a fashion. Elusive ‘Einstein’ Solves a Longstanding Math Problem 2023-03-28T04:00:00Z Similarly, "I felt like this would be the most fertile ground for us to continue our computational-experimental productive pattern for translational medicine," Zhang says. Toward new targeted treatments for rheumatoid arthritis 2023-11-08T05:00:00Z Back then, the organizers of the second summit concluded that “it is time to define a rigorous, responsible translational pathway” toward clinical trials of germline editing. Gene-editing summit touts sickle cell success, while questions on embryo editing linger 2023-03-12T05:00:00Z These quantities are analogous to the translational quantities x, v , and a . College Physics for AP Courses 2015-08-12T00:00:00Z Differences in the amino acids cause post- translational modification of the protein, which reassembles to produce a functional protein. Biology for AP Courses 2022-06-09T00:00:00Z Dr Aimee Grant of Swansea University's centre for lactation, infant feeding and translational research led the study which looked at existing research mostly from the UK, USA and Australia. Breastfeeding: Mums put off by public disgust - study 2022-08-02T04:00:00Z “The authors really nailed it here,” said Dr. Ross Levine, the deputy physician in chief for translational research at Memorial Sloan Kettering Cancer Center. As Y Chromosomes Vanish With Age, Heart Risks May Grow 2022-07-14T04:00:00Z The important types of mass wasting are creep, slump, translational slide, rotational slide, fall, and debris flow or mudflow. Physical Geology 2015-01-01T00:00:00Z It is also precisely analogous in form to its translational counterpart. College Physics for AP Courses 2015-08-12T00:00:00Z Rotational and translational landslides often have extensional cracks, sag ponds, hummocky terrain, and pressure ridges. An Introduction to Geology 2017-01-01T00:00:00Z “Are we responsible for inferences patients will make about the translational likelihood of this research?” she asks. Brain surgeries are opening windows for neuroscientists, but ethical questions abound 2022-01-18T05:00:00Z Once the center has hired more faculty and staff — Pravetoni is currently its sole faculty member — and has the capacity to run clinical trials, he envisions it as a translational research hub. To fight opioid crisis, UW researchers take new shot at developing vaccine against addictive drugs 2022-01-05T05:00:00Z The money will back education and research efforts in applied microeconomics, business, digital medicine, global health, neuroscience, and translational research programs at the university’s Feinberg School of Medicine. $15B from Gates, French Gates tops 2021 biggest gift list 2021-12-31T05:00:00Z It wins because it converts its entire PE into translational KE. College Physics for AP Courses 2015-08-12T00:00:00Z “I think that the next frontier is to really make this more translational.” Nanotechnology Offers New Ways to Fight an Endless Pandemic 2021-10-15T04:00:00Z “Ginkgo wouldn’t exist today without translational research capital from the government,” Mr. Kelly said. Biology Starts to Get a Technological Makeover 2021-09-16T04:00:00Z Until the current study, “There was no proof that you could take an animal, improve translational fidelity, and make it live longer,” Gorbunova says. Antiaging advice from single-celled creatures: Build better proteins 2021-09-14T04:00:00Z Vaccines are in fact the final, translational part of product development that is years in the making and involves enormous upstream investment. Who owns COVID-19 vaccines? 2021-08-08T04:00:00Z It comes in third because the soup rotates along with the can, taking even more of the initial PE for rotational KE, leaving less for translational KE. College Physics for AP Courses 2015-08-12T00:00:00Z The director of the office of translational sciences, Dr. ShaAvhrée Buckman-Garner — who supervises both the pharmacology and biostatistics offices — did not vote yes or no, saying she understood both arguments. How an unproven Alzheimer’s drug got approved 2021-07-20T04:00:00Z Indeed, research from translational neuroscience explains why the centuries old scam of catfishing continues to flourish despite increased media attention. How catfishers exploit basic human neuroscience 2021-05-31T04:00:00Z “These are translational data that suggests the placenta doesn’t see any injurious impact of the vaccine. And that’s really fantastic.” Coronavirus Vaccines Protect Pregnant Women, Another Study Suggests 2021-05-13T04:00:00Z It will be used to found the Dr. Glenn R. and Nancy A. Linnerson Imaging Center to advance comparative and translational medicine research at the university. Missouri’s veterinary college receives $11 million gift 2021-03-09T05:00:00Z By now the pattern is clear—every rotational phenomenon has a direct translational analog. College Physics for AP Courses 2015-08-12T00:00:00Z In principle, using equity and justice as a factor in vaccine distribution is laudable, said Dr. Michael DeBaun, vice chair for clinical and translational research at Vanderbilt. Will the Hardest-Hit Communities Get the Coronavirus Vaccine? 2020-10-30T04:00:00Z “We want to determine the dosing regimen that produces the fastest recovery and the least toxicity for the patient,” said Jürgen Bulitta, Ph.D., a professor of pharmacotherapy and translational research in the College of Pharmacy. Trio of antiviral drugs eyed as possible coronavirus treatment 2020-09-09T04:00:00Z The institute’s translational team works with researchers one-on-one to develop the project, support its growth and secure the next round of funding. The four pillars of a successful science spin-off company 2020-07-12T04:00:00Z Most of the work was basic science or early translational science, meaning it did not involve clinical trials. More than 50 scientists fired or resign after NIH probe into grants’ foreign support 2020-06-17T04:00:00Z The kinetic energy before the collision is the incoming disk's translational kinetic energy, and after the collision, it is the rotational kinetic energy of the two stuck together. College Physics for AP Courses 2015-08-12T00:00:00Z The business sector accounts for some 70% of spending on basic, applied and translational research. Sputnik moment or budget breaker: How will the pandemic alter research funding? 2020-06-01T04:00:00Z Mitra Ahadpour, a 55-year-old who lives in Potomac, is a physician and principal deputy director of translational sciences at the Food and Drug Administration. This Montgomery County school board race has more candidates, and more conflict, than usual 2020-05-30T04:00:00Z Considering that BFD1 is probably regulated by translational control, approaches that determine the RNA content of single cells might not be enough to identify the full cohort of factors driving differentiation. One gene to rule them all in a chronic brain infection 2020-03-01T05:00:00Z Beyond these key impacts on translational research, the paper raised questions about how developmental origin affects the maintenance of cell identity. A decade of questions about the fluidity of cell identity 2020-02-23T05:00:00Z Work and energy in rotational motion are completely analogous to work and energy in translational motion. College Physics for AP Courses 2015-08-12T00:00:00Z All this translational work on communication, decision-making, psychology and behaviour requires serious attention and proper funding. There could soon be a test to detect cancer years in advance. Would you take it? | Saskia Sanderson 2020-02-14T05:00:00Z Royal Society established a commission to develop a framework for a “translational pathway” for editing human embryos in order to produce genetically engineered children. Should We Alter the Human Genome? Let Democracy Decide 2020-01-15T05:00:00Z Another way to investigate translational control is to profile RNAs bound to the translational machinery of the ribosome complex. One gene to rule them all in a chronic brain infection 2020-03-01T05:00:00Z Some scientists are skeptical of the translational potential of this work, however. MDMA Could Be Tailored to Make It More Suitable for Treating Mental Illness 2019-12-11T05:00:00Z Identify the rotational term analogous to each of the following: acceleration, force, mass, work, translational kinetic energy, linear momentum, impulse. College Physics for AP Courses 2015-08-12T00:00:00Z The emergent crystalline structure spontaneously breaks translational symmetry — the symmetry that is associated with the system being uniformly smooth — in such a way that the crystal structure is free to move and vibrate. Sounds of a supersolid detected in dipolar atomic gases for the first time 2019-10-15T04:00:00Z Whereas other NIH institutes and companies study specific diseases, "Our disease is the system: the translational science process," Austin says. Seven years later, NIH center that aims to speed drugs to market faces challenges 2019-09-25T04:00:00Z Adopting a translational perspective, Dr. Schweizer applies insights from basic developmental cognitive neuroscience to design novel interventions for mental health problems including depression and posttraumatic stress disorder. Cultivating Emotion Regulation and Mental Health 2019-09-21T04:00:00Z National laboratories and other federally funded facilities are shared national treasures that have translational value and cannot be overlooked in our progress towards the future. Who Should Pay for "Moon Shots"? 