But as it dispersed, Spyrou says, it picked up just a single genetic mutation.

但斯派尤表示，随着病菌的扩散，其只发生过一次基因突变。

So gene therapies are fantastic for diseases that can be attributed to a single gene mutation or single root cause.

因此，对于可归因于单一基因突变或单一根本原因的疾病，基因疗法非常有效。

For conditions caused by a single genetic mutation, like cystic fibrosis or sickle cell anemia, CRISPR offers a potential cure.

对于由单一基因突变引起的疾病，如囊性纤维化或镰状细胞性贫血，CRISPR 提供了一种潜在的治疗方法。

There is clear evidence that a single gene mutation can lead to obesity, such as, for instance, leptin deficiency and POMC deficiency.

有明确的证据表明，单个基因突变会导致肥胖，例如瘦素缺乏和 POMC 缺乏。

Instead of making a medicine that treats a single mutation to a gene, it would be possible to fix many types of mutation with one correction.

我们不需要制作一种药物来治疗某个基因的单一突变，而是可以通过一次修正来修复多种类型的突变。