| 单词 | Rb |
| 例句 | Of the five elements Al, Cl, I, Na, Rb, which has the most exothermic reaction? Chemistry 2019-02-14T00:00:00Z As the cell increases in size, Rb is slowly phosphorylated until it becomes inactivated. Biology for AP Courses 2022-06-09T00:00:00Z RB1 acts as a suppressor because its protein, Rb, inhibits a transcription factor involved in cell proliferation. The RNA and protein landscape that could bring precision medicine to more people 2020-09-22T04:00:00Z However, as would be expected, these inhibitors are not effective if Rb is not expressed in the tumours4. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z "By specifically targeting pathways controlled by the Rb protein, it would be possible to switch-off the messages that encourage cancer cells to invade, and inhibit the spread of the tumour." NI scientists in cancer discovery 2012-08-08T06:39:49Z Based on their positions in the periodic table, list the following atoms in order of increasing radius: Mg, Ca, Rb, Cs. Chemistry 2019-02-14T00:00:00Z Rb releases E2F, which can now turn on the gene that produces the transition protein, and this particular block is removed. Biology for AP Courses 2022-06-09T00:00:00Z ARF backs up Rb, an important anticancer protein, by limiting the ability of mature cells to divide and replicate. Removing a Barrier to Regrowing Organs 2010-08-10T14:48:00Z The authors studied the effect of Rb loss in mouse models of the cancer. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z But it is possible that Rb or other proteins in the healthy tissue surrounding other types of cancer, may play a similar role in regulating the spread of tumour cells. NI scientists in cancer discovery 2012-08-08T06:39:49Z One of the two tumor suppressor genes is an ancient gene, known as Rb, which is naturally inactivated in newts and fish when they start regenerating tissue. Two New Paths to the Dream: Regeneration 2010-08-06T03:06:00Z Rb exerts its regulatory influence on other positive regulator proteins. Biology for AP Courses 2022-06-09T00:00:00Z The team tested the idea by taking muscle cells from mice and temporarily depleting the Rb and ARF inside. Removing a Barrier to Regrowing Organs 2010-08-10T14:48:00Z The absence of Rb resulted in loss of cellular differentiation and an increase in the spread of cancer cells to other sites in the body through a process called metastasis. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z A so-called tumor suppressor gene called retinoblastoma, or Rb, helps control this process in mammals. Plain cells turned into beating heart cells: study 2010-08-05T17:21:00Z Mammals possess both the Rb gene and a backup, called the Arf gene, which will close down a cancer-prone cell if Rb fails to do so. Two New Paths to the Dream: Regeneration 2010-08-06T03:06:00Z The collective function of the best- understood tumor suppressor gene proteins, Rb, p53, and p21, is to put up a roadblock to cell cycle progression until certain events are completed. Biology for AP Courses 2022-06-09T00:00:00Z A test for Rb is already being used to screen patients for use of PD-0332991 in the ongoing clinical trials. Pfizer, Onyx drug offers hope against brain cancer 2010-03-30T17:00:00Z Walter and colleagues studied the effects of Rb loss in a mouse model of a common form of lung cancer called lung adenocarcinoma. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z When they blocked both Rb and ARF in mouse heart muscle cells, they started to grow and divide. Plain cells turned into beating heart cells: study 2010-08-05T17:21:00Z The Stanford team shut off both Rb and Arf with a chemical called silencing-RNA and found the mouse muscle cells started dividing. Two New Paths to the Dream: Regeneration 2010-08-06T03:06:00Z Group I.: the alkali metals Li, Na, K, Rb, Cs, and also Ag, monovalent; Cu, monovalent and divalent; Au, monovalent and trivalent. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 1 "Châtelet" to "Chicago" The results provide some of the strongest in vivo evidence so far to support a role for Rb loss in driving not only cancer initiation, but also its progression. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z The authors used genetically engineered animals to control whether and when Rb was made in lung cancer cells. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z The authors observed that the molecular changes that lead to progression and metastasis in this lung cancer model are strikingly different, depending on whether Rb is present or absent. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z Another key observation made by Walter and colleagues is that tumours that lack Rb do not upregulate a signalling pathway containing the kinase MAPK, which is often activated in lung adenocarcinoma. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z |
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