| 单词 | Plavix |
| 例句 | Plavix is prescribed to prevent strokes and heart attacks. Bristol-Myers, Sanofi ordered to pay Hawaii $834 million over Plavix warning label 2021-02-15T05:00:00Z Most often, patients are given aspirin and Plavix, known generically as clopidogrel. Factbox: Bernie Sanders heart procedure common, usually with fast recovery 2019-10-02T04:00:00Z But she did not have the $300 a month to pay for Plavix — a blood thinner she needed because of a stent put in her heart — so she stopped. With the Affordable Care Act’s future in doubt, evidence grows that it has saved lives 2019-09-29T04:00:00Z The companies were accused of deception by marketing Plavix as superior to aspirin with a much higher price. W.Va. settles complaint with drug makers over blood thinner 2019-03-21T04:00:00Z Compared with an older blood thinner called Plavix, ticagrelor lowers the risk of recurrent heart attacks by about 2 percent. With drugs, how do we base their medical value vs. out-of-pocket cost? 2018-11-09T05:00:00Z Food and Drug Administration in 2010 issued a new Plavix warning label to reflect that information. Bristol-Myers, Sanofi ordered to pay Hawaii $834 million over Plavix warning label 2021-02-15T05:00:00Z Brilinta is admittedly more effective than Plavix — by all of 2 percentage points. Can Doctors Choose Between Saving Lives and Saving a Fortune? 2018-04-03T04:00:00Z But the deal fell apart due to resistance from federal and state antitrust regulators and Apotex flooded the U.S. market with inexpensive Plavix generics, hurting sales of the name-brand drug. Apotex Founder Barry Sherman Was Driven, Generous...and Litigious 2017-12-19T05:00:00Z In recent years, Mr. Sherman found himself and his company in the epicenter of a legal uproar in the U.S. after Apotex launched a cheaper, generic version of Plavix, a best-selling blood thinner. Police Say Deaths of Apotex Founder and Wife Being Investigated as Homicides 2017-12-18T05:00:00Z Mr. Sherman found himself and his company in the epicenter of a legal uproar in the U.S. in recent years, after Apotex launched a cheaper, generic version of Plavix, a best-selling blood thinner. Police Probe Deaths of Canadian Billionaire and Wife 2017-12-16T05:00:00Z “The non-residents were not prescribed Plavix in California, did not purchase Plavix in California, did not ingest Plavix in California, and were not injured by Plavix in California,” Alito said in his majority opinion. Supreme Court tightens rules on class-action lawsuits 2017-06-19T04:00:00Z In a yearlong trial of 18,600 patients, 10 percent died from vascular causes, heart attack or stroke on Brilinta, while about 12 percent did on Plavix. Can Doctors Choose Between Saving Lives and Saving a Fortune? 2018-04-03T04:00:00Z "Often you would want to use a blood thinner, which would be an anti-platelet agent like aspirin or Plavix." Is it Alzheimer's or Another Type of Dementia? 2016-09-14T04:00:00Z The same receptor is also present on platelets and is one of the targets of blood-thinning drugs such as Plavix, the researchers noted. Immune Cells Repair Damage to Blood-Brain Barrier in Mice 2016-01-12T05:00:00Z Rather than focusing on a particular drug or set of drugs, it included a wide variety, as diverse as painkillers and the anti-clotting drug Plavix. Genetic Testing Case Highlights the Field’s Hope and Hype 2015-06-24T04:00:00Z Cases of serious bleeding, while still rare, were more common among users who took Kengreal than Plavix, the FDA said. Anti-Clotting Drug Approved For Angioplasty 2015-06-22T04:00:00Z The study excluded people on that drug, also known as Plavix. Common heartburn medications linked to greater risk of heart attack 2015-06-10T04:00:00Z Some research has also suggested the medications can interact with the clot-preventing drug Plavix, lowering its effectiveness. Popular Heartburn Meds Linked to Higher Risk of Heart Attack 2015-06-10T04:00:00Z Recent examples include cholesterol fighter Lipitor, blood thinner Plavix and blood pressure drug Diovan. AARP survey: Many generic medicine prices have risen sharply 2015-05-28T04:00:00Z In the current study, about 24 percent of the stent patients suffered a stroke within 30 days compared to less than 