英语词汇“X-linked”造句子简单的方法、技巧、例句及翻译-英语例句辞典

I did not tell her that she is the carrier of the defective gene, X-linked inheritance a defining characteristic of Duchenne. Our beautiful sons could die before us 2014-08-16T04:00:00Z

When a gene being examined is present on the X, but not the Y, chromosome, it is X-linked. Concepts of Biology 2013-04-25T00:00:00Z

An infant patient exhibits symptoms of neonatal ALD, which are difficult to distinguish from the X-linked form of the disease. Biology for AP Courses 2022-06-09T00:00:00Z

How can a female carrier of an X-linked recessive disorder have a daughter who is affected? Anatomy and Physiology 2013-06-19T00:00:00Z

X-linked hypophosphatemia, as the name suggests, is a disease that is inherited on the X chromosome. The Toddler Was Bowlegged, Her Gait Awkward. What Was It? 2021-12-02T05:00:00Z

This shutdown ensures that the body does not express more X-linked genes than it should. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z

Eye color in Drosophila, the common fruit fly, was the first X-linked trait to be identified. Concepts of Biology 2013-04-25T00:00:00Z

Eye color in Drosophila was one of the first X-linked traits to be identified. Biology for AP Courses 2022-06-09T00:00:00Z

When an abnormal allele for a gene that occurs on the X chromosome is dominant over the normal allele, the pattern is described as X-linked dominant. Anatomy and Physiology 2013-06-19T00:00:00Z

The genetic test came back positive; the child had X-linked hypophosphatemia. The Toddler Was Bowlegged, Her Gait Awkward. What Was It? 2021-12-02T05:00:00Z

In women with lupus, for instance, some genes are active on both X copies, and this higher activity correlates with disease severity: sicker lupus patients have more active X-linked genes than women with milder disease. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z

Males are said to be hemizygous, in that they have only one allele for any X-linked characteristic. Concepts of Biology 2013-04-25T00:00:00Z

Males are said to be hemizygous, because they have only one allele for any X-linked characteristic. Biology for AP Courses 2022-06-09T00:00:00Z

X-linked recessive inheritance is much more common because females can be carriers of the disease yet still have a normal phenotype. Anatomy and Physiology 2013-06-19T00:00:00Z

“Our favorite hypothesis is that it is an X-linked recessive trait,” Casanova says. Hidden immune weakness found in 14% of gravely ill COVID-19 patients 2020-09-24T04:00:00Z

In fact, many X-linked genes have been directly tied to autoimmune disease. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z

In an X-linked cross, the genotypes of F1 and F2 offspring depend on whether the recessive trait was expressed by the male or the female in the P generation. Concepts of Biology 2013-04-25T00:00:00Z

Because human males need to inherit only one recessive mutant X allele to be affected, X-linked disorders are disproportionately observed in males. Biology for AP Courses 2022-06-09T00:00:00Z

Diseases transmitted by X-linked recessive inheritance include color blindness, the blood-clotting disorder hemophilia, and some forms of muscular dystrophy. Anatomy and Physiology 2013-06-19T00:00:00Z

But as many as a quarter of X-linked genes can escape this inactivation, giving people with two copies of the chromosome a “double dosage” of the genetic instructions needed to fight disease. All across the United States, the coronavirus is killing more men than women, data show 2020-04-04T04:00:00Z

Typically over time evolution eliminates processes that make it harder for species to reproduce and thrive, and X-linked autoimmunity definitely hinders thriving. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z

These females will pass the disease to half of their sons and will pass carrier status to half of their daughters; therefore, X-linked traits appear more frequently in males than females. Concepts of Biology 2013-04-25T00:00:00Z

Females must inherit recessive X-linked alleles from both of their parents in order to express the trait. Biology for AP Courses 2022-06-09T00:00:00Z

For an example of X-linked recessive inheritance, consider parents in which the mother is an unaffected carrier and the father is normal. Anatomy and Physiology 2013-06-19T00:00:00Z

It is an X-linked recessive genetic disorder, which means that only boys are affected and the mother may be a healthy carrier of the disease. UK newborn baby screening 'not good enough' 2019-07-22T04:00:00Z

Perhaps, Wilson says, X-linked genes and incomplete X inactivation evolved as a way for a woman’s body to flexibly respond to the strange new immune requirements of pregnancy. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z

But a cure for the most common form – X-linked SCID, which is only found in boys – had remained elusive until now. Gene therapy cures infants with ‘bubble boy’ immune disease 2019-04-17T04:00:00Z

