It's a big issue. A very big issue.

这是一个大问题。一个非常重要的问题。

So there are two big issues here.

所以这引起两个很大的争议。

It's clearly a big issue on campus. It's clearly a big issue across the country.

这显然是学校的大事，也是美国的大事。

The bigger issue is processing and purifying.

更大的问题是如何加工和净化。

He called the fires " a big issue."

他称火灾是“一个大问题”。

Well, boredom on the playground is a big issue.

操场无趣乏味，这是个大问题。

Another big issue dividing the countries is Venezuela.

两国存在分歧的另一个重要问题涉及委内瑞拉。

The biggest issue has been the social distancing.

社交距离一直是最大的问题。

And that's a really, really big issue.

这是一个非常非常大的问题。

And that's a big issue in Tehran.

这在伊朗看来是个大问题。

And, of course, Ukraine was a big issue.

当然，乌克兰也是此次会谈的一个重要议题。

Okay, well, we have bigger issues.

好吧 现在有个更严重的问题。

Human elephant conflict is a big issue in India.

人象冲突在印度是一个大问题。

Which really does lead to our biggest issue… these.

这确实带来了我们面临的最大的问题… … 这些东西（将何去何从？）。

We need to deal with this big issue, right?

我们需要解决这个重要议题，对吧？

But there's one big issue holding it back.

但有一个大问题阻碍着它。

NPR's John Ydstie says big issues remain unresolved.

据NPR新闻的John Ydstie报道，重大问题仍旧没有解决。

Demand for shots is now a bigger issue than supply.

现在，接种需求比疫苗供应更重要。

The environment wasn't such a big issue back then.

环境曾经不是什么大问题。

It's their biggest selling issue for simply ages, apparently.

这显然是他们多年来最畅销的一期。