| 单词 | factor VIII |
| 例句 | Mr Evans' father was among thousands of people to be infected by contaminated blood in the 1970s and '80s after being given a blood clotting agent called factor VIII. Infected blood inquiry: Son 'will never come to terms' with scandal 2023-02-03T05:00:00Z Only 15% of people with haemophilia have haemophilia B. Most have haemophilia A—a genetic disorder caused by a deficiency in a different blood-clotting protein called factor VIII, which is encoded by a different gene. $3.5-Million Hemophilia Gene Therapy Is World’s Most Expensive Drug 2022-12-09T05:00:00Z This disorder results in the inability to synthesize sufficient quantities of factor VIII. Hemophilia B is the second most common form, accounting for approximately 20 percent of cases. Anatomy and Physiology 2013-06-19T00:00:00Z By the mid 1970s, a new treatment for haemophilia, known as factor VIII/IX, became available for the first time. Contaminated blood inquiry: The school where dozens of pupils died 2021-06-20T04:00:00Z However, VWF sets a cap on factor VIII’s time in the body, limiting its half-life to about 15 hours. New fusion protein treatment holds promise for people with ‘royal’ clotting disorder 2020-09-09T04:00:00Z Those with the condition are either missing or low on a clotting protein called factor VIII, or FVIII. UK boy with severe, unexplained bruising diagnosed with rare blood disorder after parents accused of abuse 2019-07-26T04:00:00Z Many people with a severe form of haemophilia A develop antibodies against factor VIII, which makes replacement therapy more costly and complicated, says Almeida-Porada. Prenatal gene therapy offers the earliest possible cure 2018-12-11T05:00:00Z They cannot carry a large gene, and the gene for factor VIII, needed to treat hemophilia A, is enormous. They Thought Hemophilia Was a ‘Lifelong Thing.’ They May Be Wrong. 2018-08-13T04:00:00Z Like 2,000 other people in the UK, his body could not make clotting factor VIII. Haemophilia trial's 'mind-blowing' result 2017-12-13T05:00:00Z Each patient was given a single injection of recombinant factor VIII, followed by a washout period of at least 3 days before an injection of the fusion protein BIVV001. New fusion protein treatment holds promise for people with ‘royal’ clotting disorder 2020-09-09T04:00:00Z In the United States and other wealthy countries, most patients receive recombinant factor VIII, Walsh said. 2 New Findings Offer Hope for Those With Severe Hemophilia 2016-05-25T04:00:00Z These cells find their way back to the bone marrow, where they will eventually produce platelets that contain functioning factor VIII. Gene therapy: Genie in a vector : Nature : Nature Publishing Group 2014-11-25T05:00:00Z For factor VIII, Fc fusion extends the half-life from a maximum of about 12 hours to about 18 hours. Clotting factors: Stretching time : Nature : Nature Publishing Group 2014-11-25T05:00:00Z The virus is used like a postman to deliver the genetic instructions to the liver, which then starts producing factor VIII. Haemophilia trial's 'mind-blowing' result 2017-12-13T05:00:00Z About half of the association between stroke and AB blood type in the previous study was related to higher levels of clotting factor VIII, a blood protein that helps blood clot to stop bleeding. Study: Rare Blood Type May Slightly Raise Dementia Risk 2014-09-10T04:00:00Z That led to the development of genetically engineered "recombinant" factor VIII. 2 New Findings Offer Hope for Those With Severe Hemophilia 2016-05-25T04:00:00Z Hemophilia A is caused by a lack of clotting factor VIII, while hemophilia B is caused by a lack of clotting factor IX. New hemophilia drugs aim to simplify treatment 2014-03-07T12:06:46Z The only real difference is between factor IX, for which the techniques are offering extensions long enough to make a substantial difference in treatment, and factor VIII, for which the improvement has been more modest. Clotting factors: Stretching time : Nature : Nature Publishing Group 2014-11-25T05:00:00Z Of the 13 patients given higher doses, all are off their haemophilia medication a year on and 11 are producing near-normal levels of factor VIII. Haemophilia trial's 'mind-blowing' result 2017-12-13T05:00:00Z Too little factor VIII, and a person's blood doesn't clot properly. Study: Rare Blood Type May Slightly Raise Dementia Risk 2014-09-10T04:00:00Z An international team of researchers randomly assigned 264 young children newly diagnosed with severe hemophilia to start replacement therapy with either blood-derived or recombinant factor VIII. 2 New Findings Offer Hope for Those With Severe Hemophilia 2016-05-25T04:00:00Z The two main forms of the disease are hemophilia A, caused by a lack of clotting factor VIII, and hemophilia B, caused by a lack of clotting factor IX. Gene therapy proves effective for hemophilia B 2011-12-11T03:11:57Z Hemophilia B is much less common than hemophilia A, a deficiency of clotting factor VIII. Gene therapy proves effective for hemophilia B 2011-12-10T16:12:22Z The two main forms of the disease are hemophilia A, caused by a lack of clotting factor VIII, and the less-common hemophilia B, caused by a lack of clotting factor IX. Biogen to build blood disorder drug franchise 2011-03-04T16:42:26Z The drug is a lab-generated antibody that "mimics" the form of factor VIII, which allows it to do the protein's job. 2 New Findings Offer Hope for Those With Severe Hemophilia 2016-05-25T04:00:00Z |
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