| 单词 | single-stranded |
| 例句 | However, it was previously unknown whether and how cells sense and resolve crosslinking damage to single-stranded RNA. Colliding ribosomes activate RNA repair 2023-11-15T05:00:00Z These short, single-stranded segments of DNA or RNA are called aptamers, also known as "chemical antibodies." Novel hydrogel finds new aptamers, or 'chemical antibodies,' in days 2023-10-16T04:00:00Z Aptamers are single-stranded pieces of DNA that bind to target proteins and are able to modulate signaling cascades during cell differentiation when a stem cell commits to a specific functional role or phenotype. DNA aptamer finds novel application in regulating cell differentiation 2023-10-10T04:00:00Z He began to look for human papillomavirus DNA in cells from cervical cancer patients using a gene probe, a short piece of single-stranded DNA designed to bind to a specific sequence in the HPV genome. Harald zur Hausen, Nobelist Who Found Cause of Cervical Cancer, Dies at 87 2023-06-09T04:00:00Z RNA exists as a single-stranded molecule rather than a double- stranded helix. Concepts of Biology 2013-04-25T00:00:00Z However, it was previously unknown whether and how cells sense and resolve crosslinking damage to single-stranded RNA. Colliding ribosomes activate RNA repair 2023-11-15T05:00:00Z As a member of the Caliciviridae family, it is a single-stranded RNA virus that doesn’t rely on an exterior “envelope” for protection. How to Avoid the Dreaded Norovirus 2023-03-14T04:00:00Z They convert their single-stranded genomes into a dsDNA intermediate before transcription to mRNA can occur. Biology for AP Courses 2022-06-09T00:00:00Z It cuts the strand of DNA between specific bases, leaving single-stranded overhangs. Miller & Levine Biology 2018-01-01T00:00:00Z For one thing, unlike DNA, most types of RNA, including mRNA, are single-stranded and contain no complementary strand. Anatomy and Physiology 2013-06-19T00:00:00Z The coronavirus is a tiny, single-stranded RNA virus, which may have aided its ability to become airborne. How Serious Is Monkeypox? 2022-05-23T04:00:00Z Like other single-stranded RNA viruses, norovirus has a high mutation rate. How to Avoid the Dreaded Norovirus 2023-03-14T04:00:00Z Viroids are single-stranded RNA pathogens that infect plants. Biology for AP Courses 2022-06-09T00:00:00Z As for pterosaurs, researchers had previously reported their bodies were covered in pycnofibers, single-stranded structures that formed a “fuzz,” presumably for warmth. Pterosaurs may have flaunted colorful plumage long before the reign of dinosaurs 2022-04-20T04:00:00Z Messenger RNA is a single-stranded RNA molecule that provides instructions on protein production. Do mRNA vaccines affect my DNA? 2021-05-05T04:00:00Z These vaccines use synthetic versions of mRNA, a single-stranded RNA molecule that complements one of the DNA strands in a gene. Scientists say the technology behind COVID-19 mRNA vaccines could be adapted to an HIV vaccine 2021-04-09T04:00:00Z Scientists create synthetic versions of mRNA, a single-stranded RNA molecule that complements one of the DNA strands in a gene. Doctors, Pharma are already talking about booster shots to protect against mutant COVID-19 strains 2021-03-17T04:00:00Z Single-strand binding proteins coat the single strands of DNA near the replication fork to prevent the single-stranded DNA from winding back into a double helix. Biology for AP Courses 2022-06-09T00:00:00Z By contrast, mRNA vaccines directly introduce a modified version of a single-stranded RNA molecule that complements one of the DNA strands in a gene into the bodies' cells. Why the AstraZeneca/Oxford coronavirus vaccine could be a game-changer 2021-02-16T05:00:00Z Both the Modern and Pfizer/BioNTech vaccines are mRNA vaccines, meaning that they use a single-stranded RNA molecule and inject it into the body. WHO: Coronavirus vaccines should not be given to pregnant people 2021-01-28T05:00:00Z They are infamous partly because a single-stranded RNA genome is subject to frequent mutation as the virus replicates, and such mutation supplies a richness of random genetic variation upon which natural selection can work. How viruses shape our world 2021-01-14T05:00:00Z For these, scientists