When they inherit one recessive X-linked mutant allele and one dominant X-linked wild-type allele, they are carriers of the trait and are typically unaffected. Biology for AP Courses 2022-06-09T00:00:00Z

With X-linked recessive diseases, males either have the disease or are genotypically normal—they cannot be carriers. Anatomy and Physiology 2013-06-19T00:00:00Z

For example, Rett syndrome is an X-linked pervasive developmental disorder characterized by a spectrum of disabilities including abnormal behavior, speech and motor function. Early Life Experience: It's in Your DNA 2018-07-10T04:00:00Z

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. Regeneration of the entire human epidermis using transgenic stem cells 2017-11-07T05:00:00Z

Each study catalogues hundreds of X-linked genes and together the data span two tissue types. Landscape of X chromosome inactivation across human tissues : Nature : Nature Research 2017-10-10T04:00:00Z

Genes that are present on the X but not the Y chromosome are said to be X-linked, such that males only inherit one allele for the gene, and females inherit two. Biology for AP Courses 2022-06-09T00:00:00Z

A daughter can inherit the gene for an X-linked recessive illness when her mother is a carrier or affected, or her father is affected. Anatomy and Physiology 2013-06-19T00:00:00Z

By contrast, boys with the inherited immunodeficiency X-linked agammaglobulinaemia could control such viral infections even though they lacked antibody responses. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z

The majority of children with X-linked severe combined immunodeficiency, or X-SCID, die before the age of one and must live in a "bubble" for protection. Gene therapy treats 'bubble boy' 2014-10-08T04:00:00Z

Mutations in these previously described genes are responsible for the so-called X-linked recessive diseases such as hemophilia and Duchenne muscular dystrophy. 'Female' Chromosome May Leave a Mark on Male Fertility 2013-07-21T18:30:00Z

No, males cannot be the carriers of red-green color blindness, as color blindness is X-linked. Biology for AP Courses 2022-06-09T00:00:00Z

The daughter will be affected by the disease only if she inherits an X-linked recessive gene from both parents. Anatomy and Physiology 2013-06-19T00:00:00Z

The dramatic phenotype was highly reminiscent of that of patients with X-linked agammaglobulinaemia. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z

The observed differences at X-linked promoters arise because of measurable changes in Pol II occupancies and not by chance. [Technical Response] Response to Comments on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:40.283Z

More importantly, we found that the difference in the Pol II occupancy between male X-linked and autosomal genes was ~1.2, which is substantially lower than the ~2-fold increase reported by Conrad . [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z

When a gene being examined is present on the X chromosome, but not on the Y chromosome, it is said to be X-linked. Biology for AP Courses 2022-06-09T00:00:00Z

Or, natural selection may have removed X-linked Denisovan genes that conferred some disadvantage. The Denisova Genome and Guys Banging Rocks 2012-08-30T19:15:00.440Z

Because people with X-linked agammaglobulinaemia are deficient in antibody production but not in cellular immunity, their disease was probably due to a deficiency in B-cell development only. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z

In contrast to this assumption, we demonstrate that the effect of dosage compensation is apparent at the beginning of X-linked genes. [Technical Response] Response to Comments on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:40.283Z

The reduced ratio does not support an initiation-based model but rather is inconclusive regarding the steps in the transcription cycle necessary to achieve a 2-fold increase in male X-linked transcription. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z

Figure 12.13 The son of a woman who is a carrier of a recessive X-linked disorder will have a 50 percent chance of being affected. Biology for AP Courses 2022-06-09T00:00:00Z

Barbash argues that these results are a challenge to our own, implying that X-linked lethal regions from san are not expected. [Technical Response] Response to Comment on ?A Test of the Snowball Theory for the Rate of Evolution of Hybrid Incompatibilities? 2011-09-15T18:25:20.263Z

The second possibility is that the X-linked viability effects are female-specific. [Technical Comment] Comment on ?A Test of the Snowball Theory for the Rate of Evolution of Hybrid Incompatibilities? 2011-09-15T18:25:17.657Z

The most likely explanation for her brothers' condition was X-linked inheritance following a new mutation in their mother. [Essay] Genome-Sequencing Anniversary: A Healthy Son 2011-02-24T19:26:19.233Z

In a corroborating line of evidence, Conrad . examined short RNAs for a panel of genes by quantitative polymerase chain reaction, showing a 2-fold increase at X-linked genes in males compared with females. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z

Among the 156 women who underwent testing because of the risk of an X-linked disorder, the results allowed 41 percent to avoid further, invasive procedures to test for the disorder. 2010-01-18T18:24:00Z

Effect of the erroneous multiplication step on the ratio of Pol II binding on X-linked genes compared with autosomal genes. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z