10 percent of those treated with Plavix and aspirin, the researchers found. Stents Meant to Prevent Stroke May Actually Boost Risk 2015-03-24T04:00:00Z All stayed on aspirin for another 18 months, and half stayed on Plavix or Effient, too. Heart stents may require longer blood thinner use 2014-11-16T05:00:00Z Warfarin and Plavix, along with aspirin, are some of the most commonly used medications for atrial fibrillation. Could Too Much Medication for Irregular Heartbeat Raise Dementia Risk? 2014-11-16T05:00:00Z The study, dubbed PLATO, showed that patients taking Brilinta instead of competing drug Plavix were less likely to experience various heart-related problems, including heart attack, stroke and death. AstraZeneca says DOJ closes probe into drug trial 2014-08-19T04:00:00Z Demonstrating Brilinta's unique value in multiple groups of heart patients is crucial for commercial success, since the product is competing with Sanofi SA's now off-patent medicine Plavix, which is available as a cheap generic. U.S. clears AstraZeneca over heart drug trial 2014-08-19T04:00:00Z Zontivity is expected to be used in addition to standard therapy given to prevent a second heart attack - typically aspirin and the clot preventer Plavix. U.S. FDA approves Merck blood clot preventer 2014-05-08T22:29:03Z Standard therapy to prevent a second episode often includes treatment with aspirin and Plavix. Merck's anti-blood clot drug should be approved: FDA review 2014-01-13T14:57:03Z For example, in 2010 it was discovered that the popular heart-attack-prevention drug Plavix is less effective for nearly one in three patients because of variances in their metabolisms. Animal testing is on its way out, study says 2013-12-06T13:36:00Z In addition, he takes amiodarone and Plavix for his heart. Sugar-solution injections for osteoarthritis 2013-06-05T18:23:58Z It did not provide details, saying only that the investigation centered on "the variability of response to Plavix." US probes Sanofi over blockbuster drug Plavix 2013-03-11T19:12:08Z After all, Plavix was for many years the second-best-selling drug in the world. 2012 In Review: A Bad Year For Conventional Wisdom 2012-12-24T14:00:07Z Paul M. Bisaro, chief executive of Watson, said when blockbusters like Plavix or Lipitor lost patent protection, they got a lot of attention. Generic Drug Makers Facing Squeeze on Revenue 2012-12-05T06:36:02Z That decline was mainly because of the patent expiration of several blockbuster drugs, like Lipitor and Plavix, which opened the market for generic competitors. Cost of Brand-Name Prescription Medicines Soaring 2012-11-29T02:35:10Z In 2008, a study found that a proton pump inhibitor may weaken the heart-protective effect of the blood thinner Plavix in patients taking both medications. 8 Common Digestive Problems and How to End Them 2012-09-06T13:15:00Z Justice Department is investigating drug maker Sanofi's disclosures to the Food and Drug Administration about different responses to its blockbuster blood thinner Plavix. US probes Sanofi over blockbuster drug Plavix 2013-03-11T19:12:08Z Bristol's Plavix revenue, nearly all from U.S. sales, plummeted 60 percent to $741 million in the April-June quarter, even the generics were only available for half that time. New coupons aim to keep people off generic drugs 2012-08-20T20:46:05Z Sanofi’s profitable drugs, such as the blood thinner Plavix, are losing ground to generic medicines. Sanofi's Shock Therapy Enrages the French 2012-08-09T22:46:02Z It is searching for fresh sources of revenue because its top-selling product, the blood thinner Plavix, now faces competition in the United States from cheaper generic drugs. Bristol-Myers suspends hepatitis C treatment study 2012-08-02T18:46:04Z It also sells the world's second-best-selling drug, the blood thinner Plavix, but revenue from that is expected to plunge due to competition from cheaper generic drugs in the U.S. market. Bristol-Myers suspends hepatitis C treatment study 2012-08-02T12:43:08Z Before it got U.S. generic competition last May, Plavix was the No. 2 drug in the world by revenue, with annual sales of around $9 billion in 2011. US probes Sanofi over blockbuster drug Plavix 2013-03-11T19:12:08Z Generic