| 单词 | endotoxin |
| 例句 | The horseshoe crab is a primitive fossil of a beast, ancient and uncitified, but he is just as vulnerable to disorganization by endotoxin as a rabbit or a man. The Lives of a Cell 1974-01-01T00:00:00Z It is when confronted by the overwhelming signal of free molecules of endotoxin, evoking memories of vibrios in great numbers, that the limulus flies into panic, launches all his defenses at once, and destroys himself. The Lives of a Cell 1974-01-01T00:00:00Z There is nothing intrinsically poisonous about endotoxin, but it must look awful, or feel awful, when sensed by cells. The Lives of a Cell 1974-01-01T00:00:00Z They display lipopolysaccharide endotoxin in their walls, and these macromolecules are read by our tissues as the very worst of bad news. The Lives of a Cell 1974-01-01T00:00:00Z Extracts of the hemocytes can be made to jell by adding extremely small amounts of endotoxin. The Lives of a Cell 1974-01-01T00:00:00Z The blood coagulates on contact with endotoxin, a biochemical component of certain bacteria, including many that cause disease. Millions of horseshoe crabs spawn on the shores of Delaware Bay each year. Here’s how to see them. 2018-04-26T04:00:00Z The doctors injected the men with an endotoxin, which usually elicits flu-like symptoms, while they practised Hof’s meditation and breathing techniques. Can the cold make you stronger? 2016-03-13T05:00:00Z This might cause inflammation of the bowels, exacerbated by various dietary ingredients and their metabolites, with further possible health problems caused by bacterial endotoxins. Animal Doctor: How pet owners, and other animals, grieve a loss 2017-05-19T04:00:00Z They have lots of fiber and protein, but also doesn't pack any saturated fat, antibiotics or endotoxins. How much protein is too much protein? 2023-10-11T04:00:00Z She noted examples from when the pharmacist and drug procurer each testified under oath in depositions that the lethal injection chemicals were tested for endotoxins. Tennessee says pair gave incorrect execution drug testimony 2023-01-25T05:00:00Z Only once was a drug tested for endotoxins— one of three required tests — during a May 2018 apparent “test run” before the protocol’s completion. 2 Tenn. officials fired after lethal injection errors noted 2023-01-19T05:00:00Z Nor was there any evidence the state ever told the pharmacy it had to test for endotoxins on all injection chemicals until the night before Smith’s planned execution, the report said. Report shines new light on execution secrecy in Tennessee 2022-12-29T05:00:00Z The records showed experts — who were not named — say testing was not performed for so-called endotoxins, which usually come from bacteria. Gov. Lee: Execution report complete, will release later 2022-12-16T05:00:00Z One problem is that bacterial cell walls often contain toxic compounds named endotoxins that need to be removed during the purification of phages, Ceyssens notes. There’s now a cleaner, better way to create viruses that kill antibiotic-resistant bacteria 2022-07-19T04:00:00Z The independent report later found drugs were not tested for endotoxins in any execution attempts since a new three-drug protocol was implemented in 2018. Tennessee says pair gave incorrect execution drug testimony 2023-01-25T05:00:00Z The filings also say that the pharmacy didn’t test every drug for endotoxins — testing that could be an indication of problems with the manufacture of the drugs. Tennessee execution pause through 2022 could last longer 2022-06-13T04:00:00Z The governor’s office later disclosed that the drugs had not been tested for endotoxins. Records: 2 people in execution knew drugs hadn’t been tested 2022-05-13T04:00:00Z He later added last week that the drugs to be used in Smith’s execution were tested for potency and sterility, but not endotoxins, as required by the state’s execution protocols. Tenn. expects changes to lethal injection protocol, staffing 2022-05-10T04:00:00Z On Monday, Lee finally elaborated in a new statement, saying the drugs to be used in Smith’s execution were tested for potency and sterility, but not endotoxins, as required by the state’s execution protocols. Tennessee governor won’t release records on execution error 2022-05-03T04:00:00Z After the pharmacist first testified the drugs are tested for endotoxins, the investigation found he later said he didn’t know endotoxin testing was required, Henry wrote. Tennessee says pair gave incorrect execution drug testimony 2023-01-25T05:00:00Z “The failure to test for endotoxins is a violation of the protocol. Governor Lee did the right thing by stopping executions because of this breach.” Tennessee Halts Executions After Failing to Test Lethal Injection Drugs 2022-05-02T04:00:00Z In them, experts say testing was not performed for so-called endotoxins, which usually come from bacteria. Records: 2 people in execution knew drugs hadn’t been tested 2022-05-13T04:00:00Z Pharmacopeia to adopt recombinant Factor C as an alternative test for endotoxins. Opinion | Saving the horsehoe crabs from decline 2021-08-11T04:00:00Z “As it is now, the entire supply chain for endotoxin testing of drugs rests upon the harvest of a vulnerable or near extinct sea creature,” Williams said. A horseshoe crab’s blood is vital in testing drugs. Critics say using it endangers the ancient creature. 