单词 | disulfiram |
例句 | Only three conventional drugs - disulfiram, naltrexone and acamprosate - are approved to treat alcohol use disorder and there’s been no new drug approvals in nearly 20 years. ‘Magic mushroom’ psychedelic may help heavy drinkers quit 2022-08-24T04:00:00Z Only three conventional drugs — disulfiram, naltrexone and acamprosate — are approved to treat alcohol use disorder and there’s been no new drug approvals in nearly 20 years. ‘Magic mushroom’ psychedelic may help heavy drinkers quit 2022-08-24T04:00:00Z At the moment, Columbia University Medical School in New York is recruiting patients for the first clinical trial of disulfiram for PTLDS. Lyme disease: is a solution on the way? 2019-07-20T04:00:00Z In the 1940s, doctors explored whether disulfiram was useful as a treatment for alcohol abuse. Can I Drink Alcohol While Taking Antibiotics? 2018-06-15T04:00:00Z Liposome encapsulated disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 2017-12-05T05:00:00Z But since then, disulfiram hasn’t gotten much attention for treating cancer, partly because scientists disagreed about how it worked. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z Another study looked at substance abuse treatment programs across the country and found that fewer than 20 percent sustained their use of medications including naltrexone or disulfiram. There are medications that can treat alcoholism, but doctors rarely use them 2017-10-27T04:00:00Z With disulfiram, however, this did not appear to present a problem, she said. Alcoholism drug can 'wake up' dormant HIV to be killed, study finds 2015-11-18T05:00:00Z Hangovers and the anti-alcohol drug disulfiram produce pretty much the same effect. Genetics: No more addictive personality : Nature : Nature Publishing Group 2015-06-23T04:00:00Z But they were more effective than a much older and more widely known medication for alcoholism called Antabuse, or disulfiram. Effective Drugs to Curb Alcoholism Are Ignored, Study Finds 2014-05-13T04:00:00Z However, “big pharma probably won’t be interested” in developing disulfiram for cancer because there’s no patent protection on the drug, Bartek says. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z Medication - Antabuse, or disulfiram, a tablet which makes the taker sick if he or she drinks alcohol. Tough love 2011-07-26T00:13:16Z It’s based on as-yet-unpublished laboratory experiments about the effect of Antabuse, also known as disulfiram, on latent HIV by Robert Siliciano, a professor of medicine at Johns Hopkins in Baltimore. Alcohol, Cocaine Abuse Drug May Hold Clues in AIDS Cure Quest 2011-02-23T09:08:26Z The drug, known generically as disulfiram, reacts with alcohol to induce vomiting in abstainers who backslide and take a drink. Alcoholics May Stop at One Drink With Help From Lundbeck Pill 2010-12-22T23:18:16Z Although some approved cancer drugs and others in development interfere with the same protein cleanup process, known as the ubiquitin-proteasome system, disulfiram targets only a specific molecular complex within this machinery. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z Starting in the 1970s, scientists found that disulfiram killed cancer cells and slowed tumor growth in animals. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z The researchers also confirmed that disulfiram slows the growth of breast cancer tumors in mice, particularly if combined with a copper supplement, which was already known to enhance its effects. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z They then showed that when the mice broke down disulfiram, its main metabolite, ditiocarb, forms a complex with copper that blocks the machinery that cells use to dispose of misfolded and unneeded proteins. An old drug for alcoholism finds new life as cancer treatment 2017-12-06T05:00:00Z |
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