| 单词 | mutagenesis |
| 例句 | "Xiangyu's comprehensive study of the structure highlights the advantage that a targeted, structurally guided approach has over large and costly random mutagenesis screening." Tiny CRISPR tool could help shred viruses 2023-09-27T04:00:00Z “That is what we term lethal mutagenesis,” he adds. How Antiviral Pill Molnupiravir Shot Ahead in the COVID Drug Hunt 2021-10-12T04:00:00Z Dr. Wolt said that the only way to escape these contradictions would be for government regulators to stop focusing on mutagenesis, recombinant DNA, Crispr and other methods for making new crops. What Is a Genetically Modified Crop? A European Ruling Sows Confusion 2018-07-27T04:00:00Z The court also asserted that gene-editing techniques “make it possible to produce genetically modified varieties at a rate out of all proportion to those resulting from the application of conventional methods of mutagenesis.” European court ruling raises hurdles for CRISPR crops 2018-07-25T04:00:00Z The directive provides an exemption to organisms whose genomes were modified using mutagenesis techniques, such as irradiation, which introduces changes to an organism’s DNA but doesn’t add foreign DNA.. CRISPR plants now subject to tough GM laws in Europe 2018-07-24T04:00:00Z The case before the ECJ was brought by a group of French agricultural associations that want the existing EU exemption for plant varieties obtained via mutagenesis to be restricted to long-standing conventional techniques. Battle lines drawn as EU court weighs fate of gene-edited crops 2018-07-20T04:00:00Z These structure-based mutagenesis studies provide insight to the machineries involved in ion permeation through the channel and force gating. Force-activated ion channels in close-up 2018-02-11T05:00:00Z Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes 2018-01-23T05:00:00Z Maurice Moloney, CEO of the Global Institute for Food Security in Saskatoon, Canada, called it “logically absurd” that gene editing was riskier than the random mutagenesis used in conventional breeding. European court ruling raises hurdles for CRISPR crops 2018-07-25T04:00:00Z Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z The biotech industry argues that much of gene editing is effectively little different to the mutagenesis that occurs naturally or is induced by radiation - a standard plant breeding method since the 1950s. Battle lines drawn as EU court weighs fate of gene-edited crops 2018-07-20T04:00:00Z Breeders argue that gene editing is a type of mutagenesis because it involves changes to single nucleotides. Europe court suggests relaxed gene-editing rules 2018-01-18T05:00:00Z Reducing codon redundancy and screening effort of combinatorial protein libraries created by saturation mutagenesis. Genetically programmed chiral organoborane synthesis 2017-11-28T05:00:00Z French non-governmental organizations and trade unions had called on the French state to regulate organisms created through all methods of mutagenesis, including classical methods. Gene editing in legal limbo in Europe 2017-02-21T05:00:00Z Through a combination of rational design and random mutagenesis, they created dozens of bright fluorescent proteins of various colours based on GFP. Roger Yonchien Tsien (1952-2016) : Nature : Nature Research 2016-10-11T04:00:00Z Chance leads to discoveries, and mutagenesis is a way to enhance one's chances of finding a surprise. Q&A: Chance encounters : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Because they target a selected region of the genome, these strategies abrogate the risk of insertional mutagenesis and poorly controlled transgene expression that is associated with conventional gene-replacement strategies. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z Another common technique for creating new plant varieties, which originated about a century ago, is radiation mutagenesis–subjecting seeds to radiation or toxic chemicals to scramble their DNA and create mutants. Chipotle: The Strangest Restaurant Menu Ever 2015-04-27T04:00:00Z Nor is mutagenesis, a process in which mutations and variations are induced by radiation or chemicals. The Problem with G.M.O. Labels 2014-08-20T04:00:00Z First author 'A. L. Nighter' and colleagues reported subjecting a group of “graduate student clones” to “several rounds of random mutagenesis followed by selection on minimal money media”. Beef's big impact on Earth : Nature : Nature Publishing Group 2014-07-29T04:00:00Z We used chemically induced random mutagenesis of the mouse genome to identify genes and their functions. Q&A: Chance encounters : Nature : Nature Publishing Group 2015-10-20T04:00:00Z And many consumers