Most are designed to target rare genetic diseases, including haemophilia B, where mutation causes problems with blood clotting.

大多数药物旨在针对罕见的遗传疾病，包括 B 型血友病，这种疾病的突变会导致凝血问题。

This means genetic diseases such as haemophilia, muscular dystrophy and cancers, in principle, might be " corrected" by editing the DNA of human embryos.

这意味着血友病、肌肉萎缩症和癌症等遗传疾病原则上可以通过编辑人类胚胎的 DNA 得到“纠正”。

To prevent complications from an existing blood or bleeding disorder, such as sickle cell disease, thalassemia, or anaemia caused by kidney disease, haemophilia, or von Willebrand disease.

预防现有血液或出血性疾病的并发症，如镰状细胞病、地中海贫血或由肾脏疾病、血友病或血管性血友病引起的贫血。

So far, the new generation of genomic medicines have been eye-wateringly expensive—a shot of Hemgenix, a haemophilia B gene-therapy, costs $3.5m, around a million dollars more than Casgevy.

到目前为止，新一代基因药物的价格令人瞠目结舌，一剂血友病 B 基因治疗药物 Hemgenix 就要花费 350 万美元，比 Casgevy 贵出约 100 万美元。

And I guess I started modifying my behaviour somewhat because the haemophilia treatment centre I was calling in to to get my medication, you'd get various brands of it and I was frankly nervous of American brands.

我想我开始稍微改变我的行为是因为我打电话到血友病治疗中心拿药，你会得到各种品牌的药物， 坦率地说，我对美国品牌感到紧张。