| 单词 | replication |
| 例句 | Even if Linus was somewhere near the right structure, the odds seemed against his getting near the secret of gene replication. Double Helix 1968-02-27T00:00:00Z Even more exciting, this type of double helix suggested a replication scheme much more satisfactory than my briefly considered like-with-like pairing. Double Helix 1968-02-27T00:00:00Z Moss did his best to keep his mind on the intricacies of cell replication until four, when Mrs. Hernandez had to close things up. Anger Is a Gift 2018-05-22T00:00:00Z Instead, Francis had the feeling that DNA replication involved specific attractive forces between the flat surfaces of the bases. Double Helix 1968-02-27T00:00:00Z According to these historians, replication is a social artefact, not a natural fact. The Invention of Science 2015-09-17T00:00:00Z The simple truth is that replication of the Torricellian experiment was unproblematic; it follows that the sociologists of science are wrong. The Invention of Science 2015-09-17T00:00:00Z “With the same rapid replication, the same ability to spread through the air. And then we developed a vaccination for it. Just a temporary one, only lasts for forty-eight hours, but still.” Allegiant 2013-10-22T00:00:00Z His claims provoked a widespread concern with the replication of his experiments precisely because the viability of Aristotelian orthodoxy was now at stake. The Invention of Science 2015-09-17T00:00:00Z And, of course, as replication became the test, historical facts, which had once seemed so solid and reliable, came to seem increasingly fragile and tenuous. The Invention of Science 2015-09-17T00:00:00Z Thus, the essential trick of gene replication could come from the requirement that each base in the newly synthesized chain always hydrogen-bonds to an identical base. Double Helix 1968-02-27T00:00:00Z A smaller number of geneticists, however, balked at complementary replication. Double Helix 1968-02-27T00:00:00Z Mutations might occur during replication if the enzyme DNA polymerase makes a mistake. Cosmos 1980-01-01T00:00:00Z Princesse peered at this re-creation, not immediately recognizing herself, but then seeing in the face, the eyes, the breasts, a very true replication of her body. Krik? Krak! 2015-12-15T00:00:00Z DNA replication requires many more proteins than just DNA polymerase to unfold the twisted double helix and to ensure that the genetic information is copied accurately. The Gene 2016-06-02T00:00:00Z The tricky, unsolved thing is how to get the polymers to arrange in membranes and invent replication. The Lives of a Cell 1974-01-01T00:00:00Z The time of year being autumn, the spider had left egg cases in its web, preparing for its own cycle of replication. The Hot Zone 1994-01-01T00:00:00Z To Watson and Crick, the double-helix model of DNA—with two complementary “yin-yang” strands counterposed against each other—instantly suggested a mechanism for replication. The Gene 2016-06-02T00:00:00Z Inside is the first beautiful thing I’ve seen in the District 13 compound: a replication of a meadow, filled with real trees and flowering plants, and alive with hummingbirds. Mockingjay 2010-08-24T00:00:00Z During replication, DNA is, once again, copied using its image as a guide. The Gene 2016-06-02T00:00:00Z A wax replication of the duel depicted Hamilton being shot by Burr and several hidden accomplices from ambush. Founding Brothers: The Revolutionary Generation 2000-10-17T00:00:00Z And replication is an essential part of science: a discovery isn’t considered valid if others can’t repeat the work and get the same result. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z He lay awake, thinking about the needle jabbing into his thumb, thinking about Ebola starting its inevitable replication in his bloodstream. The Hot Zone 1994-01-01T00:00:00Z The mitochondria do not arise de novo in cells; they are always there, replicating on their own, independently of the replication of the cell. The Lives of a Cell 1974-01-01T00:00:00Z The issue of replication is central to a topic of foremost importance for any understanding of the Scientific Revolution: the demise of alchemy. The Invention of Science 2015-09-17T00:00:00Z Mutations occur when DNA is damaged by chemicals or X-rays, or when the DNA replication enzyme makes a spontaneous error in copying genes. The Gene 2016-06-02T00:00:00Z Under this scheme, gene replication starts with the separation of its two identical chains. Double Helix 1968-02-27T00:00:00Z So the whole notion of replication, in the view of those who argue in this way, is misleading, and there is nothing transparent about experimental knowledge. The Invention of Science 2015-09-17T00:00:00Z There can be no replication if there is not some form of publication, or, at least, communication. The Invention of Science 2015-09-17T00:00:00Z Jahn says the replication was very straightforward, and the results confirmed the original study’s findings. Saving psychology 2013-02-27T19:02:00Z The replication of a low-budget, earnestly progressive public TV broadcast is impeccable, abetted by Helen Mirren’s hilariously solemn introductions of the films. Review: ‘Documentary Now!’ Skewers Politicians and Food Fetishists 2016-09-13T04:00:00Z It’s the only sign that what’s at work here is homage, not replication. Playlist: Jessica Reedy?s Album, ?From the Heart? 2011-11-20T02:15:30Z “Discovery work, across the board, tends to be valued higher than doing confirmation or replication work.” Saving psychology 2013-02-27T19:02:00Z The replication of flight has been a dream of cinema for a very long time, at least since William Wellman’s “Wings” was honored at the first Academy Awards. Film: 3-D Abounds, but What?s the Frenzy Really About? 2010-05-08T02:49:00Z It turns replication into a form of rethinking about art past and present, and about how myths are made. Critic’s Notebook: Prada Foundation Remounts a 1969 Exhibition 2013-08-13T21:52:42Z Here are three examples of localized food projects successfully challenging the current system—all of which lend themselves to replication in other areas. COVID-19 has exposed the fragility of our food system — here’s how we can localize it 2021-02-04T05:00:00Z But decades later many who knew him still feel protective, and recent replications have unleashed, along with fond memories, skepticism and even rage. The Return of the Shadowman 2021-10-20T04:00:00Z S. Center Strip, 877-603-4386; www.harrahs.com Las Vegas is a city obsessed with replication--and we're not talking carbon copies and model airplanes. Las Vegas: Sights Beyond The Slots 2010-04-26T20:00:00Z As with their other nonalcoholic spirits, Lyre's two recently released tequila alternatives have the most accurate replication of the original liquor's flavor. The best nonalcoholic tequilas for Cinco de Mayo 2022-05-03T04:00:00Z “We will need more than a handful of patients cured of HIV to really understand the duration of follow-up needed and the likelihood of an unexpected late rebound in virus replication,” they write. Second person cleared of HIV remains free of virus one year on 2020-03-10T04:00:00Z The thrill of well-made tiny food isn’t in flawlessness, but in meticulous replication, beautiful in its ordinariness and imperfection. How a Teeny-Weeny Chef Became a Great Big Star 2019-08-15T04:00:00Z This is replication, one of the three functional mechanisms in Darwin’s theory. Sex’s feel-good evolution: Charles Darwin’s erotic shocker 2014-03-09T20:00:00Z But ultimately the Balen-Gucci looks also seemed more like an act of replication than an actual merging of the minds. Is Fashion Hacking the Future? Gucci Says Yes. 2021-04-16T04:00:00Z The techniques of printmaking and sculptural casting, with their complex choreographies of replication and mirror reversal, presence and absence, are everywhere in play. Review | Seeing Jasper Johns: A seminal artist’s career is celebrated and illuminated in two cities 2021-09-28T04:00:00Z After all, replication is not only a side effect of social media; it’s part of the point. People Are Stacking Too Many Stones 2018-12-02T05:00:00Z Indeed, the replication process is so precise, it brings new insights to the original, helping academics and tour guides alike. Your last chance to see Tutankhamun's tomb 2011-01-17T20:00:03Z What this “Frankenstein” isn’t is a replication of the source text with the addition of a lot of digital doohickeys like sound effects and illustrations that animate when tapped. Megaphone by Natalie Bakopoulos 2012-05-28T15:00:00Z “If it ain’t broke, don’t fix it” may be the unspoken motto of this band from Kettering, England, who forego innovation in favor of painstaking replication of 1970s psych rock. 12 Pop, Rock and Jazz Concerts to Check Out in N.Y.C. This Weekend 2020-01-16T05:00:00Z His writing stands out as startlingly original in a world that often feels crammed with literary replication. A cheater’s guide to everything 2012-09-10T19:49:00Z The replication of that enormous, international and sustained impact will be the job of the major studios in the near future, which in itself is nothing new. Film: Huge Film, Small Film: Big Stakes 2010-03-06T09:54:00Z “The replications are beautiful but they’re a little neat and contained to feel authentic,” she said. The Return of the Shadowman 2021-10-20T04:00:00Z But the ease of replication does present some questions for art professionals. 3-D Plastic Art for the Masses: Ready to Print 2011-05-13T12:32:37Z They can be rattled off easily: replication, variation, and selection. Sex’s feel-good evolution: Charles Darwin’s erotic shocker 2014-03-09T20:00:00Z Inday Fast-casual, meaning self-serve restaurants that are serious about the quality of the food yet readily lend themselves to replication, was a concept created by Chipotle more than 20 years ago. A Jams Revival (in Spirit) 2015-08-18T04:00:00Z “It is almost a perfect replication, from fabrics to carpeting, to furniture, to decorating,” Barry Williams, who played oldest brother Greg, said at a Television Critics Association meeting where networks preview upcoming shows. 'Brady Bunch' cast hangs wood paneling and beaded curtains to... 2019-07-25T04:00:00Z In the enveloping darkness, Mr. Barnett shed some of his clothing and laid it on the floor, creating a replication of himself: the ultimate echo. Dance Review: An Afternoon of Aggressive Hair and Forlorn Boots 2011-06-13T22:20:43Z A replication of Albert Street, they wrote on Reddit, included “Queensland Police uniforms, Aussie flags and period correct posters”. 'Famously the most Spanish city': The Crown mocked for lacklustre recreation of Australia 2020-11-22T05:00:00Z “That was something I hadn’t thought of trying before. It’s difficult to say this is exactly what the whiskey made in Ireland in 1865 tasted like, but I would guess it’s a pretty close replication.” The man who helped spark the cocktail movement — and keeps feeding it 2015-05-30T04:00:00Z The property, now a museum called the Martin House Complex, has been undergoing tens of millions of dollars in restoration, including replication of missing windows. Antiques: Hunting for Windows in a House by Frank Lloyd Wright 2011-07-07T21:49:42Z “Hollywood tends to copy itself. If somebody creates a successful show with a focus on native stories, and that show does really well, there’s this replication effect,” she told me. American University’s Laughter Lab is an incubator for marginalized comedians 2021-04-15T04:00:00Z And it’s not just mindless replication: as with any act of creation, the end result reflects a piece of whomever made it. The Many Lives of Roberto, a Soup 2020-01-14T05:00:00Z For the replication of DNA is the copying of information and the manufacture of proteins is a transfer of information – the sending of a message. James Gleick: 'Information poses as many challenges as opportunities' 2011-04-09T23:05:59Z Latin influences are sprouting up all over the world because simplicity combined with tastiness is a recipe for replication. What is the key to creating Latin American flavor? 2022-05-25T04:00:00Z That is because power seeks to reinforce itself through replication. Igniting Resistance, or Smashing It, on TV 2017-01-31T05:00:00Z Neo-Darwinism allows for hypertrophy, the phenomenon by which evolution overshoots its mark and produces some consequence not strictly useful to the ends of genetic replication, the human brain as case in point. Marilynne Robinson: Can science solve life's mysteries? 2010-06-04T23:06:00Z It’s certainly a coincidence that a city known for an industry that once thrived on its capacity for replication produced a cocktail spec that has now been rejiggered worldwide. The born-in-Detroit cocktail that has spawned countless variations 2016-04-24T04:00:00Z As the novelist Jacob Rubin wrote recently at Slate, in an appreciation of Dana Carvey’s Bush impression, a good impersonation “does not seem like a studied replication so much as an emotional communion.” Kate McKinnon’s Genius Hillary Impersonation 2015-04-13T04:00:00Z Last month in Bristol, as part of our nationwide programme of seminars, participants gathered to discuss the replication of portrait imagery in the media. The power of portraits: what more could you be doing with yours? 