" Unprecedented and even irreversible changes are happening to this planet."

“这个星球正在发生前所未有、甚至不可逆转的变化。”

Chronic pancreatitis is inflammation due to irreversible changes to the pancreatic structure, like fibrosis, atrophy and calcification.

慢性胰腺炎是胰腺结构发生不可逆改变导致的炎症，例如纤维化、萎缩和钙化。

Many of our planets systems getting precariously close to sudden potentially irreversible change.

我们的许多行星系统都岌岌可危地接近突然的、可能不可逆转的变化。

Here again you see risk assessment, darker the red, higher the likelihood of causing irreversible change in the climate system.

这里您可以再次看到风险评估， 红色越深，导致气候系统不可逆转的变化的可能性就越高。

He said in the report the shrinking of the last remaining glaciers in Africa " signals the threat of irreversible change to the Earth system" .

他在报告中说，非洲仅存的冰川的萎缩" 标志着地球系统面临不可逆转的变化的威胁" 。

Alright as a quick recap, chronic pancreatitis happens when irreversible changes to the pancreatic structure, like fibrosis, atrophy and calcification begin to decrease the functions of the organ.

得！快速回顾一下：当胰腺结构发生不可逆改变（如纤维化、萎缩和钙化）造成器官功能开始减退时，慢性胰腺炎发生。

Since the year 2000, a quarter of Uganda's wetlands have been lost and average of nearly 5,000 hectares a year causing rapid and irreversible change to the cradle of the cranes.

自2000年以来，乌干达丧失了四分之一的湿地，平均每年丧失近5,000公顷的湿地，这给鹤类的摇篮——湿地造成了迅速而不可逆转的变化。

Initially these inflammatory changes are completely reversible, but over the years irreversible changes start to take place —edema, scarring, and fibrosis build up, leading to thickening of the epithelial basement membrane, which permanently reduces the airway diameter.

最初这些炎症变化是完全可逆的，但是随时间进展，不可逆的变化开始发生，出现水肿、瘢痕、纤维化等症状，导致上皮基底膜增厚，从而永久性地减小气道直径。