create synthetic versions of mRNA, a single-stranded RNA molecule that complements one of the DNA strands in a gene. Why mRNA vaccines like those being made to treat coronavirus are a quantum leap for biotech 2020-12-06T05:00:00Z Single-strand binding proteins bind to the single-stranded DNA near the replication fork to keep the fork open. Biology for AP Courses 2022-06-09T00:00:00Z In the 1980s, researchers studying a soil bacterium were puzzled to find many copies of short sequences of single-stranded DNA littering the cells. Microbes’ mystery DNA helps defeat viruses—and has genome-editing potential 2020-11-11T05:00:00Z The broken DNA is processed to generate single-stranded overhangs termed presynaptic DNA. Demystifying the D-loop during DNA recombination 2020-10-13T04:00:00Z But those enzymes, called cytidine deaminases, normally act only on single-stranded DNA. Scientists make precise edits to mitochondrial DNA for first time 2020-07-07T04:00:00Z They are sacks of code — double- or single-stranded, DNA or RNA — and sometimes called capsid-encoding organisms, or CEOs. Monster or Machine? A Profile of the Coronavirus at 6 Months 2020-06-02T04:00:00Z Many restriction endonucleases make staggered cuts in the two strands of DNA, such that the cut ends have a 2- or 4-base single-stranded overhang. Biology for AP Courses 2022-06-09T00:00:00Z RNA is a single-stranded messenger molecule that normally delivers genetic instructions from DNA, coiled up inside cells, to protein-making factories that sit outside cells. The hunt for a coronavirus vaccine – a perilous and uncertain path 2020-04-24T04:00:00Z In this case, the structure is further stabilized by binding of the displaced strand to the secondary DNA-binding site, as well as by base-pairing interactions between the complementary strand and the presynaptic single-stranded DNA. Demystifying the D-loop during DNA recombination 2020-10-13T04:00:00Z Next the scientists deployed single-stranded DNA molecules, each only 16 bases long, that latched onto corresponding sequences of bases within those bubbles. “Punch Card” DNA Could Mean Cheaper High-Capacity Data Storage 2020-04-08T04:00:00Z An exonuclease enzyme is used to digest the ends of the DNA and leave complementary single-stranded sequences that readily pair up. How to build a genome 2020-02-23T05:00:00Z Explain why retroviral DNA rather than the genomes of single-stranded or double-stranded DNA or single- stranded RNA viruses are found in host DNA. Biology for AP Courses 2022-06-09T00:00:00Z A foundational tenet in molecular genetics — its central dogma — was that cellular machinery faithfully transcribes genetic information from a double-stranded DNA template into a single-stranded RNA messenger, which is then translated into a protein. Step aside CRISPR, RNA editing is taking off 2020-02-03T05:00:00Z Three nucleotides of the stretched single-stranded DNA are bound to each RecA protein within the primary site, whereas each RecA protein binds to five nucleotides of DNA in its secondary site. Demystifying the D-loop during DNA recombination 2020-10-13T04:00:00Z Finally, VSV is a model for many other single-stranded RNA viruses. Scientists Program CRISPR to Fight Viruses in Human Cells 2019-10-23T04:00:00Z Although the stability of double-stranded RNA means it is currently the dominant approach, single-stranded RNA is also a potential therapeutic candidate. The challenge of delivering RNA-interference therapeutics to their target cells 2019-10-15T04:00:00Z The process is triggered when a single-stranded DNA that is complementary to the timing code is added to the system. DNA tags used to image sugar-bearing proteins on cells 2018-09-03T04:00:00Z For the tracers, her group developed synthetic single-stranded DNA molecules, about 80 to 100 “letters” long and with random sequences. How DNA Could Unlock the Mysteries of Melting Glaciers and Ice Sheets 2017-12-22T05:00:00Z In DNA origami, a nanostructure is assembled from a very long single-stranded scaffold molecule held in place by many short single-stranded staple oligonucleotides. Biotechnological mass production of DNA origami 2017-12-05T05:00:00Z They dose the cells with single-stranded guide DNA, which does not set off the destructive mechanism. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Research suggests the other half of the double RNA strand isn’t necessary for the interference action1,2, and single-stranded RNA can also be chemically stabilized to survive inside the body. The challenge of delivering RNA-interference therapeutics to their target cells 2019-10-15T04:00:00Z The single-stranded molecule sets up a temporary protein factory outside a cell's nucleus and attaches to ribosomes. This mysterious $2 billion biotech is revealing the secrets behind its new drugs and vaccines 2017-02-01T05:00:00Z Double stranded DNA is transcribed into single-stranded RNA, which is then sent to the ribosome where proteins are manufactured. This protein designer aims to revolutionize medicines and materials 2016-07-21T04:00:00Z To make a protein, a cell makes a copy of the corresponding gene, in the form of a single-stranded molecule called RNA. Telling Jewels From Junk in DNA 2016-01-21T05:00:00Z All these jobs, though, use single-stranded versions of RNA, unlike the double-stranded DNA in a cell nucleus. The slopes of enlightenment 2015-10-15T04:00:00Z Unlike DNA viruses, which contain two copies of their genetic information, RNA viruses are single-stranded. How Mutant Viral Swarms Spread Disease 2015-09-14T04:00:00Z To make a protein from DNA, they learned, a cell makes a single-stranded copy of the relevant gene, using a molecule called RNA. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z One seemingly straightforward approach involves using single-stranded DNA molecules. Cellular 'computers' gain a hard drive 2014-11-13T05:00:00Z Soap and water or alcohol-based hand sanitisers readily disrupt the envelope of this single-stranded RNA virus, and decontamination with dilute bleach is effective and readily available even in remote settings. How not to catch Ebola 2014-10-07T04:00:00Z And they contain RNA, a single-stranded molecule similar to DNA. A Tiny Emissary From the Ancient Past 2014-09-25T04:00:00Z He is developing what he calls Cyborg sensors, which include biological and mechanical components – a combination of carbon nanotubes and single-stranded DNA that preferentially bond with one specific chemical compound. Training Dogs to Sniff Out Cancer 2014-09-10T04:00:00Z Next, the researchers add chemicals to 'reverse-transcribe' each short segment of RNA, converting it into circular fragments of single-stranded DNA. Gene Activity Can Now Be Mapped Spatially across Intact Tissue 2014-02-28T22:20:00Z But when single-stranded DNA is floating around in the cell, it is possible to stimulate the bacterium to insert it into its genome, using an enzyme from a virus. Cellular 'computers' gain a hard drive 2014-11-13T05:00:00Z Those primordial organisms relied on a single-stranded variant of DNA, called RNA. Vitamins’ Old, Old Edge 2013-12-09T23:14:35Z The single-stranded fragments are easily broken apart by enzymes in the fluid and by freezing and thawing when samples are shipped and stored. The hidden threat of West Nile virus 2012-09-19T17:21:14.697Z The technique, which they are calling a single-stranded library preparation, involves stripping the genetic material down to individual strands to copy and avoids a purification step, which can lose precious genetic material. New DNA Analysis Shows Ancient Humans Interbred with Denisovans 2012-08-30T23:15:00.443Z RNA molecules are single-stranded copies of the double-helical DNA genes in the cell nucleus. The nature of humanity: What?s a man? 2012-02-02T16:03:12Z However, most bacteria do not readily manufacture a significant number of single-stranded DNAs. Cellular 'computers' gain a hard drive 2014-11-13T05:00:00Z Caliciviruses contain one single piece of single-stranded RNA in a protein capsid with no lipid envelope. Misery-inducing Norovirus Can Survive for Months -- Perhaps Years -- in Drinking Water 2012-01-17T18:45:00.410Z Each sensor consists of a tiny well, inside which sits a fragment of single-stranded DNA linked to a small bead. A $1000 Genome by 2013? 2011-07-20T21:35:09Z Retroviruses carry their genetic material in a single-stranded version of DNA, called RNA. 2010-01-12T05:27:00Z |
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