2019-07-16T04:00:00Z Thermal energy is defined to be the average translational kinetic energy KE of an atom or molecule. College Physics for AP Courses 2015-08-12T00:00:00Z As translational researcher Kristi Holmes, director of the Galter Health Sciences Library at Northwestern University and champion of the team-scientist track, explains: “There is a critical need for clear processes to assess data impact.” Credit data generators for data reuse 2019-06-03T04:00:00Z Multidisciplinary efforts require time and sustained funding to foster innovative ideas and drive translational research. After the Integrative Human Microbiome Project, what’s next for the microbiome community? 2019-05-28T04:00:00Z "They want translational research, and they want answers." Long-underfunded lyme disease research gets an injection of money—and ideas 2019-04-17T04:00:00Z Robust governance of controversial translational research must follow multiple strands of reasoning, from science, ethics, social norms, law and common sense. Mary Warnock (1924-2019) 2019-04-16T04:00:00Z The temperature of gases is proportional to the average translational kinetic energy of atoms and molecules. College Physics for AP Courses 2015-08-12T00:00:00Z My project involves translational research, and combines many skills, fields and techniques. Unconscious bias limits women’s careers 2019-03-19T04:00:00Z There is also a master of science in translational research, a course on cell and gene therapies, and Penn Medicine conferences highlighting cell and gene therapies. How Strategic Lab Design Can Accelerate Our Fight against Cancer 2019-03-01T05:00:00Z Assistant professor of systems pharmacology and translational therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia. Technologies to watch in 2019 2019-01-22T05:00:00Z The statement disappointed some by not demanding a strict moratorium, instead calling for “a rigorous, responsible translational pathway toward such trials.” After last week's shock, scientists scramble to prevent more gene-edited babies 2018-12-04T05:00:00Z There is translational motion even for something spinning in place, as the following example illustrates. College Physics for AP Courses 2015-08-12T00:00:00Z The committee also suggested the need for a “translational pathway” that would provide a rigorous and responsible way for researchers to take germline gene-editing to the clinic. First CRISPR babies: 6 questions that remain 2018-11-29T05:00:00Z They also announced plans to set up a “rigorous, responsible translational pathway toward such trials.” Flawed DNA editing of alleged "designer babies" may have put their health at risk 2018-11-29T05:00:00Z Today, a portion of each dollar donated to Hope Scarves goes toward translational research. Why some terminal patients feel alienated by Breast Cancer Awareness Month 2018-10-28T04:00:00Z The beneficial effect of NAD+ augmentation on acute kidney injury observed in that work, although preliminary, illuminates a translational track for NAD+ manipulation. Increased synthesis of a coenzyme linked to longevity can combat disease 2018-10-23T04:00:00Z Here I is analogous to m in translational motion. College Physics for AP Courses 2015-08-12T00:00:00Z The translational aspects of data science — the analysis of big data — promise to benefit individuals, science and society. How to deliver translational data-science benefits to science and society 2018-09-25T04:00:00Z Sixty-two of the papers for which he did not disclose any potential conflict represented “conceptual, basic laboratory or translational work,” and did not require one, he said. Top cancer researcher didn’t list corporate ties when he published studies 2018-09-08T04:00:00Z A more recent example involves quasicrystals, which represent a state of solids that violates translational symmetry. The Power of Anomalies 2018-08-28T04:00:00Z The results suggest that it is possible — and essential — to change how we assess applied and translational research. A better measure of research from the global south 2018-07-03T04:00:00Z Pure translational motion is motion with no rotation. College Physics for AP Courses 2015-08-12T00:00:00Z It would focus on basic research on neural mechanisms underlying cognition, translational studies of neurological diseases with an emphasis on early diagnosis and intervention, and brain simulations to advance artificial intelligence and robotics. Here's how China is challenging the U.S. and European brain initiatives 2018-05-22T04:00:00Z We describe new model systems and translational technologies, as well as the clinical conditions in which new methods may help to combat blindness. Restoring vision 2018-05-15T04:00:00Z Some seek out laboratories that are engaged in highly translational research or that collaborate with partners in industry. How researchers are ensuring that their work has an impact 2018-04-02T04:00:00Z This finding builds the case for investing in scientific integrity, in even the most applied and translational programmes. A better measure of research from the global south 2018-07-03T04:00:00Z Table 10.1 displays rotational quantities, the analogous translational quantities, and the relationships between them. College Physics for AP Courses 2015-08-12T00:00:00Z When discussing a friend’s job in genetic testing, she realized that it fitted with her vision of translational research, even if it did not perfectly match her academic background. How to sail smoothly from academia to industry 2018-03-20T04:00:00Z Companies are especially keen on experience in translational medicine, early-stage clinical trials and antibody manufacturing. Biotech booms in China 2018-01-16T05:00:00Z She suggests that scientists who want to see the impact of their work should seek out labs and companies that do translational research. How researchers are ensuring that their work has an impact 2018-04-02T04:00:00Z “We still do not fully understand the exact translational cascade that TMS starts that ends up fixing depression,” George says. Fighting Depression with Magnets 2017-12-20T05:00:00Z The wheel's rotational motion is exactly analogous to the fact that the motorcycle's large translational acceleration produces a large final velocity, and the distance traveled will also be large. College Physics for AP Courses 2015-08-12T00:00:00Z It will be one of five translational centres through which China hopes to develop cutting-edge medical techniques. Dodgy citations, fusion milestone and a skeleton called Little Foot The work is both a technical achievement and an example of how translational medicine should be conducted. Skin regeneration with insights 2017-11-07T05:00:00Z The money supports training programs, regulatory expertise, and other resources needed to conduct translational research. Senate panel blocks NIH from revising translational research awards 2017-09-26T04:00:00Z I thought people who did translational work were sort of selling out to the man—this was in the 1970s. What's Next after Creating a Cancer-Prevention Vaccine? 