2013-04-11T13:38:18Z Taylor Swift released note-for-note replications of two old albums, allowing everybody a brief opportunity to get mad at an ex-boyfriend she had stopped dating a solid decade ago. Let’s Look Back on 2021, When We Couldn’t Stop Looking Back 2021-12-15T05:00:00Z You like your Neapolitan tailoring and your British tweeds and your Japanese commitment to faithful replication? Critical Shopper: The Armoury, From Hong Kong, Brings Men’s Clothing to TriBeCa 2014-01-29T20:58:08Z In an industry where success leads to replication, Emerson's cultivation of late-night should have expanded opportunities for other women in similar time slots … in theory, and a perfect world. Why women really don’t get to host late-night TV 2023-06-09T04:00:00Z He once acknowledged in an interview about his edible replications of food that he wasn’t always sure what was real and what wasn’t. Homaro Cantu, Chicago chef who blended food and science, dies at 38 2015-04-15T04:00:00Z His adaptation is neither a free-spirited reworking of Pynchon’s novel nor an obsessively dependent replication of it. Inherent Vice: Paul Thomas Anderson’s Nostalgia Trip 2015-01-09T05:00:00Z The neighborhood maps that Claremont-based Joe Zaldivar draws, copying spreads from the Yellow Pages, are also suffused with upbeat energy, his labor-intensive replications a kind of humble homage to place and its codified representations. The art of the developmentally disabled on its own terms, minus the lens of sympathy 2016-08-25T04:00:00Z One particularly nasty type of computer virus that relies on humans for replication, known as a “Trojan horse,” disguises itself as something useful or interesting in order to persuade individuals to download and spread it. How religious fundamentalism hijacks your brain, as explained by a neuroscientist 2018-09-10T04:00:00Z "It's almost impossible to publish a failure to replicate," said Mr. Simons, who is working to start a journal dedicated to replication studies. ArtsBeat: Lehrer Apologizes for Recycling Work, While New Yorker Says It Won't Happen Again 2012-06-20T20:07:37Z In the following decades, though, six replication studies in different cities found mixed effects; some even suggested that arrests encourage revenge against the victims. The Trouble with Crime Statistics 2020-01-09T05:00:00Z The standard fallback position that reciprocal altruism is just another trick by which the selfish gene ensures its own replication makes one wonder just what observation could threaten Raine's thesis. The Anatomy of Violence by Adrian Raine – review 2013-06-13T11:00:01Z Sickert subtitled some of his later works Echoes, and that's the definition of this picture: the replication of some distant original. The 10 best portraits of queens 2012-06-02T23:06:01Z As “mere” repetitions of the 1962 works, the retreads invoked the replication that powers consumer culture. When a Warhol for $225 Has More Heft Than One for $195 Million 2022-05-09T04:00:00Z His consciousness was loaded into a synthetic replication of his body at the end of Season 1 when it looked as if an inoperable brain abnormality was going to finish him off. "Star Trek: Picard" challenges us to consider that our icons change, yes even in franchises 2023-03-02T05:00:00Z The relationship between the two men seesawed over the years, especially after the replication of Nobu across the globe proceeded without Mr. Nieporent. Drew Nieporent May Be the Last Old-School Restaurateur Standing 2017-09-12T04:00:00Z The exhibition “Crucified Ukraine,” at a museum in the shadow of Kyiv’s stainless steel Motherland Monument, includes exacting replications of three underground shelters that housed 120 Ukrainians for more than a month this winter. The War in Ukraine Is the True Culture War 2022-07-15T04:00:00Z Spot-on in its replication of the indie rock of that era, it’s a wonder of texture and plotting. From Retro Yuck to Foodie Rap 2011-12-17T03:03:14Z Risen, though, believes Frank’s students’ work was not a real replication. Saving psychology 2013-02-27T19:02:00Z Today, as an adult, I still struggle to overcome the feelings that nearly killed me 20 years ago—and I live in fear of their replication, someday, in my daughter, or my son. “They ripped him apart”: Searching for answers in the suicide of bullied teen Jadin Bell 2013-09-08T11:00:00Z Because as written, Nicoletta Italian Kitchen is not ready for replication. Review | Nicoletta Italian Kitchen writes a recipe for expansion, but it needs some editing 2019-05-20T04:00:00Z Its design is one of replication and symmetry. These larger-than-life sculptures elevate the timeless fern, with obsessive botanical accuracy 2020-06-01T04:00:00Z He talks about the replication crisis, where researchers are unable to replicate results for long-accepted studies. Mr. CrossFit vs. Big Soda: A profane fitness guru’s wonky war with the soda industry 2018-06-03T04:00:00Z The combination of note-perfect musical replications and gripping visuals demands so much of your attention that it inevitably has an effect on the atmosphere. Kraftwerk at Tate Modern, night four: The Man Machine 2013-02-11T12:26:00Z What I mean by evolution is this idea of survival of the fittest and adaptation by replication or birth of offspring. Lee Cronin: 'Aliens could be made from iron' 2011-08-27T23:06:02Z Ever since Johns first introduced mirroring devices into his work in the mid-1970s, he has been preoccupied with a dynamic of replication and loss. Review | Seeing Jasper Johns: A seminal artist’s career is celebrated and illuminated in two cities 2021-09-28T04:00:00Z In “MJ,” the Michael Jackson replications and extrapolations by Christopher Wheeldon and others were exciting, sure, but quickly came to feel like a manic distraction from what could not be dramatized. Against All Odds, Broadway Rose to the Occasion. Mostly. 2022-05-18T04:00:00Z Cheap to produce, fast to shoot, exhausting to perform, edited into a sharded crossfire of reaction shots, reality TV proved itself an expedient, maneuverable vehicle optimized for speed, sensation and easy replication. Reality Stars Are Just Like Us 2022-02-12T05:00:00Z However, the film is reportedly not a direct replication of events. David O Russell's Abscam film to be named American Hustle 2013-04-16T11:34:02Z Even more bothersome in terms of content is the replication of the imagery of Christian nationalism that is central to the far right fascist movement. How Bruce Springsteen – and the left – can reclaim and cultivate a vocabulary of patriotism 2021-03-06T05:00:00Z “Are we talking about the replication of a recipe, or the replication of a philosophy?” The Perfect Menu. Now Change It. 2011-02-16T06:00:43Z Some works add their own wry touches by hinging on the friction between real and represented, or by playing on likeness, replication, mediation and originality. Enter the artist's Berlin studio — without leaving L.A. 2017-08-18T04:00:00Z For the first time in the annals of TV cookery shows, I conceived the notion that replication at home might be both possible and desirable. TV review: Panorama: Disabled or Faking it?; Britain's Oldest Stand Up; Simply Italian 2012-07-30T20:05:01Z The goal was a replication of “Bad Teacher,” a raunchy comedy from 2011 that paired the same stars and arrived to $32 million in sales. A Slow Weekend at Movie Theaters 2014-07-20T04:00:00Z In fact, there are three things that have to come together to produce free-living life-forms: the energy cycles that now power every living organism, a container cell and a replication process. Creation: The Origin of Life/The Future of Life by Adam Rutherford – review 2013-03-27T08:25:00Z "It's not a replication of the restaurant but I suppose it's an echo of how it was," said curator Nigel Walsh. Damien Hirst to serve up restaurant art 2011-07-06T15:22:34Z Throughout, replications of nature — feathers, wood, sky — appear as inducements to move closer to the real thing, and toward a state of enlightenment. When clothes are more than clothes: Phyllis Green's designs are journeys, hung on a hangar 2017-11-20T05:00:00Z So why do we choose to hide in our caves and settle for replication? Jack White: vinyl ambassador 2013-02-20T10:45:13Z And that’s deliberate, that it isn’t an exact replication of it. Q. and A.: Rockstar’s Dan Houser on Grand Theft Auto V 2012-11-10T01:05:01Z Copying Buddhist imagery, in this context, takes on added meaning, says Getty Research Institute chief curator Marcia Reed, as "replication is part of the artists' spiritual and artistic practice." 'Cave Temples of Dunhuang' at the Getty Museum wants to transport you to China's Silk Road 2016-03-18T04:00:00Z Kiernan’s direction, however, imbues the production with an unsettling feeling: The actresses mirror each other in ways that aren’t always exact replications but rather variations on themes. ‘The Same’ Review: Do You See What I See? 2022-02-23T05:00:00Z The composer’s program notes, explaining connections between the piece and the Meselson-Stahl DNA replication discovery, proved superfluous to enjoyment. Review | National Gallery’s East Garden Court doesn’t do any favors for Parker Quartet 2017-03-27T04:00:00Z What moves us, in turn, is the artist’s own attention to meticulous visual detail in her comics, charting the steps of the hair care process, a replication of her mother’s effort. Graphic Novels With Fresh Voices From the Margins 2019-08-29T04:00:00Z Mr. Rodgers and Mr. Williams both appear on the album’s first single, “Get Lucky,” an uncanny replication of the sparkling disco-funk of Mr. Rodgers’s band Chic. Daft Punk Gets Human With a New Album 2013-05-15T12:00:18Z Michael Frank, a developmental psychologist at Stanford University, ran across these issues as he and his students worked on the replications of several survey-type studies. Saving psychology 2013-02-27T19:02:00Z Other artists involved with handmade replications include Nate Lowman, who in three paintings appropriates dour photographs from newspapers and then painstakingly copies them by hand in black paint on raw canvas. Art Review | 'Haunted': ?Haunted?: Photos and Appropriation at Guggenheim 2010-04-01T22:49:00Z There are no chapter breaks to mark these time shifts, in keeping with the novel’s replication of the flow of memory. Karl Ove Knausgaard’s ‘My Struggle: Book 4’ 2015-04-23T04:00:00Z But it's replication that causes the most problems. Creation: The Origin of Life/The Future of Life by Adam Rutherford – review 2013-03-27T08:25:00Z A spinoff of British music competition "Pop Idol," which aired from 2001 to 2003, the American version's success led to replications of that format around the world, including Australian, Latin American and Indian "Idols." 'American Idol' to make comeback on ABC TV in 2018 2017-05-09T04:00:00Z The 10 prints in “The Land” are slightly larger and much darker; as a romantic, Ms. Mann was less interested in the precise replication of the landscapes than in her responses to them. Seeing the South Through Sally Mann’s Lens 2018-03-05T05:00:00Z It happens to me in eerie replication one day. Behind the scenes of Comic Relief’s Love Actually: Andrew Lincoln’s creepy cards return 2017-03-12T05:00:00Z Its replication of three Botticelli Venuses deeply ingrained in a solid brick wall was a statement, Patha declared, on women’s “strength and our lack of escape.” At Tacoma Art Museum: Camille Patha’s vivid ‘Punch of Color’ 2014-02-27T22:26:49Z But "Planet Earth" is great because it feels like a response to trends — punk, disco, Krautrock, Bowie — not a direct replication of what had already been done. "Planet Earth" at 40: The perfect debut single that boldly launched Duran Duran 2021-01-30T05:00:00Z The publication was published under the title 'Dynamics and durability of HIV-1 neutralization are determined by viral replication' in the journal Nature Medicine. Another step toward the HIV-1 vaccine: Dynamics of neutralizing antibodies 2023-11-14T05:00:00Z Across the board, the project revealed extremely high replicability rates of their social-behavioral findings, and no statistically significant evidence of decline over repeated replications. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z For the past decade, psychology has been in the midst of a replication crisis. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z Further replication is needed, and cross-cultural studies using non-Western participants are scarce. People Lie 1.08 Times a Day 2023-10-31T04:00:00Z Analyses of the circulating virus showed it had mutated to allow replication in the A. albopictus mosquitoes, which have a different range from its original host, A. aegypti. A chikungunya vaccine is nearing approval. Who will get it? 2023-10-29T04:00:00Z These can arise from replication errors, chemicals, or environmental factors. Psoriasis not caused by spontaneous mutations in skin cells 2023-10-26T04:00:00Z Several follow-up surveys in which naïve participants evaluated descriptions of both the new studies and those associated with previous replication projects, found no differences in their respective predictability. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z Now, one of the first systematic tests of these practices in psychology suggests they do indeed boost replication rates. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z At the highest dose used, the compound provided a largely effective shield against the virus, either preventing infection completely or limiting viral replication. Infecting volunteers with dengue virus shows experimental drug’s promise 2023-10-26T04:00:00Z "Phages have components of bacterial CRISPR-Cas systems in their own genomes. They use these as molecular mimics for their own benefit to silence the immune system of bacteria and allow phage replication," he says. Scientists uncover new way viruses fight back against bacteria 2023-10-18T04:00:00Z Even essential cell processes, such as replication, are used to the cancer's advantage. Brain tumor treatment by targeting TUG1, a gene that controls replication stress 2023-10-12T04:00:00Z Thus, the replication success of these studies was not due to them discovering obvious results that would necessarily be expected to replicate. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z Each of the four labs submitted four studies for replication. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z Concerns about the unauthorized replication of individuals’ likenesses have been around for years, focused largely on the use of AI to create “deep fake” imitations of politicians and A-listers. Senators draft policy aimed at deep fakes of Drake, Tom Hanks and noncelebrities 2023-10-12T04:00:00Z “A water-tight system where no more replication takes place in chickens is necessary,” says Herfst, who has traced how avian flu viruses can evolve to transmit between mammals. In ‘proof of concept,’ CRISPR-engineered chickens shrug off flu 2023-10-10T04:00:00Z To improve the conditions for cancer cells, the invasive cells hinder the natural process of DNA replication. Brain tumor treatment by targeting TUG1, a gene that controls replication stress 2023-10-12T04:00:00Z Rigor enhancing practices can lead to very high replication rates, but exactly identifying which practices work best will take further study. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z The original researchers communicated with one another only via a project manager to try to keep the replications as independent as possible, to reflect the usual conditions when researchers attempt to replicate another group’s work. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z For example, some Schlafen proteins interfere with the replication of viruses in humans. Preventing spread of parasitic DNA in our genomes 2023-10-02T04:00:00Z This can lead them to limit access to replication materials to maximize their chances of obtaining patent protection. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Further studies are needed to fully understand how metformin prevents long COVID, but the drug may work by blocking viral replication. A Common Diabetes Drug May Prevent Long COVID in Some People 2023-06-22T04:00:00Z "The major finding is that when you follow current best practices in conducting and replicating online social-behavioral studies, you can accomplish high and generally stable replication rates." Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z Across all 64 replications, 55 found the same effect as the original study—an 86% replication rate. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z Interferons are cytokines that bind to cells causing them to produce substances that inhibit viral replication. Fundamentals of Biology 2015-01-01T00:00:00Z Thus, while encouraging innovation, IP rights can also discourage sharing of research materials and exacerbate the replication crisis. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Understanding the mechanisms of DNA replication enabled scientists to develop laboratory techniques that are now used to identify genetic diseases, pinpoint individuals who were at a crime scene, and determine paternity. Concepts of Biology 2013-04-25T00:00:00Z Their study's replication findings were 97% the size of the original findings on average. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z In previous replication studies, scientists attempting to replicate other labs’ work found smaller effects than the original work. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z In two other papers investigated, the committee concluded that Pruitt failed to “keep complete and accurate records of their data in a manner that would allow for verification or replication.” University investigation found prominent spider biologist fabricated, falsified data 2023-05-11T04:00:00Z In short, the CAA establishes a private, controlled channel of communication for the transfer of replication materials between authors and replicators. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Cells on the path to cell division proceed through a series of precisely timed and carefully regulated stages of growth, DNA replication, and division that produce two genetically identical cells. Concepts of Biology 2013-04-25T00:00:00Z By comparison, prior replication projects observed replication findings that were roughly 50%. Social-behavioral findings can be highly replicable, six-year study by four labs suggests 2023-11-09T05:00:00Z In the new study, however, the researchers’ replications produced effects of similar size to those found by the original labs. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z “As artificial intelligence continues to mature, these capabilities grow exponentially more dangerous. AI can now create realistic, false images of people and voice replication,” Davis said. Senate talks terror prevention since Boston Marathon bombing 2023-04-26T04:00:00Z Under the CAA mechanism, when submitting a paper for publication, an author would execute an agreement with the journal, pledging to provide full access to replication materials upon demand by other researchers. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z One of the critical processes monitored by the cell-cycle checkpoint surveillance mechanism is the proper replication of DNA during the S phase. Concepts of Biology 2013-04-25T00:00:00Z The biomedical agency approved the transfer and went on to award Gilbert, a DNA replication expert who publishes in Science, Nature, and Cell, a new, $2.5 million grant last year. NIH rules are supposed to stop ‘pass the harasser.’ In one recent case, they appear to have failed 2023-04-23T04:00:00Z It’s the first replication attempt that has followed studies from their conception through to independent replication, says Brian Nosek, executive director of the Center for Open Science and one of the four lab directors. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z “If there is a harsh sentence against environmental activists, we are likely going to see replication of this across states.” Muddy clothes? ‘Cop City’ activists question police evidence 2023-03-23T04:00:00Z Science is cumulative, and replications build its comprehensive and credible body. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Figure 7.6 Meiosis and mitosis are both preceded by one round of DNA replication; however, meiosis includes two nuclear divisions. Concepts of Biology 2013-04-25T00:00:00Z Three seal samples had mutations that have been shown to improve viral replication or increase virulence in mammals. Scientists Investigate a Bird Flu Outbreak in Seals 2023-03-15T04:00:00Z The 16 findings used in this study were chosen very differently from past replication studies—they “are not randomly selected from, or representative of, a well-defined literature,” she says. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z But when the rats were exposed to the Alpha, Delta and Omicron variants of the SARS-CoV-2 coronavirus, researchers found evidence of robust viral replication in the animals’ noses, mouths, throats and lungs. The coronavirus has infected New York City's rats. Why that's bad news for people 2023-03-10T05:00:00Z Unfortunately, the scientific community has struggled with a “replication crisis” in recent decades, where scientists in fields from economics to physics find it hard to reproduce results from published studies. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Instead, they infect a host cell and use the host’s replication processes to produce progeny virus particles. Concepts of Biology 2013-04-25T00:00:00Z Marchal found that the plants mounted a vigorous immune response—the patches of self-destructing cells were visible to the naked eye—and experienced almost no viral replication, whereas leaves from control plants suffered from infection. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z The authors also checked whether their results looked different when they used other ways to define a successful replication. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z However, validating biomarkers takes extensive replication studies in multiple, large populations. Do no unconscious harm: Can ‘hidden’ prejudices in medicine be stamped out? 2023-03-02T05:00:00Z One of the major challenges driving the replication crisis is that scientists often do not share all information needed to replicate their work. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z They vary in their structure, their replication methods, and in their target hosts or even host cells. Concepts of Biology 2013-04-25T00:00:00Z Observation, testing and replication can and will build faster jets, better medicines or more capable AI. Commentary: Go ahead and major in English. You'll be fine! 2023-03-01T05:00:00Z Some of those methods put the replication rate as low as 71%. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z The Australian singer Nick Cave recently called ChatGPT an exercise in “replication as travesty” — and a song it wrote in his style “a grotesque mockery of what it is to be human.” He made a children’s book using AI. Then came the rage. 2023-01-19T05:00:00Z Access to research materials is especially crucial for the replication of computational studies, given the increasing utilization of computational methods and the data-reliant nature of such studies on large data sets. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z More recently, molecular analysis of viral replication cycles has further refined their classification. Concepts of Biology 2013-04-25T00:00:00Z "What ChatGPT is, in this instance, is replication as travesty," Cave wrote in his newsletter The Red Hand Files. Nick Cave criticises AI attempt to write Nick Cave lyrics: 'This song sucks' 2023-01-17T05:00:00Z More than a decade ago, in the early days of what has come to be known as the replication crisis, four behavioral scientists from different subdisciplines got to talking about the causes of the problem. Preregistering, transparency, and large samples boost psychology studies’ replication rate to nearly 90% 2023-11-08T05:00:00Z “Both of these will prevent virus replication, and their crucial function is not altered in XBB.1.5.” Why COVID’s XBB.1.5 ‘Kraken’ Variant Is So Contagious 2023-01-10T05:00:00Z In other cases, as the boundary between academic and applied research blurs, commercial considerations keep replication materials private to preserve the prospect of their commercialization. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Attachment is a requirement for viruses to later penetrate the cell membrane, inject the viral genome, and complete their replication inside the cell. Concepts of Biology 2013-04-25T00:00:00Z Xocova is an oral antiviral agent taken once daily for five days to suppress replication of the virus. Shionogi says Japan government to buy 1 million more COVID pill doses 2022-12-13T05:00:00Z The world would be faced with a replication of “Munich 1938” on a grand scale. Opinion | How to achieve peace in Ukraine 2022-12-09T05:00:00Z The space, in fact, looks ready for easy replication, which is probably the point. Review | Ghostburger, that pandemic pop-up, is now ready for its close-up 2022-11-28T05:00:00Z The NDA would prohibit the use of the replication materials delivered by the original authors for any purpose other than replication. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z Once inside the cell, the viral capsid is degraded and the viral nucleic acid is released, which then becomes available for replication and transcription. Concepts of Biology 2013-04-25T00:00:00Z In normal cells, continued rounds of replication shorten telomeres until they become so short that they eventually trigger the cell to stop replicating. How cancer cells can become immortal 2022-11-24T05:00:00Z A replicating animal virus might accumulate mutations that make it better at using that human cell as a replication factory, or better able to evade human defences. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z Antiviral medications act by gumming up a pathogen’s replication machinery. For some COVID patients, 'Paxlovid rebound' has nothing to do with Paxlovid 2022-11-14T05:00:00Z Faced with a replication crisis, we believe that replication agreements facilitated by journals can improve science. A Simple Replication Agreement Could Improve Trust in Science 2023-07-10T04:00:00Z By attacking the virus at different stages of its replication cycle, it is difficult for the virus to develop resistance to multiple drugs at the same time. Concepts of Biology 2013-04-25T00:00:00Z In contrast, tumor cells can maintain the lengths of their telomeres by activating an enzyme called telomerase that rebuilds telomeres during each replication. How cancer cells can become immortal 2022-11-24T05:00:00Z If we only get 50% of the expected replication, that tells us that the human version works for this virus, but it’s not ideal. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z You've never succumbed to the mixture of MS and viral replication, a combination I liken to the perfect storm on a cold, winter's night. The forgotten immunocompromised are shouting from the trenches 2022-11-13T05:00:00Z Researchers don’t know whether such replication is happening in people with Long Covid or whether their bodies harbor virus reservoirs that help drive symptoms. News at a glance: Earth’s top geological sites, cameras on sharks, and China’s space station 2022-11-02T04:00:00Z The interferons stimulate uninfected cells to produce compounds that interfere with viral replication. Concepts of Biology 2013-04-25T00:00:00Z Knowing that cancer use these genes in their replication and growth means that researchers could also block them and potentially stop telomeres from lengthening and make cancer cells mortal. How cancer cells can become immortal 2022-11-24T05:00:00Z And if we see no replication, that means that the virus can’t use the receptor yet. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z It’s all built for volume, ready for replication. Restaurant review: A very sad lunch at Seattle’s Sugo Hand Roll Bar 2022-11-03T04:00:00Z One source of change is its highly mutable RNA genome, allowing “drifts” during each round of viral replication. To thwart the next pandemic, ‘swientists’ hunt for flu viruses at U.S. hog shows 2022-10-26T04:00:00Z Their genomes contain either DNA or RNA, and they replicate using the replication proteins of a host cell. Concepts of Biology 2013-04-25T00:00:00Z For elephants, at least, part of the answer may be the gene commonly known as p53, which also helps humans and many other animals repair DNA damaged during replication. Why Elephants Don’t Get Cancer 2022-10-21T04:00:00Z “When they say they did a direct replication of our study, they did not,” Dr. Alloy, a professor of psychology at Temple University, said. Sadder but Wiser? Maybe Not. 2022-10-18T04:00:00Z It does so by inhibiting the virus’s replication inside the human body, the same process that has made H.I.V. treatments so effective. The power of Paxlovid 2022-10-07T04:00:00Z He added that because the Nova Scotia orchard has more of a research focus, it was designed with randomization, replication and other factors in mind, “to make their data more relevant.” How About Them Apples? Research Orchards Chart a Fruit’s Future. 2022-09-27T04:00:00Z During initiation, the DNA is made accessible to the proteins and enzymes involved in the replication process. Concepts of Biology 2013-04-25T00:00:00Z It works by pausing replication and then either initiating repair or causing cells to self-destruct if the damage is too extensive. Why Elephants Don’t Get Cancer 2022-10-21T04:00:00Z But he is confident that patient work of science, underpinned by painstaking replication, will sort the real promise of hydrides from the questionable claims. ‘Something is seriously wrong’: Room-temperature superconductivity study retracted 2022-09-26T04:00:00Z The new analysis suggests that more than 100 million years ago, an ancestor of this fern duplicated its whole genome—a replication error that is common in plants, Li says. Strange Tree Fern Has a Surprisingly Enormous Genome 2022-09-23T04:00:00Z So lambda turns on its replication genes, makes copies of itself and bursts out of the cell to look for more undamaged cells to infect. Viruses may be ‘watching’ you 2022-09-21T04:00:00Z It turns out that there are specific nucleotide sequences called origins of replication at which replication begins. Concepts of Biology 2013-04-25T00:00:00Z But if the proton does not make it back by the time the two DNA strands separate—the first step of DNA replication—the cytosine might bind to a different base, adenine, rather than guanine. Quantum Tunneling Makes DNA More Unstable 2022-09-21T04:00:00Z They often get duplicated during viral replication, which can help the virus in two ways. Will the monkeypox virus become more dangerous? 2022-09-15T04:00:00Z When random mistakes occur during chromosome replication, fertilized eggs can inherit cells with these errors and result in a condition called aneuploidy, which essentially means "the wrong number of chromosomes." Most human embryos naturally die after conception 2022-09-05T04:00:00Z “Of course a drug that stops virus replication in a 70 yr old will do the same in 60 yr old,” Dr. Jha wrote. Paxlovid Cuts Covid Deaths Among Older People, Israeli Study Finds 2022-08-30T04:00:00Z There are multiple origins of replication on the eukaryotic chromosome, such that replication can occur simultaneously from several places in the genome. Concepts of Biology 2013-04-25T00:00:00Z With the normal DNA bonding and structure altered, Elion successfully interrupted cell replication. Chemistry 2019-02-14T00:00:00Z Understanding the mechanisms of DNA replication enabled scientists to develop laboratory techniques that are now used to identify genetic diseases. Biology for AP Courses 2022-06-09T00:00:00Z Errors that occur during chromosomal replication are essentially random, which means development can be disrupted in different ways in different embryos. Most human embryos naturally die after conception 2022-09-05T04:00:00Z RNA viruses like SARS-CoV-2 are always mutating; every replication in a hosts' cells creates a moment for a chance mutation to emerge. Why BA.5 became the dominant COVID variant 2022-08-10T04:00:00Z While there are many similarities in the DNA replication process, these structural differences necessitate some differences in the DNA replication process in these two life forms. Concepts of Biology 2013-04-25T00:00:00Z This allows both strands to function as a template for replication. Chemistry 2019-02-14T00:00:00Z During this phase, preparations are made for division that include growth, duplication of most cellular contents, and replication of DNA. Biology for AP Courses 2022-06-09T00:00:00Z Paxlovid is an oral treatment that works by stopping virus replication. Opinion | Biden has tested positive again. That’s no reason to avoid Paxlovid. 2022-08-01T04:00:00Z A study from the University of California, San Diego, says the rebound might be due to a lack of exposure, meaning not enough of the drug is reaching infected cells to stop all viral replication. Biden stuck in White House until mid-week due to recurring positive tests 2022-08-01T04:00:00Z This is accomplished by the process of DNA replication. Concepts of Biology 2013-04-25T00:00:00Z The doctor called it an instance of Paxlovid rebound and said Mr. Biden will be tested regularly to detect any viral replication and avoid giving the virus to others. Trump uses Biden’s COVID-19 rebound to re-air complaints about 2020 election 2022-08-01T04:00:00Z In the S phase, DNA replication can proceed through the mechanisms that result in the formation of identical pairs of DNA molecules—sister chromatids—that are firmly attached to the centromeric region. Biology for AP Courses 2022-06-09T00:00:00Z Perhaps Paxlovid suppresses viral replication initially, but if it’s stopped prematurely, there might still be virus that could cause a recurrence. Opinion | Biden has tested positive again. That’s no reason to avoid Paxlovid. 2022-08-01T04:00:00Z So, the zombie infects, co-opts the replication machinery of active viruses like a parasite, and at a minimum, seems to not make the ongoing viral illness worse. How Zombies Can Help Prevent the Next Pandemic 2022-07-29T04:00:00Z The replication of DNA occurs during the synthesis phase, or S phase, of the cell cycle, before the cell enters mitosis or meiosis. Concepts of Biology 2013-04-25T00:00:00Z Researchers say it might have something to do with how the drug is metabolized in certain individuals and whether it reaches enough infected cells to stop all viral replication. Trump uses Biden’s COVID-19 rebound to re-air complaints about 2020 election 2022-08-01T04:00:00Z A mutation can be passed to daughter cells through DNA replication and cell division. Biology for AP Courses 2022-06-09T00:00:00Z “The president will increase his testing cadence, both to protect people around him and to assure early detection of any return of viral replication,” the doctor wrote. Biden tests negative for the virus and will reemerge in Rose Garden 2022-07-27T04:00:00Z But even bigger gaffes often occur, creating zombie genomes that lack the replication or packaging functions a virus needs for productive infection. How Zombies Can Help Prevent the Next Pandemic 2022-07-29T04:00:00Z How does the replication machinery know where on the DNA double helix to begin? Concepts of Biology 2013-04-25T00:00:00Z The reason for this, we discovered, was likely a result of disrupted DNA replication at the telomeres that leaves chromosomes even more susceptible to damage or mutations. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Figure 14.18 In mismatch repair, the incorrectly added base is detected after replication. Biology for AP Courses 2022-06-09T00:00:00Z The sooner a person takes Paxlovid, the more effective it will be in stopping virus replication and curbing the progression to severe disease. Opinion | Biden’s covid diagnosis is a teaching moment for the country 2022-07-21T04:00:00Z During replication, DNA strands separate, and two complementary strands are created—one from each matching the opposite. Miller & Levine Biology 2018-01-01T00:00:00Z Certain proteins bind to the origin of replication while an enzyme called helicase unwinds and opens up the DNA helix. Concepts of Biology 2013-04-25T00:00:00Z One example of how basic and applied science can work together to solve practical problems occurred after the discovery of DNA structure led to an understanding of the molecular mechanisms governing DNA replication. Environmental Biology 2018-09-06T00:00:00Z The leading strand is synthesized in the direction of the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z This replication is necessary to confirm the reliability of the study’s reported results. An Introduction to Geology 2017-01-01T00:00:00Z Telomerase adds short, repeated DNA sequences to telomeres during replication, and helps prevent the genes near the ends of chromosomes from getting lost or damaged during replication. Miller & Levine Biology 2018-01-01T00:00:00Z Two replication forks are formed at the origin of replication, and these get extended in both directions as replication proceeds. Concepts of Biology 2013-04-25T00:00:00Z During DNA replication, new copies of DNA are made, shortly before a cell divides to form new cells. Environmental Biology 2018-09-06T00:00:00Z The leading strand is synthesized in the direction of the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z Examples of proto-oncogene products include cell-surface receptors for growth factors, or cell-signaling molecules, two classes of molecules that can promote DNA replication and cell division. Anatomy and Physiology 2013-06-19T00:00:00Z DNA replication in prokaryotic cells starts from one point and continues in two directions until replication is complete. Miller & Levine Biology 2018-01-01T00:00:00Z Cells have mechanisms for repairing DNA when it becomes damaged or errors are made in replication. Concepts of Biology 2013-04-25T00:00:00Z One of the questions it prompts is: What does the replication do to the meaning of the image? Perspective | Monet’s towering obsession Analyze the advantages and disadvantages of cooperative behavior, including changes in the likelihood of replication of the individual and population genomes. Biology for AP Courses 2022-06-09T00:00:00Z The following section will explore the structure of the nucleus and its contents, as well as the process of DNA replication. Anatomy and Physiology 2013-06-19T00:00:00Z DNA replication results in an incorrect base roughly once in every 10 million bases. Miller & Levine Biology 2018-01-01T00:00:00Z Modified plasmids are usually reintroduced into a bacterial host for replication. Concepts of Biology 2013-04-25T00:00:00Z “What population does this replication serve? What are the political implications?” The Robot Guerrilla Campaign to Recreate the Elgin Marbles 2022-07-08T04:00:00Z Viruses infect all known cell types and use the host cell’s replication proteins and metabolic machinery to replicate. Biology for AP Courses 2022-06-09T00:00:00Z When replication is completed, two identical DNA molecules exist. Anatomy and Physiology 2013-06-19T00:00:00Z When DNA replication is complete, the cell divides by binary fission, which is a form of asexual reproduction. Miller & Levine Biology 2018-01-01T00:00:00Z Addition of an enzyme called DNA ligase, which takes part in DNA replication in cells, permanently joins the DNA fragments when the sticky ends come together. Concepts of Biology 2013-04-25T00:00:00Z Anthony Bordg, a mathematician at the University of Cambridge, worries that his field could face a “replication crisis” like that plaguing scientific research. Should Machines Replace Mathematicians? 