| 单词 | interleukin |
| 例句 | Research at Duke University reveals that rat pups who received lots of loving contact from their mothers had higher brain levels of interleukin-10, a molecule that suppresses a craving for morphine. 10 reasons we love love 2014-03-15T22:00:00Z The drug, which in the UK is approved to treat rheumatoid arthritis, blocked the protein interleukin-6, which can cause inflammation. Breakthrough for 'neglected' rheumatic condition 2023-10-25T04:00:00Z One of these proteins, interleukin 6, has been linked to conditions such as rheumatoid arthritis, Type 2 diabetes and chronic stress. 7 tips for eating and living well in 2023 2023-01-11T05:00:00Z A central player in the pathway to nausea and retching was an immune system molecule called interleukin 33, or IL33. How Brains Send a Signal That It’s Time to Vomit 2022-11-01T04:00:00Z Doctors have already trialled an interleukin-1-beta drug in cardiovascular disease and found, by complete accident, they cut the risk of lung cancer. Air pollution cancer breakthrough will rewrite the rules 2022-09-10T04:00:00Z The drug cyclosporine is used to suppress immune rejection of organ transplants by inhibiting production of interleukin, a cytokine messenger that increases expression in T cells. Biology for AP Courses 2022-06-09T00:00:00Z There are two major subtypes of cytokines known as colony-stimulating factors and interleukins. Anatomy and Physiology 2013-06-19T00:00:00Z One clue emerged earlier this year when Genentech scientists showed how nanoparticles activate a particular inflammatory pathway, the interleukin-1 axis, which is critical to generating protective immune responses but can also spur side effects. Better fat bubbles could power a new generation of mRNA vaccines 2022-05-12T04:00:00Z After the long interval, the T cells of study participants produced greater quantities of interleukin-2, a chemical signal that helps long-term immune memory. Parents Grapple With How Long to Wait for Their Children’s Second Shots 2021-12-20T05:00:00Z The children had higher levels of signalling proteins such as interferons and interleukins, and higher expression of the genes that code for such proteins. Why Kids Beat Back COVID Better Than Adults 2021-09-15T04:00:00Z Design an experiment to test the use of conditioning using the administration of cyclosporine as the unconditioned stimulus and sugar water as the conditioned stimulus by measuring the blood concentration of interleukin. Biology for AP Courses 2022-06-09T00:00:00Z Researchers now suspect that interleukins may play other roles in body functioning, including differentiation and maturation of cells, producing immunity and inflammation. Anatomy and Physiology 2013-06-19T00:00:00Z Then they measured levels of specific cytokines—immunoregulatory proteins such as interleukin and interferon that are secreted by immune cells—and looked for correlations between those levels and a suite of immune gene variants. How ancient farmers throttled their immune systems to survive 2021-09-06T04:00:00Z Among the compounds that showed declines was interleukin-6, an inflammatory protein that tends to be elevated in diseases such as Type 2 diabetes and rheumatoid arthritis. How fermented foods may alter your microbiome and improve your health 2021-08-15T04:00:00Z By contrast, the children in the study had higher levels of the signalling proteins interferon-γ and interleukin-17, which alert the immune system to the arrival of a pathogen. Why Kids Beat Back COVID Better Than Adults 2021-09-15T04:00:00Z Assume that interleukin is flushed from the blood in a single day. Biology for AP Courses 2022-06-09T00:00:00Z Production of all leukocytes begins in the bone marrow under the influence of CSFs and interleukins. Anatomy and Physiology 2013-06-19T00:00:00Z In February, Recovery investigators announced that tocilizumab, a monoclonal antibody that blocks the receptor for interleukin-6, reduced mortality a bit further. A giant trial of COVID-19 treatments is restarting. Here are the drugs it’s betting on 2021-08-05T04:00:00Z And the participants with the lowest levels of interleukin-6, were the participants who reported feeling awe most often. It’s OK to Feel Joy Right Now 2021-03-19T04:00:00Z Last month, another arm of the Recovery trial found mortality reductions with tocilizumab, a newer, more expensive anti-inflammatory drug approved to treat rheumatoid arthritis that blocks inflammatory signaling by the molecule interleukin-6. How do you treat coronavirus? Here are physicians’ best strategies 2021-03-16T04:00:00Z Produced early in the course of infection, interleukin 17A may help children thwart the virus’s attempts to evade the innate response and to ward off the later adaptive response. How Do Children Fight Off the Coronavirus? 