2021-07-30T04:00:00Z The drug procurer, meanwhile, was receiving the test results showing endotoxin testing was not happening, she added. Tennessee says pair gave incorrect execution drug testimony 2023-01-25T05:00:00Z Billions of vaccine doses would eventually require endotoxin testing. Tests for Coronavirus Vaccine Need This Ingredient: Horseshoe Crabs 2020-06-03T04:00:00Z However, the endotoxins themselves likely wouldn’t cause a problem in an execution setting because endotoxins typically are not immediately fatal, according to Frank Romanelli, professor of pharmacy at the University of Kentucky College of Pharmacy. Records: 2 people in execution knew drugs hadn’t been tested 2022-05-13T04:00:00Z Scientists harnessed nature’s ingenuity, using crab blood to make so-called amebocyte lysate endotoxin tests which, by the 1970s, began displacing tests on rabbits that were injected with medicine then monitored for fever. Blue-blooded crabs at heart of pharma dispute on drug testing 2019-08-01T04:00:00Z In another he was injected with an E coli endotoxin that would ordinarily induce sickness, yet he showed no major symptoms. A cold-water cure? My weekend with the ‘Ice Man’ 2019-05-08T04:00:00Z “It is true, as Plaintiff points out, that the independent investigation revealed certain employees or agents of Defendants incorrectly testified that lethal injection chemicals were tested for endotoxins,” the state’s court filing says. Tennessee says pair gave incorrect execution drug testimony 2023-01-25T05:00:00Z The scientists focused on a microbial byproduct called endotoxin, which usually spurs white blood cells into action. Educate Your Immune System 2016-06-03T04:00:00Z Tennessee’s execution protocols require any compounded drugs to be independently tested for potency, sterility and endotoxins. Records: 2 people in execution knew drugs hadn’t been tested 2022-05-13T04:00:00Z Then the researchers turned to humans, exposing human lung cells to endotoxins. Here's why farm kids have fewer allergies and less asthma 2015-09-03T04:00:00Z In mice engineered to lack the gene for A20 in their lung epithelial cells, endotoxins did not protect the animals from asthma. Dirty farm air may ward off asthma in children 2015-09-03T04:00:00Z But Cani also found the junk-food diet made the animals’ gut barriers notably more permeable, allowing endotoxins to leak into the bloodstream. Say Hello to the 100 Trillion Bacteria That Make Up Your Microbiome 2013-05-15T11:00:20Z Blood is drawn from these patients and pumped over a filter infused with an antibiotic that binds to endotoxin, removing the molecule before the blood is returned to patients. Researchers Struggle to Develop New Treatments for Sepsis 2013-03-27T11:45:00.563Z Later that morning, a separate text message asks if it would be possible to test for endotoxins on the day of the execution. Records: 2 people in execution knew drugs hadn’t been tested 2022-05-13T04:00:00Z "The higher the level of endotoxin you're exposed to, the more unstable your asthma becomes." Here's why farm kids have fewer allergies and less asthma 2015-09-03T04:00:00Z The Ghent team then tested bronchial cells from healthy people and found that exposure to endotoxins lowers the levels of the same inflammatory molecules studied in the mice. Dirty farm air may ward off asthma in children 2015-09-03T04:00:00Z Three rat shock models were used here: hemorrhagic shock, peritonitis shock induced by placement of cecal material into the peritoneum, and endotoxin shock. [Research Articles] Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock 2013-01-23T19:55:07.367Z A team at the University of Wisconsin-Madison, headed by engineering professor Nicholas Abbott, has discovered a new means of testing for endotoxins that involves inanimate compounds. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z The reason for that, Shi's team writes, is not entirely clear, as silk workers were not exposed to cotton dust or higher-than-normal endotoxin levels. Lung damage in cotton workers partly reversible 2010-04-08T16:13:00Z But one factor may be endotoxin, a substance produced by bacteria that is known to trigger inflammation in the airways, explained lead researcher Dr. Chris Carlsten, of Vancouver General Hospital in British Columbia, Canada. Study links dogs, not cats, to kids' asthma risk 2010-04-07T18:21:00Z The team got similar results when they repeated the mouse experiments with farm dust, which includes not just endotoxins but other potentially inflammatory fragments from bacteria, fungi, and plants as well. Dirty farm air may ward off asthma in children 2015-09-03T04:00:00Z Despite the success of the lysate assay, scientific teams have explored alternative approaches to testing for endotoxins. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z The Food and Drug Administration requires manufacturers to test every drug and medical device that it certifies for the presence of endotoxins. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z Abbott thought that the geometry of droplets might give them a high sensitivity to lipids, the key components of endotoxins. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z Initial research showed that the endotoxins' lipids did indeed alter the appearance of liquid crystal droplets under a microscope. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z The team first thought that the surfaces of the droplets adsorbed the endotoxins, but the process was too sensitive to justify that explanation. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z Scientists use small amounts of the blood, which is colored blue, to test medicinal drugs and other items for the presence of endotoxins. New Test Puts the Squeeze on Horseshoe Crabs 2011-06-30T19:57:00Z |
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