2022-07-07T04:00:00Z For these viruses, attachment is a requirement for later penetration of the cell membrane, so they can complete their replication inside the cell. Biology for AP Courses 2022-06-09T00:00:00Z Once the two original strands are bound to their own, finished, complementary strands, DNA replication is stopped and the two new identical DNA molecules are complete. Anatomy and Physiology 2013-06-19T00:00:00Z S: DNA Replication DNA replication is the stage of the cell cycle that results in two complete sets of DNA ready to be divided between the daughter cells. Miller & Levine Biology 2018-01-01T00:00:00Z One strand, which is complementary to the parental DNA strand, is synthesized continuously toward the replication fork so the polymerase can add nucleotides in this direction. Concepts of Biology 2013-04-25T00:00:00Z They suspected the drug might prevent viral replication, which depends on the microtubule network to bring together the pieces of new viruses. Cancer Drug Greatly Reduces Deaths in Hospitalized Covid Patients 2022-07-06T04:00:00Z Viruses have simply evolved to make use of these molecules for their own replication. Biology for AP Courses 2022-06-09T00:00:00Z Mistakes made during DNA replication, such as the accidental addition of an inappropriate nucleotide, have the potential to render a gene dysfunctional or useless. Anatomy and Physiology 2013-06-19T00:00:00Z Plasmid DNA contains a signal for replication, but it also has a genetic marker that makes it possible to distinguish bacteria that carry the plasmid from those that don’t. Miller & Levine Biology 2018-01-01T00:00:00Z As a consequence, it is telomeres that are shortened with each round of DNA replication instead of genes. Concepts of Biology 2013-04-25T00:00:00Z This is when an object like this “comes alive,” says Edwell John, Jr., clan leader of the Tlingit Dakl’aweidí , who was involved in a separate replication project with the museum. How Indigenous Groups Are Using 3-D Technology to Preserve Ancient Practices 2022-06-29T04:00:00Z In DNA viruses, the viral DNA directs the host cell’s replication proteins to synthesize new copies of the viral genome and to transcribe and translate that genome into viral proteins. Biology for AP Courses 2022-06-09T00:00:00Z Transcription begins in a fashion somewhat like DNA replication, in that a region of DNA unwinds and the two strands separate, however, only that small portion of the DNA will be split apart. Anatomy and Physiology 2013-06-19T00:00:00Z DNA polymerase, or the main enzyme involved in DNA replication, joins nucleotides to synthesize a new complementary strand of DNA. Miller & Levine Biology 2018-01-01T00:00:00Z DNA replication has been extremely well-studied in prokaryotes, primarily because of the small size of the genome and large number of variants available. Concepts of Biology 2013-04-25T00:00:00Z Antivirals, on the other hand, don’t target the spike protein, but rather the virus’s “replication machinery,” Duke said. Can these drugs stop a COVID infection in its tracks? Seattle researchers are on the forefront of new treatments 2022-06-13T04:00:00Z The viral replication cycle can produce dramatic biochemical and structural changes in the host cell, which may cause cell damage. Biology for AP Courses 2022-06-09T00:00:00Z Like DNA replication, there are three stages to transcription: initiation, elongation, and termination. Anatomy and Physiology 2013-06-19T00:00:00Z Regulatory proteins bind at a single point on a chromosome, sparking the S phase and DNA replication. Miller & Levine Biology 2018-01-01T00:00:00Z After replication, each DNA has one parental or “old” strand, and one daughter or “new” strand. Concepts of Biology 2013-04-25T00:00:00Z You talked about that masculinization of a whole condition, but that's just a replication of the masculinization of the whole world. ADHD doesn't just affect young people — and it's not about technology 2022-06-05T04:00:00Z Once inside the cell, the viral capsid is degraded, and the viral nucleic acid is released, which then becomes available for replication and transcription. Biology for AP Courses 2022-06-09T00:00:00Z What would happen if cell division of a body cell took place without DNA replication, or when DNA replication was incomplete? Anatomy and Physiology 2013-06-19T00:00:00Z For example, when you studied DNA replication, you learned about the enzyme DNA polymerase. Miller & Levine Biology 2018-01-01T00:00:00Z Replication in eukaryotes starts at multiple origins of replication, while replication in prokaryotes starts from a single origin of replication. Concepts of Biology 2013-04-25T00:00:00Z Each art piece was designed by Santa Fe, New Mexico, artist Kevin Box, first through paper origami and later as a much larger metal replication. Origami exhibit combines nature with grand art sculptures 2022-06-04T04:00:00Z These drugs inhibit replication by reducing the activity of the enzyme without affecting the host’s metabolism. Biology for AP Courses 2022-06-09T00:00:00Z Briefly explain the similarities between transcription and DNA replication. Anatomy and Physiology 2013-06-19T00:00:00Z First, DNA is copied through a process called DNA replication, resulting in a complete set of the DNA for each new daughter cell. Miller & Levine Biology 2018-01-01T00:00:00Z The DNA is opened with enzymes, resulting in the formation of the replication fork. Concepts of Biology 2013-04-25T00:00:00Z Box said that each piece takes him about a year from conception in paper form to realization as a metal replication through Box Studios. Origami exhibit combines nature with grand art sculptures 2022-06-04T04:00:00Z Their genomes contain either DNA or RNA—never both—and they replicate using the replication proteins of a host cell. Biology for AP Courses 2022-06-09T00:00:00Z DNA replication is the copying of DNA that occurs before cell division can take place. Anatomy and Physiology 2013-06-19T00:00:00Z These “checkpoint proteins” assure that cell activities, like DNA replication or spindle fiber production, are completed before the next phase is triggered. Miller & Levine Biology 2018-01-01T00:00:00Z Once replication is completed, the RNA primers are replaced by DNA nucleotides and the DNA is sealed with DNA ligase. Concepts of Biology 2013-04-25T00:00:00Z It’s also ripe for replication across the Sierra Nevada, which has many shuttered sawmills and an abundance of burned trees, they said. Greenville was destroyed by wildfire. Can it be rebuilt to survive the next one? 2022-05-30T04:00:00Z The viral replication cycle cannot affect genetic material of the host cell. Biology for AP Courses 2022-06-09T00:00:00Z Figure 3.24 DNA Replication DNA replication faithfully duplicates the entire genome of the cell. Anatomy and Physiology 2013-06-19T00:00:00Z The protocells could then form around RNA, which could then provide information for replication to occur. Miller & Levine Biology 2018-01-01T00:00:00Z Viral replication within a living cell always produces changes in the cell, sometimes resulting in cell death and sometimes slowly killing the infected cells. Concepts of Biology 2013-04-25T00:00:00Z They reason that, in the future, detailed scans of patients could be used to create joint-perfect replications of their bodies, allowing tissue like tendons to be grown for surgeries in a human simulacra. Scientists grow cells on a robot skeleton (but don’t know what to do with them yet) 2022-05-26T04:00:00Z Why does the HIV virus use reverse transcriptase in the replication process? Biology for AP Courses 2022-06-09T00:00:00Z During DNA replication, a number of different enzymes work together to pull apart the two strands so each strand can be used as a template to synthesize new complementary strands. Anatomy and Physiology 2013-06-19T00:00:00Z Absent far more radical, and unlikely, changes, such as the replication in other states of Wisconsin’s law, public-sector unions may settle into what he calls “a new equilibrium.” Opinion | That time Alito overturned a long-standing precedent and — crickets 2022-05-11T04:00:00Z The viral DNA directs the host cell’s replication proteins to synthesize new copies of the viral genome and to transcribe and translate that genome into viral proteins. Concepts of Biology 2013-04-25T00:00:00Z “With persistent infection, it represents ongoing, active replication of the virus.” UK patient had COVID-19 for 505 days straight, study shows 2022-04-21T04:00:00Z However, the process of replication is more complex than their model’s simple description. Biology for AP Courses 2022-06-09T00:00:00Z The term for this mode of replication is “semiconservative,” because half of the original DNA molecule is conserved in each new DNA molecule. Anatomy and Physiology 2013-06-19T00:00:00Z The replication of these records across the network is part of what prevents an incorrect or fake transaction from being logged. EXPLAINER: How cryptocurrencies work (and how they don’t) 2022-04-20T04:00:00Z Most productive viral infections follow similar steps in the virus replication cycle: attachment, penetration, uncoating, replication, assembly, and release. Concepts of Biology 2013-04-25T00:00:00Z They haven’t tested it in humans yet, but in cells and mice they found sulforaphane was a promising weapon against severe disease because it interferes with virus replication. A broccoli a day keeps COVID (and colds) away? Researchers are looking into it 2022-03-28T04:00:00Z This model suggests that the two strands of the double helix separate during replication, and each strand serves as a template from which the new complementary strand is copied. Biology for AP Courses 2022-06-09T00:00:00Z As you might imagine, it is very important that DNA replication take place precisely so that new cells in the body contain the exact same genetic material as their parent cells. Anatomy and Physiology 2013-06-19T00:00:00Z “It is this organization’s most urgent and collective responsibility to stop this haunting replication of the agonies of children in the 20th century.” UN to vote on blaming Russia for Ukraine humanitarian crisis 2022-03-23T04:00:00Z The replication mechanism depends on the viral genome. Concepts of Biology 2013-04-25T00:00:00Z It reduced replication of a half dozen types of the virus by 50%. A broccoli a day keeps COVID (and colds) away? Researchers are looking into it 2022-03-28T04:00:00Z What was not clear was how the replication took place. Biology for AP Courses 2022-06-09T00:00:00Z Once the process of DNA replication is complete, the cell is ready to divide. Anatomy and Physiology 2013-06-19T00:00:00Z And if natural immune responses and therapeutic treatments are unsuccessful, this uncontrolled viral replication can lead to the creation of mutant strains. To prevent future variants, we must protect those most at risk 2022-03-20T04:00:00Z These drugs, including the reverse transcriptase inhibitor AZT, inhibit HIV replication by reducing the activity of the enzyme without affecting the host’s metabolism. Concepts of Biology 2013-04-25T00:00:00Z There is what he called “massive” replication and distribution in its systems, so wiping the cloud clean of everything, everywhere, would be a tall order. A Paranoid Person’s Guide to Preparing for Digital Danger 2022-03-05T05:00:00Z In conservative replication, the parental DNA remains together, and the newly formed daughter strands are together. Biology for AP Courses 2022-06-09T00:00:00Z Much like the processes of DNA replication and transcription, translation consists of three main stages: initiation, elongation, and termination. Anatomy and Physiology 2013-06-19T00:00:00Z Researchers have fingered other causes for cancer biology’s replication problem, such as variations in mouse colony microbiomes. Glowing tumor marker may interfere with cancer studies in mice, creating reproducibility problems 2022-02-17T05:00:00Z The last stage of viral replication is the release of the new virions into the host organism, where they are able to infect adjacent cells and repeat the replication cycle. Concepts of Biology 2013-04-25T00:00:00Z The process is a slower-evolving one—not because the virus doesn’t change but because the replication cycles can be quite long. Discovery of New HIV Variant Sends Warning for COVID Pandemic 2022-02-17T05:00:00Z This is the sole reason which causes defects in DNA replication. Biology for AP Courses 2022-06-09T00:00:00Z Therefore, after DNA replication but before cell division, each cell actually contains two copies of each chromosome. Anatomy and Physiology 2013-06-19T00:00:00Z If the fluorescent light shined more strongly and sooner in the replication cycling, it meant more virus was present. The Pandemic Set Off a Boom in Diagnostics 2022-02-16T05:00:00Z Babaian and colleagues performed their search by hunting for matches to the central core of the gene for RNA-dependent RNA polymerase, which is key to the replication of all RNA viruses. New dangers? Computers uncover 100,000 novel viruses in old genetic data 2022-01-26T05:00:00Z As Salon has previously reported, RNA viruses like SARS-CoV-2 are, of course, always mutating; every replication in a hosts' cells creates a moment for a chance mutation to emerge. How likely is it for omicron to mutate into something deadlier? 