2020-09-25T04:00:00Z To date, more than a dozen interleukins have been identified, with others likely to follow. Anatomy and Physiology 2013-06-19T00:00:00Z The authors mapped the transcription factors activated by the interleukins. Research round-up: Cystic fibrosis 2020-07-28T04:00:00Z Together with the activated endothelial cells, the immune cells release a host of signaling molecules, including interleukins, which raise local blood pressure and weaken cell junctions. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z Doctors treated him with interleukin inhibitors to slow inflammation, along with the antimalarial drug hydroxychloroquine and the antibiotic azithromycin. ‘Will You Help Save My Brother?’: The Scramble to Find Covid-19 Plasma Donors 2020-04-29T04:00:00Z The Spanish-born professor in the University of Colorado’s Department of Immunology and Microbiology was doing postdoctoral work at Yale when she stumbled upon an article about interleukin-6, or IL-6. COVID diaries Colorado: A day in the coronavirus pandemic 2020-04-26T04:00:00Z They are trying to find out, for instance, whether using antibodies to block interleukin 6 or complement component 5, two signaling molecules that play a role in the human immune defense, can help patients. These drugs don’t target the coronavirus—they target us 2020-04-02T04:00:00Z Finally, in post-mortem lung tissue, the interleukin, mucin and transcription factor genes were found to be highly active in people with cystic fibrosis and almost silent in control samples. Research round-up: Cystic fibrosis 2020-07-28T04:00:00Z Although there's value in understanding the link between these molecules and concussions, the problem remains that biomarkers like interleukins are not specific to concussions. Scientists are trying to diagnose concussions through a simple blood test 2020-03-21T04:00:00Z But the good news for him was that there is a drug on the market — anakinra, used to treat rheumatoid arthritis — that blocks interleukin 1. When the Illness Is a Mystery, Patients Turn to These Detectives 2019-01-07T05:00:00Z The researchers injected some of the mice with the cytokines interleukin-1 beta and tumor necrosis factor. Could Future Nerve Implants Detect and Monitor Illness? 2018-05-10T04:00:00Z His preliminary studies found that cells lining the uterus of placental mammals suppress the production of interleukin-17. Armadillo, Hedgehog and Rabbit Genes Reveal How Pregnancy Evolved 2018-01-10T05:00:00Z Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction. IL-11 is a crucial determinant of cardiovascular fibrosis 2017-11-12T05:00:00Z Over the course of a decade, Libby and Ridker found themselves focusing on a molecule involved in inflammation called interleukin-1 beta. Can Heart Disease Shed Light on Cancer? 2017-09-27T04:00:00Z Levels of a protein called interleukin 10, which helps to prevent inflammatory disease and ensure successful pregnancy, went up, as did an important hormone called oxytocin. Microbes, a Love Story 2017-02-10T05:00:00Z The treatment with interleukin 33 seemed to improve memory and help prevent and disperse brain deposits similar to those that occur in people with Alzheimer's, BBC News reported. Health Highlights: April 19, 2016 2016-04-19T04:00:00Z They also found higher levels of interleukin-6 in the blood of the runners. How Exercise May Lower Cancer Risk 1456-10-14T05:00:00Z Targeted treatments for kidney cancer are less toxic and more effective than immunotherapy such as interferon and interleukin drugs, Weiss says. Finding Out You Have Kidney Cancer 2015-12-04T05:00:00Z By the mid-2000s, they heard of a new drug — an interleukin-1-beta inhibitor — that was used to treat exceedingly rare inflammatory diseases. Can Heart Disease Shed Light on Cancer? 2017-09-27T04:00:00Z He found that a single inflammatory molecule, called interleukin-6, was the most powerful predictor of who would eventually become disabled. Medicine’s Burning Question 2015-11-30T05:00:00Z Dr. Paul, with Maureen Howard, also discovered the molecule interleukin-4, an advance that led to the development of therapies for allergic and inflammatory disorders. Dr. William E. Paul, Who Helped AIDS Research Save Millions of Lives, Dies at 79 2015-09-22T04:00:00Z The fungus in two vials of albumin -- used to administer the drug interleukin -- was discovered in April, The New York Times reported. Health Highlights: June 5, 2015 2015-06-05T04:00:00Z The vials of albumin, a protein in blood, were being used to administer the drug interleukin, which may be used to battle some forms of cancer. NIH suspends operations of drug unit after fungal contamination in vials 2015-06-04T04:00:00Z But if the benefit holds up in future trials, interleukin-1-beta inhibition could eventually rank among the most effective prevention strategies in the recent history of cancer. Can Heart Disease Shed Light on Cancer? 