| 单词 | endogenous |
| 例句 | Yet the mascot's Icarian fall hints at something endogenous: the coiled contempt that many nationalist Chinese are ready to spring at the merest whiff of waywardness. The rise and fall of Bing Dwen Dwen, Beijing's insidious Olympics mascot 2022-02-20T05:00:00Z Some people may be predisposed toward substance abuse by virtue of a systemic enzyme imbalance that results in pathologically low levels of endogenous cannabinoids. Pot: Not just for losers! 2012-08-15T11:44:00Z But then I also felt this endogenous, strangely insistent feeling that I did have worth. Misery and Megalomania: How David Adjmi Became a Playwright 2020-06-24T04:00:00Z Accumulating evidence indicates that pain resolution after tissue damage or inflammation is not passive, but rather an active process that involves endogenous pain resolution mechanisms. Disturbances in sensory neurons may alter transient pain into chronic pain 2023-11-08T05:00:00Z However, few studies have focused on the endogenous content of polysulfide in broccoli sprouts. Small but mighty: The hidden power of broccoli sprouts 2023-10-24T04:00:00Z Additionally, monkeys are thought to be immune to endogenous pig viruses. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z It's possible the brain uses its own endogenous DMT as a tool for change – as when forming dendritic spines on neurons – to encode pivotal mental states. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z We have endogenous opioid peptides in our bodies, but we don't pick up cute little bottles of morphine at Target. Immune boost or over-the-counter poison? Why your "health" supplements may do more harm than good 2023-08-12T04:00:00Z “China’s development has a strong endogenous momentum and inevitable historical logic, and it is impossible to try to transform China, and it is even more impossible to encircle and contain China,” Mr. Wang said. ‘Impossible’ to transform China, Kissinger told on Beijing visit 2023-07-19T04:00:00Z "An endocrine disruptor is a chemical that impacts the body's endogenous natural hormone function. And by impact, it could be increases, slows, or interferes with in various ways," Swan said. Even BPA-free plastic particles can mess with your sex hormones, study finds 2023-04-28T04:00:00Z “The power of any single speakership is endogenous,” he said. Speaker McCarthy: 100 days in power and a tough road ahead 2023-04-15T04:00:00Z "It turned out that the antibodies are recognising remnants of what's termed endogenous retroviruses," Prof Julian Downward, an associate research director at the Francis Crick Institute, told me. Million-year-old viruses help fight cancer, say scientists 2023-04-14T04:00:00Z As her court filing indicated, she "has not experienced and will not experience endogenous puberty." Trans athlete case exposes how anti-trans arguments contradict each other 2023-04-10T04:00:00Z But when it is artificially added to processed foods, it is seen at levels “1,000 fold higher than endogenous levels,” the researchers wrote. Artificial sweetener linked to higher heart attack risk, study says 2023-02-28T05:00:00Z HERVs, or human endogenous retroviruses, make up around 8% of the human genome, left behind as a result of infections that humanity's primate ancestors suffered millions of years ago. Humans are 8% virus – how ancient viral DNA in your genome plays a role in disease and development 2022-11-03T04:00:00Z HERVs, or human endogenous retroviruses, make up around 8% of the human genome, left behind as a result of infections that humanity’s primate ancestors suffered millions of years ago. How the Ancient Viral DNA in Our Genome Affects Disease and Development 2022-10-19T04:00:00Z When a bacterium is destroyed by phagocytic leukocytes, chemicals called endogenous pyrogens are released into the blood. Biology for AP Courses 2022-06-09T00:00:00Z Inside, the fluid that is circulating is actually a one-to-one mixture of the animal’s endogenous blood and our perfusate. How Scientists Revived Dead Pigs’ Organs, and What the Feat Means for Transplants 2022-08-10T04:00:00Z This acts as a substitute for endogenous neural stimulation, stimulating the muscle to contract and preventing the loss of proteins that occurs with a lack of use. Anatomy and Physiology 2013-06-19T00:00:00Z Animals form bonds through a number of chemical messengers acting in the brain to regulate social connection, such as oxytocin, vasopressin, glucocorticoids, endogenous opioids, and hormones, including androgens and estrogens. How catfishers exploit basic human neuroscience 2021-05-31T04:00:00Z There are around 30 different kinds of human endogenous retroviruses in people today, amounting to over 60,000 proviruses in the human genome. How the Ancient Viral DNA in Our Genome Affects Disease and Development 2022-10-19T04:00:00Z First of all, an endocrine disruptor is a chemical that impacts the body's endogenous natural hormone function. How plastics are making us infertile — and could even lead to human extinction 2021-04-04T04:00:00Z How these viral genes became part of the human genome, and to what purposes they have become adapted, are aspects of a remarkable story that begins with the concept of human endogenous retroviruses. How viruses shape our world 2021-01-14T05:00:00Z A chemical that the body produces to interact with those receptors is called an endogenous chemical, whereas a chemical introduced to the system from outside is an exogenous chemical. Anatomy and Physiology 2013-06-19T00:00:00Z You discuss what you call "endogenous" or "exogenous" cues as being important in interacting with the internet. Remember when the internet was supposed to be transparent and democratic? There's still hope 2020-07-18T04:00:00Z Whether the genetic remnants of human endogenous retroviruses