He would start by striking at the heart  of Lugal-zage-si's conquests – Uruk.

他将从打击 Lugal-zage-si 征服的中心——乌鲁克开始。

But if information is lost, this raises so serious problem that strikes at the heart of our understanding of science.

但如果信息丢失了 就会引发严重的问题 冲击我们对科学的理解。