Well, actually pigmented gallstones are made of unconjugated bilirubin.

然而，事实上胆红素结石是由非结合胆红素构成的。

The brownness is due to this mix of unconjugated or hydrolyzed bilirubin and phospholipids.

结石的褐色源自未结合胆红素，或水解的胆红素，和磷脂的混合物。

Usually though, bile salts bind up the calcium ions and keep them from binding with and precipitating unconjugated bilirubin.

通常情况下，胆盐会结合钙离子，以此阻止钙离子与非结合胆红素结合并沉淀。

Recycling of that heme group yields unconjugated bilirubin, which at high concentration can cause scleral icterus, jaundice, and bilirubin gall stones.

亚铁血红素的循环利用会产生非结合胆红素，其浓度过高会导致巩膜黄染、黄疸与胆红素胆结石。

And, since the liver usually conjugates bilirubin, there'll be increased unconjugated bilirubin in the blood from a less-functional liver and that can lead to jaundice.

还有，由于肝脏能把血液中过多的非结合胆红素转变成结合胆红素，肝脏功能减退还会引起的血液中非结合胆红素升高，引发黄疸。

Well the vast majority is conjugated, but there is a small amount of unconjugated bilirubin in bile, only about 1-2% of total bilirubin, which is only 1% of bile.

其实胆汁中绝大部分是结合胆红素，但仍有少量的非结合胆红素，仅占总胆红素的1-2%，占胆汁的1%。

With extravascular hemolysis, we have macrophages eating up red blood cells more than normal and unconjugated bilirubin production is ramped up, which is conjugated by the liver and sent to the gallbladder.

血管外溶血时，巨噬细胞吞噬红细胞，较正常时更多，进而加速了非结合胆红素的产生，非结合胆红素在肝脏转变为结合胆红素，并输送至胆囊。