Generally speaking, malignant cells are irregularly-shaped with darkly staining nuclei, enlarged nucleoli, and produce abnormal keratin that look like pearls - so they're called keratin pearls.

一般来说，恶性肿瘤细胞形态各异且细胞核深染，伴有增大的核仁，还会产生珍珠样的异常角质——称作角化珠。