When are you gonna start doing something with that big brain of yours?

你什么时候才能把你的脑袋瓜用在正地方？

In the last sentence, the phrase take up means to start doing something regularly as a habit.

在最后一句话里，开始从事的意思是开始把某事当做习惯来定期做。

And the beginning of the year seems like a good time to start doing something to improve your health.

新年伊始似乎是开始做某事来改善健康的好时机。

So that really triggered me to start doing something about it.

所以这真的触发了我开始做一些事情。

We also use " set up shop" as a slang expression, it means to start doing something like a professional, but depends on the context for that.

我们还使用“set up shop” 作为俚语表达，意思是开始像专业人士一样做某事， 但这取决于上下文。

" To form a habit" means to create a new habit – to start doing something new so that it becomes a habit in the future for you.

“To form a habit”的意思是养成新的习惯——开始做一些新的事情，让它成为你未来的习惯。

And, and then I started having kids and I don't know just at my older age, I was like I need to start doing maybe something and moisturizing.

而且，然后我开始生孩子，我不知道只是在我年纪大的时候，我觉得我需要开始做点什么，保湿。

And so I was at home and feeling like, OK, if I'm going to stay productive and stay positive, I need to start doing something creative every day.

所以我在家里感觉，好吧，如果我要保持高效和积极， 我需要开始每天做一些有创意的事情。