2017-09-06T04:00:00Z Work was defined in Uniform Circular Motion and Gravitation for translational motion, and we can build on that knowledge when considering work done in rotational motion. College Physics for AP Courses 2015-08-12T00:00:00Z After all, from the US National Institutes of Health’s translational science centre to the UK’s Research Excellence Framework, scientists are being pushed to demonstrate the impacts of their research. Kill the myth of the miracle machine 2017-07-10T04:00:00Z “Fever seems to be the driving force here,” not the infection itself, said Mady Hornig, director of translational research at the school’s Center for Infection and Immunity. Fever during pregnancy may increase autism risk in offspring 2017-06-13T04:00:00Z Soft soils can amplify them to 10% or more of the magnitude of translational motions. Buried lasers will sense Earth's spin and quakes doing the twist 2017-04-20T04:00:00Z We are so used to doing this translational work. What's Next after Creating a Cancer-Prevention Vaccine? 2017-09-06T04:00:00Z It can also convert translational kinetic energy, when the bus stops, into KErot . College Physics for AP Courses 2015-08-12T00:00:00Z Its six institutes will emphasize translational research and personalized medicine. The Turkish paradox: Can scientists thrive in a state of emergency? 2017-02-14T05:00:00Z “I think what captivated the judges and grabbed our interest is these are translational ideas,” said Jeff Miller, the NFL’s executive vice president for health and safety initiatives. NFL awards $50K to 3 startups to develop safety technology 2017-02-04T05:00:00Z Traditional seismometers can misclassify tilting as translational motion—a problem especially acute for ocean bottom sensors that sit on soft muds, Evans says. Buried lasers will sense Earth's spin and quakes doing the twist 2017-04-20T04:00:00Z This translational and basic research is what NIH does best. What's Next after Creating a Cancer-Prevention Vaccine? 2017-09-06T04:00:00Z To compare kinetic energies, we take the ratio of translational kinetic energy to rotational kinetic energy. College Physics for AP Courses 2015-08-12T00:00:00Z According to a USC website, his laboratory was devoted to studying the “human visual system to address basic and translational questions pertaining to vision loss, restoration, and rehabilitation.” Slain USC professor Bosco Tjan was an expert in vision loss research 2016-12-03T05:00:00Z “This is going to provide China with a tremendous leverage for translational medicine.” Brain implants allow paralysed monkeys to walk 2016-11-08T05:00:00Z These concepts from prion research might challenge conventional thinking and translational research strategies in neurodegeneration. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z One of the biggest nonprofit biomedical research outfits in the world is getting a new translational medicine research arm, aimed at speeding the conversion of basic research insights into novel medicines. Two major California research institutes will merge 2016-10-21T04:00:00Z Repeat Example 10.15 in which the stick is free to have translational motion as well as rotational motion. College Physics for AP Courses 2015-08-12T00:00:00Z The group focuses on boosting private giving to basic research, as pressure intensifies on agencies such as the US National Institutes of Health to fund more applied and translational research. Science group seeks to guide Silicon Valley philanthropists 2016-10-12T04:00:00Z He said he loves the city and hopes to start his own lab in the next year or two focusing on stem cell research and translational therapies. Sanford research team draws scientists from around the globe 2016-09-25T04:00:00Z Placing the brain somewhat in charge appears to "work on the wiring" of the nervous system, said Daniel Lackland, a professor of translational neuroscience at the Medical University of South Carolina in Charleston. New Electrical Stimulation Therapy Can Help Stroke Patients Move Paralyzed Hand 2016-09-08T04:00:00Z Universities and medical schools around the world have established translational research arms in recent years hoping to cash in on basic research discoveries. Two major California research institutes will merge 2016-10-21T04:00:00Z The report finds that Macchiarini’s recruitment to the hospital was mostly driven by the KI’s enthusiasm for his apparently innovative translational research. Culture of silence protected disgraced trachea surgeon 2016-09-01T04:00:00Z Li is the senior associate dean for clinical and translational research at Wake Forest University. U of Illinois names first dean of new medical school 2016-08-30T04:00:00Z The field is also hoping for its first big translational success. Can clinical trials on dogs and cats help people? 2016-08-11T04:00:00Z Four are currently within the WVU Centers for Neuroscience: addiction research; a center for basic and translational stroke research; cognitive neuroscience, and a sensory neuroscience research center. West Virginia University to acquire neuroscience facility 2016-08-02T04:00:00Z But such efforts often stumble, Schultz says, because the culture of basic research, which focuses on insights from individual investigators, is often at odds with translational efforts, which require highly integrated teamwork. Two major California research institutes will merge 2016-10-21T04:00:00Z The translational bridge from animal experiments to human trials is built on the backs of countless volunteers who sign up for a little lab-based agony. Fifty shades of pain 2016-07-12T04:00:00Z The role of the microbiota in shaping adaptive immunity should therefore become an increasingly fertile area for basic and translational investigation. The microbiota in adaptive immune homeostasis and disease : Nature : Nature Publishing Group 2016-07-05T04:00:00Z A neuroscientist explores the brain through basic research and translational medicine. Science stars of China 2016-06-19T04:00:00Z A study in rats is never directly translational to humans. Cell Phone-Cancer Link Seen in Rat Study 2016-05-27T04:00:00Z The German federal government, like most European governments, is pushing translational research in medicine, and its planning can’t be faulted — except for one thing. Monkeying around 2016-04-19T04:00:00Z Relying on their experience in both research and clinical settings, our panelists will discuss the challenges of designing, developing, analytically validating, and employing targeted NGS panels in translational research laboratories. Webinar | Characterizing cancers from liquid biopsies and FFPE samples: The rise of targeted sequencing panels AUDIO | Science 2016-04-07T04:00:00Z "There will be lots of benefits for immediate use, as well as for translational science,'" he said. Promising lab-grown skin sprouts hair and grows glands - BBC News 2016-04-01T04:00:00Z By supporting a broad portfolio of basic, translational, population, and clinical research, NIH will continue to lead the way toward a healthier future. Basic science: Bedrock of progress | Science 2016-03-24T04:00:00Z Next, monkeys employed the wireless BMI to translate their cortical activity into the robotic wheelchair’s translational and rotational velocities. Watch This Monkey Control a Wheelchair With Its Tiny Monkey Brain 2016-03-03T05:00:00Z “The brain uses both neurotransmitters and electric fields to communicate,” says Sarah Hollingsworth Lisanby, director of the division of translational research at the National Institute of Mental Health in Bethesda, Maryland. Neurostimulation: Bright sparks : Nature : Nature Publishing Group 2016-03-01T05:00:00Z When Obama and Clinton backed up their challenges to find cures with proposals to increase funding for research by $1-2 billion, they were talking about translational research, echoing calls for these "smarter" investments in science. To Cure Cancer, Start Simply 2016-02-22T05:00:00Z He supports funding for translational medicine, but cautions that without continued support for basic research, there might be nothing to translate. Drug discovery: A life of tumult and triumph : Nature : Nature Publishing Group 2016-02-09T05:00:00Z She says the university is planning a translational science complex - a field that includes medicine, brain science, bioengineering, computer science, and big data. Plans for new Providence research facilities unveiled 2015-11-24T05:00:00Z Abdellatif Benraiss, a translational neuroscientist at the University of Rochester in New York who is not involved with the research, cautions that the current technique is not poised for that kind of longevity. Gene-editing method halts production of brain-destroying proteins 2015-10-20T04:00:00Z The work, Bale says, has “immediate translational effects”. The tantalizing links between gut microbes and the brain 2015-10-13T04:00:00Z A fourth researcher, Julia Stephen of the Mind Research Network, is an associate professor of translational neuroscience. 