Osteosarcomas arise from osteoblasts of different sizes - called pleomorphic - and these cells produce too much osteoid tissue.

骨肉瘤起源于大小不同的成骨细胞（多形性）；这些细胞会产生过多的类骨组织。

To build bone, osteoblasts secrete osteoid, which is an organic matrix made of type 1 collagen.

在构建骨的过程中，成骨细胞分泌类骨质，它是一种由1型胶原组成的有机质。

In osteoid osteomas, the nidi are smaller than 1.5cm in diameter and are often surrounded by a ring of sclerotic bone tissue.

在骨样骨瘤中，癌巢直径通常小于1.5cm，并且通常被硬化的骨组织包围（边缘硬化）。

In comparison, osteoid osteomas typically affect the diaphysis of long bones like the tibia, and don't usually erode the surrounding bone.

相比之下，骨样骨瘤通常影响长骨骨干，例如胫骨，并且一般不侵蚀周围骨骼。

Both of these tumors classically form a nidus – which is a disorganized mix of small blood vessels, tiny rods of bone called trabeculae, and unmineralized bony tissue called osteoid.

通常这两种肿瘤形成癌巢：癌巢是小血管、小棒状骨（小梁骨）、未矿化骨（即类骨质）等无组织的构成。

Some unique symptoms are that the pain of osteoid osteoma typically gets worse at night, while osteochondromas and osteoblastomas sometimes press against spinal nerves, causing numbness and limb weakness.

一些独特的症状如骨样骨瘤的疼痛通常会在夜间加剧，而骨软骨瘤、成骨细胞瘤有时会压迫脊神经，引起麻木和四肢无力。