GnRH makes the nearby pituitary gland secrete two hormones of its own, called gonadotropins.

GnRH促使附近的垂体自身分泌两种激素，称为促性腺激素。

High prolactin levels inhibit hypothalamic GnRH production, therefore inhibiting ovulation and menstruation.

高泌乳素水平抑制下丘脑产生GnRH，从而抑制排卵和月经。

Normally, the hypothalamus, which is located at the base of the brain, secretes gonadotropin-releasing hormone, or GnRH.

正常情况下，位于脑基底部的下丘脑分泌促性腺激素释放激素，即GnRH。

The steady increase in estrogen makes the pituitary more responsive to the pulsatile action of hypothalamic GnRH.

雌激素的突然升高使得垂体对下丘脑脉冲式分泌的GnRH更加敏感。

Before puberty, the hypothalamus constantly secretes small amounts of a hormone called gonadotropin-releasing hormone, or GnRH.

青春期前下丘脑会持续地小剂量地分泌一种激素，叫作促性腺激素释放激素，即GnRH。

These include Kallmann syndrome, where GnRH producing neurons fail to migrate from the nose region to the hypothalamus during fetal development.

这包括Kallmann综合征，即制造GnRH的神经元在胚胎发育时未能从鼻区域迁移至下丘脑。

This causes low levels of GnRH, FSH, and LH, and as a consequence, low estrogen, so puberty either never starts or is incomplete.

这导致低水平的GnRH、FSH和LH，结果造成雌激素水平低，导致青春期发育不全甚至不发育。

The hypothalamus secretes gonadotropin-releasing hormone, or GnRH, which makes the nearby anterior pituitary gland release follicle-stimulating hormone, or FSH, and luteinizing hormone, or LH.

下丘脑分泌促性腺激素释放激素，即GnRH，刺激临近的垂体前叶释放卵泡刺激素（FSH）和黄体生成素（LH）。

That GnRH travels to the nearby pituitary, which secretes two hormones of its own - follicle stimulating hormone, or FSH, and luteinizing hormone, or LH.

GnRH作用于垂体，分泌两种激素：卵泡刺激素（FSH）和黄体生成素（LH）。

Next, there's functional hypothalamic amenorrhea, which is when there is a decrease in GnRH secretion, leading to low levels of LH, FSH, and estrogen.

其次是功能性下丘脑性闭经，即由于GnRH分泌下降导致LH、FSH和雌激素水平下降。

Once puberty hits, the hypothalamus starts to secrete GnRH in pulses, sometimes more and sometimes less, and pituitary FSH and LH make the ovarian follicles develop.

一旦到了青春期，下丘脑就会开始脉冲式地分泌促性腺激素释放激素，有时量多，有时量少。而垂体分泌的FSH和LH就会使卵巢滤泡成熟。

The amount of GnRH can be mapped out like a wave over time, and the frequency and amplitude of the waves of GnRH determine how much FSH and LH get produced by the pituitary.

GnRH的量随时间变化，描绘出来就像波浪一样，而它的频率和振幅，决定了垂体分泌FSH和LH的量。