2017-09-27T04:00:00Z The day I visited, they were assessing molecules associated with colitis, especially one called interleukin-10, or IL-10, which is known to decrease inflammation. Medicine’s Burning Question 2015-11-30T05:00:00Z In April, two vials of albumin, a substance used to administer the drug interleukin, were found to contain fungus, the N.I.H. said in a statement. N.I.H. Finds Contamination at Pharmacy 2015-06-04T04:00:00Z The study authors noted that previous research has shown that obesity causes inflammation from chemicals called interleukins that are released from excess fat cells. Weight-Loss Surgery Might Reduce Serious Asthma Flare-Ups 2015-03-27T04:00:00Z The students then supplied saliva samples, which were analyzed for interleukin-6, a molecule known to promote inflammation throughout the body. An Upbeat Emotion That's Surprisingly Good for You 2015-03-26T04:00:00Z Similarly, sleeplessness reduced levels of interleukin-6, a protein involved in the body's response to infection, but remained at normal levels when the men were allowed to nap. Rough night? Show this post on the value of napping to your supervisor. 2015-02-13T05:00:00Z After napping, the men's norepinephrine and interleukin-6 levels were normal. Naps May Improve Your Health 2015-02-10T05:00:00Z Then the researchers tested the effects of injecting lab mice with interleukin-33 -- an immune system protein that acts like a "chemical messenger" among cells. Immune System May Play Role in Obesity 2014-12-22T05:00:00Z In April, at least five CAR-T-cell trials were halted after a series of patient deaths linked to unusually high levels of a protein called interleukin-6, which promotes inflammation, as well as other inflammatory molecules. Immune cells boost cancer survival from months to years 2014-12-09T05:00:00Z The next morning, she began the second phase of the treatment, which involves doses of interleukin-2, a hormone that encourages the TILs to grow, every eight hours. Cancer was killing her. She tried immunotherapy. However, overweight or obese individuals exhibited an interleukin-6 response on the second day nearly double that of their response the day before. Stress Might Be Even More Unhealthy for the Obese 2014-09-26T04:00:00Z The year that the young man in Boston died, my colleagues and I identified a variant associated with asthma in the gene for interleukin 4, a cell-signalling protein that coordinates immune and inflammatory responses. Medical research: Missing patients 2014-09-15T04:00:00Z “One way it does this is by producing extra interleukins—chemicals that help regulate the immune system—providing at least a temporary defensive boost.” 5 Weird Ways Stress Can Actually Be Good for You 2014-08-22T04:00:00Z It acts against interleukin-17 receptor A, a substance found in higher levels in people with psoriatic arthritis, according to the study. Drug Shows Promise Against Arthritis Common in People with Psoriasis 2014-06-11T04:00:00Z The participants who had greater brain activity when trying to control their negative emotions also had higher levels of interleukin-6 and more signs of atherosclerosis. Researchers Shed Light on Link Between Stress, Heart Trouble 2014-05-13T04:00:00Z Normal weight people did not exhibit this escalation in interleukin-6 levels when exposed to repeated stress. Stress Might Be Even More Unhealthy for the Obese 2014-09-26T04:00:00Z She was also given a drug, interleukin-2, which helps activate T cells. Promising test gives cancer a beating using patient’s cells 2014-05-09T02:19:29Z Trained recruits also produced lower amounts of several proteins associated with inflammation, and higher levels of an inflammation-fighting protein called interleukin-10. Inflammation Reduced with Behavioral Training 2014-05-06T13:35:00Z As they grew rotund and accumulated more fat cells, the researchers found, their blood showed increasingly hefty doses of a substance called interleukin 1 that is created by fat cells and known to cause inflammation. Well: How Fat May Hurt the Brain, and How Exercise May Help 2014-03-05T05:01:35Z In this study, published in the Journal of Allergy and Clinical Immunology, vitamin D was able to lower levels of interleukin-17 when it was added to blood samples taken from 28 patients. Sunshine vitamin may 'treat asthma' 2013-05-20T00:39:04Z Researchers found that overweight people repeatedly placed in a stressful situation exhibited increasing amounts of interleukin-6, a protein that promotes inflammation in the body, in