You have to be responsible for something that happened; usually it's an accident.

你必须对发生的事情负责； 通常这是一个意外。

" To administer, " in addition to meaning to be responsible for something, can also mean to give someone a drug.

“管理” 除了意味着对某事负责之外，还可以意味着给某人服用药物。

" To be tasked with" something is a phrasal verb meaning to be given the job to do something or, more generally, to be responsible for something, for doing something.

“To be tasked with” something 是一个短语动词，意思是被赋予做某事的工作，或者更一般地说，对某事负责，做某事。

This is an idiomatic expression; " to hold the bag, " or " to be left holding the bag" means to be responsible for something when other people don't do their work.

。 这是一个惯用语；“to hold the bag” 或“to be left holding the bag” 意思是当其他人不做他们的工作时对某事负责。