3-state project to look at developing adolescent brains 2015-10-08T04:00:00Z “He is one of our nation’s leaders in the growing field of translational research, which is key to ensuring that advances in science translate into medical care.” Who Is the New Head of the FDA? 2015-09-16T04:00:00Z Kay says that while he values the independence of the faculty, more alliances will probably be in the offing as he and Schultz try to position Scripps as a translational research powerhouse. Scripps Research Institute appoints leadership duo 2015-09-17T04:00:00Z Antman is a professor and associate dean for clinical/translational research at Harvard Medical School in Boston. People in Their 50s Benefit Most From Low-Dose Aspirin, Report Says 2015-09-14T04:00:00Z Successful translational research depends on many factors, says Xiao Ruiping, a physiologist and director of the Institute of Molecular Medicine at Peking University in Beijing. Research impact: A tale of two systems : Nature : Nature Publishing Group 2015-04-28T04:00:00Z This is important not only for its effects on basic research, but also because of the potential for translational research to founder if cell lines are contaminated. Announcement: Time to tackle cells’ mistaken identity 2015-04-14T04:00:00Z "It is clearly a better test than what we're currently using," said study lead author Dr. Mary Norton, a professor and vice chair of clinical and translational genetics at the University of California, San Francisco. Newer Test for Down Syndrome Called 'Major Advance' 2015-04-01T04:00:00Z When you talk about translational medicine, a drug usually moves from “bench to clinic.” Seeking the Facts on Medical Marijuana 2015-03-23T04:00:00Z These are examples of the fruits of "translational research," or engineering conducted at the lab bench with an eye toward rapidly getting it to customers or, in a medical context, to the bedside. Engineering Programs Work to Get Research from Lab to Customers 2015-03-19T04:00:00Z Hospitals such as the new Shanghai translational centre, which are affiliated with universities or medical colleges, may be able to get around this barrier by recruiting staff through their affiliates. Research impact: A tale of two systems : Nature : Nature Publishing Group 2015-04-28T04:00:00Z Sigal and others are enthused about Califf’s wide experience in running clinical trials at Duke, where he is currently vice chancellor of clinical and translational research. Clinical-trial specialist could be next FDA chief 2015-02-11T05:00:00Z Singleton said the use of translational medicine to develop treatments for cancer and other diseases could be accelerated by taking advantage of Northern Virginia’s expertise in cloud computing and data analytics. Inova plans giant cancer, genomics medicine complex in Fairfax 2015-02-06T05:00:00Z And so, “with a little translational trickery, a fundamental tenet of Christianity—that Jesus is God—was reinforced in the Bible, even in places where it directly contradicts the rest of the verse.” A Response to Newsweek on the Bible Plump is an expert in biomarker development and translational research more generally. Quick Update: New Hires, Recent Panel Discussion Emphasize Confluence Of Pharma And Big Data 2014-12-24T05:00:00Z The downstream businesses that are essential in supporting the translational medicine ecosystem are also unformed. Research impact: A tale of two systems : Nature : Nature Publishing Group 2015-04-28T04:00:00Z In other words, with a little translational trickery, a fundamental tenet of Christianity—that Jesus is God—was reinforced in the Bible, even in places where it directly contradicts the rest of the verse. The Bible: So Misunderstood It's a Sin “One element we found very difficult was this translational aspect,” Gates acknowledged. After 10 years, few payoffs from Gates ‘Grand Challenges’ 2014-12-20T05:00:00Z Third, this is not a matter of “translational trickery” or “manipulation.” A Response to Newsweek on the Bible A recent overview of the new program explains that the same grantmaking model will eventually extend to two other funding categories—“discovery” and “translational.” California stem cell agency to launch new speedy funding mechanism 2014-12-12T05:00:00Z The Shanghai centre is the first in a series of projects for translational medicine from the government's National Science and Technology Infrastructure programme. Research impact: A tale of two systems : Nature : Nature Publishing Group 2015-04-28T04:00:00Z A lot of research now is trying to be very translational, focused on helping people with different diseases. New Allen Cell Observatory, With $100 Million, Promises Animated View Of Cell Behavior 2014-12-08T05:00:00Z The foundation decided to launch a translational award. Cystic Fibrosis Charity Sells Drug Rights To Pharma For $3.3 Billion 2014-12-05T05:00:00Z The university has lured Venkat Selvamanickam back to work on translational research, something the nation’s best universities, from Stanford to Duke, have done for years. New energy fuels school’s ambitions 2014-11-24T05:00:00Z They’ve put in a lot of financial support, not only in the early stage academic research but also translational medicine and the biotech industry. MedidataVoice: J&J Is On The Hunt For Chinese Innovation 2014-11-18T05:00:00Z The main goal of the translational medicine centres is to more efficiently transform basic biomedical research into clinical applications, including new diagnostics, treatments and drugs. Research impact: A tale of two systems : Nature : Nature Publishing Group 2015-04-28T04:00:00Z “It is very important for the centre to steer away from bureaucratic red tape and stay focused on its mission and long-term vision of conducting high-impact translational research.” China opens translational medicine centre in Shanghai 2014-10-28T04:00:00Z These are both good examples of what we call translational science, whereby basic knowledge is used to develop tests and treatments for the benefit of patients. Q&A: Francoise Barre-Sinoussi : Nature : Nature Publishing Group 2014-10-14T04:00:00Z Steven Buchsbaum, deputy director of discovery and translational sciences for the Gates Foundation, talked to Nature about the lessons learnt from ten years of Challenges. Gates Foundation Challenges turn ten 2014-10-06T04:00:00Z More focus is also being put on translational research. MedidataVoice: J&J Is On The Hunt For Chinese Innovation 2014-11-18T05:00:00Z Startups – as I argued in 2005 – represent, in a sense, the purest distillation of the translational research ideal. Why Physicians Are Turning To Startups 2014-08-05T04:00:00Z Funding agencies should establish committees of translational scientists to review which markers of biological ageing are most consistent between animals and humans, and prioritize the most practical for further assessment. Medical research: Treat ageing 2014-07-22T04:00:00Z There is a great need for new foundational and translational technologies and tools and need for fundamental research in biology in terms of how it actually works and how we understand it. Engineering Biology to Address Global Challenges 2014-06-27T04:00:00Z Even key funding agencies such as the US National Institutes of Health are shifting towards more translational research. Universities seek to boost industry partnerships 2014-05-07T17:20:19.738Z So more focus and money are being put into translational medicine. MedidataVoice: J&J Is On The Hunt For Chinese Innovation 2014-11-18T05:00:00Z For a given input of energy, vibrational energy was more effective for surmounting the reaction barrier than translational energy. [Report] Vibrationally Promoted Dissociation of Water on Ni(111) 2014-05-01T18:26:34.338Z Steven Epstein is a pioneering gene therapy and stem cell researcher who is currently the director of translational and vascular biology research at the MedStar Heart Institute. Stem Cell Therapy To Fix The Heart: A House Of Cards About To Fall? 2014-04-28T23:25:00Z The only known exception is the transient translational repression observed in early zebrafish embryos. Poly(A)-tail profiling reveals an embryonic switch in translational control 