| 单词 | purine |
| 例句 | This could only mean that the 3.4 A-thick purine and pyrimidine bases were stacked on top of each other in a direction perpendicular to the helical axis. Double Helix 1968-02-27T00:00:00Z Since the war, Chargaff and his students had been painstakingly analyzing various DNA samples for the relative proportions of their purine and pyrimidine bases. Double Helix 1968-02-27T00:00:00Z Not only did we lack the purine and pyrimidine components, but we had never had the shop put together any phosphorus atoms. Double Helix 1968-02-27T00:00:00Z The resulting backbone would have to show minor in- and-out buckles depending upon whether pairs of purines or pyrimidines were in the center. Double Helix 1968-02-27T00:00:00Z Two irregular sequences of bases could be regularly packed in the center of a helix if a purine always hydrogen-bonded to a pyrimidine. Double Helix 1968-02-27T00:00:00Z The metal purine and pyrimidine models, needed for systematically checking all the conceivable hydrogen-bonding possibilities, had not been finished on time. Double Helix 1968-02-27T00:00:00Z When he said no, my morale skyrocketed, for I suspected that we now had the answer to the riddle of why the number of purine residues exactly equaled the number of pyrimidine residues. Double Helix 1968-02-27T00:00:00Z This had the important consequence that a given chain could contain both purines and pyrimidines. Double Helix 1968-02-27T00:00:00Z Each got a quick, concise lecture from Francis, during the second of which I wandered down to see if the shop could be speeded up to produce the purines and pyrimidines later that afternoon. Double Helix 1968-02-27T00:00:00Z After saying that I was going to ask a Cavendish machinist to make models of the purines and pyrimidines, I remained silent, waiting for Bragg’s thoughts to congeal. Double Helix 1968-02-27T00:00:00Z Neither phosphorus atoms nor the purine and pyrimidine bases were on hand. Double Helix 1968-02-27T00:00:00Z “Some people are just genetically able to process those purines in our diet, which is a breakdown product of various foods, better than others,” Bauer said. This new 40-foot mural wants to educate you about a misunderstood disease 2023-08-21T04:00:00Z These bases form complementary base pairs consisting of one purine and one pyrimidine, with adenine pairing with thymine, and cytosine with guanine. Chemistry 2019-02-14T00:00:00Z The purines have a double ring structure with a six-membered ring fused to a five-membered ring. Biology for AP Courses 2022-06-09T00:00:00Z A purine is a nitrogen-containing molecule with a double ring structure, which accommodates several nitrogen atoms. Anatomy and Physiology 2013-06-19T00:00:00Z The foods most likely to contribute to these inner stalagmites are high in the chemical compound purine, among them venison and foie gras, pheasant and scallops, goose and caviar. Once the Disease of Gluttonous Aristocrats, Gout Is Now Tormenting the Masses 2020-11-13T05:00:00Z In Xu and co-workers’ synthetic pathway, a UV-induced chemical reduction occurs that leads to the strikingly selective destruction of these unwanted by-products, ultimately producing only the biologically relevant isomers of the purines. How DNA and RNA subunits might have formed to make the first genetic alphabet 2020-06-02T04:00:00Z Elion focused on purines, which are key components of DNA and which contain oxygen. Chemistry 2019-02-14T00:00:00Z Base pairing takes place between a purine and pyrimidine; namely, A pairs with T and G pairs with C. Adenine and thymine are complementary base pairs, and cytosine and guanine are also complementary base pairs. Biology for AP Courses 2022-06-09T00:00:00Z The trouble was that Sutherland's and Carell's routes to pyrimidines and purines required different reaction conditions, making it difficult to imagine how they could have taken place side by side. How an ancient cataclysm may have jump-started life on Earth 2019-01-10T05:00:00Z Brewer’s yeast is high in purines, so indulging in something as populist as beer is another risk. Once the Disease of Gluttonous Aristocrats, Gout Is Now Tormenting the Masses 2020-11-13T05:00:00Z This involves compounds circulating in the blood, known as purines, which command cells to halt their normal activities and brace for an imminent viral attack. A drug used to treat sleeping sickness may also help with autism 2017-05-28T04:00:00Z Treating the animals with allopurinol, an inhibitor of purine metabolism, eased the colitis. Microbiome: Yeast worsens gut disorder : Nature : Nature Research 2017-03-14T04:00:00Z Only the pairing between a purine and pyrimidine can explain the uniform diameter. Biology for AP Courses 2022-06-09T00:00:00Z It turns out that gaining electrons enables the metals to then carry out a final step in synthesizing purines. How an ancient cataclysm may have jump-started life on Earth 2019-01-10T05:00:00Z That’s in part because the process produced only tiny amounts of the purines so vital for life. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z Intracellular bodies composed of purine biosynthetic enzymes exhibit an mTOR-mediated association with mitochondria. Spatial colocalization and functional link of purinosomes with mitochondria | Science 2016-02-11T05:00:00Z Urate is formed when chemicals called purines -- found in food -- are broken down in the body. High Uric-Acid Levels, Lower Risk of Parkinson's? 2016-01-13T05:00:00Z Transition substitution refers to a purine or pyrimidine being replaced by a base of the same kind; for example, a purine such as adenine may be replaced by the purine guanine. Biology for AP Courses 2022-06-09T00:00:00Z Most of the urine samples taken from patients contain high levels of uric acid, a waste product of a protein called purine. Clues Emerge in the Fight against a Mysterious Killer of Central American Farmers 2015-11-16T05:00:00Z “People have been looking for synthetic routes to making purines for 40 years,” Carell says. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z Intracellular bodies composed of purine biosynthetic enzymes exhibit an mTOR-mediated association with mitochondria. Spatial colocalization and functional link of purinosomes with mitochondria | Science 2016-02-11T05:00:00Z Limit intake of red meat and seafood. Red meat – including beef, pork, lamb and game meats, organ meats and fish and seafood – are the highest purine proteins. How to Eat to Control Gout 2015-01-06T05:00:00Z Transversion substitution refers to a purine being replaced by a pyrimidine, or vice versa; for example, cytosine, a pyrimidine, is replaced by adenine, a purine. Biology for AP Courses 2022-06-09T00:00:00Z The increased risk was seen even among patients with low purine intake in the 24 hours prior to an attack, the researchers found. Gout Attacks More Common at Night: Study 2014-12-11T05:00:00Z So they decided to look into whether early Earth conditions could have given rise to FaPys, and thus purines. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z These are important and widespread substances: ATP, a molecule that shuttles energy around cells, is a purine; so are half the “genetic letters” in DNA. Rain mouse 2014-06-19T04:00:00Z Uric acid is a waste product which is formed when the body breaks down chemicals in its cells known as purines. Gout: Why I don't find it funny at all 2014-01-02T00:57:09Z A purine always pairs with a pyrimidine; A pairs with T, and G pairs with C. One turn of the helix has ten base pairs. Biology for AP Courses 2022-06-09T00:00:00Z Certain foods are high in purines, including organ meat, seafood and alcohol. Gout Attacks More Common at Night: Study 2014-12-11T05:00:00Z But this route hasn’t been shown to give rise to adenine or guanine, RNA’s purine building blocks. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z For instance, the researchers suggest that one bacterial lineage synthesizes purine bases — building blocks of DNA and RNA — using enzymes previously thought to exist only in archaea. Single-Cell Sequencing Reveals Genomes of More than 200 Unusual Microbes 2013-07-15T21:54:56.690Z When a cell was deprived of purines, the enzymes grouped together in a cluster, which the team called the 'purinosome'. Cell biology: The new cell anatomy 2011-11-30T18:20:28.260Z Uric acid is a compound similar to purines found in nucleic acids. Biology for AP Courses 2022-06-09T00:00:00Z Despite its hydrolytic instability, that arsenate must be maintained for many steps as the purine and pyrimidine rings are forged. [Technical Comment] Comment on ?A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus? 2011-06-02T18:25:14.937Z Benner agrees that the newly suggested purine synthesis is a “major step forward” for the field. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z The first is hyperuricemia, the buildup of uric acid in the bloodstream, which happens when the body breaks down purines - DNA building blocks that are particularly high in certain meats, shellfish and beer. Gout, a form of arthritis, is no longer limited to the well-to-do 2011-03-07T23:34:05Z Benkovic's group found evidence that this clustering does occur in enzymes that produce a precursor of purine nucleotides, which are components of DNA and RNA. Cell biology: The new cell anatomy 2011-11-30T18:20:28.260Z For example, a certain purine can only pair with a certain pyrimidine. Biology for AP Courses 2022-06-09T00:00:00Z In the course of this study, Emil Fischer established uric acid and a number of its derivatives as having the elementary skeleton of what he called “pure uric acid,” abbreviated to purine. History of Phosphorus And much to Carell’s delight, the lone amine that stayed reactive was precisely the one that reacts to form a purine. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z The level of uric acid in the bloodstream depends on how fast the purines are broken down and how fast the uric acid is flushed through our kidneys. Gout, a form of arthritis, is no longer limited to the well-to-do 2011-03-07T23:34:05Z This is a group of compounds, widely distributed in both plant and animal tissues, all of which are derivatives of the compound known as purine, C5H4N4. The Chemistry of Plant Life Bonds in the purine and pyrimidine rings of nucleic acids are broken by high-energy uv radiation. Biology for AP Courses 2022-06-09T00:00:00Z FUNK, C.: The action of certain purine and pyrimidine derivatives. The Vitamine Manual But even if it’s correct, he says, the chemical conditions that gave rise to the purines still don’t match those that Sutherland’s group suggests may have led to the pyrimidines. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z They are not so directly related to protein metabolism as are the other purine bases. The Chemistry of Plant Life In purine itself, the four hydrogen atoms are attached in the 2, 6, 7, and 8 positions. The Chemistry of Plant Life The purine bases, other than the three mentioned in the preceding paragraph, are undoubtedly intermediate products in protein metabolism. The Chemistry of Plant Life They are nitrogenous bases, similar to, but somewhat simpler than, the purine bases. The Chemistry of Plant Life Once the bonds have formed, products of those reactions then eagerly react with sugars to create large quantities of purines. ‘RNA world’ inches closer to explaining origins of life 2016-05-12T04:00:00Z The nucleic acids are complex compounds consisting of a carbohydrate, phosphoric acid, two purine bases, and two pyrimidine bases. The Chemistry of Plant Life With this understanding, reference to the numbered nucleus formula above will make plain the structure of all of the purine bases which are included in the following list: Hypoxanthine, C5H4N4O, = 6-monoxypurine.Xanthine, The Chemistry of Plant Life |
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