The staging is based on the extent of nodal and extranodal involvement.

分期是基于淋巴结和结外受累的程度。

If there's extranodal involvement of the gastrointestinal tract, it can cause bowel obstruction.

如果有胃肠道受累，可引起肠梗阻。

If there's extranodal involvement of the bone marrow, it can cause fatigue, easy bruising, or recurrent infections.

如果累及骨髓，它可以导致疲劳、容易瘀紫，或复发感染。

In individuals in Africa, Burkitt lymphoma classically causes extranodal involvement of the jaw and is often associated with Epstein Barr virus infection.

在非洲的患者中，伯基特淋巴瘤通常引起颌骨的结外受累，并常与EB病毒感染有关。

And if there's extranodal involvement of the spinal cord, it can cause weakness and a loss of sensation - usually in the legs.

如果累及脊髓，会导致肢体无力和感觉丧失，通常在腿部。

Lymphomas can happen anywhere in the body, though, and when they develop in other tissues or organs - like the stomach or skin - they're called extranodal lymphomas.

不过，淋巴瘤可以发生在身体的任何部位，当它们发生在其他组织或器官中时，比如胃或皮肤，被称为结外淋巴瘤。

In contrast, in individuals outside Africa, Burkitt lymphoma classically causes extranodal involvement of the abdomen - most often at the ileocecal junction - and is less frequently associated with Epstein Barr virus infection.

相比之下，在非洲以外区域的患者中，伯基特淋巴瘤通常引起腹部的结外受累，最常在回盲部，并且较少与EB病毒感染相关。