| 单词 | sickle-cell disease |
| 例句 | These are single-gene disorders such as muscular dystrophy, cystic fibrosis, sickle-cell disease and Tay-Sachs syndrome but they are the exception. Identically Different: Why You Can Change Your Genes by Tim Spector – review 2012-08-08T09:30:03Z For her entire life, the singer and dancer has fought sickle-cell disease, a blood disorder that can be crippling and fatal, and in T-Boz’s case has meant regular hospitalizations, surgeries, drugs and rest. Rock ’n’ Roll, Between the Covers 2017-11-29T05:00:00Z There is no upper age limit, nor are patients excluded because they have suffered too much organ damage from sickle-cell disease, said Dr. David Altshuler, Vertex’s chief scientific officer. Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval 2023-11-16T05:00:00Z In trials, it has been "found to restore healthy haemoglobin production in the majority of participants with sickle-cell disease and transfusion-dependent beta thalassaemia, relieving the symptoms of disease", he said. Casgevy: UK approves gene-editing drug for blood disorders 2023-11-16T05:00:00Z Beyond that, it could play a key role in treating sickle-cell disease and shows promise for the autoimmune disorder multiple sclerosis. Scientists whose work on mRNA paved the way for first COVID-19 vaccines win Nobel Prize 2023-10-02T04:00:00Z Many of the genetic mutations that directly cause a condition, such as those responsible for cystic fibrosis and sickle-cell disease, tend to change the amino acid sequence of the protein they encode. AI Tool Pinpoints Genetic Mutations That Cause Disease 2023-09-21T04:00:00Z For Sharee Turpin, the pain of sickle-cell disease sometimes feels like tiny knives slicing her open. From heart disease to IUDs: How doctors dismiss women’s pain Pain is not the only complication — people with sickle-cell disease also suffer bone and organ damage and strokes. Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval 2023-11-16T05:00:00Z So there are already trials of base editing under way in sickle-cell disease, as well as high cholesterol that runs in families and the blood disorder beta-thalassemia. Base editing: Revolutionary therapy clears girl's incurable cancer 2022-12-10T05:00:00Z We have seen patients with sickle-cell disease admitted because they were in intense pain — yet they also tested positive for the virus. Perspective | Is a patient hospitalized ‘with’ covid or ‘for’ covid? It can be hard to tell. 2022-01-07T05:00:00Z "Now, I have found my true purpose and love spreading awareness of sickle-cell disease," she says. First new treatment for sickle cell in 20 years 2021-10-04T04:00:00Z The bill also would establish protocols for players returning from serious injury as well as guidelines for those athletes who suffer from conditions like sickle-cell disease and asthma. Bill would get college athletes paid for endorsements 2021-03-04T05:00:00Z Ms. Gray, a Walmart associate in Forest, Miss., was diagnosed with sickle-cell disease when she was 3 months old and had a pain crisis. Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval 2023-11-16T05:00:00Z She is now taking part in trials on Crispr treatments of both sickle-cell disease and beta thalassemia conducted in Boston by Crispr Therapeutics in collaboration with Vertex Pharmaceuticals. After the Nobel, what next for Crispr gene-editing therapies? 2021-02-21T05:00:00Z But no one has to prove they have a sickle-cell disease or a kidney condition to sign up for the shot. Editorial Roundup: Pennsylvania 2021-01-27T05:00:00Z Officials added sickle-cell disease to the list and took liver disease off of it in an update on Thursday. CDC: Fewer people dying in COVID-19 surge than March, April 2020-06-25T04:00:00Z For example, children with sickle-cell disease can go on to develop infections, visual problems or stroke8. Map clusters of diseases to tackle multimorbidity 2020-03-23T04:00:00Z Called Casgevy, the treatment is intended to cure sickle-cell disease and a related condition, beta thalassemia. Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval 2023-11-16T05:00:00Z Gene therapy is facing its biggest challenge yet After finally gaining traction as a potential treatment for certain genetic disorders, gene therapy tackles the challenge of sickle-cell disease. Trickster microbes, manels, and Venus 2019-12-16T05:00:00Z Bakatunkanda, who founded a support group for people with sickle-cell disease, is confident that gene therapy, if shown to be effective, will one day reach his country, despite its high cost and daunting complexity. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z As we describe in a News Feature this week, sickle-cell disease is finally catching the attention of funders, governments and pharmaceutical companies. Expensive treatments for genetic disorders are arriving. But who should foot the bill? 2019-12-03T05:00:00Z A potential sickle-cell disease drug being developed by the biotechnology company and Pfizer failed in a key study. Tyson Foods, Allakos rise; Cars.com, ON Semiconductor fall 2019-08-05T04:00:00Z The approach could also provide a safer way to treat people with blood disorders, such as sickle-cell disease, who currently have to undergo a risky procedure before receiving a bone-marrow transplant. Blood stem cells produced in vast quantities in the lab 2019-05-29T04:00:00Z The gene that directs production of CCR5 may be modified with newer gene therapy techniques, similar to treatments developed for hemophilia and sickle-cell disease. An H.I.V. Cure: Answers to 4 Key Questions 2019-03-05T05:00:00Z The elongated, oddly shaped blood cells typical of sickle-cell disease were first noted in 1910 in a young dental student from Grenada, West Indies, named Walter Clement Noel1. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z In 1994, the physician founded Sickle Cell Foundation Nigeria, with a mission to provide support for people with sickle-cell disease — a hereditary blood disorder that affects 20 million individual worldwide. Expensive treatments for genetic disorders are arriving. But who should foot the bill? 2019-12-03T05:00:00Z More recently, in 2017, a researcher at the institute devised a Food and Drug Administration-approved treatment for sickle-cell disease, the first one available for children. South Bay couple donates $70 million to L.A. biomedical institute 2019-02-10T05:00:00Z People with genetic blood disorders such as sickle-cell disease are sometimes treated with a bone-marrow transplant from a donor. Blood stem cells produced in vast quantities in the lab 2019-05-29T04:00:00Z Carmen Duncan, 20, of Charleston, S.C., had her spleen removed when she was 2, a result of complications from sickle-cell disease. These Patients Had Sickle-Cell Disease. Experimental Therapies Might Have Cured Them. 2019-01-27T05:00:00Z Seventy years after Pauling’s discovery, sickle-cell disease is still underdiagnosed in many African countries, says haematologist Olu Akinyanju, the founder and first chairperson of the Sickle Cell Foundation Nigeria in Lagos. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Experts have long maintained that advances in treatment have been limited partly because sickle-cell disease is concentrated in less affluent minority communities. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z Red blood cells are supposed to be shaped like concave discs, but in people with sickle-cell disease, a mutation in a single gene collapses them into a crescent shape. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z As with children in wealthy countries, taking the drug daily also made it far less likely they would die or need a blood transfusion because of their sickle-cell disease. ‘From Nothing to Gangbusters’: A Treatment for Sickle-Cell Disease Proves Effective in Africa 2018-12-01T05:00:00Z An estimated 100,000 people in the United States have sickle-cell disease. These Patients Had Sickle-Cell Disease. Experimental Therapies Might Have Cured Them. 2019-01-27T05:00:00Z Against that backdrop, some felt that it was premature to apply gene therapy to sickle-cell disease, says haematologist David Williams at Boston Children’s Hospital in Massachusetts. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Scientists have long known what causes sickle-cell disease and its devastating effects: a single mutation in one errant gene. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z Gene therapy might offer a cure for sickle-cell disease, and clinical trials are already under way. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z There, he did routine tasks and led a side project, with Platt’s guidance, on sickle-cell disease. How working as a research technician can bolster your scientific career 2018-08-20T04:00:00Z In the 1980s, when researchers first began thinking of gene therapy to correct genetic disorders, sickle-cell disease was at the top of the list. These Patients Had Sickle-Cell Disease. Experimental Therapies Might Have Cured Them. 2019-01-27T05:00:00Z This means that gene therapy would probably be used only in those with the most serious forms of sickle-cell disease. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Because of his sickle-cell disease, he had suffered four strokes by age 18. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z The only current cure for sickle-cell disease is a bone-marrow transplant from a matched healthy donor. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z Researchers at Stanford School of Medicine are also moving a Crispr treatment for sickle-cell disease to clinical trials. Forget Juicero, here are the tech gadgets we can actually get excited about in 2018 2017-12-28T05:00:00Z We don't hear of successful screening programmes for newborns, or emerging gene or cancer therapies such as those for spinal muscular atrophy or Duchenne muscular dystrophy, sickle-cell disease or leukaemia. Bioethics: Justice in genomics 2017-11-14T05:00:00Z Ageing brings some benefits to people with sickle-cell disease. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Among the many problems that plagued gene therapy research, there were ones specific to sickle-cell disease. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z The clinical trials will demonstrate whether gene therapy is effective at curing sickle-cell disease. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z They also used ABE to install a different genetic mutation that compensates for the DNA defect that causes sickle-cell disease. New Gene-Editing 'Pencil' Erases Disease-Causing Errors 2017-10-25T04:00:00Z “We know sickle-cell disease is caused by this gene, by this cell, and all we're doing is hydration and pain control,” Porteus says. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z But that is too dangerous to use in people with sickle-cell disease because it raises the risk of pain crises. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z In sickle-cell disease, blood cells stuffed with hemoglobin are distorted into sickle shapes. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z In the long term, an expensive cure for sickle-cell disease would probably be cheaper than — and much more preferable to — dealing with 30–40 years of the disease’s chronic, long-term effects. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z People suffering from sickle-cell disease, for instance, have just a single mutated “letter” in the DNA coding for their hemoglobin . Opinion | New gene-editing tool could cure disease. Or customize kids. Or aid bioterrorism. 2017-06-28T04:00:00Z Meeting that patient inspired Porteus to go into haematology, and to work on sickle-cell disease. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z And because diseased red blood cells die faster than healthy ones, the stem cells in a person with sickle-cell disease must work harder to produce new blood cells. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z All four produced enough normal hemoglobin that they no longer had symptoms of sickle-cell disease. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z Current trials involve small numbers of people with sickle-cell disease, but if the treatments work, future trials will require many more participants. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z Treatments are also steadily moving ahead for rarer single-mutation blood illnesses, such as thalassaemia and sickle-cell disease, says Gregory. Gene therapy: Industrial strength : Nature : Nature Research 2016-09-06T04:00:00Z The idea is that a single, albeit complex, treatment could spare children with sickle-cell disease a lifetime of missed days of school and work, hospital visits and organ damage. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z “It’s an enormous ethical issue,” says Krishnamurti, who counsels people with sickle-cell disease each week from his hospital in Atlanta. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Carmen Duncan, 20, of Charleston, South Carolina, had her spleen removed when she was 2, a result of complications from sickle-cell disease. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z “The hallmark of sickle-cell disease is pain, and it’s excruciating pain. It’s like putting a tourniquet on and depriving a limb of oxygen,” says Walters. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z They are developing potential treatments for muscular dystrophy, sickle-cell disease and cancer. Scientists debate ethics of human gene editing at international summit 2015-12-01T05:00:00Z It turns out that people with sickle-cell disease who are not badly affected by symptoms have genetic variations that enable them to produce fetal haemoglobin into adulthood. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Malik trained as a doctor in India, where she saw many people with sickle-cell disease and related conditions. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z Today, doctors say, she no longer has signs of sickle-cell disease. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z The fate of people with sickle-cell disease is largely determined before they are born. Sickle-cell disease : Nature : Nature Publishing Group 2014-11-11T05:00:00Z One possible hypothesis was that these traditional descriptions were based on a highly selected, symptomatic group of patients available to the doctors writing on sickle-cell disease. Q&A: Healthy progress : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Red blood cells produced from the edited haematopoietic stem cells of patients with sickle-cell disease produced 25% more fetal haemoglobin than unedited cells, and the edited cells successfully engrafted in mice. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z People with sickle-cell disease experience bursts of debilitating agony from birth. Neurobiology: Life beyond the pain : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Tantalizing science In the 1980s, when researchers first began thinking of gene therapy to correct genetic disorders, sickle-cell disease was at the top of the list. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z To address sickle-cell disease in low-income countries requires a number of feasible steps. Perspective: We need a global solution : Nature : Nature Publishing Group 2014-11-11T05:00:00Z How big is the current burden of sickle-cell disease? Q&A: Healthy progress : Nature : Nature Publishing Group 2014-11-11T05:00:00Z To get a more realistic assessment of the technique and its potential in people, Tisdale is planning to test gene editing for sickle-cell disease in primates. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z As children with sickle-cell disease grow older, the pain worsens. Neurobiology: Life beyond the pain : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Some researchers are trying to block the gene that turns off fetal hemoglobin and turns on adult hemoglobin, allowing patients with sickle-cell disease to produce fetal hemoglobin instead. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z We need public-awareness campaigns to combat stigma and mis-understandings about sickle-cell disease, and to provide opportunities for genetic counselling and initiatives that promote disease avoidance. Perspective: We need a global solution : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Diarrhoea, infections and malaria may cause more deaths than sickle-cell disease, but as we begin to control these and other conditions, sickle cell is going to emerge as an increasingly larger problem. Q&A: Healthy progress : Nature : Nature Publishing Group 2014-11-11T05:00:00Z His work on bone-marrow transplants for adults with sickle-cell disease has helped to establish that at least 20% of edited cells must become established in the bone marrow. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z At first glance, a child with sickle-cell disease may appear healthy. Neurobiology: Life beyond the pain : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Experts have long maintained that advances in treatment have been limited partly because sickle-cell disease is concentrated in less affluent minority communities. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z The disparity in outcomes for children with sickle-cell disease in developed and developing countries is an injustice, says Isaac Odame. Perspective: We need a global solution : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Correcting the genetic error in sickle-cell disease might be as simple as amending text. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Even if the clinical trials succeed and patients are cured, gene-editing-based therapy for sickle-cell disease is still likely to be expensive. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Stem cells harvested here can help patients with sickle-cell disease and leukaemia. Stem cells: Creating a cure-all : Nature : Nature Publishing Group 2014-11-11T05:00:00Z At the moment, the only remedy for sickle-cell disease is a dangerous and expensive bone marrow transplant, an option rarely used. Sickle-cell patients dreamed of a cure; enter gene therapy 2019-01-26T05:00:00Z So the burden of sickle-cell disease will continue to rise, placing an increasing strain on limited health-care resources. Perspective: We need a global solution : Nature : Nature Publishing Group 2014-11-11T05:00:00Z A researcher corrects a mutation in the β-globin gene that causes sickle-cell disease. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z The pain, caused by a blocked blood vessel, is common in people with a blood disorder called sickle-cell disease. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Like all patients with sickle-cell disease, Stephanie Alvarado-Ross had to cope with excruciating pain, anxiety and stress, and faced the likelihood of an early death. Stem cells: Creating a cure-all : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Children born with sickle-cell disease in high-income countries are now expected to live to adulthood, an improvement in life expectancy that is a major medical advance. Perspective: Thinking beyond survival : Nature : Nature Publishing Group 2014-11-11T05:00:00Z This is only compounded by the lack of public understanding of sickle-cell disease, which perpetuates social stigma and myths about disease causation and results in few people seeking appropriate treatment. Perspective: We need a global solution : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Gang Bao, a biomedical engineer at the Georgia Institute of Technology in Atlanta, is developing gene-editing strategies for sickle-cell disease and is paying particular attention to the challenge of limiting off-target effects. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z To make it work for sickle-cell disease, researchers must grapple with two relatively unproven technologies — not only gene editing, but also stem-cell therapy. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Stem-cell transplantation can cure sickle-cell disease, but so far this has been limited to a lucky few. Stem cells: Creating a cure-all : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Both biological and non-biological risk factors must be considered collectively if we expect to not only extend the lives of children born with sickle-cell disease, but also improve their quality of life. Perspective: Thinking beyond survival : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Ironically, improved medical treatment leading to longer life expectancy is contributing to the increased prevalence of sickle-cell disease. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z It was quickly adopted for use in sickle-cell disease. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z In November 2016, the team successfully used the viral approach to edit haematopoietic stem cells from patients with sickle-cell disease in the lab. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z A team led by Alan Flake, director of the Children's Center for Fetal Research at the Children's Hospital of Philadelphia, Pennsylvania, has successfully treated sickle-cell disease in utero in mice and dogs4. Stem cells: Creating a cure-all : Nature : Nature Publishing Group 2014-11-11T05:00:00Z The only therapy currently approved to treat sickle-cell disease, hydroxycarbamide, acts in a different way from the drugs being developed. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z The US Department of Health and Human Service's National Heart, Lung and Blood Institute suggests that sickle-cell disease affects about 1 in 500 African American babies, a number about ten times greater the general population. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z One of the challenges in treating sickle-cell disease with gene therapy is that it is necessary to extract bone marrow to retrieve haematopoietic stem cells. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z In the process of developing various gene-based strategies to treat sickle-cell disease, researchers are learning a lot about the basic biology of the disorders — and the needs of patients are getting long-overdue attention. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z But even if it remains at 40%, he says, “the only major risk of failure is that the child will still be born with sickle-cell disease, which would have happened anyway.” Stem cells: Creating a cure-all : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Only one drug is available to treat sickle-cell disease, but a wave of investment and industry attention is set to turn the tide. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z It is no coincidence that sickle-cell disease and malaria share similar global distributions. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z Doctors will first harvest bone marrow from the hip bones of patients with sickle-cell disease and then extract haematopoietic stem cells from the marrow. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z They hope to cure sickle-cell disease while patients are still children, by editing the haemoglobin genes in stem cells taken from the children's blood-producing bone marrow, which can then be transplanted back. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Hospitals in Pennsylvania are already required to screen for phenylketonuria, maple syrup urine disease, sickle-cell disease, galactosemia, congenital adrenal hyperplasia and primary congenital hypothyroidism. Corbett to sign bill expanding newborn screenings 2014-10-09T04:00:00Z In addition, children with certain other conditions -- such as heart problems, chronic lung disease and sickle-cell disease -- are part of the "key group" at risk of complications from the flu and other viruses, Maniaci said. When Colds, Flu Lead to Complications in Kids 2014-08-04T04:00:00Z About 70% of global cases of sickle-cell disease are in Africa. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z In sickle-cell disease, the only cells that need their DNA edited are blood stem cells — also known as haematopoietic stem cells — which are found in bone marrow. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z The lack of a cure for sickle-cell disease is especially frustrating for haematologists, because the condition is common and has been well understood for decades. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Broderick said that may be due to dehydration among people with sickle-cell disease. Sickle cell disease accounts for many priapism cases 2013-04-25T21:48:43Z A debilitating genetic disorder, sickle-cell disease causes blood cells to be shaped like sickles, or crescents, and to be rigid, not pliable. ‘Half-Match’ Bone Marrow Transplants Cure Sickle Cell in Trial 2012-11-12T21:44:33Z But they also include sickle-cell disease, a blood disorder that is the biggest non-communicable killer of Africa’s children. Chronic diseases in developing countries: Growing pains 2011-09-22T06:17:45Z The doctor, who calls himself a “physician musician,” went on to produce songs about sickle-cell disease, diabetes, allergies, depression, teenage pregnancy and domestic violence. A Physician's a Musician, and Safety Is His Mission 2010-07-19T19:52:00Z About 10% of people with sickle-cell disease are able to get a bone-marrow transplant from a healthy family member with a matching tissue type. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z Authors of the law say they meant to ban all forms of discrimination against children with pre-existing conditions such as asthma, diabetes, birth defects, orthopedic problems, leukemia, cystic fibrosis and sickle-cell disease. Coverage for all children? Check new health-care law's fine print 2010-03-29T07:16:00Z Red blood cells in sickle-cell disease have a characteristic elongated shape. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z |
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