单词	X-linked
例句	X-linked I did not tell her that she is the carrier of the defective gene, X-linked inheritance a defining characteristic of Duchenne. Our beautiful sons could die before us 2014-08-16T04:00:00Z When a gene being examined is present on the X, but not the Y, chromosome, it is X-linked. Concepts of Biology 2013-04-25T00:00:00Z An infant patient exhibits symptoms of neonatal ALD, which are difficult to distinguish from the X-linked form of the disease. Biology for AP Courses 2022-06-09T00:00:00Z How can a female carrier of an X-linked recessive disorder have a daughter who is affected? Anatomy and Physiology 2013-06-19T00:00:00Z X-linked hypophosphatemia, as the name suggests, is a disease that is inherited on the X chromosome. The Toddler Was Bowlegged, Her Gait Awkward. What Was It? 2021-12-02T05:00:00Z This shutdown ensures that the body does not express more X-linked genes than it should. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z Eye color in Drosophila, the common fruit fly, was the first X-linked trait to be identified. Concepts of Biology 2013-04-25T00:00:00Z Eye color in Drosophila was one of the first X-linked traits to be identified. Biology for AP Courses 2022-06-09T00:00:00Z When an abnormal allele for a gene that occurs on the X chromosome is dominant over the normal allele, the pattern is described as X-linked dominant. Anatomy and Physiology 2013-06-19T00:00:00Z The genetic test came back positive; the child had X-linked hypophosphatemia. The Toddler Was Bowlegged, Her Gait Awkward. What Was It? 2021-12-02T05:00:00Z In women with lupus, for instance, some genes are active on both X copies, and this higher activity correlates with disease severity: sicker lupus patients have more active X-linked genes than women with milder disease. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z Males are said to be hemizygous, in that they have only one allele for any X-linked characteristic. Concepts of Biology 2013-04-25T00:00:00Z Males are said to be hemizygous, because they have only one allele for any X-linked characteristic. Biology for AP Courses 2022-06-09T00:00:00Z X-linked recessive inheritance is much more common because females can be carriers of the disease yet still have a normal phenotype. Anatomy and Physiology 2013-06-19T00:00:00Z “Our favorite hypothesis is that it is an X-linked recessive trait,” Casanova says. Hidden immune weakness found in 14% of gravely ill COVID-19 patients 2020-09-24T04:00:00Z In fact, many X-linked genes have been directly tied to autoimmune disease. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z In an X-linked cross, the genotypes of F1 and F2 offspring depend on whether the recessive trait was expressed by the male or the female in the P generation. Concepts of Biology 2013-04-25T00:00:00Z Because human males need to inherit only one recessive mutant X allele to be affected, X-linked disorders are disproportionately observed in males. Biology for AP Courses 2022-06-09T00:00:00Z Diseases transmitted by X-linked recessive inheritance include color blindness, the blood-clotting disorder hemophilia, and some forms of muscular dystrophy. Anatomy and Physiology 2013-06-19T00:00:00Z But as many as a quarter of X-linked genes can escape this inactivation, giving people with two copies of the chromosome a “double dosage” of the genetic instructions needed to fight disease. All across the United States, the coronavirus is killing more men than women, data show 2020-04-04T04:00:00Z Typically over time evolution eliminates processes that make it harder for species to reproduce and thrive, and X-linked autoimmunity definitely hinders thriving. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z These females will pass the disease to half of their sons and will pass carrier status to half of their daughters; therefore, X-linked traits appear more frequently in males than females. Concepts of Biology 2013-04-25T00:00:00Z Females must inherit recessive X-linked alleles from both of their parents in order to express the trait. Biology for AP Courses 2022-06-09T00:00:00Z For an example of X-linked recessive inheritance, consider parents in which the mother is an unaffected carrier and the father is normal. Anatomy and Physiology 2013-06-19T00:00:00Z It is an X-linked recessive genetic disorder, which means that only boys are affected and the mother may be a healthy carrier of the disease. UK newborn baby screening 'not good enough' 2019-07-22T04:00:00Z Perhaps, Wilson says, X-linked genes and incomplete X inactivation evolved as a way for a woman’s body to flexibly respond to the strange new immune requirements of pregnancy. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z But a cure for the most common form – X-linked SCID, which is only found in boys – had remained elusive until now. Gene therapy cures infants with ‘bubble boy’ immune disease 2019-04-17T04:00:00Z When they inherit one recessive X-linked mutant allele and one dominant X-linked wild-type allele, they are carriers of the trait and are typically unaffected. Biology for AP Courses 2022-06-09T00:00:00Z With X-linked recessive diseases, males either have the disease or are genotypically normal—they cannot be carriers. Anatomy and Physiology 2013-06-19T00:00:00Z For example, Rett syndrome is an X-linked pervasive developmental disorder characterized by a spectrum of disabilities including abnormal behavior, speech and motor function. Early Life Experience: It's in Your DNA 2018-07-10T04:00:00Z A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. Regeneration of the entire human epidermis using transgenic stem cells 2017-11-07T05:00:00Z Each study catalogues hundreds of X-linked genes and together the data span two tissue types. Landscape of X chromosome inactivation across human tissues : Nature : Nature Research 2017-10-10T04:00:00Z Genes that are present on the X but not the Y chromosome are said to be X-linked, such that males only inherit one allele for the gene, and females inherit two. Biology for AP Courses 2022-06-09T00:00:00Z A daughter can inherit the gene for an X-linked recessive illness when her mother is a carrier or affected, or her father is affected. Anatomy and Physiology 2013-06-19T00:00:00Z By contrast, boys with the inherited immunodeficiency X-linked agammaglobulinaemia could control such viral infections even though they lacked antibody responses. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z The majority of children with X-linked severe combined immunodeficiency, or X-SCID, die before the age of one and must live in a "bubble" for protection. Gene therapy treats 'bubble boy' 2014-10-08T04:00:00Z Mutations in these previously described genes are responsible for the so-called X-linked recessive diseases such as hemophilia and Duchenne muscular dystrophy. 'Female' Chromosome May Leave a Mark on Male Fertility 2013-07-21T18:30:00Z No, males cannot be the carriers of red-green color blindness, as color blindness is X-linked. Biology for AP Courses 2022-06-09T00:00:00Z The daughter will be affected by the disease only if she inherits an X-linked recessive gene from both parents. Anatomy and Physiology 2013-06-19T00:00:00Z The dramatic phenotype was highly reminiscent of that of patients with X-linked agammaglobulinaemia. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z The observed differences at X-linked promoters arise because of measurable changes in Pol II occupancies and not by chance. [Technical Response] Response to Comments on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:40.283Z More importantly, we found that the difference in the Pol II occupancy between male X-linked and autosomal genes was ~1.2, which is substantially lower than the ~2-fold increase reported by Conrad . [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z When a gene being examined is present on the X chromosome, but not on the Y chromosome, it is said to be X-linked. Biology for AP Courses 2022-06-09T00:00:00Z Or, natural selection may have removed X-linked Denisovan genes that conferred some disadvantage. The Denisova Genome and Guys Banging Rocks 2012-08-30T19:15:00.440Z Because people with X-linked agammaglobulinaemia are deficient in antibody production but not in cellular immunity, their disease was probably due to a deficiency in B-cell development only. Immunology: Fifty years of B lymphocytes 2015-01-05T05:00:00Z In contrast to this assumption, we demonstrate that the effect of dosage compensation is apparent at the beginning of X-linked genes. [Technical Response] Response to Comments on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:40.283Z The reduced ratio does not support an initiation-based model but rather is inconclusive regarding the steps in the transcription cycle necessary to achieve a 2-fold increase in male X-linked transcription. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z Figure 12.13 The son of a woman who is a carrier of a recessive X-linked disorder will have a 50 percent chance of being affected. Biology for AP Courses 2022-06-09T00:00:00Z Barbash argues that these results are a challenge to our own, implying that X-linked lethal regions from san are not expected. [Technical Response] Response to Comment on ?A Test of the Snowball Theory for the Rate of Evolution of Hybrid Incompatibilities? 2011-09-15T18:25:20.263Z The second possibility is that the X-linked viability effects are female-specific. [Technical Comment] Comment on ?A Test of the Snowball Theory for the Rate of Evolution of Hybrid Incompatibilities? 2011-09-15T18:25:17.657Z The most likely explanation for her brothers' condition was X-linked inheritance following a new mutation in their mother. [Essay] Genome-Sequencing Anniversary: A Healthy Son 2011-02-24T19:26:19.233Z In a corroborating line of evidence, Conrad . examined short RNAs for a panel of genes by quantitative polymerase chain reaction, showing a 2-fold increase at X-linked genes in males compared with females. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z Among the 156 women who underwent testing because of the risk of an X-linked disorder, the results allowed 41 percent to avoid further, invasive procedures to test for the disorder. 2010-01-18T18:24:00Z Effect of the erroneous multiplication step on the ratio of Pol II binding on X-linked genes compared with autosomal genes. [Technical Comment] Comment on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” 2013-04-18T17:55:22.137Z
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