| 单词 | microtubule |
| 例句 | For decades, researchers have believed that a class of drugs called microtubule poisons treat cancerous tumors by halting mitosis, or the division of cells. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z The microtubules that form the basis of the mitotic spindle extend between the centrosomes, pushing them farther apart as the microtubule fibers lengthen. Concepts of Biology 2013-04-25T00:00:00Z Microtubules that will form the mitotic spindle extend between the centrosomes, pushing them farther apart as the microtubule fibers lengthen. Biology for AP Courses 2022-06-09T00:00:00Z Two short, identical microtubule structures called centrioles are found near the nucleus of cells. Anatomy and Physiology 2013-06-19T00:00:00Z They suspected the drug might prevent viral replication, which depends on the microtubule network to bring together the pieces of new viruses. Cancer Drug Greatly Reduces Deaths in Hospitalized Covid Patients 2022-07-06T04:00:00Z Now, a team of UW-Madison scientists has found that in patients, microtubule poisons don't actually stop cancer cells from dividing. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z Each chromatid, now called a chromosome, is pulled rapidly toward the centrosome to which its microtubule was attached. Concepts of Biology 2013-04-25T00:00:00Z Each chromatid, now called a chromosome, is pulled rapidly toward the centrosome to which its microtubule is attached. Biology for AP Courses 2022-06-09T00:00:00Z The thickest of the three is the microtubule, a structural filament composed of subunits of a protein called tubulin. Anatomy and Physiology 2013-06-19T00:00:00Z The culprit that destroyed so much of her brain is a gene called microtubule associated protein tau, or MAPT. Atypical forms of dementia are being diagnosed more often in people in their 50s and 60s 2020-12-04T05:00:00Z The assumption that microtubule poisons stop cancer cells from dividing is based on lab studies demonstrating just that. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z The researchers also developed an imaging technique to isolate—and actually see—a thin slice of microtubule growth amid the visual clutter of background molecules. Ballistic Maggots, Synthetic Winks and Why You're Not Goop: This Week's Best Science GIFs 2019-08-09T04:00:00Z There is equal chance of a microtubule fiber to encounter a maternally or a paternally inherited chromosome. Biology for AP Courses 2022-06-09T00:00:00Z A major occurrence during prophase concerns a very important structure that contains the origin site for microtubule growth. Anatomy and Physiology 2013-06-19T00:00:00Z The part of the nucleus that emerges in areas with low microtubule density is known as the region that contains ‘non-core’ nuclear-envelope components. A core problem in nuclear assembly 2018-09-18T04:00:00Z Weaver and her colleagues wanted to know if other microtubule poisons work the same way as paclitaxel -- not by stopping mitosis but by messing it up. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z The stability and functionality of microtubule assemblies depends partially on the dynamic binding of tau93, 94. The road to restoring neural circuits for the treatment of Alzheimer's disease : Nature : Nature Research 2016-11-08T05:00:00Z There is equal chance of microtubule fiber to encounter maternally or paternally inherited chromosome. Biology for AP Courses 2022-06-09T00:00:00Z He wanted to test the idea, suggested by earlier theories and experiments, that short-range microtubule–kinesin interactions by themselves were sufficient to yield spindle-like structures. The physics of life 2016-01-04T05:00:00Z This tree contains several sorts of combretastatin, and these are remarkably good at disrupting microtubule activity—which, presumably, helps protect the plant from the attentions of pests and parasites. Colourful chemotherapy 2015-07-09T04:00:00Z While microtubule poisons are no panacea, they are effective for many patients, and researchers have long sought to develop other therapies that mimic what they believe the drugs do. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z We used spinning-disk confocal microscopy to image the reorganization of cortical microtubule arrays in real time and visualize functional proteins tagged with fluorescent proteins. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z A spindle fiber that has attached to a kinetochore is called a kinetochore microtubule. Biology for AP Courses 2022-06-09T00:00:00Z At talks, she has shown videos of spherical microtubule–kinesin systems and asked audience members whether they think they are seeing a real cell. The physics of life 2016-01-04T05:00:00Z The microtubule cytoskeleton, the network of cable-like tubulin polymers found throughout the cytoplasm in all eukaryotic cells, is central to cell division and differentiation throughout biology. [Perspective] Shining Light at Microtubule Crossroads 2013-12-05T18:56:15.276Z These findings reveal the likely reason why microtubule poisons are effective for many patients. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z In this Research Article, we present evidence that one outcome of microtubule interaction, katanin-mediated severing at crossover sites, is regulated by light perception and acts to reorient the array. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z Inhibitors of microtubule assembly, vinblastine for example, are used for cancer chemotherapy. Biology for AP Courses 2022-06-09T00:00:00Z He first used sophisticated microscopes to examine extracts from frog egg cells, quantifying microtubule density, orientation and stresses during spindle formation. The physics of life 2016-01-04T05:00:00Z Here, microtubule organization patterns the deposition of cellulose, the prime constituent of cell walls, thus controlling the ability of plants to grow in the direction of light, or phototropism. [Perspective] Shining Light at Microtubule Crossroads 2013-12-05T18:56:15.276Z This may occur through inadequate detection and correction, or through increased formation, of incorrect attachments as a result of altered microtubule dynamics or transiently abnormal spindle geometry. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z The microtubule “plus” end created by severing were observed to grow preferentially, effectively building a new population of microtubules orthogonal to the initial array. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z The inhibitors bind the microtubule to the nuclear membrane, stopping cell division. Biology for AP Courses 2022-06-09T00:00:00Z And third, it involves interactions between fixed, or deterministic, factors — such as the forces exerted by the motor proteins — and random, or stochastic, factors, such as the probability of a motor protein meeting a microtubule. Systems ecology: Biology on the high seas 2013-09-04T17:20:24.237Z In a series of videos, such as the ones above and below, Dogic and his team recorded the cyclic stages through which microtubule bundles grow, bend, buckle, break and grow again. Lab-Made Droplets Move Themselves Continuously without External Force 2012-11-07T22:45:00.203Z In another feat of molecular acrobatics and precision, as the microtubule draws the captured chromosome towards the pole, it is actually shortening by losing tubulin subunits. Getting a Tighter Grip on Cell Division 2010-11-30T16:14:00Z In plants, environmental and hormonal signals that modulate cell growth cause reorganization of cortical microtubule arrays. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z How does an inhibitor of microtubule assembly affect cancerous cells? Biology for AP Courses 2022-06-09T00:00:00Z The traffic signs on this microtubule network are chemical additions such as acetylation marks. Study Identifies Critical 'Traffic Engineer' of the Nervous System 2010-09-09T14:26:00Z Each molecule of ATP propels a kinesin molecule 8 nanometers forward along the microtubule track. Lab-Made Droplets Move Themselves Continuously without External Force 2012-11-07T22:45:00.203Z There is a chance of microtubule fiber to encounter maternally inherited chromosome. Biology for AP Courses 2022-06-09T00:00:00Z Our observations show how severing is used constructively to build a new microtubule array. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z There is equal chance of a microtubule fiber to encounter a maternally or a paternally inherited chromosome. Biology for AP Courses 2022-06-09T00:00:00Z Because there is an equal chance that a microtubule fiber will encounter a maternally or paternally inherited chromosome, the arrangement of the tetrads at the metaphase plate is random. Biology for AP Courses 2022-06-09T00:00:00Z Cortical microtubule arrays in higher plants are being recognized as systems with self-organizing properties arising from rules governing the outcomes of microtubule interactions. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z The organization of cortical microtubule arrays in higher plant cells is essential for organizing cell and tissue morphogenesis, but it is not clear how specific architectures are acquired and reconfigured in response to environmental cues. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z |
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