2022-01-20T05:00:00Z Replication in prokaryotes starts from a sequence of nucleotides on the chromosome called the origin of replication—the point at which the DNA opens up or unzips. Biology for AP Courses 2022-06-09T00:00:00Z Each chromosome in the homologous pair is also bound to an identical sister chromatid, which is produced by DNA replication, and results in the familiar “X” shape. Anatomy and Physiology 2013-06-19T00:00:00Z Reading the paper 80 years later, as a replication crisis in the sciences continues to unfold, Angyal’s humility takes on a refreshing flavor. How Disgust Explains Everything 2021-12-27T05:00:00Z Molnupiravir induces mutations in the virus’ genome during replication, which some panelists think could facilitate the emergence of new virus variants; others feared it could lead to cancer-causing mutations in patients. FDA greenlights Pfizer’s oral COVID-19 drug 2021-12-22T05:00:00Z Those survivors then pass those traits to the offspring viruses it creates through replication. There's a giant, mysterious gap in the omicron variant's family tree 2021-12-21T05:00:00Z DNA replication employs a large number of proteins and enzymes, each of which plays a critical role during the process. Biology for AP Courses 2022-06-09T00:00:00Z A molecule of messenger RNA that is complementary to a specific gene is synthesized in a process similar to DNA replication. Anatomy and Physiology 2013-06-19T00:00:00Z Even if it curbs its deadly ways and settles in for a long stay, its error-prone replication machinery is bound to keep generating mutations. Could humanity catch a break with Omicron? 2021-12-17T05:00:00Z The result has been a replication crisis in behavior science, with researchers unable to repeat the findings of many past studies, calling the original results into question. A Penny for Your Squats? 2021-12-08T05:00:00Z The problem is that the same compound that interferes in the replication of the virus’s genetic material can also be transformed into one that resembles a building block of DNA. Merck’s COVID pill might pose risks for pregnant women 2021-12-13T05:00:00Z How does the replication machinery know where to begin? Biology for AP Courses 2022-06-09T00:00:00Z Mutations can arise spontaneously from errors during DNA replication, or they can result from environmental insults such as radiation, certain viruses, or exposure to tobacco smoke or other toxic chemicals. Anatomy and Physiology 2013-06-19T00:00:00Z "If you get it, you may reduce viral replication. Why not try all these things?" Listerine rejects GOP Sen. Ron Johnson’s claim that mouthwash can prevent COVID 2021-12-09T05:00:00Z Indeed, vague protocols and uncooperative authors, among other problems, ultimately prevented RP:CB from completing replications for 30 of the 53 papers it had initially flagged, the team reports in two capstone papers in eLife. More than half of high-impact cancer lab studies could not be replicated in controversial analysis 2021-12-07T05:00:00Z Coronaviruses produce a host of proteins essential for their replication, and each could be a target of a new drug. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z It turns out that there are specific nucleotide sequences called origins of replication where replication begins. Biology for AP Courses 2022-06-09T00:00:00Z If DNA replication did not take place fully, or at all, the offspring cells would be missing some or all of the genome. Anatomy and Physiology 2013-06-19T00:00:00Z The typical replication period in a healthy person would be just a couple of weeks, instead of many months; fewer replications mean less opportunities for new mutations. The Variant Hunters: Inside South Africa’s Effort to Stanch Dangerous Mutations 2021-12-04T05:00:00Z Other replications yielded mixed results, and some were negative or inconclusive. More than half of high-impact cancer lab studies could not be replicated in controversial analysis 2021-12-07T05:00:00Z A key factor in viral fitness is its replication rate – or how quickly a virus can make more copies of itself. Will omicron – the new coronavirus variant of concern – be more contagious than delta? 2021-12-03T05:00:00Z The origin of replication is recognized by certain proteins that bind to this site. Biology for AP Courses 2022-06-09T00:00:00Z As was discussed earlier with NK cells, killing a virally infected cell before the virus can complete its replication cycle results in the production of no infectious particles. Anatomy and Physiology 2013-06-19T00:00:00Z Additionally, the letter states that HIV is human-specific, and macaques' have qualities that prevent HIV replication in their tissues, and they cannot develop AIDS. Fauci blasted by PETA for using monkeys in 'horrendous HIV experiments' 2021-12-02T05:00:00Z Overall, only 46% of 112 reported experimental effects met at least three of five criteria for replication, such as a change in the same direction—increased cancer cell growth or tumor shrinkage, for example. More than half of high-impact cancer lab studies could not be replicated in controversial analysis 2021-12-07T05:00:00Z This type of replication is based on the organisms’ movement, rather than growing and then shedding a new being as other animals and plants do, Kriegman said. Living robots made of frog cells can now reproduce, study says 2021-12-02T05:00:00Z Two replication forks are formed at the origin of replication and these get extended bi- directionally as replication proceeds. Biology for AP Courses 2022-06-09T00:00:00Z Treatment for the disease consists of drugs that target virally encoded proteins that are necessary for viral replication but are absent from normal human cells. Anatomy and Physiology 2013-06-19T00:00:00Z Instead, they weaken two proteins involved in the virus’s replication machinery. Merck’s Covid Treatment Pill Wins Blessing of F.D.A. Panel 2021-11-30T05:00:00Z In an ironic twist, however, different replication efforts don’t always produce the same results. More than half of high-impact cancer lab studies could not be replicated in controversial analysis 2021-12-07T05:00:00Z The researchers hope that the xenobots can help them better understand the process of replication — a fundamental property of life — and how to control it. Living robots made of frog cells can now reproduce, study says 2021-12-02T05:00:00Z Single-strand binding proteins coat the single strands of DNA near the replication fork to prevent the single-stranded DNA from winding back into a double helix. Biology for AP Courses 2022-06-09T00:00:00Z Interferons have activity in slowing viral replication and are used in the treatment of certain viral diseases, such as hepatitis B and C, but their ability to eliminate the virus completely is limited. Anatomy and Physiology 2013-06-19T00:00:00Z Two mutations are at a site the virus uses to pry its way into those cells and hijack them for its own replication. How bad will Omicron be? Scientists won't really know for months 2021-11-30T05:00:00Z But the pills, which interfere with viral replication, are designed to be taken as soon as possible after symptoms appear. As Antiviral Pills Arrive, Can Testing Keep Up? 2021-11-29T05:00:00Z “If you can stop the replication at several steps or with multiple drugs, you exponentially decrease your chance of the virus developing resistance,” she said. Biden administration to buy Pfizer antiviral pills for 10 million people, hoping to transform pandemic 2021-11-16T05:00:00Z The replication fork moves at the rate of 1000 nucleotides per second. Biology for AP Courses 2022-06-09T00:00:00Z The authors hypothesized that T cells halt SARS-CoV-2 by disabling a cluster of viral proteins called the replication transcription complex, which helps the virus to reproduce. How Do People Resist COVID Infections? 2021-11-14T05:00:00Z RNA viruses like SARS-CoV-2 are, of course, always mutating; every replication in a hosts' cells create a moment for a chance mutation to emerge. Why the coronavirus is unlikely to mutate into something deadlier 2021-11-09T05:00:00Z The Merck drug mimics the building blocks of ribonucleic acid, or RNA, causing viral replication to go haywire by creating mutations — so many that the viral genetic machinery fails. Opinion | The promise of a pill: New vistas appear in the fight against covid-19 2021-11-06T04:00:00Z “I think getting an oral pill that can inhibit viral replication — that can inhibit this virus — is going to be a real game changer,” former FDA commissioner Scott Gottlieb told CNN in October. Pfizer says its antiviral pill reduces hospitalizations and deaths from COVID-19 2021-11-05T04:00:00Z DNA polymerase can only extend in the 5' to 3' direction, which poses a slight problem at the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z The researchers also found that even T cells from blood samples collected before the pandemic could recognize SARS-CoV-2—and most strongly recognized the replication complex. How Do People Resist COVID Infections? 2021-11-14T05:00:00Z "This replication process is not a perfect process, meaning that while you're going through the replication process errors will be introduced." Why the coronavirus is unlikely to mutate into something deadlier 2021-11-09T05:00:00Z It functions at a stage before viral RNA replication. Opinion | The promise of a pill: New vistas appear in the fight against covid-19 2021-11-06T04:00:00Z The N protein is a central player in viral replication, with roles that include stabilizing and releasing the virus’ genetic material. Why is Delta so infectious? New lab tool spotlights little noticed mutation that speeds viral spread 2021-11-03T04:00:00Z The other strand, complementary to the 5' to 3' parental DNA, is extended away from the replication fork, in small fragments known as Okazaki fragments, each requiring a primer to start the synthesis. Biology for AP Courses 2022-06-09T00:00:00Z "One way of dealing with the problem is replication, it's not the only way," Lord Frost said. Brexit: European Court of Justice 'not the only NI Protocol problem' 2021-10-26T04:00:00Z Compared with traditional small molecules or antibodies that inhibit viral replication or cellular entry, nanotechnology offers drug developers a suite of measures that may complement antiviral measures. Nanotechnology Offers New Ways to Fight an Endless Pandemic 2021-10-15T04:00:00Z Once in the body, it causes virus replication to go haywire by creating mutations — so many that the viral genetic machinery collapses. Opinion | This pill to treat covid could go a long way to getting us back to some kind of normal 2021-10-12T04:00:00Z A new study has identified a compound that blocks dengue virus replication in test tube experiments and in mice, and it might one day be available as an easy-to-take pill. First drug for dengue, an excruciating disease, may be on the horizon 2021-10-06T04:00:00Z Topoisomerase prevents the over-winding of the DNA double helix ahead of the replication fork as the DNA is opening up; it does so by causing temporary nicks in the DNA helix and then resealing it. Biology for AP Courses 2022-06-09T00:00:00Z In that deal, there was "replication" where EU law was replaced by international law. Brexit: European Court of Justice 'not the only NI Protocol problem' 2021-10-26T04:00:00Z “The replication of findings using two very different methods gives us confidence that our survey findings indicate actual change,” Greenfield says. How Pandemic Life Mimicked Pioneer Times 2021-10-05T04:00:00Z The Robert W. Woodruff Foundation, for example, wrote in comments accompanying the report that it favors “passive strategies and low-cost index replication” that don’t require extensive use of outside asset managers. Women, minorities manage 17% of major foundations’ assets 