As the estrogen is combined with osteoclast, it can inhibit the activity of lysomal enzyme, inhibit bone resorption and decrease the ability of osteclast on forming cavate in bone slice.

作用于破骨细胞则抑制其溶酶体酶的活性，抑制骨吸收，并降低其在骨切片上产生凹陷的能力。