Bulgarian psychiatrist Nikola Schipkowensky said that tricyclic antidepressants were inducing the disease to " change to a more chronic course."

保加利亚精神病医师 Nikola Schipkowensky 说，三环类抗抑郁药物会使抑郁症状沿着“更加长期化的过程”演化。

Unfortunately, tricyclics also interfere with a lot of other signalling mechanisms, which meant people could easily kill themselves by overdosing.

不幸的是，三环化合物还会干扰许多其他信号机制，这意味着人们很容易因服药过量而自杀。

Tricyclics, an early generation of them, blocked protein channels called serotonin transporters through which serotonin is reabsorbed by a neuron after it has done its job.

三环化合物，它们的早期一代，阻断了称为血清素转运蛋白的蛋白质通道，血清素通过该通道在完成其工作后被神经元重新吸收。