Plavix, for example, is called clopidogrel bisulfate. New coupons aim to keep people off generic drugs 2012-08-20T20:46:05Z That would reflect a decline of 12 percent to 17 percent from 2011, when Plavix held sway as the world's second-biggest-selling medicine. Drugmakers Lilly, Bristol weather patent cliffs 2012-07-25T16:50:52Z Plavix sales plummeted 60 percent to $741 million in the second quarter after several generic rivals debuted in May. Bristol-Myers suspends hepatitis C treatment study 2012-08-02T18:46:04Z The new study will compare AstraZeneca's medicine, which is currently only approved for patients with acute coronary syndromes, against its older rival Plavix. AstraZeneca starts new study of heart drug Brilinta 2012-07-17T06:13:47Z In order to work effectively, Plavix must be broken down by a particular liver enzyme. US probes Sanofi over blockbuster drug Plavix 2013-03-11T19:12:08Z The medicines include staples in the American medicine cabinet - cholesterol fighter Lipitor, blood thinner Plavix and blood pressure drug Diovan - along with drugs for depression and breast cancer. New coupons aim to keep people off generic drugs 2012-08-20T20:46:05Z At least the Plavix case will use the DNA to address the same illness for which it was donated. Is Future-Use DNA Sampling Ethical? 2012-07-13T14:45:09.280Z The brunt will be felt this year, with at least nine major drugs — including Plavix, Seroquel and Singulair — losing their patent protections in the United States. Drug Makers’ Growth Seen in Emerging Markets 2012-07-12T14:43:41Z But Plavix is different because the company that won that right, the Canadian drug maker Apotex, forfeited its exclusive period after it flooded the market in 2006 with unauthorized generic versions of the drug. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z Plavix sales before cheap generics hit.Bottom of the pack is AstraZeneca, trading on just 7 times this year's expected earnings. Abbott's Humira set to become world's top-selling drug 2012-04-11T13:50:00Z The agreement is the biggest among 18 made by Bristol since 2007 in a strategy aimed at overcoming sales declines after its $6.7 billion-a-year blood thinner Plavix loses patent protection this year. Bristol Buys Inhibitex for $2.5 Billion to Compete in Hepatitis 2012-01-08T21:39:25Z They’re likely due to the drug Plavix, a trade-off for preventing clots. Is Future-Use DNA Sampling Ethical? 2012-07-13T14:45:09.280Z Bristol made 17 acquisitions over four years with Levin, seeking to diversify its drug portfolio before facing revenue erosion as the company’s top-selling drugs, led by the blood thinner Plavix, lose U.S. patent protection. Bristol-Myers Agrees to Acquire Inhibitex for $2.5 Billion 2012-01-08T09:47:01Z Before Plavix arrived in 1997, aspirin was the standard treatment for preventing blood clots that led to heart attacks and stroke. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z The plan was created as a way to diversify the company’s drug portfolio as it was facing revenue decreases from Plavix, a blood thinner with $6.67 billion in 2010 sales, and other top- selling drugs. Bristol’s Acquisition Plans Won’t Change With Executive’s Loss 2012-01-02T18:22:02Z Not bad considering the fact that investors are bracing for the patent expiration of Plavix, the blood-thinner Bristol shares with French drug giant Sanofi, next year. The Best Big Drug Company Of 2011 2011-12-26T20:55:08Z The original Plavix genetic test identified mutations in the CYP2C19 gene. Is Future-Use DNA Sampling Ethical? 2012-07-13T14:45:09.280Z Plavix prevents blood clots by blocking platelets from binding together in the blood. High blood thinner doses overcome genetic barrier 2011-11-16T21:06:51Z Combining aspirin with Plavix, though, “tremendously improved” the results, Dr. Nissen said. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z Q: How are you going to deliver on your promise to produce 5 percent revenue growth through 2015, with key products such as Plavix and Avapro getting U.S. generic competition next spring? 