believe, despite evidence to the contrary, that the foods pose more health risks than those grown through conventional breeding and mutagenesis. Not on the label 2014-05-20T04:00:00Z Wide-cross hybridizations and radiation-induced mutagenesis represent far more drastic “tinkering with Nature” and create far greater attendant uncertainty about the results than the modern molecular techniques. Chipotle: The Strangest Restaurant Menu Ever 2015-04-27T04:00:00Z Tumors with low RPS were associated with greater mutagenesis, adverse clinical features, and inferior patient survival rates, suggesting that HR suppression contributes to the genomic instability that fuels malignant progression. [Research Articles] DNA Repair Pathway Gene Expression Score Correlates with Repair Proficiency and Tumor Sensitivity to Chemotherapy 2014-03-26T19:25:09.530Z The recurrent tumors in many of the TMZ-treated patients bore the signature of TMZ-induced mutagenesis and appeared to follow an evolutionary path to high-grade glioma distinct from that in untreated patients. [Report] Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma 2014-01-09T18:56:51.425Z What made you decide to use random mutagenesis screens — chance, basically — in your research? Q&A: Chance encounters : Nature : Nature Publishing Group 2015-10-20T04:00:00Z The host cell receptor binding site was identified by electron microscopy and mutagenesis. [Report] Hepatitis C Virus E2 Envelope Glycoprotein Core Structure 2013-12-04T22:56:38.581Z The risks associated with mutagenesis, the academy also says, are small relative to the incidence of food-borne illnesses such as salmonella. The Scariest Veggies of Them All 2013-11-22T00:24:17Z Indeed, mutagenesis experiments of the neurotensin receptor provide support for this possibility. Molecular signatures of G-protein-coupled receptors 2013-02-13T18:21:29.900Z Still today it is difficult not to be amazed by genetic variation and mutagenesis. Authenticating Cells Out of Curiosity, Not Fear 2012-11-26T13:45:00.197Z To address the concern that the virus could acquire this ability under natural conditions, we genetically modified A/H5N1 virus by site-directed mutagenesis and subsequent serial passage in ferrets. [Special Issue Report] Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets 2012-06-21T18:26:51.147Z These different mutational signatures suggest a complex mechanism of ultraviolet mutagenesis across the clinical spectrum of melanoma, probably reflecting distinct histories of environmental exposures and cutaneous biology. Melanoma genome sequencing reveals frequent PREX2 mutations 2012-05-23T17:22:14.467Z Reports from the National Academy of Sciences, representing the consensus of experts in the field, say the risk of creating unintended health effects is greater from mutagenesis than any other technique, including genetic modification. The Scariest Veggies of Them All 2013-11-22T00:24:17Z They randomly mutated genes in mice, with a technique known as insertional mutagenesis. Leukaemia genes' role discovered 2011-03-27T18:04:28Z Lethal mutagenesis appealed to many scientists at first, because it seemed to be a radically new way to fight viruses. 2010-01-05T05:56:00Z Lethal mutagenesis would be able to hit viruses even harder, Dr. Wilke argues, if it is part of a one-two punch. 2010-01-05T05:56:00Z The analysis reveals global genomic evidence for the role of ultraviolet mutagenesis in melanoma, and identifies several recurrently mutated and rearranged genes not previously implicated in this malignancy. Melanoma genome sequencing reveals frequent PREX2 mutations 2012-05-23T17:22:14.467Z Other scientists are confident they will be able to find solutions to the other problems with lethal mutagenesis. 2010-01-05T05:56:00Z Reporting their results, Dr. Loeb’s group dubbed this kind of attack “lethal mutagenesis.” 2010-01-05T05:56:00Z Another problem with lethal mutagenesis is that viruses may be able to evolve resistance to it. 2010-01-05T05:56:00Z Despite these challenges, a number of researchers see reason for optimism about lethal mutagenesis. 2010-01-05T05:56:00Z The viruses vanished much faster than they did when the scientists used lethal mutagenesis alone. 2010-01-05T05:56:00Z And there was also something inherently risky about the very idea of lethal mutagenesis. 2010-01-05T05:56:00Z A new paper to be published in the journal Genetics shows just how mysterious lethal mutagenesis remains. 2010-01-05T05:56:00Z Researchers at the University of Texas tried to use lethal mutagenesis to kill off a virus called T7, which infects only E. coli. 2010-01-05T05:56:00Z |
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