| 单词 | antitumor |
| 例句 | The scientists showed they could precisely interrupt the flow of the differentiation process, thereby enhancing antitumor efficacy. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z Macrophages were not the only immune cells affected; while the proliferation of T cells was unchanged, their antitumor activity was suppressed due to the immunosuppressive factors produced by senescent macrophages. Cancer stem cells trigger macrophage aging 2023-11-14T05:00:00Z The monoclonal antibody bevacizumab gained regulatory approval in 2004 for patients with advanced colon cancer, and more than a dozen other angiogenesis inhibitors have since joined the antitumor arsenal. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z These enhanced approaches will likely lead to longer-lasting antitumor responses. The Next Wave of Immuno-Oncology 2019-05-20T04:00:00Z The research team was surprised and excited by the bacteria’s antitumor effects. Bacterial injections into tumors show early promise for treating cancer 2018-10-01T04:00:00Z Even more promising, when the researchers combined their modified T cells with a type of immunotherapy called immune checkpoint blockade, they further increased antitumor activity. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z Even the idea that IDO blunts the antitumor effects of checkpoint inhibitors is suspect. A promising new cancer drug has hit a major setback, raising questions about whether the field is moving too fast 2018-05-09T04:00:00Z For example, it might be possible to beef up a patient’s antitumor response with probiotics. Gut microbes give anticancer treatments a boost 2015-11-05T05:00:00Z These compounds seem to work by preventing the body from making pro-inflammatory compounds, whilst they also exert antitumor effects in colorectal cancer cells. What Actually Is In Frankincense And Myrrh? [AUDIO] 2014-12-31T05:00:00Z The biochemical mechanisms underlying their antitumor activity are unknown. [Report] The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins 2014-01-16T18:57:03.458Z One of the researchers, Dr Wayne Hancock, said: "We needed to find a way to reduce Treg function in a way that permits antitumor activity without allowing autoimmune reactions." Immune system boost 'fights cancer' 2013-08-18T17:38:00Z This antitumor effect was dependent on CD8 T cells. [Research Articles] Mucosal Imprinting of Vaccine-Induced CD8+ T Cells Is Crucial to Inhibit the Growth of Mucosal Tumors 2013-02-13T19:25:06.490Z TIC10 is an efficacious antitumor therapeutic agent that acts on tumor cells and their microenvironment to enhance the concentrations of the endogenous tumor suppressor TRAIL. [Research Articles] Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects 2013-02-06T21:55:05.167Z These findings demonstrate the favorable engraftment fitness for human T-derived clones, but further efforts to improve their antitumor efficacy are still necessary. [Research Articles] The Stoichiometric Production of IL-2 and IFN-{gamma} mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in Humans 2012-08-29T19:25:13.800Z Oncolytic viruses, which preferentially lyse cancer cells and stimulate an antitumor immune response, represent a promising approach to the treatment of cancer. [Research Articles] Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients 2012-06-13T18:55:08.080Z Despite some success, enhancing tumor antigen presentation, promoting a protective antitumor response, and overcoming the immunosuppressive tumor microenvironment pose considerable challenges that necessitate further improvements in vaccine design. [Research Articles] Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses 2012-02-08T20:55:11.063Z Future models that test antitumor immunity should also consider the effects of multiple doses of chemotherapy administered with immunosuppressive medications to accurately model the delivery of chemotherapy in patients. [Perspective] Cancer: Autophagy in Tumor Immunity 2011-12-15T18:55:36.257Z Despite their phenotypic markers of terminal differentiation, T17 cells mediated and promoted long-term antitumor immunity in in vivo adoptive transfer experiments. [Research Articles] Human TH17 Cells Are Long-Lived Effector Memory Cells 2011-10-12T19:25:05.093Z Successful adoptive T cell therapy to treat cancer requires engraftment of antitumor T lymphocytes that not only retain specificity and function in vivo but also display an intrinsic capacity to survive. [Research Articles] Establishment of Antitumor Memory in Humans Using in Vitro-Educated CD8+ T Cells 2011-04-27T18:55:17.370Z Instead of attacking, these turncoats infiltrate the cancer and "essentially wall it off from the antitumor effects of the immune system," says tumor immunologist Robert Vonderheide of the University of Pennsylvania's Abramson Cancer Center. Good News About a Very Bad Cancer 2011-03-24T19:01:00Z Nanocarriers are selectively accumulated in tumors as a result of their enhanced permeability and retention of macromolecules, thereby enhancing the antitumor activity of the nanocarrier-associated drugs. [Research Articles] Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting 2011-01-06T15:27:54.987Z Moreover, these CTLs trafficked to the tumor, mediated biological and clinical responses, and established antitumor immunologic memory. [Research Articles] Establishment of Antitumor Memory in Humans Using in Vitro-Educated CD8+ T Cells 2011-04-27T18:55:17.370Z |
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