单词 | transferrin |
例句 | The virus exploits the host’s transferrin, a membrane-bound protein used for iron transport, to attach to the cell. Biology for AP Courses 2022-06-09T00:00:00Z Iron is bound to a protein called transferrin in the blood. Anatomy and Physiology 2013-06-19T00:00:00Z As the two Utah scientists were studying these evolutionary changes, researchers at the National Institutes of Health published the molecular details of how TbpA grabs transferrin. An Evolutionary Battle Against Bacteria 2014-12-11T05:00:00Z In their most recent study, published today in Science Translational Medicine1, the researchers adjusted the strength with which the antibody binds to transferrin. Alzheimer's drug sneaks through blood-brain barrier 2014-11-04T05:00:00Z The subterfuge involves the transferrin receptor, a docking site used to transport iron into the brain. Fooling Brain Defenses To Deliver an Alzheimer's Drug 2014-01-13T20:45:57.746Z That design, similar to the molecular structure of the natural transferrin protein that binds to the receptor, seems to allow unhindered passage. Fooling Brain Defenses To Deliver an Alzheimer's Drug 2014-01-12T14:45:00.450Z Both enable the oxidation of iron from Fe2+ to Fe3+, a form in which it can be bound to its transport protein, transferrin, for transport to body cells. Anatomy and Physiology 2013-06-19T00:00:00Z Dr. Barber and Dr. Elde were able to reconstruct the history of transferrin. An Evolutionary Battle Against Bacteria 2014-12-11T05:00:00Z Crucially, the antibody binds more tightly to BACE1 than to transferrin, and this pulls it off the blood vessel and into the brain. Alzheimer's drug sneaks through blood-brain barrier 2014-11-04T05:00:00Z That design, similar to the molecular structure of the natural transferrin protein that attaches to the receptor, seems to allow unhindered passage. Fooling Brain Defenses To Deliver an Alzheimer's Drug 2014-01-13T20:45:57.746Z If tests show that transferrin, the protein that transports iron through the bloodstream, is saturated with iron, that virtually clinches the diagnosis. Hemochromatosis, iron-overload disease, is more common than previously thought 2013-09-02T21:56:36Z They knew that iron crosses easily into the brain, so they made the antibody specifically target transferrin receptors, which transport iron across the blood brain barrier. Study finds way to get antibody therapies into brain 2011-05-26T00:29:28Z To move iron atoms from one cell to another, we seal them inside a kind of molecular lockbox, called transferrin. An Evolutionary Battle Against Bacteria 2014-12-11T05:00:00Z The key, he says, seems to be engineering the antibody so that it binds neither too tightly nor too loosely to transferrin. Alzheimer's drug sneaks through blood-brain barrier 2014-11-04T05:00:00Z Iron in the bloodstream is bound to a bulky molecule called transferrin. Tricking the Brain Into Taking Its Medicine 2011-05-25T19:35:58Z The Strathclyde-led team investigated ways of doing so with the use of the plasma protein transferrin, which carries iron through the blood. Cancer gene therapy result hailed 2010-04-21T11:53:00Z One end binds loosely to transferrin and uses the protein to transport itself into the brain. Alzheimer's drug sneaks through blood-brain barrier 2014-11-04T05:00:00Z Dr. Malik suggested that this treatment would be even more effective if scientists used the evolutionary history of transferrin as a guide for designing transferrin that the bacteria can’t attack. An Evolutionary Battle Against Bacteria 2014-12-11T05:00:00Z |
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