3 years in, Sanofi CEO has transformed drugmaker 2011-10-28T13:16:20Z He already views drugs about to lose patent protection like Plavix as "discontinued business". Sanofi CEO says drug industry undervalued 2011-09-20T11:31:37Z On June 29, the University of Florida Academic Health Center announced that it would use the wider genetic test to screen all cardiac catheterization patients for response to Plavix. Is Future-Use DNA Sampling Ethical? 2012-07-13T14:45:09.280Z The system works, the industry trade group said, noting that 17 of 23 expected generic drug introductions this year, like Lipitor and Plavix, will be the result of patent settlements. F.T.C. Criticizes Agreements That Delay Generic Drugs 2011-09-01T00:09:55Z “We expect a rapid, precipitous and material decline in Plavix net sales,” company officials wrote in the 2011 annual report. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z Sales of Plavix and Avapro will fall further next year, when their U.S. patents expire. 3 years in, Sanofi CEO has transformed drugmaker 2011-10-28T13:16:20Z Both companies stand to benefit as blockbuster drugs like Lipitor, Plavix and others lose patent protection over the next few years. Drug dispensing co Omnicare offers to buy PharMerica in deal valued at about $457 million 2011-08-23T18:40:11Z In the meantime, once Lipitor and Plavix get generic competition his copayments will plunge. Drug prices to plummet in wave of expiring patents 2011-07-25T17:46:04Z The company, which sells blockbuster blood thinner Plavix, still beat Wall Street expectations, and it increased its earnings-per-share forecast for 2011 by 8 to 10 cents. Drugmaker Bristol-Myers posts 3 pct dip in 2Q profit on higher costs, taxes, but sales jump 2011-07-28T13:59:29Z Analysts expect the price of generic alternatives to be substantially lower than brand-name Plavix. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z Bristol-Myers has been developing new medicines and divesting nondrug businesses as it prepares for U.S. competition to Plavix, whose sales topped analysts’ estimates with a 15 percent gain in the quarter. Bristol-Myers Raises Forecast as Revenue Exceeds Estimates 2011-07-28T11:53:04Z Plavix was the world’s second- best selling drug. Meda at 15-Month High Still May Rise 30% in Drug Deal: Real M&A 2011-07-28T04:45:03Z Another side effect of Brilinta, but not Plavix, is difficulty breathing in some cases. AstraZeneca Anticlotting Drug Wins Approval 2011-07-21T01:43:18Z That’s the first full year after generic competition starts slashing Plavix revenue. Drugmaker Bristol-Myers posts 3 pct dip in 2Q profit on higher costs, taxes, but sales jump 2011-07-28T13:59:29Z A spokeswoman for the large drug distributor Cardinal Health said the company planned to begin shipping generic Plavix on Friday. Clot-Fighting Drug Plavix Set to Lose Patent Protection 2012-05-17T14:53:01Z After installing a stent near my heart, my doctor said no changes were needed in my list of medications, even though I would be mixing Nexium with Plavix for the next year. People's Pharmacy: the benefits and risks of vitamin D 2011-07-13T21:57:03Z Plavix, according to a new analysis of a study. AstraZeneca, Northumbrian Water, TomTom: Europe Equity Preview 2011-06-28T06:33:51Z It is faster-acting than Plavix and reversible if the patient bleeds. AstraZeneca Anticlotting Drug Wins Approval 2011-07-21T01:43:18Z They found that adding Plavix to aspirin produced further benefit, while the beta-blocker metoprolol did not. Special report: Big Pharma's global guinea pigs 2011-05-06T07:17:51Z Dolan made a deal to delay sales of cheaper Plavix copies by Apotex Inc., violating terms of a deferred prosecution agreement. Drugmaker Patent Accords Delaying Generics Up 63%, FTC Says 2011-05-03T21:48:01Z Q: You might wish to tell readers to beware taking both Plavix and Nexium. People's Pharmacy: the benefits and risks of vitamin D 2011-07-13T21:57:03Z The French drugmaker is also suffering from generic competition to best-selling products such as the blood thinner Plavix. Sanofi Profit Drops on Generics, Pandemic Flu End 2011-04-28T05:37:03Z But the approved label — critical to marketing the drug — also says Brilinta was proved superior to Plavix in reducing heart attacks and deaths from cardiovascular causes. AstraZeneca Anticlotting Drug Wins Approval 2011-07-21T01:43:18Z IMS Health