2014-04-04T22:51:04.645Z But the emerging picture reveals great challenges ahead for translational neurobiology. Perspective: Revealing molecular secrets 2014-04-02T17:21:26.216Z This is going to lead to an entire new set of questions that need to be evaluated in a very basic manner, as well as in a translational manner. Translational research: Cancer killers 2014-04-02T17:20:46.199Z The reaction occurs via a direct pathway, because both the translational and vibrational energies promote the dissociation. [Report] Vibrationally Promoted Dissociation of Water on Ni(111) 2014-05-01T18:26:34.338Z As the new cystic fibrosis treatment emerged, he pressed the government to adopt the breakthrough translational method, federal budget cuts notwithstanding. Billionaires With Big Ideas Are Privatizing American Science 2014-03-15T20:24:24Z These regression results were used to estimate the translational efficiency change attributable to tail-length change for each gene. Poly(A)-tail profiling reveals an embryonic switch in translational control 2014-04-04T22:51:04.645Z Tanshinone IIA blocked proinflammatory signals in vivo, and its effects are conserved in human neutrophils, supporting a potential role in treating human inflammation and providing compelling evidence of the translational potential of this screening strategy. [Research Articles] A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism 2014-02-26T19:25:21.240Z As a graduate student, I wasn't really able to do the translational aspects directly, she recalls. Translational research: Cancer killers 2014-04-02T17:20:46.199Z We developed an integrative biology approach combining human disease transcriptome data sets with clinically relevant in vivo models in an attempt to bridge this translational gap. [Research Articles] Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis 2014-02-12T19:25:12.939Z The success begot a global rush to turn basic discoveries into treatments, a field now known as translational science. Billionaires With Big Ideas Are Privatizing American Science 2014-03-15T20:24:24Z Global measurements indicate that miRNA targeting causes mostly mRNA destabilization, with translational repression comprising a detectable but minor component of the overall repression. Poly(A)-tail profiling reveals an embryonic switch in translational control 2014-04-04T22:51:04.645Z And opportunities for translational research are growing thanks to recent technological breakthroughs. Biomedicine: The changing face of primate research 2014-02-05T18:21:10.713Z Many in the field agree that those who stay at academic institutions must learn how to conduct translational research in a culture and environment that may be unaccustomed to supporting such work. Translational research: Cancer killers 2014-04-02T17:20:46.199Z It’s their translational clinical group, which collaborates on a bunch of projects with a lot of the New York institutions. The 30-Minute Interview Joel S. Marcus: Joel S. Marcus 2014-01-15T02:00:27Z Today, the N.I.H. translational science center has an annual budget of more than $600 million and seeks new drugs for rare diseases, which number in the thousands. Billionaires With Big Ideas Are Privatizing American Science 2014-03-15T20:24:24Z The thing that really attracted me, though, was seeing translational medicine happen in my lifetime. A Conversation With Holbrook Kohrt: A Doctor’s Intimate View of Hemophilia 2013-12-23T22:51:43Z In 2000, Switzerland's constitution was changed to protect the dignity of animals — a move that led courts to limit the use of monkeys to translational research. Biomedicine: The changing face of primate research 2014-02-05T18:21:10.713Z Cooper therefore encourages graduate students to earn their PhD by investigating the more fundamental research questions in cancer immunotherapy, then waiting until their postdoc or later to pursue the translational angle. Translational research: Cancer killers 2014-04-02T17:20:46.199Z We are redefining how translational medicine is practiced. The Future Of Translational Medicine -- Lessons Learned In Therapeutics 2013-12-23T17:47:00Z In gene sequencing, in translational medicine, in the Obama administration’s Brain initiative and in other areas, the federal government, instead of setting the agenda, increasingly follows the private lead. Billionaires With Big Ideas Are Privatizing American Science 2014-03-15T20:24:24Z With burgeoning interest in translational research, structural biology, and regenerative medicine, many scientists are starting to think bigger. [Business Office Feature] LIFE SCIENCE TECHNOLOGIES Living Large: Scaling Up Cell Culture 2013-12-05T18:57:44.026Z Steven Buchsbaum, who leads the discovery and translational sciences team at the Gates Foundation, said he expects the creation of the disease database to prompt other efforts like it. Researchers at University of Pittsburg create digital database of infectious diseases 2013-11-27T22:00:07Z I start with the opposite premise of the usual translational thinking. Do Drug Companies Suffer From Premature Translation - And Can Google's Calico Cure It? 2013-11-23T00:31:00Z We’ve learned that translational medicine is not just about the science. The Future Of Translational Medicine -- Lessons Learned In Therapeutics 2013-12-23T17:47:00Z It emphasizes the pursuit of translational research in federal science agencies, and partnership with private funding sources. Republicans Put 'National Interest' Requirement on National Science Foundation 2013-11-07T11:45:00.477Z These cases led to calls for examination of the field of translational omics. Criteria for the use of omics-based predictors in clinical trials 2013-10-16T17:22:00.073Z Dismayed by her financial burden and the bleak job prospects in academia, Stemler is planning to move into translational medicine and then, she hopes, into cancer-diagnostics research at a biotechnology or pharmaceutical company. Education: Financial burden 2013-09-25T17:20:46.910Z First, as I’ve noted, industry, and translational research more generally, plays a vital role in pressure-testing the conclusions of basic science. Do Drug Companies Suffer From Premature Translation - And Can Google's Calico Cure It? 2013-11-23T00:31:00Z This Insight covers some of the key topics relevant to the fast-moving field of cancer research, ranging from the basic understanding of tumour heterogeneity to translational cancer research and clinical trials. Tumour heterogeneity 2013-09-18T17:21:11.727Z Adequate resources for FDA are a vital link in the translational chain, and sequestration is a threat to the health and welfare of everyone. [Editorial] Sequester Cuts May Delay Drug Approvals--And More 2013-09-04T18:25:02.897Z This multi-faceted program includes 1,200 principal investigators and more than 4,000 postdoctoral fellows who conduct basic, translational and clinical research at 23 NIH centers. Making cancer drugs more effective 2013-09-03T13:18:31Z However, because many existing cost-effective interventions are not widely used, there is a particular need for translational studies that turn existing knowledge into practical applications. [Editorial] Research for Universal Health Coverage 2013-08-21T18:25:01.320Z In 2001, I was hired to work in the then-new molecular-oncology division at Washington University in St. Louis, where researchers were mixing genomics with cancer biology and making the translational jump to the clinic. Turning point: Jason Weber 2013-08-21T17:50:36.117Z Yet the linking of such data is instrumental for the advancement of translational medicine. [Editorial] Regulating Genomics: Time for a Broader Vision 2013-08-14T18:25:06.270Z There wasn’t a translational science trajectory from non-randomized studies to randomized trials, for example. Nutrient X prevents disease? Sorting the wheat from the bran 2013-07-31T14:15:05.530Z He called the “OsseoPulse” procedure a “great example of translational basic research from bench, to bedside and beyond culminating in a useful product”. Fighting Tooth and Claw with Wolverine Examining the Healing Power of an X-Man 2013-07-27T01:45:07.323Z For the record, I work for a government-funded research network that was created 12 years ago with mandate to bridge the gap between basic and clinical studies: in other words, to fund translational research. This Research Is worse Than Bad. It's Basic 2013-07-24T15:15:09.673Z There are physicists who