In chronic disease states, chemical messengers called cytokines mediate this pathologic process in the kidney, immune system, and the GI tract.

在慢性疾病中，称为细胞因子的化学信使在肾脏、免疫系统和胃肠道中介导了这一病理过程。

We need to act early and put in place early mediating processes.

我们需要尽早采取行动并尽早建立调解程序。