estimates that $25.4 billion in U.S. drug sales are at risk of generic competition this year as patents expire on iconic brands like Lipitor and Plavix. Branded drug prices soar as generic pressure rises 2011-03-23T15:46:59Z Sales of the Lovenox and Plavix blood thinners sank 23 percent and 11 percent, respectively, in the fourth quarter, the company said today. Sanofi’s Genzyme Talks ‘Progressing;’ Earnings to Drop 2011-02-09T06:47:02Z Some studies suggest the acid-suppressor will interfere with the effectiveness of Plavix or even aspirin. People's Pharmacy: the benefits and risks of vitamin D 2011-07-13T21:57:03Z The FDA requested a new analysis from the company's 18,000-patient study comparing its drug to Plavix, the third-best-selling drug in the United States last year. AstraZeneca abandons work on prostate cancer drug 2011-02-07T14:47:51Z In a note to investors, Timothy Anderson, analyst for Bernstein Research, said he continued to believe commercial prospects would be limited because of the pending lower prices for Plavix. AstraZeneca Anticlotting Drug Wins Approval 2011-07-21T01:43:18Z That merger created a powerhouse with blockbusters such as anti-clotting drug Plavix, the world's second best-selling prescribed medicine. UPDATE 1-Sanofi, Genzyme takeover talks enter final stretch 2011-02-07T09:04:27Z Plavix and aspirin have been shown to increase the risk of bleeding. Merck Blood Thinner Studies Halted in Select Patients 2011-01-13T20:39:01Z The company is seeking ways to replace revenue it will lose as some of its biggest- selling products, such as the blood thinner Plavix and the cancer drug Taxotere, face competition from generic medicines. Sanofi, Genzyme Chiefs Say Buyout Talks Advancing on Special Fee 2011-01-12T01:08:01Z Sanofi is seeking acquisitions to replace revenue the company is losing as some of its biggest-selling products, such as the blood thinner Plavix and the cancer drug Taxotere, face competition from generic medicines. Sanofi Sees ‘Significant Differences’ in Genzyme Takeover Talks 2011-01-09T23:02:02Z Some patients respond to Brilinta who do not respond to Plavix, for genetic reasons. AstraZeneca Anticlotting Drug Wins Approval 2011-07-21T01:43:18Z Marino told the judge he is taking beta blockers and the blood thinner Plavix. Alleged Gambino Organized Crime Figure Pleads Guilty 2010-12-21T23:32:36Z But a study published in August and sponsored by Sanofi and BMS contradicted the idea that people with a certain genetic make-up did not benefit from Plavix. New gene variation predicts response to Plavix 2010-12-19T18:05:40Z In an international clinical trial, Brilinta proved superior overall to Plavix – one of the world’s best selling drugs – in preventing heart attacks, strokes and deaths from cardiovascular causes. Prescriptions: This Week's Health Industry News 2010-12-13T13:51:00Z Expectations appear uniform that approval with a strong label is the most likely outcome, including a superiority claim versus Plavix. AstraZeneca rises despite revealing US healthcare reform hit, while FTSE continues to fly 2010-12-01T12:03:00Z There's also concern the medication may interfere with a heart drug, Plavix. Pills put under the microscope 2010-10-11T17:59:00Z The combination of Plavix and Prilosec used in the study is not commercially available; combining the heart drug and the over-the-counter version of the antacid might yield different results. Quick Study: Antacid does not seem to inhibit effects of heart drug 2010-10-11T21:04:00Z Plavix loses patent protection in 2012, and generic competition will slash its sales. Bristol-Myers to cut about 840 jobs worldwide 2010-09-23T20:39:00Z Some people are not able to convert Plavix to its active form, and the researchers said blacks may be more prone to this problem. Blacks more prone to blood clots after stents 2010-08-30T20:02:00Z A third study, sponsored by Sanofi and Bristol, contradicted the idea that people with a certain genetic make-up don't benefit from Plavix. Gene testing war looms for AstraZeneca heart drug 2010-08-29T14:19:00Z His own review, published in April, found no evidence that the drugs interfere with Plavix, for example. Pills put under the microscope 2010-10-11T17:59:00Z