their saliva. Stress Might Be Even More Unhealthy for the Obese 2014-09-26T04:00:00Z When microbes trigger lymphocytes in the body, the lymphocytes secrete cytokine signal molecules, such as interleukin 1 or 6. Wired and Wireless Components of the Brain 2013-03-14T17:15:00.450Z Some forms of autoimmunity have been linked to overproduction of TH17 cells, a type of helper T cell that produces an inflammatory protein called interleukin-17. Salt Linked to Autoimmune Diseases 2013-03-06T22:45:00.627Z It reduces the number of eosinophils by inhibiting an immune system signaling chemical called interleukin-5. GSK drug halves attacks in hard-to-treat asthma 2012-08-16T23:02:25Z They are looking at patients who do not respond to steroids as they produce seven times more interleukin-17 than other patients. Sunshine vitamin may 'treat asthma' 2013-05-20T00:39:04Z There is undoubtedly a role of the innate immune system and inflammation in beta-cell destruction; clinical trials testing this hypothesis, including blocking the proinflammatory protein interleukin-1, are underway. Perspective: Rethink the immune connection 2012-05-22T15:21:10.863Z The massaged leg showed slower production of interleukin-6 and tumor necrosis factor alpha, both linked to inflammation, according to the report. Massage After Exercise Tamps Down Inflammation That Causes Aches 2012-02-01T19:23:40Z One such cytokine, interleukin-17, causes inflammation by increasing the activity of osteoblasts and myeloma cells and thus encouraging bone degradation and tumour growth. Orthopaedics: Structural support 2011-12-14T18:21:16.733Z The drug, which is already sold for treating cryopyrin-associated periodic syndromes, a rare inflammatory disorder, works by blocking a protein called interleukin-1 beta linked to inflammation. Novartis drug helps in severe childhood arthritis 2011-11-07T07:07:34Z Her group investigated the impact of the vitamin on a chemical in the body, interleukin-17. Sunshine vitamin may 'treat asthma' 2013-05-20T00:39:04Z Injection of a general anti-inflammatory drug or a specific interleukin-1 inhibitor to donor mice after MI prevented this impairment. [Research Articles] Donor Myocardial Infarction Impairs the Therapeutic Potential of Bone Marrow Cells by an Interleukin-1-Mediated Inflammatory Response 2011-09-14T18:55:08.747Z The newer drugs targets two different inflammatory proteins -- interleukin 12 and interleukin 23. No major heart risk seen in new psoriasis drugs 2011-08-23T20:30:09Z The growing roll call of interleukins is now up to IL-38, he notes. Body's Immune Protein Fights Breast Cancer 2011-04-14T14:43:00Z Only two other drugs are currently used to treat advanced melanoma: dacarbazine, a chemotherapy agent, and interleukin-2, which is so toxic it's rarely used. Health Buzz: FDA Approves New Melanoma Drug 2011-03-28T16:38:00Z All these interleukin 6 functions are potential therapeutic targets. Japan Prizes Honor Immune System and Computer Science Research 2011-01-25T16:11:15Z The proportion of individuals with measurable levels of the pro-inflammatory cytokine interleukin 1 is higher in the patient group. Exhaustion Syndrome Leaves Measurable Changes in the Brain 2010-11-22T16:33:00Z A gene called interleukin-18 is activated from the mother’s version in two important regions of the brain. Tug of War Pits Genes of Parents in the Fetus 2010-09-14T04:50:00Z For the most part, interleukins are specific to their receptors, he says, “but there are individual examples of this cross talk.” Body's Immune Protein Fights Breast Cancer 2011-04-14T14:43:00Z It also secretes tumor necrosis factor, interleukin 6, and C-reactive protein which lead to high blood pressure, insulin resistance, high cholesterol and inflammation that damages our brains & blood vessels. Waist Size Linked With Longevity 2010-08-09T21:44:00Z They determined interleukin 6's role in rheumatoid arthritis, and to treat the disorder they helped develop a drug that blocks the molecule's activity. Japan Prizes Honor Immune System and Computer Science Research 2011-01-25T16:11:15Z In the fetus, the strongest gene influence was the interleukin 6 receptor, which is involved in the body's response to inflammation. 2010-02-04T05:04:00Z To test the role of interleukin-25, they implanted 15 mice with breast tumors and injected the tumors with either IL-25 or a saline placebo daily. Body's Immune Protein Fights Breast Cancer 2011-04-14T14:43:00Z The new study adds to the growing knowledge of interleukins, which are members of an immune-messenger club called cytokines that play a wide variety of roles in the body. Body's Immune Protein Fights Breast Cancer 2011-04-14T14:43:00Z |
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