see little excitement in anything larger than an atom, and translational biologists who consider finding disease treatments the only worthwhile task. "I Don't Know If I'm a Scientist": The Problem with Archetypes 2013-07-10T15:15:03.567Z Belgium will offer one early-career grant to support work in cancer or translational research. Fulbright Program Reaches Out to Scientists 2013-07-03T22:58:42Z “It’s turning back the clock,” said Dr. Clifford J. Rosen, director of clinical and translational medicine at the Maine Medical Center in Portland. who led the advisory committee on the drug in 2007. Second Thoughts on Safety of Avandia Stir a Dispute 2013-06-02T19:41:49Z During yesterday's kickoff meeting, the institutes shared their experiences in human resources, funding, technology transfer, science communication, and translational research. Top European Life Science Institutes Join Forces 2013-05-30T22:30:00Z For example, the Singapore Translational Research Investigator Award from the National Medical Research Council is meant to attract experienced scientists to do translational and clinical research in Singapore. Working in Asia: The siren song of Singapore 2013-05-15T17:21:09.080Z Kormuro’s research explores “the molecular mechanisms underlying mutual regulation between cardiovascular cells and the immune system including mast cells and T lymphocytes and advance translational research.” Suspicions Raised About Another Japanese Cardiovascular Researcher 2013-05-10T21:09:05Z I called the NIMH, and was put on the phone with Bruce Cuthbert, the director of the division of adult translational research. Why Psychiatry's Seismic Shift Will Happen Slowly 2013-05-08T13:43:06Z Daniel Rader, chief of the division of translational medicine at the University of Pennsylvania’s Perelman School of Medicine, says that the drug’s efficacy is “impressively good.” In Moribund Cholesterol Field, A New Drug Emerges 2013-04-25T12:44:45Z Investment would continue to flow to translational science at the Energy Innovation Hubs and Energy Frontier Research Centers initiated by departing energy secretary Steven Chu. A back seat for basic science 2013-04-17T17:20:18.603Z “I thought the PCSK9 story was a terrific example of an up-and-coming pattern of translational research” — indeed, he adds, “a harbinger of things to come”. Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z Susan Fisher, director of translational research in perinatal biology and medicine at the Center for Reproductive Sciences of the University of California, San Francisco, says that adaptability gives her graduates a leg up in industry. Reproductive biology: Breeding opportunities 2013-03-20T18:20:44.407Z Professor of biostatistics and associate dean for clinical and translational science, Harvard School of Public Health raised some advantages for adaptive clinical trials and for accelerated approvals based on surrogate markers. Covering Clinical Trials: a message for journalists and critical readers 2013-03-20T11:45:02.097Z For example, he leads the NIH Scientific Management Review Board, which was asked in 2010 to assess plans for a new translational research centre. America’s research adviser: Science's go-to guy 2013-02-27T18:20:54.603Z If you wanted me to pick a quarterback, this is the quarterback I'd pick,” says Lee Nadler, director of Harvard Catalyst, the NCATS-funded clinical and translational science centre based at Harvard University in Boston, Massachusetts. Translational research: Medicine man 2013-02-06T18:21:06.503Z “The PCSK9 story is a terrific example of an up-and-coming pattern of translational research.” Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z This is a great time to be in early stage translational research, and I’m hopeful the FDA, the public markets, and the funding environment continue to trend favorably. Early Stage Biotech Showing Positive Signs of Scaling Its Wall of Worry 2013-01-15T18:04:40Z Lack of animal models with human-like size and pathology hampers translational research in atherosclerosis. [Research Articles] Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant 2013-01-02T19:55:06.297Z “I never heard from Norm,” says Berg, the only person on the board who opposed the creation of the translational medicine institute. America’s research adviser: Science's go-to guy 2013-02-27T18:20:54.603Z That means forcing the agonizingly slow, failure-prone process of 'translational research' — the term of art for moving promising discoveries from the lab to the clinic — into a higher gear. Translational research: Medicine man 2013-02-06T18:21:06.503Z To emphasize the primitive genetic and translational mechanisms of the earlier, simpler cells, I call them progenotes. Archaebacteria: The Third Domain of Life Missed by Biologists for Decades 2013-01-01T00:45:00.170Z That includes those from a request for applications for early translational awards that closed on 14 December. Texas Cancer Agency Halts New Grants 2012-12-20T17:50:00Z This model should prove useful for several types of translational research in atherosclerosis. [Research Articles] Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant 2013-01-02T19:55:06.297Z The paradox is that you've got fantastic, science-led translational research helping this group of patients with severe disease, but there's a disconnect in understanding how to manage the patient as an individual. Q&A: Under their skin 2012-12-19T18:21:02.857Z By November, Austin was in place as Collins's senior adviser for translational research. Translational research: Medicine man 2013-02-06T18:21:06.503Z One possible criticism of these centres and of academia-focused translational science programmes is that some are run by academics without industrial drug-discovery expertise. Drug discovery: A helping hand 2012-12-05T18:50:38.353Z The perils of translational research This is an updated and revised version of an article I wrote for the Lindau Meeting of Nobel laureates and Current Science magazine. The perils of translational research 2012-11-26T18:45:13.717Z Currently, there’s a tremendous focus on translational medicine, generally understood as the need to ensure molecular advances in the laboratory are turned into better care at the bedside. The Mentalists: Behavioral Psychology Delivered Votes -- Can It Now Deliver Health? 2012-11-13T03:36:24Z Austin, 52, a developmental neurogeneticist who spent 7 years at Merck before joining NIH to oversee translational programs at NIH's genome institute, seemed undaunted by the criticism in an interview with Insider last week. NIH's New Translational Chief on How to Solve Pharma's Woes 2012-11-06T17:12:37Z The New York conference was held at Rockefeller University on 10 and 11 October, an annual gathering to discuss translational stem cell research sponsored by The New York Stem Cell Foundation. Breakthrough Stem Cell Results Called Into Question 2012-10-12T20:57:47Z One way to move into translational research is through postdoctoral fellowships sponsored by companies such as Roche, the Novartis Institute for Biomedical Research headquartered in Cambridge, Massachusetts, or Genentech, headquartered in South San Francisco, California. Drug discovery: A helping hand 2012-12-05T18:50:38.353Z Because I believe it strikes at the heart of what these days is fashionably called “translational research”. The perils of translational research 2012-11-26T18:45:13.717Z Another key element is a balanced portfolio that appreciates the complementary value of basic, translational, clinical, and population science. Fostering Diversity, Heading Off Heart Disease 2012-09-25T17:00:00Z That applies to individual steps in the translational process, which are remarkably empirical even today. NIH's New Translational Chief on How to Solve Pharma's Woes 2012-11-06T17:12:37Z At the time, the company said it would open a new translational clinical research center somewhere on the East Coast. Roche, Swiss Pharmaceutical Giant, to Open Research Center in Manhattan 2012-09-20T04:02:30Z A small percentage would then stay in the translational centres, working as the next generation of trainers. Drug discovery: A helping hand 2012-12-05T18:50:38.353Z Just like physics research was being viewed through the lens of national defense in the 60s, basic biomedical studies run the risk of being viewed through the lens of translational research in the 2010s. The perils of translational