| 单词 | colchicine |
| 例句 | The results showed that both sharks can taste bitter substances also perceived by humans, such as colchicine or bile acid. Evolution of taste: Early sharks were able to perceive bitter substances 2023-11-13T05:00:00Z Colchicum corms contain colchicine, a powerful alkaloid that’s been used in pharmaceuticals for years. 'Gardening Can Be Murder': The safest place to encounter these toxic plants 2023-10-28T04:00:00Z After Ms. Bowman’s death, investigators collected information about Dr. Bowman’s internet searches, including research they said he had done earlier in August into the drug colchicine, which is used to treat gout. Poison Specialist Accused in Wife’s Death, Authorities Say 2023-10-25T04:00:00Z The medical examiner’s office halted the order for cremation, citing suspicious circumstances, according to a criminal complaint, and an autopsy showed Betty Bowman died from toxic effects of colchicine, a medicine used to treat gout. Poison specialist and former medical resident at Mayo Clinic is charged with poisoning his wife 2023-10-24T04:00:00Z A chemical called colchicine is then applied to cells to arrest condensed chromosomes in metaphase. Biology for AP Courses 2022-06-09T00:00:00Z In addition to identifying three drugs that treat COVID-19, the study helped rule out several others, including aspirin, the antimalarial hydroxychloroquine, the HIV drug combination lopinavir/ritonavir, and colchicine, an anti-inflammatory drug. Arthritis drug reduces mortality in severe COVID-19, huge clinical trial finds 2022-03-02T05:00:00Z Promising results over the past year from two placebo-controlled trials of colchicine, a drug used to treat arthritic conditions such as gout, “provide independent confirmation of what we saw in CANTOS”, Ridker says. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z Tests found colchicine in Ms. Bowman’s blood and urine, the complaint said, and the medical examiner determined that her death was a homicide caused by the toxic effects of colchicine. Poison Specialist Accused in Wife’s Death, Authorities Say 2023-10-25T04:00:00Z He did calculations that match the lethal dosage rate for colchicine on Aug. 10. Poison specialist and former medical resident at Mayo Clinic is charged with poisoning his wife 2023-10-24T04:00:00Z One treatment for gout is colchicine, a medication that inhibits mitosis. Biology for AP Courses 2022-06-09T00:00:00Z Until his discoveries, the standard therapies were drugs such as colchicine, an anti-inflammatory that doctors have deployed against conditions as diverse as cancer, cirrhosis, and heart arrhythmias. This genetic sleuth has uncovered a new category of disease marked by sporadic fevers and inflammation 2021-09-22T04:00:00Z Some cardiologists are already beginning to prescribe colchicine for certain people with cardiovascular disease. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z Research on the gout drug colchicine caused similar whiplash. Scientists seek COVID treatment answers in cheap, older drugs 2021-03-30T04:00:00Z The trial is still testing aspirin, an anti-inflammatory drug named colchicine, an antibody cocktail from drug company Regeneron, and baricitinib, another drug used to treat rheumatoid arthritis. World’s largest COVID-19 drug trial identifies second compound that cuts risk of death 2021-02-11T05:00:00Z Support is also required for using other available FDA-approved off-the-shelf drugs that might help prevent hospitalizations, as in the recent findings indicating colchicine, a common gout medication, prevents COVID-19 hospitalizations. Vaccines Alone Are Not Enough to Beat COVID 2021-02-07T05:00:00Z It was found that the average length of time patients needed oxygen therapy was four days for those treated with additional colchicine, compared with 6.5 days for those who received a standard type of treatment. Gout drug could reduce Covid hospital stays, new research finds 2021-02-04T05:00:00Z But researchers are also launching additional trials of colchicine and other anti-inflammatory drugs. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z The patient told her about the pain and swelling and the treatment with multiple courses of steroids and now colchicine. Her Wrist Was Swollen and Excruciatingly Painful. Steroids Didn’t Help Much. 2020-12-16T05:00:00Z Writing in Nature, Nett et al.1 shed light on how colchicine, a pharmaceutically and scientifically useful natural product, is biosynthesized in the flame lily Gloriosa superba. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z In 2009 the Food and Drug Administration approved a new version of colchicine, which treats symptoms of gout. How FDA Rules Made a $15 Drug Cost $400 2017-04-05T04:00:00Z The average length of hospital stay was seven days for the colchicine group compared with nine for the other group. Gout drug could reduce Covid hospital stays, new research finds 2021-02-04T05:00:00Z Tardif is planning a study that will investigate the role of colchicine earlier in the disease process, testing whether the drug prevents a first heart attack in 10,000 people with type 2 diabetes. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z Plato used colchicine, an effective plant derivative, to treat his gout and it is still used by most gout sufferers. The EpiPen, a Case Study in Health System Dysfunction 2016-08-23T04:00:00Z Figure 1 | Part of the biosynthetic pathway of colchicine. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z A medical examiner’s office ruled Yoder’s death was a homicide caused by colchicine, a drug used to treat gout. Upstate NY woman charged with killing boss released on bail 2016-06-16T04:00:00Z After an autopsy of Yoder's body, the local medical examiner ruled the women's death a homicide by colchicine poisoning in December. Employee charged with murder in death of New York chiropractor 2016-06-14T04:00:00Z Steinberg thought it might be worth giving Sank a course of colchicine, a well-tolerated drug most commonly used to treat gout. At first, this man thought he had food poisoning. It turned out to be something far worse. 2015-10-26T04:00:00Z No serious side effects were associated with use of colchicine, researchers said, but gastrointestinal issues were reported in about eight percent of patients. Ancient rheumatism drug reduces recurring inflammation around heart 2014-03-30T19:49:28Z The enzymes for the final three steps, in which N-formyldemecolcine is thought to be converted into colchicine, are still unknown. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z The precise mechanism of action of colchicine is uncertain, though the authors point to its high concentration in leukocytes. Colchicine Found Effective in Acute Pericarditis 2013-09-12T15:25:00Z But colchicine doesn't deal with the underlying problem, and White was allergic to the most common anti-uric-acid medicine, allopurinol. Gout, a form of arthritis, is no longer limited to the well-to-do 2011-03-07T23:34:05Z "If the FDA follows its official guidance of a 'one year grace period', Hikma's colchicine is due to be pulled from the market any time now," he said in the September note. FDA to ban unapproved oral colchicine products 2010-09-30T18:57:00Z The rate of recurring pericarditis was nearly halved for those taking colchicine compared with placebo, according to data presented on Sunday at the annual scientific sessions of the American College of Cardiology in Washington. Ancient rheumatism drug reduces recurring inflammation around heart 2014-03-30T19:49:28Z Finding the gene set for colchicine biosynthesis in the total complement of G. superba genes was therefore like finding a needle in a haystack. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z They conclude that “colchicine, when added to conventional antiinflammatory therapy, significantly reduced the rate of incessant or recurrent pericarditis” in patients with a first episode of acute pericarditis. Colchicine Found Effective in Acute Pericarditis 2013-09-12T15:25:00Z Another new product on the market is a version of colchicine called Colcrys. Gout, a form of arthritis, is no longer limited to the well-to-do 2011-03-07T23:34:05Z A spokeswoman said: "Hikma would of course comply if it receives a request or notification to stop selling colchicine." FDA to ban unapproved oral colchicine products 2010-09-30T18:57:00Z Among the women taking colchicine, 97 percent used it during the first 3 months of pregnancy, while 80 percent took the medication throughout pregnancy. Gout drug colchicine safe in pregnancy: study 2010-07-14T20:15:00Z Skilled farm workers hand pollinate the flame lily, Gloriosa superba, which is grown as a source of colchicine.Credit: How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z This latter is the preparation still most generally used, though the presence of veratrine both in the corm and the seeds renders the use of colchicine itself theoretically preferable. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" The price jump for colchicine is especially worrisome to uninsured patients with gout, according to Wayne Grody, a geneticist in Los Angeles. Gout, a form of arthritis, is no longer limited to the well-to-do 2011-03-07T23:34:05Z Seedlings of pecan were available and out of this experience a schedule is submitted that may be of use for other members of this association confronted with particular problems applicable to colchicine techniques. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 In the colchicine group, 4.7 percent of babies were born with major birth defects, such as heart malformations, compared to 3.2 percent of the babies not exposed to colchicine. Gout drug colchicine safe in pregnancy: study 2010-07-14T20:15:00Z This study is a leap forward in our understanding of colchicine biosynthesis. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z At present this otherwise excellent preparation is not standardized, but the suggestion has been made that it should be standardized to contain 0.1% of colchicine. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" It is a compound on the order of colchicine, acting through the somaplasm of the plant. Greener Than You Think The concentration of colchicine need not be exact as in an analytical experiment in chemistry. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 This year we have treated a number of seedlings with colchicine. Northern Nut Growers Association Report of the Proceedings at the Forty-Second Annual Meeting Urbana, Illinois, August 28, 29 and 30, 1951 This will be crucial for achieving the ultimate goal of developing genetically engineered plants that efficiently and sustainably biosynthesize pharmaceuticals such as colchicine. How the flame lily synthesizes a therapeutic natural product 2020-07-21T04:00:00Z The salicylate of colchicine is stable in water and may be given in doses of about one-thirtieth of a grain. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" It should, however, be observed that curare, colchicine, and veratrine are muscle-poisons—that is, act on nerves having some special relation with the muscles, and, therefore, could not be expected to act on Drosera. Insectivorous Plants This is a promising field and whenever such hybrids are discovered, efforts should be made to apply the colchicine technique. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 Pharmacology.—Colchicum or colchicine, when applied to the skin, acts as a powerful irritant, causing local pain and congestion. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" When that is done, colchicine may be found to exhibit a definite chemical interaction with this hitherto undiscovered substance. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" Taken internally, colchicum or colchicine markedly increases the amount of bile poured into the alimentary canal, being amongst the most powerful of known cholagogues. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher" Following the treatment of a growing point with colchicine the outer layer of cells may be doubled by colchicine but the lower layers may remain unchanged. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 There are a number of fundamental research problems in the plant sciences associated with the treatment of plants with colchicine. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 To our knowledge, no investigations of periclinal chimeras have been made with nuts, following treatment with colchicine. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 The local pharmacist or physician is well acquainted with colchicine in the practise of medicine since this drug is a standard for gout. Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting Rockport, Indiana, August 25, 26 and 27, 1952 |
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