can cause disease in people is still under study. How the Ancient Viral DNA in Our Genome Affects Disease and Development 2022-10-19T04:00:00Z These results suggest that astrocytes themselves, or cells in their environment, respond to the loss of endogenous dopamine-releasing neurons by expressing factors that promote the conversion of astrocytes to iDA neurons. Method to combat Parkinson’s disease by astrocyte-to-neuron conversion 2020-06-23T04:00:00Z The first gene of this sort from an endogenous retrovirus eventually was replaced by others that were similar but better suited for the role. How viruses shape our world 2021-01-14T05:00:00Z These drugs affect the autonomic system by mimicking or interfering with the endogenous agents or their receptors. Anatomy and Physiology 2013-06-19T00:00:00Z "Specific DNA staining is only observed inside the isolated cells, suggesting endogenous nuclear material survived fossilization," the researchers wrote in the study's abstract. Traces of DNA found in fossilized dinosaur skull, scientists claim 2020-03-03T05:00:00Z Similarly, mice, cats and sheep also found a way to use endogenous retroviruses to protect themselves against the original ancient virus that created them. How the Ancient Viral DNA in Our Genome Affects Disease and Development 2022-10-19T04:00:00Z His argument goes as follows: even in the absence of all self-perception mediated by the sense organs, we would still experience our own endogenous, felt volition. Yes, Free Will Exists 2020-02-05T05:00:00Z When retroviruses become part of an animal’s inherited DNA, they are called endogenous and eventually they no longer cause the kind of original infection they once did. A Virus in Koala DNA Shows Evolution in Action 2019-10-10T04:00:00Z This dense bone contains a high concentration of endogenous DNA. Use ancient remains more wisely 2019-08-27T04:00:00Z "It is not compatible with the science behind the issues and greatly overestimates the role of endogenous testosterone," he said. Testosterone athlete rule 'unscientific' 2019-03-20T04:00:00Z Romer, of New York University’s Stern School of Business, is best known for his work on endogenous growth, a theory rooted in investing in knowledge and human capital. U.S. economists win Nobel for work on climate change, innovation 2018-10-08T04:00:00Z His work on endogenous growth theory is not universally admired. Economics of climate change, innovation win Nobel Prize for U.S. duo 2018-10-08T04:00:00Z Dr. Theurkauf and his colleagues focused their work on snippets of RNA called piRNAs, which turn off endogenous retroviruses and keep them from replicating and jumping from spot to spot. A Virus in Koala DNA Shows Evolution in Action 2019-10-10T04:00:00Z Second, the neutral rate is endogenous to economic policy. Opinion | The Fault Lies in R-Star and in Ourselves 2018-09-25T04:00:00Z “We have no indication whatsoever that an endogenous disease or infection or some sort of metabolic disease can cause these types of symptoms,” said the hospital’s chairman, Karl Max Einhäupl. Poisoning ‘highly plausible’ in Pussy Riot case, German doctors say 2018-09-18T04:00:00Z Besides, it’s fun to trigger each other’s neuropeptide called oxytocin, our endogenous “love drug”, evoked when we cooperate, attach, affiliate and, yeah, make whoopee. Blissed out: the 13 steps to becoming happy 2018-09-10T04:00:00Z To use economics terminology, are the dynamics of success endogenous — driven by the fluctuating inspiration of the creator, say — or exogenous, produced by the vicissitudes of the marketplace? From artists to scientists, anyone can have a successful streak at any time 2018-07-10T04:00:00Z “They are not simply selfish, parasitic elements. They are endogenous to our beings, and we would not be able to do without them.” Don’t call it junk—This ‘jumping’ gene may be why you made it past an embryo 2018-06-21T04:00:00Z Those have been supplemented by more sophisticated carbon-isotope tests that are able to distinguish endogenous from exogenous steroids. The Scientific American Guide to Cheating in the Olympics 2017-12-05T05:00:00Z Other drugs that aim to reduce metabolic stress do so by mimicking endogenous hormones. Drug development: Sprint finish Now research suggests these endogenous opioids also play another role: helping regulate the body's energy balance. Even Unpalatable Foods Taste Good to the Brain 2017-11-21T05:00:00Z “We are witnessing a new bout of isolated actions, 11 since the beginning of the year, which supports the idea of an increasing endogenous threat,” he told franceinfo radio. France frets over 'internal' threat two years after Paris attacks 2017-11-12T05:00:00Z Some endogenous retroviruses offer protection against other viruses, for example. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z “Tunisia is becoming a kind of endogenous model of progress,” she said. Opinion | The Next Arab Spring? Women’s Rights. 2017-10-01T04:00:00Z Another is that the graft may bring with it novel infections, caused by what are known as endogenous retroviruses. Gene editing may make pigs into organ donors for people 2017-08-09T04:00:00Z Surprisingly, their brains released even more of the endogenous opioids after they ate a far less enticing—but nutritionally similar—liquid meal of what Nummenmaa called “nutritional goo.” Even Unpalatable Foods Taste Good to the Brain 2017-11-21T05:00:00Z “We are witnessing a new bout of isolated actions, 11 since the beginning of the year, which supports the idea of an increasing endogenous threat,” he told franceinfo radio. France frets over 'internal' threat two years after Paris attacks 2017-11-12T05:00:00Z Five years ago, the French biologist Odile Heidmann and her colleagues went on a search for more endogenous retroviruses in the human genome. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z Tests identified 25 Pervs - porcine endogenous retroviruses - hidden in the pig's genetic code. GM pigs take step to being organ donors - BBC News 2017-08-10T04:00:00Z The other problem is the risk for infection: the pig genome is riddled with infectious agents called porcine endogenous retroviruses, or PERVs. How turning off viruses in piglets could make their organs safer for people 2017-08-10T04:00:00Z This replication was dependent on how well the feline cells were able to squelch the endogenous viruses in the genome through a silencing process called methylation16. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Mutational signatures have been extensively catalogued across a broad spectrum of cancerous tissues, and for many of these, underlying exogenous and endogenous processes have been described. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z The early embryo is a hotbed of activity for endogenous retroviruses, recent studies have shown. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z While nuclear DNA from the HST fossil would tell us even more, unfortunately the endogenous Neanderthal DNA in the fossil is not well preserved. Did human women contribute to Neanderthal genomes over 200,000 years ago? 2017-07-18T04:00:00Z Your natural endogenous opioids in your brain are there to make you feel connected and safe and loved. ‘Addiction is love gone awry’: We shouldn’t shame drug users, says best-selling author 2017-04-05T04:00:00Z But perhaps the most striking example of a replicating endogenous retrovirus is in koalas. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z The best binding affinity for an endogenous class I MHC allele is shown in black. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z But over the generations, the viral DNA mutates, and endogenous retroviruses eventually lose the ability to infect new cells. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z These high contamination and low endogenous DNA levels mean that it will be difficult to obtain a nuclear genome from this bone. Did human women contribute to Neanderthal genomes over 200,000 years ago? 2017-07-18T04:00:00Z As such, when PS levels increase, the rate of endogenous PS biosynthesis is quickly reduced in a compensatory manner. LACTB is a tumour suppressor that modulates lipid metabolism and cell state : Nature : Nature Research 2017-03-21T04:00:00Z Much of the focus on transposable elements—and particularly, on endogenous retroviruses and LINE-1s—has centered on the possible negative repercussions of these DNA insertions. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Our results suggest that expansion of endogenous Ig neoantigen-specific CD4+ T cells may represent a viable treatment strategy for lymphoma. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z After a single infection, an endogenous retrovirus may build up hundreds of copies of itself in its host’s DNA. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z His most fertile period seems to have been the years between his first work on the impossibility theorem in the early 1950s and his pioneering contribution, in 1962, to what became endogenous growth theory. Kenneth J. Arrow (1921-2017) : Nature : Nature Research 2017-03-28T04:00:00Z Organisms use endogenous clocks to anticipate regular environmental cycles, such as days and tides. The genomic basis of circadian and circalunar timing adaptations in a midge : Nature : Nature Research 2016-11-20T05:00:00Z But work tracing back to the 1980s has suggested that endogenous retroviruses may also support reproductive function in some way6. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z The best binding affinity for an endogenous class I MHC allele is shown in black. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z Some endogenous retroviruses are unique to humans, but others are found in a variety of species. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z The pill actually stops the production of those endogenous hormones via the brain. How does the pill work? You asked Google - here’s the answer | Holly Grigg-Spall 2016-11-09T05:00:00Z But doses of prescription opioids are orders of magnitude higher than our endogenous levels, Angst says. Why painkillers sometimes make the pain worse 2016-11-03T04:00:00Z The risks of transposable elements to human health are a concern when it comes to the tissue transplants we receive from other species, such as from pigs, which have porcine endogenous retroviruses. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z To lower glucose levels, diabetics need to increase insulin, either by taking medication that increases their own endogenous production or by injecting insulin directly. Before You Spend $26,000 on Weight-Loss Surgery, Do This 2016-09-10T04:00:00Z We make proteins from endogenous retroviruses to carry out functions we depend on. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z The pill has to disrupt the endocrine system in order to stop the production of endogenous hormones. How does the pill work? You asked Google - here’s the answer | Holly Grigg-Spall 2016-11-09T05:00:00Z The son of a former Colorado governor, Mr. Romer is a leading advocate of endogenous growth theory, which holds that investment in human capital, knowledge and technology are the major drivers of economic expansion. World Bank Names Paul Romer as Chief Economist 2016-07-18T04:00:00Z But some cancer scientists are thinking about co-opting endogenous retroviruses to use against cancer. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z He is known as a proponent of the “endogenous growth theory,” which holds that investment in human capital, ideas and technology are the major drivers of economic growth. World Bank Names Paul Romer as Chief Economist 2016-07-17T04:00:00Z Once retroviruses become inherited stowaways, scientists refer to them as endogenous retroviruses. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z Two years later, British biologists discover enkephalins, a group of endogenous opioids — or endorphins. Painful progress : Nature : Nature Publishing Group 2016-07-12T04:00:00Z Over time these so-called endogenous retroviruses lose even the ability to replicate, becoming harmless fragments adrift in the human genome. Study Finds Surprising Benefit of Viral DNA: Fighting Other Viruses 2016-03-03T05:00:00Z In one example, a 2015 study found elevated levels of one embedded virus, known as human endogenous retrovirus K, in the brains of individuals with amyotrophic lateral sclerosis, also known as Lou Gehrig's disease3. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Abundant transfer RNA fragments in maturing mammalian sperm regulate expression of endogenous retroelements in the embryo. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals | Science 2016-01-21T05:00:00Z At first, endogenous retroviruses coax cells to make more retroviruses that can infect other cells. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z In particular, their DNA is full of retroviruses, known specifically as porcine endogenous retroviruses, or PERVS. No pig in a poke 2015-10-15T04:00:00Z Moreover, in driving the biological responses of the genetically modified T cells, it suppresses confounding endogenous TCR signal transduction. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z Other studies of endogenous viruses might have clearer implications for human health, and so scientists are looking at the activity of these transposable elements in a wide range of other animals, including the house cat. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Abundant transfer RNA fragments in maturing mammalian sperm regulate expression of endogenous retroelements in the embryo. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals | Science 2016-01-21T05:00:00Z Even after being hobbled, these endogenous retroviruses can still sometimes make their proteins. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z These sequences, some of which produce porcine endogenous retroviruses, or PERVs, present one of many barriers for transplanting whole organs from pigs to humans. Gene editing could make pig organs suitable for human transplant one day 2015-10-14T04:00:00Z A small proportion of the vector integrated at the albumin locus and became expressed from its endogenous promoter, which removed the requirement for both endonucleases and the transfer of a promoter within the vector. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z The ability for these endogenous retroviruses to awaken from the genome “is more widespread than has been previously appreciated,” says virologist Renée Douville at the University of Winnipeg in Canada. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z In tests on early pig embryos, Prof Church was able to eliminate all 62 copies of porcine endogenous retroviruses from the pig cells using Crispr. 'GM could make pig organs for humans' - BBC News 2015-10-12T04:00:00Z Just as we have defenses against free-living viruses, we have also developed defenses against endogenous retroviruses. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z The parks host one of the highest densities of endogenous marine species on the planet. Chile, United States create new marine conservation parks 2015-10-05T04:00:00Z This depletes endogenous progenitors and differentiated cells in the bone marrow — as well as the lymphoid organs, in some cases — and favours engraftment of the ex vivo gene-corrected cells. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z “There is a fair amount of rumor virology around endogenous retroviruses causing disease.” Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z Why it matters Therapies based on endogenous molecules are a mainstay of medicine. Cannabis: 4 big questions : Nature : Nature Publishing Group 2015-09-22T04:00:00Z In many kinds of tumor cells, for instance, scientists find proteins produced by endogenous retroviruses. Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z They are there to respond to endogenous neurotransmitters that control things like hunger, reproductive function and memory. Fake Weed Leads to a Real Drug Crisis 2015-08-25T04:00:00Z The real breakthrough in molecular paleontology has been the recovery of endogenous proteins from ancient dinosaurs, work pioneered since the first "Jurassic Park" by Mary Schweitzer. Awesome Dinos, Iffy Science Inhabit "Jurassic World" 2015-06-18T04:00:00Z “Upregulation of this group of endogenous viruses is a very common finding.” Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z It’s possible, in other words, that this endogenous retrovirus protects embryos from other viruses. Ancient Viruses, Once Foes, May Now Serve as Friends 2015-04-23T04:00:00Z That discovery has fueled a long-running debate: Do endogenous retroviruses help cause cancer? Ancient Viruses Are Buried in Your DNA 2017-10-04T04:00:00Z This is why, in my interpretation, Stiglitz argues that the elasticity of substitution greater than 1 combined with endogenous technical progress leads ultimately to an explosive equilibrium. Joe Stiglitz's Worries About The Robot Economy Are An Impossible Outcome 2015-04-18T04:00:00Z Finally, and most importantly, it is not obvious to non-economists that wages are endogenous. Trade Treaties With Labor Protections Don't Affect Average Wages 2015-02-25T05:00:00Z Some retrovirologists caution that the evidence remains thin that this endogenous virus causes ALS. Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z A new study published in the journal Nature on Monday suggests that endogenous retroviruses spring to life in the earliest stages of the development of human embryos. Ancient Viruses, Once Foes, May Now Serve as Friends 2015-04-23T04:00:00Z All that said, some plants do show endogenous rhythms, or an internal clock. Planting a Clock That Tracks Hours by Flowers 2015-01-28T05:00:00Z Not only was it found in abundance, it "looked considerably more like fish insulin than endogenous snail insulin." Fish-eating snails stun their prey with insulin 2015-01-19T05:00:00Z In this way endogenous retroviruses may help brain cells more intricately regulate their gene expression, thereby allowing them to become more complex. Ancient Viruses Gain New Functions in the Brain 2015-01-19T05:00:00Z The larger the animal, they found, the fewer endogenous retroviruses it acquired. How Big Animals Deter Cancer 2014-09-23T04:00:00Z But scientists are finding that some endogenous retroviruses do wake up, and at the strangest time. Ancient Viruses, Once Foes, May Now Serve as Friends 2015-04-23T04:00:00Z The interest rate changes are not exogenous changes that will harm the economy; they are endogenous, the result of stronger economic growth and part of the automatic dampening that occurs as the economy expands. Interest Rate Forecast 2014-2015 2014-05-28T04:00:00Z One possible takeaway from this divergence is that productivity is often endogenous to the real wage. Labour markets: A theory of troubles 2014-02-17T09:36:58Z “There seems to be a different mechanism regulating endogenous retroviruses in brain cells than in other cells,” Jakobsson says. Ancient Viruses Gain New Functions in the Brain 2015-01-19T05:00:00Z Functional analyses are also necessary to clarify when a new neuron achieves the needed function, even if its other features do not match endogenous neurons. [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z RNA sequencing revealed that NAC and vitamin E, which are structurally unrelated, produce highly coordinated changes in tumor transcriptome profiles, dominated by reduced expression of endogenous antioxidant genes. [Research Articles] Antioxidants Accelerate Lung Cancer Progression in Mice 2014-01-29T19:55:10.534Z Studying endogenous mRNA in live mouse tissues provides insight into its dynamic regulation within the context of the cellular and tissue microenvironment. [Report] Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse 2014-01-23T19:26:31.396Z This first glimpse of endogenous mRNA behavior raises interesting questions about how RNA dynamics are coupled to translation. [Perspective] mRNA, Live and Unmasked 2014-01-23T19:25:48.854Z This isn’t enough to conclude that endogenous retroviruses are responsible for these behavioral changes, but taken together with the other findings of this study, they are likely suspects. Ancient Viruses Gain New Functions in the Brain 2015-01-19T05:00:00Z With improved capacity to screen large numbers of samples for those with high proportions of endogenous ancient DNA, paleogenomics is poised to become a key technology to better understand recent evolutionary events. [Review] A Paleogenomic Perspective on Evolution and Gene Function: New Insights from Ancient DNA 2014-01-23T19:25:19.779Z Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. [Research Article] Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer 2014-01-09T18:56:14.192Z So patients must also be treated with drugs or radiation to deplete their endogenous immune cells and allow the newly infused T cells to gain hold and fill the body. Adoptive cell therapy: Honing that killer instinct 2013-12-18T18:50:59.882Z In developing mouse somatosensory cortex, endogenous Btbd3 translocated to the cell nucleus in response to neuronal activity and oriented primary dendrites toward active axons in the barrel hollow. [Report] BTBD3 Controls Dendrite Orientation Toward Active Axons in Mammalian Neocortex 2013-12-04T22:56:58.093Z To avoid disruption of other cellular controls, exogenous ribozyme-based controllers that interfaced with the endogenous control circuits were used, which avoided genetic alteration to the cells. [Research Article] Dynamically Reshaping Signaling Networks to Program Cell Fate via Genetic Controllers 2013-09-19T17:56:29.160Z A recent study analysed an extensive catalogue of mutations in 30 of the most common cancer types and uncovered more than 20 signatures of processes that mutate DNA, driven by both exogenous and endogenous factors. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z Exogenous PU.1 expression in progenitors increases endogenous PU.1 levels by inducing cell cycle lengthening, implying positive feedback between a regulatory factor and the cell cycle. [Report] Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation 2013-08-09T19:27:05.773Z Surprisingly, the same mice showed a threefold increase in total endogenous murine Tau in CSF at the stages when Aβ pathology became prominent. [Reports] Changes in Amyloid-{beta} and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein 2013-07-17T18:55:01.147Z The credit crunch now suffocating peripheral Europe is not just the endogenous consequence of weak growth or the Greek crisis; it is also rooted in deliberate policy choices. Lehman, PSI and the consequences of credit policy: The third lever of macroeconomics 2013-05-02T19:20:57Z The endogenous cannabinoid system has profound effects on mood, appetite, blood pressure and many more essential functions. Online highs are old as the net: the first e-commerce was a drugs deal 2013-04-19T13:51:53Z With insufficient endogenous healing and no economic escape velocity, the effectiveness of central banks' policies wanes and political dysfunction