| 单词 | levodopa |
| 例句 | Two journals have retracted papers related to Rutherford’s levodopa research, citing methodological problems. News at a glance: A win for young climate activists, a research suspension, and China’s mpox surge 2023-08-16T04:00:00Z Carbidopa/levodopa, a common first-line medication for the treatment of Parkinson’s disease motor symptoms, if taken with high protein meals, is not well absorbed, and may become less effective. Certain foods and beverages can interact with drugs 2021-12-03T05:00:00Z Martin herself recently created a tomato that produces levodopa, the primary drug for treating Parkinson’s disease, in hopes of making the drug both more affordable and more tolerable. Learning to Love G.M.O.s 2021-07-20T04:00:00Z As a result, treatment typically includes the use of levodopa—a medication that is converted into dopamine in the brain and relieves PD symptoms. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z Simply start taking levodopa, the most common medication for treating Parkinson’s disease. The true secret of happiness? Accepting that there isn’t one 2018-05-03T04:00:00Z He highlighted that the most widely used Parkinson’s drug today, levodopa, was first used in the clinic in 1967. Scientist behind Dolly the cloned sheep, a key to Parkinson’s research, has disease himself 2018-04-12T04:00:00Z “This is because levodopa competes with certain amino acids — the building blocks of proteins — for transport across the gut wall or into the brain,” Hess says. Certain foods and beverages can interact with drugs 2021-12-03T05:00:00Z Treatments, which include Botox injections and levodopa, a drug used to treat Parkinson’s disease, have been found to ease the problem. One day, a serious athlete couldn’t walk straight. Doctors were stumped. 2018-02-16T05:00:00Z For the first few years after diagnosis, many individuals’ symptoms are well controlled by levodopa. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z The most widely prescribed therapy used today — levodopa, which temporarily addresses some Parkinson's-related loss of dopamine, a movement-regulating brain chemical — wasn't discovered until the late 1960s. LIFE Shared This Remarkable Parkinson's Disease Story in 1959. A Lot Has Changed Since Then 2017-06-01T04:00:00Z The drug was tested in two six-month studies including a total of about 1,200 patients taking a standard treatment, levodopa. FDA OKs new drug as add-on treatment for Parkinson’s 2017-03-21T04:00:00Z Dopamine replacement therapies, such as the dopamine precursor levodopa, typically lead to the relief of symptoms but lose their potency as the disease progresses. Defects in trafficking bridge Parkinson's disease pathology and genetics : Nature : Nature Research 2016-11-08T05:00:00Z She began taking levodopa, which has helped normalize her walk. One day, a serious athlete couldn’t walk straight. Doctors were stumped. 2018-02-16T05:00:00Z As Parkinson’s disease progresses, a patient’s sensitivity to peak concentrations of levodopa increases. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z Most Parkinson's therapies, including deep brain stimulation and a precursor to the neurotransmitter dopamine called levodopa, ease tremors and rigidity. Diagnosis: Warning signs : Nature : Nature Research 2016-10-25T04:00:00Z According to the FDA, adding Xadago to levodopa decreased symptoms such as involuntary muscle movement. FDA OKs new drug as add-on treatment for Parkinson’s 2017-03-21T04:00:00Z Other dopamine-based therapies have since been developed, but levodopa is the gold standard for relieving the motor symptoms of Parkinson's. Two hundred steps : Nature : Nature Research 2016-10-25T04:00:00Z Some patients get small benefits from carbidopa/levodopa, a combination of drugs prescribed for patients with Parkinson’s disease, but most don’t. After a Fall, Then Another, a Devastating Diagnosis 2016-10-20T04:00:00Z Physicians may prescribe more frequent doses of levodopa or a different formulation. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z The inhaled drug was rapidly absorbed and was detectable in the bloodstream within five minutes, compared with 20 minutes after taking levodopa orally, the researchers found. Inhaled Version of Parkinson's Drug May Help Keep Symptoms at Bay 2016-10-12T04:00:00Z The mutation suggested that she might respond to a drug called levodopa, which supplies the brain with dopamine and helps some patients with Parkinson's disease. Diagnosis: A clear answer : Nature : Nature Research 2016-09-06T04:00:00Z Deep brain stimulation becomes popular as a treatment for patients who do not respond to levodopa. Two hundred steps : Nature : Nature Research 2016-10-25T04:00:00Z Drugs like levodopa can help with many of the symptoms of Parkinson's, but with prolonged use they can cause unwanted side effects, including uncontrolled jerking movements. Muhammad Ali: Boxer's battle with Parkinson’s - BBC News 2016-06-05T04:00:00Z The periods that occur when levodopa concentration drops, and a patient’s motor function subsequently declines, are known as OFF episodes. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z In particular, researchers zeroed in on patients who were administered the drug levodopa, also called L-dopa, which is used to treat Parkinson's and other movement disorders. Researchers Seek Path to Prevent Macular Degeneration 2015-12-10T05:00:00Z When mice and monkeys with Parkinson-like diseases were given a new compound that boosted the function of the receptor, there was a sharp drop in uncontrolled movement caused by levodopa, Surmeier's team said. New Clues to Easing Side Effects From Parkinson's Drug 2015-11-18T05:00:00Z But among those who took levodopa, it occurred much later, at around age 79. Parkinson's Drug Shows Promise Against Macular Degeneration 2015-11-12T05:00:00Z In the study, published in the journal Current Biology, 175 participants took part, with 89 assigned to receive the anti-depressant citalopram or a placebo and 86 given either levodopa or a placebo. Parkinson’s and depression drugs can alter moral judgment, study shows 2015-07-02T04:00:00Z Moreover, these episodes become more prevalent over time—about 40 to 50 percent of PD patients experience OFF episodes within two years of starting levodopa therapy. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z The patients in his study didn't get as much relief from the two placebos as they did from their regular medication, levodopa -- a standard Parkinson's drug. Study Underscores Power of Placebo Effect 2015-01-28T05:00:00Z When patients received the "$1,500" drug first, their motor function improved two-fold compared to cheap placebo, and 28 percent over baseline, but less than with the Parkinson's drug levodopa. 'Expensive' placebo beats 'cheap' one in Parkinson's disease: study 2015-01-28T05:00:00Z However, the study doesn't actually prove that levodopa causes a lower incidence of age-related macular degeneration. Parkinson's Drug Shows Promise Against Macular Degeneration 2015-11-12T05:00:00Z People given levodopa, however, were not willing to pay any more to prevent shocks to others than to prevent shocks to themselves. Parkinson’s and depression drugs can alter moral judgment, study shows 2015-07-02T04:00:00Z And just like maintenance levodopa, therapy should be tailored for each patient depending on their needs. A New Way to Help Manage Parkinson's 2019-01-18T05:00:00Z What's more, patients' brain activity on the pricey placebo was similar to what was seen with levodopa. Study Underscores Power of Placebo Effect 2015-01-28T05:00:00Z In fact, the effect of the expensive placebo was not significantly different from that of levodopa, the most effective medication for Parkinson’s disease. Expensive Drugs Work Better Than Cheap Ones 2015-01-28T05:00:00Z Bernstein also cautioned that this study doesn't confirm that levodopa will help people with age-related macular degeneration or those at risk for developing it. Parkinson's Drug Shows Promise Against Macular Degeneration 2015-11-12T05:00:00Z Civitas’ main asset is an inhaled form of levodopa, the main treatment for Parkinson’s disease. For Second Act, Acorda Drops $525 Million On Inhaled Parkinson's Drug 2014-09-24T04:00:00Z Research published June 10 in The Lancet finds that the dopamine drug levodopa still outperforms newer medications for the long-term care of people newly diagnosed with Parkinson's. Levodopa May Beat Newer Meds for Long-Term Parkinson's Care: Study 2014-06-11T04:00:00Z But the magnitude of the expensive placebo's benefit was about halfway between that of the cheap placebo and levodopa, according to the researchers. Study Underscores Power of Placebo Effect 2015-01-28T05:00:00Z To ease symptoms of Parkinson's, some patients take levodopa and other drugs that increase dopamine levels. How the Brain Gets Addicted to Gambling 2013-11-05T13:15:03.103Z In Parkinson's patients, levodopa causes side effects such as nausea and low blood pressure, but McKay said side effects in people without Parkinson's are unknown. Parkinson's Drug Shows Promise Against Macular Degeneration 2015-11-12T05:00:00Z The tremors, rigidity and difficulty moving are often treated with anti-Parkinson's medications such as levodopa at first. Can Early Deep-Brain Stimulation Surgery Help More Parkinson's Patients? 2013-02-13T22:45:00.257Z How will this work lead to new treatments for the Parkinson's patient whose levodopa no longer works? [Essay] Eppendorf Finalist: Striatal Interneurons: Causes of or Cures for Movement Disorders? 2012-10-04T17:56:00.157Z Azilect received FDA approval in 2006 for use as a single drug therapy in early Parkinson's and, in more advanced patients, in addition to levodopa, a standard treatment for the disease that alleviates the symptoms. U.S. advisers doubt Teva Parkinson's drug claim 2011-10-17T22:24:05Z It mimics some of cerebral palsy's symptoms but is treatable with the Parkinson's drug levodopa. Personal genome map solves teen's illness 2011-06-15T23:25:04Z In the body, levodopa turns into dopamine, a naturally occurring chemical that appears linked to normal function of the retina, McKay said. Parkinson's Drug Shows Promise Against Macular Degeneration 2015-11-12T05:00:00Z A variety of standard medicines, including levodopa, moderate symptoms for many patients, but symptoms tend to worsen over time. Lilly, Medtronic team up on Parkinson's strategy 2011-04-26T18:48:28Z Weintraub said there was also an association with the impulsive behaviors in patients taking levodopa, but it was much weaker. Parkinson's drugs linked with compulsive behaviors 2010-05-10T21:02:00Z Since the 1970s, a number of case reports have suggested that levodopa therapy for Parkinson's disease increases the risk of skin cancer. Melanoma risk higher in Parkinson's patients 2010-03-08T21:44:00Z In the current study, nearly 85 percent of the patients had taken levodopa, but the researchers found no evidence that this drug was associated with melanoma risk. Melanoma risk higher in Parkinson's patients 2010-03-08T21:44:00Z |
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