A sudden drop in supplies of certain chemicals could knock the bottom out of the engineering industry.

【knock】某些化学品供应的突然减少会造成工程行业的不景气。

This story of brothels and casinos has absolutely knocked the bottom out of his organization and they're all running around like scalded cats.

这青楼和赌场的故事， 绝对把他的组织给打得落花流水， 都像被烫伤的猫一样四处逃窜。