2021-09-30T04:00:00Z Further lab work suggested JNJ-A07 blocks the functioning of the replication complex, an assembly of five proteins that interact to enable the dengue virus to copy itself inside cells. First drug for dengue, an excruciating disease, may be on the horizon 2021-10-06T04:00:00Z Single-strand binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. Biology for AP Courses 2022-06-09T00:00:00Z Not one of them has been just like the original, and it doesn’t matter — I gave up the quest for replication long ago because every rendition has been so good. A Holy-Grail, One-Pot Roast Chicken 2021-09-01T04:00:00Z Critics cautioned that, among other things, the Harvard pair only published a single result, without replication. Thanks to a bit of diamond smashing, practical superconductivity could be close to reality 2021-08-26T04:00:00Z Because small copy mistakes happen during every replication cycle, a huge variety of slightly different genomes quickly emerges. New SARS-CoV-2 variants have changed the pandemic. What will the virus do next? 2021-08-19T04:00:00Z One apparent drawback is that for optimal effect, the drug would have to be given within a few days of symptom onset, before viral replication kicks into high gear. First drug for dengue, an excruciating disease, may be on the horizon 2021-10-06T04:00:00Z Table 14.1 summarizes the enzymes involved in prokaryotic DNA replication and the functions of each. Biology for AP Courses 2022-06-09T00:00:00Z In the new study, the authors tracked papers in psychology journals, economics journals, and Science and Nature with documented failures of replication. Why Bad Science Is Sometimes More Appealing Than Good Science 2021-08-17T04:00:00Z In its complaints, Apple claimed that “Corellium’s business is based entirely on commercializing the illegal replication of the copyrighted operating system and applications that run on Apple’s iPhone, iPad, and other Apple devices.” Apple settles lawsuit against security startup Corellium 2021-08-11T04:00:00Z On one hand, immunity reduces the likelihood of people getting infected, and may hamper viral replication even when they are. New SARS-CoV-2 variants have changed the pandemic. What will the virus do next? 2021-08-19T04:00:00Z But in vaccinated people, the replication soon alerts the immune system to send blood-borne antibodies that neutralize the virus in the nose and throat, Leal says. What does the Delta variant have in store for the U.S? We asked coronavirus experts 2021-08-04T04:00:00Z Explain why errors in DNA replication are rare events in cells. Biology for AP Courses 2022-06-09T00:00:00Z In a sense, what happened in Libya after 2011 was not so much a revolution against Qaddafi as a replication of his methods on a local level. Qaddafi’s Son Is Alive. And He Wants to Take Libya Back. 2021-07-30T04:00:00Z The virus’s rapid spread may in part result from a fast replication rate. Why Do Variants Such as Delta Become Dominant? 2021-07-30T04:00:00Z Since they would be interested only in self-preservation and replication, not protecting humanity or following its orders, such sentient machines would clearly tear up Asimov's rulebook. Artificial intelligence wants you (and your job) 2021-07-27T04:00:00Z But what we’re aiming at with these drugs are also components of the virus that are critical for replication, which may not be subverted by variants. Fauci on COVID Drugs, Vaccines and Getting Back to Normal 2021-07-26T04:00:00Z Errors in DNA replication are rare events in a cell due to the presence of DNA ligase enzyme which fixes mistakes in the copying process. Biology for AP Courses 2022-06-09T00:00:00Z As refugees from St. Domingue arrived in the United States, bringing news of the successful revolt, white Southerners were alarmed, fearing replication of the events on the island. Opinion | We Owe Haiti a Debt We Can’t Repay 2021-07-21T04:00:00Z These measures save lives and are worthy of replication elsewhere. Opinion | Rhode Island is working to stem the tide of opioid deaths 2021-07-21T04:00:00Z By contrast, small molecules “target viral replication, which is a totally separate process from how their proteins interact with the immune system,” Bender Ignacio says. There Are Few Good COVID Antivirals, but That Could Be Changing 2021-07-15T04:00:00Z Anvisa added that the conditions it imposed included demonstrating the absence of replication in all batches sent to Brazil. Exclusive: European efforts to assess Russia’s Sputnik V vaccine stymied by data gaps 2021-07-13T04:00:00Z Polymerase I and II are responsible for proofreading and fixing mistakes in the copying process which explains why errors in DNA replication are rare. Biology for AP Courses 2022-06-09T00:00:00Z The reports were scrubbed of references to their format, and the team excluded any that reported replications, which are much less common in standard publications. Quality shines when scientists use publishing tactic known as registered reports, study finds 2021-06-24T04:00:00Z Indeed, a timely analysis last year showed convincingly that it is a product of genetic recombination, a natural feature of coronavirus replication and evolution. Perspective | We may never know where the virus came from. But evidence still suggests nature. 2021-06-03T04:00:00Z The viral replication machinery is “highly conserved,” meaning that it changes little over time or among different strains. There Are Few Good COVID Antivirals, but That Could Be Changing 2021-07-15T04:00:00Z This viral transcendence hasn’t just stopped at the replication of symbolic information though. Transcendence Happens All the Time 2021-06-05T04:00:00Z Errors in DNA replication are rare events in cells due to the action of DNA helicase. Biology for AP Courses 2022-06-09T00:00:00Z In a nutshell, the underlying story goes something like this: All organisms in nature are simply vessels for the replication of the selfish genes that control us. It’s time to consign the “selfish gene” to the history books 2021-05-30T04:00:00Z And when the researchers examined citations in papers published after the landmark replication projects, they found that the papers rarely acknowledged the failure to replicate, mentioning it only 12% of the time. Unreliable social science research gets more attention than solid studies 2021-05-21T04:00:00Z The drug, which interferes with viral replication, already is in use among transplant recipients and patients with HIV. How a common, often harmless virus called cytomegalovirus can damage a fetus 2021-05-14T04:00:00Z The device missed one positive case in each replication study. Forget throat swabs: Dutch company claims its breathalyzer can help sniff out COVID-19 2021-05-17T04:00:00Z There are multiple origins of replication on the eukaryotic chromosome; humans can have up to 100,000 origins of replication. Biology for AP Courses 2022-06-09T00:00:00Z Some scientists hailed it as a stellar example of research replication that cast doubt on extraordinary claims that should have received closer scrutiny from the start. Does ocean acidification alter fish behavior? Fraud allegations create a sea of doubt 2021-05-06T04:00:00Z The guideline that “extraordinary claims require extraordinary evidence” seems to soften when it comes to publication decisions, agrees Massey University computational biologist Thomas Pfeiffer, who studies replication issues, but was not involved with this work. Unreliable social science research gets more attention than solid studies 2021-05-21T04:00:00Z Lab test suggests the drug also reduces viral replication of the virus. Covid: Asthma drug 'speeds up recovery at home' 2021-04-12T04:00:00Z The post of the unedited photo of the "Keeping Up with the Kardashians" star in a bikini surprised the famous family's camp, who reportedly threatened legal action if replications of it weren't removed. Khloé Kardashian addresses leaked bikini photo, defends removing it from internet 2021-04-08T04:00:00Z The number of DNA polymerases in eukaryotes is much more than prokaryotes: 14 are known, of which five are known to have major roles during replication and have been well studied. Biology for AP Courses 2022-06-09T00:00:00Z Four “grandfathers in the field,” as Bruno calls them, criticized the replication in a paper in Biogeosciences. Does ocean acidification alter fish behavior? Fraud allegations create a sea of doubt 2021-05-06T04:00:00Z But a 2020 paper in the Proceedings of the National Academy of Sciences that looked at a different sample of papers found no relationship between citation and replication. Unreliable social science research gets more attention than solid studies 2021-05-21T04:00:00Z Many countries reintroduced border controls and began requiring quarantine for arriving travelers in recent months, as more contagious virus variants began spreading rapidly, a gloomy replication of the pandemic’s first wave. Europe’s Plan to Save Summer: A Travel Certificate 2021-03-17T04:00:00Z If this occurs just before DNA replication begins, the proton may get stuck on the “wrong side” of the strand, Slocombe said. Why Does DNA Spontaneously Mutate? Quantum Physics Might Explain 2021-03-17T04:00:00Z The essential steps of replication are the same as in prokaryotes. Biology for AP Courses 2022-06-09T00:00:00Z “I’ve become much more aware of all of this. I think I have become a better scientist,” he says, pointing to the automated analyses in the replication effort. Does ocean acidification alter fish behavior? Fraud allegations create a sea of doubt 2021-05-06T04:00:00Z But the original paper has been cited 1417 times—with more than 400 of those citations coming after the 2018 replication project. Unreliable social science research gets more attention than solid studies 2021-05-21T04:00:00Z They need a treatment to stop viral replication before the inflammatory cascade begins. How do you treat coronavirus? Here are physicians’ best strategies 2021-03-16T04:00:00Z Pollock said the adaptations he saw appeared to increase the virus’s rate of replication and protect it from disease-fighting antibodies: “You can’t really say the adaptation caused the deaths, but it’s certainly implied.” ‘An accelerated cauldron of evolution’: COVID-19 patients with cancer, HIV may play a role in emergence of variants 2021-03-12T05:00:00Z Replication forks are formed at each replication origin as the DNA unwinds. Biology for AP Courses 2022-06-09T00:00:00Z As Dixson asked in a tweet criticizing the replication effort, “Can one study claim to overturn 11 years of research?” Does ocean acidification alter fish behavior? Fraud allegations create a sea of doubt 2021-05-06T04:00:00Z A failed replication doesn’t necessarily mean the original finding was false, Serra-Garcia points out. Unreliable social science research gets more attention than solid studies 2021-05-21T04:00:00Z A network of tribal health aides provide frontline health care and critical testing, treatment and telemedicine links with faraway hospitals — a network being considered for replication in the Lower 48. Alaska’s Remote Villages Race Against Time and History 2021-03-07T05:00:00Z Since RNA replication is error prone, the virus in the vaccine could mutate to become dangerous again. How a debate over two competing vaccines gripped the medical community — in 1961 2021-02-21T05:00:00Z When the replication fork reaches the end of the linear chromosome, there is no place for a primer to be made for the DNA fragment to be copied at the end of the chromosome. Biology for AP Courses 2022-06-09T00:00:00Z Certain antiviral drugs such as remdesivir fight infections by serving as RNA decoys that gum up the viral replication process. The Coronavirus Is a Master of Mixing Its Genome, Worrying Scientists 2021-02-05T05:00:00Z "If you stop their replication by vaccinating widely ... not only are you going to protect individuals from getting disease, but you are going to prevent the emergence of variants." A new COVID vaccine is 66% effective — but how much does vaccine efficacy matter? 2021-02-07T05:00:00Z Some scientists speculate that a chronically ill patient provided more opportunities for replication and mutation, and the use of therapies such as convalescent plasma may have pressured the virus to evolve. The coronavirus is mutating—but what determines how quickly? 