Coarse crackles occur when there's pulmonary fibrosis, or scarring in the lungs.

当肺纤维化或肺部疤痕形成时，会出现粗湿啰音。

Down syndrome, cystic fibrosis, spina bifida.

唐氏综合症，囊胞性纤维症，脊柱裂。

They also increase collagen synthesis and fibrosis around the eyes.

它们也会增加眼周胶原形成和纤维化。

Sarah Murnaghan was diagnosed with cystic fibrosis when she was a baby.

在莎拉·穆娜汉还是个婴儿的时候被诊断出患有囊性纤维化。

Instead, one idea is to use this technique to help cystic fibrosis patients.

相反，其中一种想法是，利用这项技术帮助囊性纤维病患者。

Importantly, cystic fibrosis is the main cause of chronic pancreatitis in children.

有一点很重要，即囊性纤维化是儿童慢性胰腺炎的主要病因。

Sarah Murnaghan needed the transplant because her own lung has been destroyed by cystic fibrosis.

萨拉·默纳汉因患囊性肺纤维而需要接受移植手术。

And that's usually a sign of a really serious problem, like pancreatic cancer or cystic fibrosis.

那通常是是重大疾病的一个标志，例如胰腺癌或者囊胞性纤维症。

It aims to speed up the diagnosis of a large number of childhood conditions including cystic fibrosis.

该项目旨在加快对包括囊性纤维化在内的大量儿童疾病的诊断。

For example, genetic testing may be used to confirm a diagnosis of cystic fibrosis or Huntington's disease.

例如，基因检测可用于确认囊性纤维化或亨廷顿病的诊断。

Lung transplants are done mostly for chronic lung diseases like pulmonary fibrosis, cystic fibrosis, or COPD, chronic obstructive pulmonary disease.

肺移植主要用于治疗慢性肺部疾病，如肺纤维化、囊性纤维化或慢性阻塞性肺疾病。

In particular, it's implicated in oxidative stress and myocardial fibrosis — an abnormal thickening of the heart valves.

醛固酮与氧化应激和心肌纤维化（心脏瓣膜异常增厚）尤其相关。

I did two years genetics research in cystic fibrosis. I've pretty much seen it all, Dr. Grey.

我做了两年的遗传学胆囊纤维症研究。我知道的很清楚，Grey 医生。

Also, fibrosis starts to develop, and the limbs harden and increase in size.

此外，在第二期，纤维化开始发展，肢体增粗变硬、体积增大。

In addition to that, Bromocriptine has been associated with pulmonary and cardiac fibrosis.

除此之外，溴隐亭还与肺和心脏纤维化有关。

This gradual process of healthy pancreatic tissue getting replaced by misshaped ducts, fibrosis, and calcium deposits is chronic pancreatitis.

健康的胰腺组织逐渐被畸形的导管、纤维组织和钙沉积物取代，这个渐进性的过程就是慢性胰腺炎。

Those who study cystic fibrosis had known all this for a long time.

那些研究囊性纤维化的人早就知道这一切。

Cystic fibrosis is caused by mutation in CFTR.

囊性纤维化是由 CFTR 突变引起的。

First, the tumor causes local inflammation, which causes damage to the suspensory ligaments and lactiferous ducts, resulting in their fibrosis.

首先，肿瘤可能导致局部炎症，会导致悬韧带和输乳管受损，继而纤维化。

Chronic pancreatitis is inflammation due to irreversible changes to the pancreatic structure, like fibrosis, atrophy and calcification.

慢性胰腺炎是胰腺结构发生不可逆改变导致的炎症，例如纤维化、萎缩和钙化。