| 单词 | leukocyte |
| 例句 | Like minute scouts inspecting potential battle zones, leukocytes constantly scan cell walls for the little bits of stuff that HLAs have carried there, trying to spot anything that doesn’t belong. 1491 2005-10-10T00:00:00Z Outside, prowling, are white blood cells—leukocytes, to researchers. 1491 2005-10-10T00:00:00Z Pyrogen is released from leukocytes, adding fever to.hemorrhage, necrosis, and shock. The Lives of a Cell 1974-01-01T00:00:00Z Which means that unless an HLA lugs an invading virus to where the leukocyte can notice it, that part of the immune system cannot know it exists, let alone attack it. 1491 2005-10-10T00:00:00Z When a leukocyte spots an anomaly—a bit of virus, say—it destroys the infected or contaminated cell immediately. 1491 2005-10-10T00:00:00Z All people have multiple types of HLA, which means that they can bring almost every potential problem to the attention of their leukocytes. 1491 2005-10-10T00:00:00Z Complement is switched on at the right point in its sequence to release chemotactic signals, calling in leukocytes from everywhere. The Lives of a Cell 1974-01-01T00:00:00Z Only a few of us are plagued by boils, and we can blame a large part of the destruction of tissues on the zeal of our own leukocytes. The Lives of a Cell 1974-01-01T00:00:00Z Imagine having to worry about running leukocytes, keeping track, herding them here and there, listening for signals. The Lives of a Cell 1974-01-01T00:00:00Z The relevant set of genes is known as the human leukocyte antigen, or HLA. Did you get COVID but never feel sick? New study hints at why 2023-07-19T04:00:00Z The team then measured the expression of over 400 genes related to the immune system that are expressed by white blood cells, or leukocytes. How loneliness can compromise your physical health 2023-04-01T04:00:00Z When a bacterium is destroyed by phagocytic leukocytes, chemicals called endogenous pyrogens are released into the blood. Biology for AP Courses 2022-06-09T00:00:00Z Sometimes a mixture of dead leukocytes and fluid called pus accumulates in the wound. Anatomy and Physiology 2013-06-19T00:00:00Z In addition to genetic variants of the ACE2 receptor, scientists want to see whether differences in the human leukocyte antigen genes, which influence the immune system’s response to viruses and bacteria, affect disease severity. How sick will the coronavirus make you? The answer may be in your genes 2020-03-27T04:00:00Z Around the same time, calves were being stillborn with a condition called bovine leukocyte adhesion deficiency. From Two Bulls, 9 Million Dairy Cows 2019-06-20T04:00:00Z A match is made on the basis of human leukocyte antigen type, or tissue type, rather than on the basis of blood type. 'I call my stem cell donor my sister' 2019-06-08T04:00:00Z The population of leukocytes that arrives at an infection site depends on the nature of the infecting pathogen. Biology for AP Courses 2022-06-09T00:00:00Z Figure 4.17 Blood: A Fluid Connective Tissue Blood is a fluid connective tissue containing erythrocytes and various types of leukocytes that circulate in a liquid extracellular matrix. Anatomy and Physiology 2013-06-19T00:00:00Z When leukocytes then attach to the protein, the cells signal the brain to activate microglia. How Young Blood Rejuvenates an Old Animal's Brain 2019-05-14T04:00:00Z Other vials go for A-B-O blood type and more exacting tests to determine specific proteins, known as human leukocyte antigen, or HLA, typing that helps determine compatability between organ donor and recipient. ‘This room becomes sacred’ with organ donor’s body 2018-05-26T04:00:00Z Doctors look to see if the patient and potential donor share eight cell markers called human leukocyte antigens, or HLA. An LAPD officer needs a bone marrow transplant. His ethnicity limits his chances of getting one 2017-06-22T04:00:00Z A neutrophil is also a phagocytic leukocyte that engulfs and digests pathogens. Biology for AP Courses 2022-06-09T00:00:00Z Although one type of leukocyte called memory cells can survive for years, most erythrocytes, leukocytes, and platelets normally live only a few hours to a few weeks. Anatomy and Physiology 2013-06-19T00:00:00Z Patient leukocytes were collected by leukapheresis approximately 2 weeks after the series of autologous tumour vaccinations. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z This was passed through CF11 cellulose powder columns to remove leukocytes before parasite DNA extraction. Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution : Nature : Nature Research 2017-01-24T05:00:00Z The blood of potential donors is tested for six different types of tissue markers called human leukocyte antigens. Springfield man with autism donates kidney to brother 2015-12-12T05:00:00Z Neutrophils, shown in Figure 33.3, are the most abundant leukocytes of the immune system. Biology for AP Courses 2022-06-09T00:00:00Z Production of all leukocytes begins in the bone marrow under the influence of CSFs and interleukins. Anatomy and Physiology 2013-06-19T00:00:00Z To determine background staining, we used T cells from leukocyte reduction system cones from two or three healthy HLA-A2 donors from the Stanford Blood Center. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z First, the cells are purified using the CD34 surface marker from other leukocytes harvested from the bone marrow or mobilized peripheral blood of the recipient. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z This meant higher levels of three types of white blood cells that are integral to good immune function: leukocytes, monocytes and so-called "natural killer" cells. Binge Drinking May Weaken Immune System, Study Suggests 2015-01-05T05:00:00Z Neutrophils and eosinophils are particularly important leukocytes that engulf large pathogens, such as bacteria and fungi. Biology for AP Courses 2022-06-09T00:00:00Z Although leukocyte counts are high, the cells themselves are often nonfunctional, leaving the individual at increased risk for disease. Anatomy and Physiology 2013-06-19T00:00:00Z CD8 T cell lines specific for these phosphopeptides recognized and killed both leukemia cell lines and human leukocyte antigen–matched primary leukemia cells ex vivo. [Research Articles] MHC Class I-Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia 2013-09-18T18:55:08.247Z The precise mechanism of action of colchicine is uncertain, though the authors point to its high concentration in leukocytes. Colchicine Found Effective in Acute Pericarditis 2013-09-12T15:25:00Z We examined the patients’ plasma before and after treatment with gefitinib and documented changes in chemokines and leukocyte counts associated with the extent of rash or the presence of pruritus. [Research Articles] Genetic Ablation of Epidermal EGFR Reveals the Dynamic Origin of Adverse Effects of Anti-EGFR Therapy 2013-08-21T18:25:05.013Z A mast cell is a leukocyte that produces inflammatory molecules, such as histamine, in response to large pathogens. Biology for AP Courses 2022-06-09T00:00:00Z About 20–30 percent of all leukocytes are lymphocytes, which are critical to the body’s defense against specific threats. Anatomy and Physiology 2013-06-19T00:00:00Z Peeing on a ScanaFlo paddle allows the device to measure protein, glucose, leukocytes, nitrates, bilirubin, blood, urobilinogen, specific gravity, urine pH--and it checks for pregnancy. A Real-Life Tricorder Is Now Available for You to Buy and Scan Yourself 2013-05-22T14:45:00.243Z The drugs, known as leukocyte growth factors, will be the subject of a Friday meeting of an advisory committee to the U.S. Drugs from Amgen, others assessed by FDA as radiation treatments 2013-05-01T20:21:52Z Testing for a bone marrow match entails looking for genes in the human leukocyte antigen, or H.L.A., system, the part of the immune system that recognizes self and not self. ‘Half-Match’ Bone Marrow Transplants Cure Sickle Cell in Trial 2012-11-12T21:44:33Z A basophil is a leukocyte that, like a neutrophil, releases chemicals to stimulate the inflammatory response as illustrated in Figure 33.5. Biology for AP Courses 2022-06-09T00:00:00Z This is made up of uterine lining cells, erythrocytes, leukocytes, and other debris. Anatomy and Physiology 2013-06-19T00:00:00Z They are there seized upon by the leukocytes, which gather round the invaders in larger fashion, as if seemingly endowed with consciousness, so marvellous is the strategy. Pioneers of Evolution from Thales to Huxley With an Intermediate Chapter on the Causes of Arrest of the Movement 2012-04-26T02:00:14.960Z High-molecular-weight DNA was extracted from tumour tissue and leukocytes using standard procedures. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes 2012-03-28T21:50:58.107Z This increase in endothelial permeability results in increased leukocyte extravasation, which is a critical step in atherosclerotic plaque formation. [Research Articles] Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration 2011-12-07T19:55:09.007Z Eosinophils and basophils produce additional inflammatory mediators to recruit more leukocytes. Biology for AP Courses 2022-06-09T00:00:00Z Figure 18.2 Composition of Blood The cellular elements of blood include a vast number of erythrocytes and comparatively fewer leukocytes and platelets. Anatomy and Physiology 2013-06-19T00:00:00Z PD0325901 treatment induced a rapid and sustained reduction in leukocyte counts, enhanced erythropoiesis, prolonged mouse survival, and corrected the aberrant proliferation and differentiation of bone marrow progenitor cells. [Research Articles] A MEK Inhibitor Abrogates Myeloproliferative Disease in Kras Mutant Mice 2011-03-30T18:55:17.813Z They said a gene in the human leukocyte antigen region or HLA -- which contains a large number of genes related to immune system function -- was strongly linked with Parkinson's disease. Immune system gene linked with Parkinson's: study 2010-08-15T17:02:00Z HLA, the human leukocyte antigen, is one of the main factors in the immune system. 'Don't sniff at smelling a potential lover' 2010-07-10T23:05:00Z Macrophages, lymphocytes, and, occasionally, leukocytes can be found in some of the tissues. Biology for AP Courses 2022-06-09T00:00:00Z It floats at the top of the tube separated from the heaviest elements, the erythrocytes, by a buffy coat of leukocytes and platelets. Anatomy and Physiology 2013-06-19T00:00:00Z Their only real hope was a bone marrow transplant, preferably from a healthy sibling who shared the same type of HLA, or human leukocyte antigen, as Henry. Life in Henry's wake: Laurie Strongin won't let her son's death be a total loss 2010-03-25T04:00:00Z The man's body twitched and jerked as the Zark's protean cells passed through the adaptive process, and as the last leukocyte recoiled from tissue that had suddenly become normal, his consciousness returned. Insidekick The army of defense is made up of the white blood corpuscles or leukocytes and of connective tissue cells which separate themselves from the neighboring tissues. Nature Cure Another leukocyte that is found in the peripheral blood is the monocyte. Biology for AP Courses 2022-06-09T00:00:00Z Lymphocytes are the second most common type of leukocyte, accounting for about 20–30 percent of all leukocytes, and are essential for the immune response. Anatomy and Physiology 2013-06-19T00:00:00Z Once they have exited the capillaries, some leukocytes will take up fixed positions in lymphatic tissue, bone marrow, the spleen, the thymus, or other organs. Anatomy and Physiology 2013-06-19T00:00:00Z Granular leukocytes contain abundant granules within the cytoplasm. Anatomy and Physiology 2013-06-19T00:00:00Z The most common of all the leukocytes, neutrophils will normally comprise 50–70 percent of total leukocyte count. Anatomy and Physiology 2013-06-19T00:00:00Z Two additional leukocytes in the blood are eosinophils and basophils—both help to facilitate the inflammatory response. Biology for AP Courses 2022-06-09T00:00:00Z One of the more common adverse effects of cancer chemotherapy is the destruction of leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z Basophils are the least common leukocytes, typically comprising less than one percent of the total leukocyte count. Anatomy and Physiology 2013-06-19T00:00:00Z Unlike other leukocytes, memory cells live for many years. Anatomy and Physiology 2013-06-19T00:00:00Z They normally represent 2–8 percent of the total leukocyte count. Anatomy and Physiology 2013-06-19T00:00:00Z And although there is just one type of erythrocyte, there are many types of leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z Substances that can pass between cells include metabolic products, such as glucose, water, and small hydrophobic molecules like gases and hormones, as well as various leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z For leukocytes, the vascular network is simply a highway they travel and soon exit to reach their true destination. Anatomy and Physiology 2013-06-19T00:00:00Z In clinical medicine, the differential counts of the types