increases, leading to financial losses, volatility spikes and huge risk-management challenges. The eurozone's fate now rests with the central banks 2013-03-21T15:19:04Z With the determination of structures of increased resolution and application of complementary approaches, one can gain insights into how endogenous small molecules and the near native environment of the receptor can modulate function. Molecular signatures of G-protein-coupled receptors 2013-02-13T18:21:29.900Z TIC10 is an efficacious antitumor therapeutic agent that acts on tumor cells and their microenvironment to enhance the concentrations of the endogenous tumor suppressor TRAIL. [Research Articles] Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects 2013-02-06T21:55:05.167Z But before the cirisis the relationship between the policy rate and what borrowers paid was assumed to be either constant, or endogenous to monetary policy or the business cycle. Lehman, PSI and the consequences of credit policy: The third lever of macroeconomics 2013-05-02T19:20:57Z That region is saturated with neurons containing dopamine and endogenous opioids, which are involved in pleasure and desire related both to drugs and to ordinary experiences like eating, love and sex. Surgery for Addiction Burns Brain's Pleasure Center 2012-12-13T13:35:34Z Second, those transposable elements are particularly likely to be endogenous retroviruses, rather than any of the other sorts of element. RNA-only genes: The origin of species? 2012-11-29T17:39:56Z The pig genome contains fewer endogenous retroviruses than many vertebrates, including humans and mice, and most PERVs were characterized as defective. Analyses of pig genomes provide insight into porcine demography and evolution 2012-11-14T18:22:24.580Z Most bone fragments would be expected to contain less than 5 percent of the individual's endogenous DNA, but this fortuitous finger had a surprising 70 percent, the researchers noted in the study. New DNA Analysis Shows Ancient Humans Interbred with Denisovans 2012-08-30T23:15:00.443Z The main challenge in using native hosts to convert feedstocks into advanced biofuels is to overcome the endogenous regulation of biofuel-producing pathways to achieve high yields. Microbial engineering for the production of advanced biofuels 2012-08-15T17:22:19.783Z Putting an extra copy of a gene into a plant can activate a self-defense mechanism known as RNA interference that shuts down both the extra copy and the endogenous gene. Growers Fret Over a New Apple That Won’t Turn Brown 2012-07-13T15:22:01Z And fourth, lincRNAs containing one particular type of endogenous retrovirus are especially active in pluripotent stem cells, the embryonic cells that are the precursors of all other cell types. RNA-only genes: The origin of species? 2012-11-29T17:39:56Z Putting an extra copy of a gene into a plant can trigger a self-defense mechanism known as RNA interference that shuts down both the extra copy and the endogenous gene. Growers Fret Over a New Apple That Won’t Turn Brown 2012-07-12T21:48:23Z At two I began a lifetime of chronic asthma, full blown obsessive compulsive disorder starting around puberty, years of scrupulous hyper-religiosity and hints of endogenous depression. Taming the Psychopath within 2012-06-29T17:45:08.043Z He is often referred to as part of what Mr. Chávez’s followers call the endogenous right, a more conservative wing within Mr. Chávez’s movement. Hugo Chávez Forces Venezuelans to Contemplate a Void 2012-06-12T02:10:16Z Rootstocks apparently endogenous.—The few genera differ so much in the flower and fruit that they are separated into the three following suborders. The Manual of the Botany of the Northern United States Including the District East of the Mississippi and North of North Carolina and Tennessee 2012-04-12T02:00:30.140Z What seems to be happening is that endogenous retroviruses are jumping around in an arbitrary way within the genome. RNA-only genes: The origin of species? 2012-11-29T17:39:56Z Partaking of two natures, as the perianth of some endogenous plants, where the outer surface is calycine, and the inner petaloid. Webster's Unabridged Dictionary 2012-03-24T02:00:23.513Z In a 2008 study focused on India, an economics professor said “language learning and linguistic diversity ought to be taken as endogenous to the process of economic development.” India Ink: If Bilingual Is Good, Is Trilingual Better? 2012-03-20T07:16:26Z In the process of transformation the increased protoplasm of the epithelia first exhibits shining homogeneous lumps, which, after an intermediate stage of vacuolation, undergo an endogenous metamorphosis into nucleated bodies with a reticulum in each. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z The hypothesis supposes that the release of the endogenous opioids is for the purpose of killing pain and allowing us to run longer. It hurts so good: the runner's high 2012-03-12T18:15:00.293Z Transposable elements come in several varieties, but one group of particular interest are known as endogenous retroviruses. RNA-only genes: The origin of species? 2012-11-29T17:39:56Z Furthermore, changes in orbitofrontal cortex binding correlated significantly with problem alcohol use and subjective high in heavy drinkers, suggesting that differences in endogenous opioid function in these regions contribute to excessive alcohol consumption. [Research Articles] Alcohol Consumption Induces Endogenous Opioid Release in the Human Orbitofrontal Cortex and Nucleus Accumbens 2012-01-11T20:25:10.627Z When the mosquito next bites a man, numbers of them are injected, together with the minute drop of saliva, into his blood, where they begin a fresh endogenous cycle. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z He does not believe in the probability of an exclusively endogenous origin of the cellular elements of croup membrane; in fact, he doubts the occurrence of an endogenous formation of pus-globules in epithelium. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z There is no question that endogenous opioid release reduces our sensitivity to pain, but it’s very hard to prove this kind of hypothesis. It hurts so good: the runner's high 2012-03-12T18:15:00.293Z It is not hereby meant to ignore the fact that differential responses to dominant environmental variables occur within a species, indicating endogenous control over timing of breeding. The Breeding Birds of Kansas 2011-08-27T02:00:24.797Z Studies in animals suggest that release of endogenous opioids by ethanol promotes further consumption. [Research Articles] Alcohol Consumption Induces Endogenous Opioid Release in the Human Orbitofrontal Cortex and Nucleus Accumbens 2012-01-11T20:25:10.627Z The liberated merozoites proceed to infect fresh blood corpuscles and a new endogenous cycle is started. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z They are characterized by their unicellular nature, their power of rapid budding, their capacity for fermenting various sugars, and their power of forming endogenous 340 spores. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z But being an endogenous tree, its pithy interior makes it always soft at the center, or heart. The Palm Tree Blessing 2011-07-11T02:00:05.463Z Many people say the sleep-inducing supplements, which contain a synthetic form of the endogenous hormone, are helpful for combating jet leg or sleeplessness. Lazy Cakes: A Sleepytime Snack Elicits Public-Health Outrage 2011-05-16T17:10:00Z This means that the neural signals the animal employs to get going are "organized and activated by presynaptic brain neurons, not by endogenous mechanisms," they explained in their study. Consider the crayfish: How a claw-full of neurons makes crustaceans crawl [Video] 2011-04-14T21:15:00.490Z In this type of illness the endogenous multiplication of the parasites is very great and rapid, and brings about an enormous diminution in the number of healthy red blood corpuscles. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z The sporangium with its endogenous spores has been compared with an ascus, and on these grounds the group is placed among the Ascomycetes—a very doubtful association. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z It is an endogenous tree, and the cambium layer does not obtain. The Palm Tree Blessing 2011-07-11T02:00:05.463Z These, from the peculiarity of their endogenous texture, are less liable to be shattered by shot, and the bullet buries itself harmlessly in the wood. Osceola the Seminole The Red Fawn of the Flower Land 2011-03-22T02:00:20.123Z On the one hand, improving endogenous growth dynamics in the U.S. and core Europe, and particularly Germany. Birinyi Buying as Biggest Bull Market Since ’55 Hits Third Year 2011-03-09T03:33:15Z Ligni�res has observed a kind of multiple fission in the stomach, several very minute bodies, consisting mostly of chromatin, being formed, which may serve for endogenous reproduction. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z A fourth group is formed by the endogenous woods, like yuccas and palms, which do not grow by such additions. Wood and Forest 2011-03-01T03:00:42.647Z We have in the botanical world the exogenous and the endogenous tree. The Palm Tree Blessing 2011-07-11T02:00:05.463Z The positive expectancy effects were associated with activity in the endogenous pain modulatory system, and the negative expectancy effects with activity in the hippocampus. [Research Articles] The Effect of Treatment Expectation on Drug Efficacy: Imaging the Analgesic Benefit of the Opioid Remifentanil 2011-02-16T19:55:15.320Z It seems probable that the former serve for endogenous or auto-infection, and the latter for infecting fresh hosts. Encyclopaedia Britannica, 11th Edition, Volume 9, Slice 3 "Electrostatics" to "Engis" 2011-02-06T03:00:53.093Z "This was accomplished by the homing of the body's endogenous stem cells — another first." Professor tries to make knee replacements less bionic 2011-01-26T16:05:04Z From where, we might imagine, it is only a short hop to galvanising teenage interest in the hard economics of endogenous growth theory. Ed Miliband's infatuation with American football 2010-11-22T20:00:00Z But I'd say that's not a physical law but a strategy, a sense in which innovation is endogenous to the economy. Business Innovation 'Made Us Human' and Moves Us Forward 2010-05-28T15:29:00Z The PET scan showed that the endogenous endorphin system in the brains of the subjects was activated. Mind Over Meds 2010-04-23T19:47:00Z An endogenous stem has no clear distinction of pith, bark, and wood, concentrically arranged, no silver grain, no annual layers, no bark that peels off clean from the wood. The Elements of Botany For Beginners and For Schools When the uric acid is formed in this manner as the result of the metabolism of the body tissues, it is known as “endogenous.” Dietetics for Nurses The effects of a Coccidian infection upon the host as a whole depend largely upon the extent to which endogenous multiplication of the parasites takes place. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 5 "Clervaux" to "Cockade" Nor is the extraordinary productiveness of a single tree the only point worthy of notice, for, being endogenous plants, devoid of branches, an unusual number of them can grow in a small space. The Church of England Magazine - Volume 10, No. 263, January 9, 1841 A. Various stages in the development of the endogenous spores in a Clostridium—the small letters indicate the order. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Trees are either exogenous—that is to say, grow by means of successive layers on the outside; or they endogenous—which means that they are increased by layers in the inside. In the Wilds of Africa Here and there, patches of dry mezquite-trees would have caught like tinder; but in most places, a succulent endogenous vegetation formed three parts of the jungle, and rendered it “fire-proof.” The War Trail The Hunt of the Wild Horse It is the fruit of an herbaceous endogenous plant of the natural order Musaceae. The Philippine Islands The following typographic errors have been fixed: Page 20—servicable amended to serviceable—"... both exogenous and endogenous, render them extremely serviceable to mankind." The Church of England Magazine - Volume 10, No. 263, January 9, 1841 “Are you much hurt, old fellow?” he cried hoarsely, as he realised the fact that the keen spear had passed diagonally through the youth’s breast before it buried itself in the soft endogenous tree. Middy and Ensign The true psychoses develop out of endogenous causes, attack and manifest themselves in the prisoner in the same way as in any law-abiding individual in freedom. Studies in Forensic Psychiatry The woods are principally eucalypti, as might be supposed, but endogenous trees are found toward the north, and are shown. Lippincott's Magazine of Popular Literature and Science, Volume 22. October, 1878. It is an endogenous plant, the stem of which is enclosed in layers of half-round petioles. The Philippine Islands The mechanical properties of the stems of trees, both exogenous and endogenous, render them extremely serviceable to mankind. The Church of England Magazine - Volume 10, No. 263, January 9, 1841 Reproduction takes place by endogenous budding, and the swarm spores are flat or lenticular with a distinct ciliary girdle. Marine Protozoa from Woods Hole Bulletin of the United States Fish Commission 21:415-468, 1901 They differ from the genuine epilepsy by the absence of the characteristic dementia, of attacks of petit mal, and by the fact that the seizures are never purely endogenous in origin. Studies in Forensic Psychiatry Certain it is that if Federation is to be brought about, the movement must be endogenous. Town Life in Australia Keynes�s General Theory can be generalised even further by the inclusion of endogenous government in the model, and in particular economic policy making itself as that is guided by economic theory. Definition & Reality in the General Theory of Political Economy Their growth is essentially endogenous, and will probably be found when examined aborigine to approximate to that of Cycadeæ, although these last are of a more exogenous than endogenous nature. Journals of Travels in Assam, Burma, Bhootan, Afghanistan and the Neighbouring Countries The names proposed in the pasigraphico-geognostic plan were borrowed from De Candolle's nomenclature, in which 'endogenous' is synonymous with monocotyledonous, and 'exogenous' with dicotyledonous plants. COSMOS: A Sketch of the Physical Description of the Universe, Vol. 1 And it is not till Cainozoic times that we have the endogenous grasses and palms and angiospermous exogens. Creation and Its Records Of the ten species named as rarest among American endogenous plants by Dr. Gray, in his valuable essay on the statistics of our Northern Flora, all but one are Orchids. The Atlantic Monthly, Volume 10, No. 62, December, 1862 It follows from this that the Constitution should warrant for the Economic Supreme Court: � It would be possible for the Court to use a model with an endogenous government. Definition & Reality in the General Theory of Political Economy However, he goes further and refers to endogenous intoxication, to disturbed states of the constitution, due to disturbances in glandular activity or to excess of certain internal secretions. Hormones and Heredity It remains for future inquirers to determine how transformation can have been effected without contact with the endogenous stone, where strata of dolomite are found to be interspersed in imestone. COSMOS: A Sketch of the Physical Description of the Universe, Vol. 1 The word endogenous, inside-growing, is not, therefore, a correct one to describe the growth of most monocotyledons, for the growth takes place where the leaves originate, near the exterior of the stem. Outlines of Lessons in Botany, Part I; from Seed to Leaf So loose is the internal distribution of its tissues, that it was for some time held doubtful to which of the two great vegetable divisions, exogenous or endogenous, it belonged. The Atlantic Monthly, Volume 02, No. 11, September, 1858 The basic proposition of this book hence is that we can extend the current �neoclassical synthesis� by including endogenous government in the model, so that we arrive at a truly general Political Economy. Definition & Reality in the General Theory of Political Economy Man is that noble endogenous plant which grows, like the palm, from within, outward. Representative Men The same may happen among the spherical forms, which only in rare instances form endogenous spores. The Story of Germ Life Thank Heaven, sir, you have not the irritable temperament, that you are not goaded to madness by your endogenous sneers, by the eternal wrangling of an uncomfortable soul and body. The Wheels of Chance: a Bicycling Idyll There is no good evidence that they have any special resisting power to heat like endogenous spores, and bacteriologists in general are inclined to regard them simply as resting cells. The Story of Germ Life The genus Bacillus, for instance, is the name given to all rod-shaped bacteria which form endogenous spores, etc. The Story of Germ Life Man is endogenous, and education is his unfolding. Representative Men |
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