research 2012-11-26T18:45:13.717Z In 2002, he left to become adviser for translational research at the National Human Genome Research Institute, where Collins was then director. NIH Looks Within for New Translational Center Chief 2012-09-14T22:26:00Z Right now, the vast majority of cancer treatments that work in mice fail in people, said immunologist Carl June, director of translational research at Penn's Abramson Cancer Center. Researchers enlist dogs in battling human cancers 2012-07-24T04:37:26Z The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational research. [Research Articles] Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics 2012-07-11T18:55:04.923Z They are starting up translational medicine programmes to teach aspects of drug discovery. Drug discovery: A helping hand 2012-12-05T18:50:38.353Z The goal of translational research especially in medicine seems to transform basic biomedical research discoveries from “bench to bedside”. The perils of translational research 2012-11-26T18:45:13.717Z Here, we discuss preclinical DBS research that provides insight into the mechanisms underlying cognitive and psychiatric applications of this technique, emphasizing the predictive validity of animal models and their potential use in translational research. [Reviews] Deep Brain Stimulation for Psychiatric Disease: Contributions and Validity of Animal Models 2012-07-11T18:55:01.370Z Burberry is also at a disadvantage to euro reporting peers who benefit from stronger translational currency impact. Burberry shares drop 5% as sales growth slows 2012-07-11T08:31:14Z His work in UCSD’s translational oxytocin research program aims to find clinical applications for this attachment hormone, as well as investigate its role in psychotherapy. Why Do We Say That Someone is “Hot”? 2012-07-10T11:45:00.200Z In a climate of increased expectation for the translation of research, academic clinical research units are looking at new ways to streamline their operation and maintain effective translational support services. [Commentary] From Free to Free Market: Cost Recovery in Federally Funded Clinical Research 2012-07-04T18:25:01.317Z Not surprisingly, the press has eagerly jumped on the bandwagon, with reports pitching translational research and personalized medicine regularly appearing in the nation’s leading papers. The perils of translational research 2012-11-26T18:45:13.717Z The importance of advocacy groups in translational research—making the link between basic science and useful applications for patients—is well-illustrated by the PXE International organization. Clinical Trials for Beginners: Recipe for a new drug 2012-06-26T16:15:05.180Z These results thus delineate the range of structural and functional configurations normal in the microbial communities of a healthy population, enabling future characterization of the epidemiology, ecology and translational applications of the human microbiome. Structure, function and diversity of the healthy human microbiome 2012-06-13T17:20:54.030Z Called an ‘incubator’ grant, its aim was to provide expert technical and business assistance to Texas-based translational research projects and start-ups. Grant review opens up Texas-sized rift 2012-06-13T17:20:24.503Z With budgets forcing reductions in government spending on science research around the world, industry is increasingly stepping in to fill the gap, especially in translational and clinical studies. The power of transparency 2012-04-04T21:51:59.370Z Echoing leading scientists, the press seems to be telling us that we should all look forward to supporting translational research in its various guises. The perils of translational research 2012-11-26T18:45:13.717Z Sawyers expects much of the research to be translational. New York fellowships 2012-01-11T18:20:58.677Z The most abundant of these ‘core’ pathways include the ribosome and translational machinery, nucleotide charging and ATP synthesis, and glycolysis, and reflect the basics of host-associated microbial life. Structure, function and diversity of the healthy human microbiome 2012-06-13T17:20:54.030Z These large grants support translational research at some 60 academic medical centers. Acting Director Thomas Insel Explains New NIH Translational Center's Aims and Structure 2012-01-10T15:53:30Z It is really the manifestation of the pressure or thrust aspect of the work energy, just as the kinetic energy is the manifestation of the translational or velocity aspect. The Energy System of Matter A Deduction from Terrestrial Energy Phenomena 2011-12-21T03:00:36.570Z All this makes the idea of translational research sound promising. The perils of translational research 2012-11-26T18:45:13.717Z However, limitations in public reporting preclude the tracing of outcomes from secondary research to longer-term translational benefit. [Commentary] dbGaP Data Access Requests: A Call for Greater Transparency 2011-12-14T20:25:06.567Z Funders are pouring significant money into translational projects, providing an opportunity for young scientists applying for grants. Life sciences: Biomarkers on the brain 2011-11-02T18:20:44.333Z Here, we provide an overview of recent developments in synthetic biology in the context of translational research and discuss challenges at the interface between synthetic biology and clinical medicine. [Perspectives] From DNA to Targeted Therapeutics: Bringing Synthetic Biology to the Clinic 2011-10-26T19:55:05.177Z The Lieber Institute for Brain Development in Baltimore, Mary-land, dedicated to translational research in neurodevelopmental diseases, which opened formally this year, is building a collection of young brains to support its research programme. A priceless resource 2011-10-26T17:20:01.060Z What is wrong is that translational research is being seen as a panacea that will address the flagging rate of new biomedical advances. The perils of translational research 2012-11-26T18:45:13.717Z Don Cooper can speak Spanish, and Jackson Miranda, the Sox's director of cultural development, assists Spanish-speaking players who may need some translational assistance. Q&A: Gonzales' White Sox mailbag 2011-10-19T01:25:00Z An interview with the oncologist, translational scientist and former Genentech executive now leading the University of California, San Francisco. SCIENCE: Susan Desmond-Hellmann 2011-10-17T21:07:39Z Increasingly sophisticated, rationally designed synthetic systems that are capable of complex functions pave the way to translational applications, including disease diagnostics and targeted therapeutics. [Perspectives] From DNA to Targeted Therapeutics: Bringing Synthetic Biology to the Clinic 2011-10-26T19:55:05.177Z Lee Nadler, dean for clinical and translational research at Harvard Medical School, says that helping clinicians prognosticate disease or adverse outcomes to medicine will be crucial. Translational research: The American way 2011-10-12T17:21:08.897Z The first problem is that history is not really on the side of translational research. The perils of translational research 2012-11-26T18:45:13.717Z If we shift mostly to translational research, the springs of knowledge will dry up, and there will be nothing left to translate. On the wings of imagination 2011-10-12T17:20:56.877Z The Senate bill also establishes and funds a proposed translational medicine centre at the NIH, but the House bill does not mention it. Seven days: 30 September?6 October 2011 2011-10-05T17:20:18.957Z By reporting the results of clinical trials of abandoned products in a publicly accessible database and in the peer-reviewed journal literature, sponsors would satisfy a core ethical obligation of clinical research and enhance translational science. [Commentary] Disclosure of Clinical Trial Results When Product Development Is Abandoned 2011-09-28T20:25:32.283Z Barriers to translation include the need not only for improved compounds but also for improved biomarkers sensitive to both structural and functional target engagement and for improved translational models. [Meeting Reports] Translating Glutamate: From Pathophysiology to Treatment 2011-09-28T20:25:01.443Z The second more practical but equally important problem with translational research is that it puts the cart before the horse. The perils of translational research 2012-11-26T18:45:13.717Z “The disappearance of physician-scientists threatens the very essence of what we call translational