and percentages of leukocytes present are often key indicators in making a diagnosis and selecting a treatment. Anatomy and Physiology 2013-06-19T00:00:00Z Some leukocytes, such as the eosinophil and neutrophil, are characterized as granular leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z While granules are not totally lacking in agranular leukocytes, they are far fewer and less obvious. Anatomy and Physiology 2013-06-19T00:00:00Z Of those that do enter, thousands are destroyed by phagocytic uterine leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z Agranular leukocytes include monocytes, which mature into macrophages that are phagocytic, and lymphocytes, which arise from the lymphoid stem cell line. Anatomy and Physiology 2013-06-19T00:00:00Z Eosinophils typically represent 2–4 percent of total leukocyte count. Anatomy and Physiology 2013-06-19T00:00:00Z Leukemia is a cancer involving an abundance of leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z In chronic leukemia, mature leukocytes accumulate and fail to die. Anatomy and Physiology 2013-06-19T00:00:00Z Although other plasma proteins are produced by the liver, immunoglobulins are produced by specialized leukocytes known as plasma cells. Anatomy and Physiology 2013-06-19T00:00:00Z In acute leukemia, there is an overproduction of young, immature leukocytes. Anatomy and Physiology 2013-06-19T00:00:00Z As in leukemia, the malignant leukocytes do not function properly, and the patient is vulnerable to infection. Anatomy and Physiology 2013-06-19T00:00:00Z Try constructing a simple table with each leukocyte type and then making a mark for each cell type you identify. Anatomy and Physiology 2013-06-19T00:00:00Z Blood is composed of formed elements—erythrocytes, leukocytes, and cell fragments called platelets—and a fluid extracellular matrix called plasma. Anatomy and Physiology 2013-06-19T00:00:00Z Cytokines are glycoproteins secreted by a wide variety of cells, including red bone marrow, leukocytes, macrophages, fibroblasts, and endothelial cells. Anatomy and Physiology 2013-06-19T00:00:00Z Through the process of hemopoiesis, the formed elements of blood are continually produced, replacing the relatively short- lived erythrocytes, leukocytes, and platelets. Anatomy and Physiology 2013-06-19T00:00:00Z The most abundant leukocytes are the neutrophils, which are first responders to infections, especially with bacteria. Anatomy and Physiology 2013-06-19T00:00:00Z Try constructing a simple table with each leukocyte type and then making a mark for each cell type you identify. Anatomy and Physiology 2013-06-19T00:00:00Z It is produced by specialized leukocytes called plasma cells. Anatomy and Physiology 2013-06-19T00:00:00Z Although leukocytes typically leave the blood vessels to perform their defensive functions, movement of erythrocytes from the blood vessels is abnormal. Anatomy and Physiology 2013-06-19T00:00:00Z Before the treatment, this patient was likely to have had increased activity of which leukocyte? Anatomy and Physiology 2013-06-19T00:00:00Z Moreover, circulating triglycerides and cholesterol can seep between the damaged lining cells and become trapped within the artery wall, where they are frequently joined by leukocytes, calcium, and cellular debris. Anatomy and Physiology 2013-06-19T00:00:00Z The presence of leukocytes may indicate a urinary tract infection. Anatomy and Physiology 2013-06-19T00:00:00Z The buffy coat is the portion of blood that is made up of its leukocytes and platelets. Anatomy and Physiology 2013-06-19T00:00:00Z One of the most distinctive characteristics of leukocytes is their movement. Anatomy and Physiology 2013-06-19T00:00:00Z A burn is especially likely to increase the proliferation of leukocytes in order to ward off infection, a significant risk when the barrier function of the skin is destroyed. Anatomy and Physiology 2013-06-19T00:00:00Z There is a chance to review each of the leukocytes individually after you have attempted to identify them from the first two blood smears. Anatomy and Physiology 2013-06-19T00:00:00Z While leukocytes and platelets are normally a small component of the formed elements, there are some rare conditions in which severe overproduction can impact viscosity as well. Anatomy and Physiology 2013-06-19T00:00:00Z |
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