In general, changes in climate occur when the energy balance of the Earth is disturbed.

一般来说，当地球的能量平衡被打破时，气候就会发生变化。

Google Ngrams is an app that shows general changes in English usage by searching all the words in Google's digital books.

Google Ngrams 是一款应用程序，它通过搜索 Google 数字图书中的所有单词来显示英语用法的一般变化。

Besides, the disorders of qi, blood and body fluid, internal pathogenic substances (known as " five internal excess" ) as well as the dysfunction of meridians and viscera are also important factors responsible for various general or local pathological changes.

此外，气、血、津液、内在病理物质(称为" 五生无邪" )以及经络和脏腑功能障碍也是导致各种全身或局部病理变化的重要因素。