In IgA nephropathy, though, there is abnormal glycosylation of these serine and threonine residues, causing them to be galactose-deficient.

而在IgA肾病中，有一系列丝氨酸、苏氨酸残基异常糖基化，导致它们无法连接半乳糖。

IgA nephropathy is therefore a type III hypersensitivity disorder, meaning that pathology and inflammation will happen at the site the immune complexes deposit, not where they are formed.

因此IgA肾病是一种III型超敏反应，意味着病理和炎症反应会发生在免疫复合物沉积的地方，而不是发生在免疫复合物形成的地方。

IgA nephropathy, sometimes known as Berger disease, is the most common form of nephropathy worldwide, and it happens when an abnormal IgA forms and deposits in the kidneys, causing kidney damage.

IgA肾病，有时也叫Berger病，是全球最常见的肾病；该病有异常IgA形成，沉积于肾，造成肾损伤。