2021-02-05T05:00:00Z Mutations occur when the genetic code of an organism is not copied accurately during cell replication. Opinion | The coronavirus is mutating. Will our vaccines keep up? 2021-01-27T05:00:00Z DNA replication is a highly accurate process, but mistakes can occasionally occur, such as a DNA polymerase inserting a wrong base. Biology for AP Courses 2022-06-09T00:00:00Z Dr. Weller likens this approach to the cocktail therapies for H.I.V., which combine molecules that act on different aspects of the virus’s replication. The Coronavirus Is a Master of Mixing Its Genome, Worrying Scientists 2021-02-05T05:00:00Z “If you stop . . . the replication, viruses cannot mutate,” he said, adding that this is the reason “to vaccinate as many people as possible, as quickly as possible.” Coronavirus mutations add urgency to vaccination effort as experts warn of long battle ahead 2021-01-30T05:00:00Z Moore and her colleagues used “pseudoviruses” that infect cells using the same proteins as SARS-CoV-2, but are not capable of replication, to study the possibility of the virus dodging our immune systems. Why some coronavirus variants are more contagious—and how we can stop them 2021-01-27T05:00:00Z The variant, first detected in London and southeast England, may be 30 to 70 percent more transmissible, having evolved to bind more tightly to human cells, easing entry and replication, virologists have found. The U.K., facing a scary coronavirus strain, is running a high-stakes, real-world vaccine experiment 2021-01-26T05:00:00Z The thymine dimers distort the structure of the DNA double helix, and this may cause problems during DNA replication. Biology for AP Courses 2022-06-09T00:00:00Z In October, he notified the Pan American Health Organization that Venezuelan scientists discovered a molecule that nullifies the replication capacity of the new coronavirus. Maduro’s ‘miracle’ treatment for COVID-19 draws skeptics 2021-01-26T05:00:00Z SARS-CoV-2 is spreading uncontrollably around the world, and with every new replication, there’s a chance for mutations that could help the virus more effectively infect human hosts. COVID-19 will likely be with us forever. Here's how we'll live with it. 2021-01-22T05:00:00Z Science, which is already struggling with a replication crisis and other problems, cannot afford any further damage to its credibility. Premature Freakouts about Techno-Enhancement 2021-01-23T05:00:00Z “The less replication of the virus there is in the world, the fewer variants that are going to get generated.” Existing vaccines should work against new coronavirus variants—for now 2021-01-15T05:00:00Z Errors during DNA replication are not the only reason why mutations arise in DNA. Biology for AP Courses 2022-06-09T00:00:00Z It directs the EPA to prioritize studies that are publicly accessible for independent replication and to identify and make available the key studies behind significant regulatory actions. Greens rip EPA’s new ‘secret science’ rule as last-ditch attempt to hamstring Biden 2021-01-05T05:00:00Z Says Hendrich, “The etiologies are almost certainly multifactorial, but may involve overzealous immune responses, cardiopulmonary or systemic inflammation, vascular inflammation or clotting disorders, and direct damage from viral replication during acute illness.” The Problem of 'Long Haul' COVID 2020-12-29T05:00:00Z Compared to the existing therapy, which made use of immune stimulants called interferons, the new medications were more effective at suppressing viral replication and had fewer side effects. The Lifesaving Potential of Less-Than-Perfect Donor Kidneys 2020-12-17T05:00:00Z A 2019 PeerJ study found only 11 replication studies among nearly 40,000 ecology and evolution biology papers—and only four of these 11 studies managed to replicate the original finding. Psychology’s replication crisis inspires ecologists to push for more reliable research 2020-12-09T05:00:00Z During cell division, each daughter cell receives a copy of the DNA by a process known as DNA replication. Biology for AP Courses 2022-06-09T00:00:00Z He said the rule is not a “magic bullet” to solve the replication crisis but “an incremental step forward that takes a piece of this wider crisis in scientific integrity.” Greens rip EPA’s new ‘secret science’ rule as last-ditch attempt to hamstring Biden 2021-01-05T05:00:00Z It should require something: some effort, a brief moment of consideration between consumption and replication. Ban share buttons on social media | Commentary 2020-12-07T05:00:00Z Once inside, that RNA inserts itself into our cells’ own replication machinery and makes multiple copies of the virus. The vaccine miracle: how scientists waged the battle against Covid-19 2020-12-06T05:00:00Z When the virus tries to replicate, its enzymes incorporate the drug into the new genome, and the replication fails. For COVID Drugs, Months of Frantic Development Lead to Few Outright Successes 2020-11-13T05:00:00Z In conservative replication, the parental DNA is conserved, and the daughter DNA is newly synthesized. Biology for AP Courses 2022-06-09T00:00:00Z “Virus replication was completely blocked,” the authors wrote. Nasal Spray Prevents Covid Infection in Ferrets, Study Finds 2020-11-05T05:00:00Z That’s important, she says, because stopping viral replication in the nose can reduce the spread of infection among people who may be unaware they are sick. Will a small, long-shot U.S. company end up producing the best coronavirus vaccine? 2020-11-03T05:00:00Z Taken up by cells in our bodies, these RNA droplets instruct our cells’ replication machinery to make spike protein particles. The vaccine miracle: how scientists waged the battle against Covid-19 2020-12-06T05:00:00Z Psychology has taken some hits in recent years—most famously in the form of the “replication crisis.” Hypnosis Experts Cast Doubt on Famous Psychological Experiments 2020-10-21T04:00:00Z Helicase opens up the DNA double helix, resulting in the formation of the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z We use counselling and web tools to offer guidance on how to publish null, inconclusive, negative and other ‘nonstandard’ results, and award monetary research bonuses for the publication of negative results or replication studies. Institutions can retool for to make research more rigorous 2020-10-13T04:00:00Z In a memo, Dr. Sean Conley said the tests and other clinical and laboratory data “indicate a lack of detectable viral replication.” Trump tests negative for COVID-19 as he resumes campaigning in Florida 2020-10-12T04:00:00Z He said the negative tests and other clinical and laboratory data “indicate a lack of detectable viral replication.” Coronavirus live news: Trump tests negative for Covid; WHO reports record new global cases 2020-10-12T04:00:00Z Conley said the negative tests and other clinical and laboratory data “indicate a lack of detectable viral replication.” Trump tests negative for COVID-19, is not infectious: White House physician 2020-10-12T04:00:00Z Single-strand binding proteins bind to the single-stranded DNA near the replication fork to keep the fork open. Biology for AP Courses 2022-06-09T00:00:00Z He offered a digital replication of an oil painting, instead. Virginia student makes art for rapper Wale, of Nipsey Hussle 2020-10-11T04:00:00Z Viral replication: Symptoms start by the fifth day after infection for most people, and they include fever, cough, sore throat, fatigue, aches, pains, gastrointestinal issues, and loss of smell or taste. Trump’s COVID Case Could Be Entering a Crucial Stage 2020-10-09T04:00:00Z The drug mimics and then inserts itself into the virus, slowing down replication. Donald Trump rebuked for removing mask after leaving hospital – US politics live 2020-10-06T04:00:00Z “The monoclonal antibodies neutralize the virus and the remdesivir stops the viral replication,” he explained. Prospect of Trump’s early hospital discharge mystifies doctors 2020-10-04T04:00:00Z One strand is synthesized continuously in the direction of the replication fork; this is called the leading strand. Biology for AP Courses 2022-06-09T00:00:00Z It enters infected cells and blocks viral replication. Trump’s Covid Treatments Are Aimed at Preventing Severe Illness 2020-10-03T04:00:00Z The drug inhibits a viral enzyme used for replication of the pathogen. Here's what is known about President Trump’s COVID-19 treatment 2020-10-02T04:00:00Z Both studies highlight the critical role of a class of immune system proteins called interferons, so named because they interfere with the replication of viruses. One in Seven Dire COVID Cases May Result from a Faulty Immune Response 2020-09-30T04:00:00Z We are used to scientific advice that is based upon years of peer review and replication. Rival scientists divided over lockdowns may make a good story – but how accurate is it? | Stephen Buranyi 2020-09-29T04:00:00Z The other strand is synthesized in a direction away from the replication fork, in short stretches of DNA known as Okazaki fragments. Biology for AP Courses 2022-06-09T00:00:00Z The activity of viral infection and replication also persists longer in the guts of infants and children, he said. HK study finds COVID-19 stool tests may be more effective for infants 2020-09-07T04:00:00Z According to Brown, NUCs work by disrupting the viral replication process. Trio of antiviral drugs eyed as possible coronavirus treatment 2020-09-09T04:00:00Z Vitamin D may help reduce the spread of the virus given its ability to affect replication of viral cells and accelerate the clearance of the virus cells, the study found. Vitamin D deficiency may increase coronavirus risk, study says 2020-09-04T04:00:00Z Perhaps continuous immune pressure over years would select a small reservoir from which HIV replication would be less likely to reignite. HIV enters deep sleep in people who naturally control the virus 2020-08-25T04:00:00Z DNA replication is bidirectional and discontinuous; explain your understanding of those concepts. Biology for AP Courses 2022-06-09T00:00:00Z Such high replication might, in turn, contribute to severe disease. COVID-19 poses a riddle for the immune system 2020-08-16T04:00:00Z These immune proteins suppress viral replication early in disease. An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time 2020-07-28T04:00:00Z A new book by psychologist Stuart Ritchie presents case studies of replication failures and scientific misconduct from across scientific disciplines. Daily briefing: Quantum tunnelling takes time 2020-07-23T04:00:00Z It’s typically a software restriction that’s used to protect copyrighted works from unlawful distribution or replication. Quibi will finally let you screenshot, but it’s a little bit complicated 2020-07-23T04:00:00Z Replication on the lagging strand occurs in the direction away from the replication fork in short stretches of DNA called Okazaki fragments. Biology for AP Courses 2022-06-09T00:00:00Z For example, it would increase the possibility of correctly selecting individuals most in need of targeted early treatment, such as with therapies that directly inhibit viral replication. COVID-19 poses a riddle for the immune system 2020-08-16T04:00:00Z The response protects the body from infections by thwarting viral replication. An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time 2020-07-28T04:00:00Z Conducting a replication demands a theoretical commitment to the features that matter6. The best time to argue about what a replication means? Before you do it 2020-07-20T04:00:00Z Together with his overview of the replication crisis, this introduction would be useful for undergraduates or general readers. Fraud, bias, negligence and hype in the lab — a rogues’ gallery 2020-07-20T04:00:00Z The leading strand is synthesized in the direction of the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z A large replication study in 2004 confirmed none of the links between personality and mortality reported in Eysenck’s work, except for a modest association between cardiovascular disease and personality. Misconduct allegations push psychology hero off his pedestal 2020-07-15T04:00:00Z Key players in this two-part bat immune response are interferons, small signaling molecules that got their name because of their talent for interfering with virus replication. Scientists look at why bats carry viruses yet stay healthy 2020-07-12T04:00:00Z If researchers are willing to bet on a replication with wide variation in experimental details, that indicates their confidence that a phenomenon is generalizable and robust. The best time to argue about what a replication means? Before you do it 2020-07-20T04:00:00Z The reliance of DdCBE on DNA replication to implement the C–G to T–A conversion implies a theoretical maximum editing efficiency of 50%. Mitochondrial genome editing gets precise 2020-07-07T04:00:00Z Replication on the lagging strand occurs in the direction away from the replication fork in short stretches of DNA called Okazaki fragments. Biology for AP Courses 2022-06-09T00:00:00Z They trigger production of myriad proteins that attack the virus at every stage of invasion and replication, and they alert uninfected neighboring cells to prepare their own defenses. Can boosting interferons, the body's frontline virus fighters, beat COVID-19? 2020-07-08T04:00:00Z While identifying the kinases involved in SARS-CoV-2 replication, we were also able to learn a lot about how the virus changes our bodies. Coronavirus and cancer hijack the same parts in human cells to spread 2020-07-03T04:00:00Z A good-faith replication study matches its design to the original claims. The best time to argue about what a replication means? Before you do it 2020-07-20T04:00:00Z |
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