research, because if not for them, who would be left to translate anything?” Clinical science: Research and repair 2011-08-17T21:50:32.687Z "There is no alternative treatment that works very well, whether it's a drug or over-the-counter herbal preparation," said Dr. Deborah Grady, associate dean for clinical and translational research at the University of California, San Francisco. Hormones may be only option for some in menopause 2011-08-16T20:46:06Z “There is no alternative treatment that works very well, whether it’s a drug or over-the-counter herbal preparation,” said Dr. Deborah Grady, associate dean for clinical and translational research at the University of California, San Francisco. Well: For Some in Menopause, Hormones May Be Only Option 2011-08-15T22:15:18Z To conduct high-quality state-of-the-art research, clinical and translational scientists need access to specialized core facilities and appropriately trained staff. [Commentary] Core Facilities: Maximizing the Return on Investment 2011-08-10T20:25:03.783Z Chalfie, Steitz and others like them are also right to criticize the frenzy that translational research generates in the popular press. The perils of translational research 2012-11-26T18:45:13.717Z The institute's core focus is on systems and translational neuroscience, including developing treatments for Parkinson's disease and spinal cord injuries, and most of those who left did research in other areas. Mass Exodus Roils Brazilian Neuroscience Institute 2011-08-09T20:18:22Z Researchers later discovered that what seemed to be new was actually old: the same pattern, which lacks the translational symmetry of a true crystal, appears in an Iranian shrine built in 1453. Mexico City Journal: Bathed in Light, a Locus of Sadness Begins to Heal 2011-07-18T00:16:26Z To pursue opportunities for disruptive translational innovation, the U.S. [Commentary] Reengineering Translational Science: The Time Is Right 2011-07-06T20:25:07.827Z In this time of economic constraints and increasing research costs, organized and efficient core facilities are essential for researchers who seek to investigate complex translational research questions. [Commentary] Core Facilities: Maximizing the Return on Investment 2011-08-10T20:25:03.783Z Needless to say, committing national resources and public attention to translational research when most of the basics are still to be understood is an endeavor fraught with great risk and uncertainty. The perils of translational research 2012-11-26T18:45:13.717Z But there are programmes that need to be undertaken as community efforts because they are expensive and difficult, yet promise advances: the renovated clinical-trials system, genomic studies and certain translational activities. NIH cancer chief wants more with less 2011-07-06T17:20:17.130Z He believes that translational process requires breaking down compartments of expertise and working together among government agencies, academia and industry as well as across disciplines. New Report Details Uphill Battle to Solve the U.S.'s Pain Problem 2011-07-01T22:15:00.293Z “At present, there is no translational facility like this in the Midwest.” Scientists Use 3-D Display to Study Molecules 2011-06-16T14:48:00Z Lawmakers also quizzed the NIH chief about his plan to create a new center for translational research. NIH Director: Fewer Than One in Five Grant Applications Could Go Unfunded This Year 2011-05-11T22:25:45Z Industry also seems to place a premium on scientists with experience in translational research, says GuhaThakurta. Systems immunology: Complexity captured 2011-05-04T17:20:54.117Z What balance of basic, translational and clinical research are you seeking at the NCI to conquer cancer as quickly as possible? NIH cancer chief wants more with less 2011-07-06T17:20:17.130Z But NIH needs some money to get CAN started as part of a new center for translational research. 2011 Spending Deal Spares NIH Major Cuts 2011-04-12T17:55:01Z Furthermore, beyond its defined study end points, this well-conducted trial identified new research directions that should be pursued in smaller intensive basic and translational studies. [Perspectives] HIV Transmission: Time for Translational Studies to Bridge the Gap 2011-04-06T18:55:06.473Z It has drawn in many cancer biologists who are excited by the potential to translate their work to the clinic — but they sometimes lack the expertise or resources needed to pursue translational or clinical work. Cancer: Missing the mark 2011-03-23T18:51:20.700Z We'd built a stem cell program from scratch starting with the basic research and building up the translational side. Q&A With Australia-Bound Stem Cell Ace 2011-03-21T16:04:35Z Translational research in medicine is necessarily a team-based endeavor, and, indeed, translational research teams often include researchers from many different disciplines. [Commentary] How Inclusion of Genetic Counselors on the Research Team Can Benefit Translational Science 2011-03-16T19:55:03.200Z The money will be reserved for projects described as "translational research" - defined as those which will directly benefit patients. ?775m funds for health research 2011-03-07T00:48:42Z A major factor is the overemphasis on so-called translational research, which seeks to translate laboratory findings into clinical applications, at the expense of basic research. Letters: Before We Look for Cures (1 Letter) 2011-02-28T23:35:00Z An institute director at the National Institutes of Health sounded off today about NIH's its infrastructure center in order to launch a new center for translational science. Dissent in NIH's Ranks 2011-02-22T22:26:52Z She performs and publishes both basic and translational research, teaches in the lecture hall and clinic, and cares for patients in her specialty. Paradoxical Polyuria--when it comes to kidneys, sometimes more is less 2011-02-10T17:15:05.450Z Will they say they're excited about the translational science opportunities that are taking shape in the form of this new center? NIH's Collins Explains Why NCRR Must Go 2011-01-21T22:56:40Z The effort to use what we are learning about how cells and organisms work at the molecular level to improve human health is often called “translational medicine.” [Editorial] Model Organisms and Human Health 2011-01-05T01:55:03.187Z The push for translational studies by the National Institutes of Health, Congress and our universities is shortsighted and damaging. Letters: Before We Look for Cures (1 Letter) 2011-02-28T23:35:00Z Clinical research Participation in specialty-specific research activities such as clinical trials and other translational research. Best Children's Hospitals 2010-11: Behind the Terms 2010-06-02T22:00:00Z "To accelerate progress in biomedical research, NIH investments will focus on priority areas including genomics, translational research, science to support health care reform, global health, and reinvigorating the biomedical research community," the budget reads. 2010-02-01T15:32:00Z Reaching his cabin, he sat for some time at the small table where he carried on his writing and translational work. The Frontiersman A Tale of the Yukon It is not thus with other forms of energy than the translational. The Machinery of the Universe Mechanical Conceptions of Physical Phenomena The average effect of repeated and repeated mutual collisions must be to gradually convert all the translational energy into energy of shriller and shriller vibrations of the molecule. Scientific American Supplement, No. 460, October 25, 1884 Clausius has even estimated the relative importance of these two quantities, showing that the translational motion of a molecule of gas accounts for only three-fifths of its kinetic energy. A History of Science — Volume 3 In the gaseous state, as we have seen, the translational motion of the molecules is relatively enormous, the molecules being widely separated. A History of Science — Volume 3 But it is clearly conceivable that a stage might be reached at which the molecules became absolutely quiescent, as regards either translational or vibratory motion. A History of Science — Volume 3 As the ether cannot be heated and cannot transform translational energy, it is without inertia for such a form of motion and its embodied energy. The Machinery of the Universe Mechanical Conceptions of Physical Phenomena |
| 随便看 |
英语例句辞典收录了117811条英语例句在线翻译词条，基本涵盖了全部常用单词及词组的例句翻译及用法，是英语学习的有利工具。