Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.

双酯型的去氧乌头碱的毒性较高，当它被肠内细菌转化为单酯型和脂类生物碱时会使其毒性降低。