In 1990, a family with an inherited speech disorder known as verbal dyspraxia drew the attention of genetics researchers.

1990年，患有遗传性语言障碍（verbaldyspraxia）的一家人引起了基因学者的注意。

Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.

甲基丙二酸血症是由于甲基丙二酰辅酶A变位酶或其辅酶腺苷钴胺素缺陷所致的一种遗传性代谢疾病。