It is viewed as a key growth driver for Sanofi to see it through the years when patents expire on blockbusters like cancer treatment Taxotere and blood thinner Plavix. European guidelines back use of Sanofi's Multaq 2010-08-29T08:49:00Z Still on blood thinners Coumadin and Plavix, Vickers said he's been told he'll stop taking them in time to race next season. NASCAR driver Brian Vickers: Had heart surgery for blood clots 2010-08-21T20:55:00Z It will urge doctors to test patients taking a rival drug, Plavix, to see if it is working. Eli Lilly Pitches Blood Test to Aid Sales of Blood Thinner 2010-07-12T19:37:00Z The stakes are high because Plavix is the world's second biggest drug, with sales last year of more than $9.5 billion. Gene testing war looms for AstraZeneca heart drug 2010-08-29T14:19:00Z The results suggest that better awareness of Plavix's benefits in such high-risk patients could have "considerable clinical impact," the researchers wrote. Plavix benefit found in heart failure patients 2010-03-22T21:01:00Z Both Pathway Genomics and 23andMe now test for genetic variations that determine whether certain medications, like the anti-clotting drugs Plavix and warfarin, will work for people or cause side effects. Consumers Slow to Embrace the Age of Genomics 2010-03-20T04:10:00Z The new language will "warn about reduced effectiveness in patients who are poor metabolizers of Plavix," the FDA said in a notice on its website. Plavix gets new FDA warning 2010-03-12T21:01:00Z Effient was better at preventing heart attacks and strokes than Plavix in its main clinical trial, but it also caused more bleeding incidents, including fatal ones. Eli Lilly Pitches Blood Test to Aid Sales of Blood Thinner 2010-07-12T19:37:00Z The link between Plavix response rates and genetics hit the headlines in March, when the U.S. Gene testing war looms for AstraZeneca heart drug 2010-08-29T14:19:00Z They looked at two groups with heart failure -- one receiving Plavix and one not, and two without heart failure -- one receiving Plavix and one not. Plavix benefit found in heart failure patients 2010-03-22T21:01:00Z Bristol-Myers, the maker of the blockbuster blood thinner Plavix, announced the changes Tuesday after the stock market closed. Bristol-Myers Squibb Promotes President to Chief Executive 2010-03-03T02:18:00Z Poor metabolizers are people whose bodies do not effectively convert Plavix to its active form. Plavix gets new FDA warning 2010-03-12T21:01:00Z “It’s a challenge to sell to doctors satisfied with Plavix,” he added. 2010-02-13T01:59:00Z Sanofi is already facing generic competition for the blood thinner Plavix in Europe and the cancer drug Eloxatin in the United States. 2010-02-11T06:00:00Z In patients without heart failure, Plavix had no effect on death rates, which were just over 9 percent in both groups, but its effect in the high-risk groups was significant. Plavix benefit found in heart failure patients 2010-03-22T21:01:00Z Plavix is the second-best selling drug in the world. Plavix gets new FDA warning 2010-03-12T21:01:00Z An estimated 2 percent to 14 percent of the population are poor metabolizers of Plavix, the FDA said. Plavix gets new FDA warning 2010-03-12T21:01:00Z Dr. Ong, who is not involved with any of the drug companies, said Plavix worked well and was time-tested, while Effient’s higher risk of bleeding “kind of dampens the enthusiasm for it.” 2010-02-13T01:59:00Z Plavix reduces the risk of heart attack, unstable angina, stroke, and cardiovascular death in patients with heart disease by making platelets less likely to form blood clots. Plavix gets new FDA warning 2010-03-12T21:01:00Z On one side, Plavix, approved in 1997, will be sold generically starting late next year. 2010-02-13T01:59:00Z But when it goes generic next year, Plavix may be expected to fall in price by as much as 90 percent, said Tim Heady, chief executive of UnitedHealth Pharmaceutical Solutions, a pharmacy benefits company. 2010-02-13T01:59:00Z "Patients should continue taking Plavix unless told to do otherwise by their healthcare professional," the company said in a statement. Plavix gets new FDA warning 2010-03-12T21:01:00Z |
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