When these anti-glycan IgG antibodies bind to abnormal IgA1, immune complexes are formed.

当这些抗糖基化的IgG抗体与异常IgA1结合，形成免疫复合物。

Two lines would be IGG or IGM and then the third line would be that you have both.

两条线就代表你体内存在IGG或IGM（被感染了），如果有三条线那你就两者都感染了。

When the abnormal IgA1-IgG immune complexes deposit in the mesangium, the alternative complement pathway is activated, leading to the release of proinflammatory cytokines and migration of macrophages into the kidney, all of which contributes to glomerular injury.

当异常的IgA1-IgG免疫复合物沉积在系膜上时，补体旁路途径被激活，导致促炎因子的释放，同时促进巨噬细胞向肾迁移，以上所有反应会导致肾小球的损伤。