英语词汇“secretase”造句子简单的方法、技巧、例句及翻译-英语例句辞典

One, secretase inhibitors, are traditional small-molecule drugs that target an enzyme that produces beta amyloid from a larger protein. Promising Alzheimer’s therapy and related drugs shrink brains 2023-03-28T04:00:00Z

Both hallmarks of Alzheimer’s disease were reduced when the secretases that chop up APP were inhibited — a strategy also being pursued in clinical trials. The search for better animal models of Alzheimer’s disease 2018-07-24T04:00:00Z

Both drugs target types of an enzyme called secretase. Lilly stops mid-stage Alzheimer's drug study 2013-06-13T22:10:11Z

It also has a drug in Phase II testing from a promising class called beta secretase, or BACE, inhibitors. Eli Lilly CEO says company keeping animal health business 2013-02-11T21:33:33Z

Meanwhile, other Alzheimer's drugs will be tested beginning next year as part of her project, including a promising class of drugs called beta secretase inhibitors. Lilly drug chosen for U.S.-sponsored Alzheimer's trial 2013-01-19T01:59:59Z

The authors also reported that the antiamyloid antibodies—but not the secretase inhibitors—led to an increase in the size of brain ventricles, indicating they were filling with extra fluid. Promising Alzheimer’s therapy and related drugs shrink brains 2023-03-28T04:00:00Z

Meanwhile, she said other Alzheimer's drugs will be tested beginning next year as part of her project, including a promising class of drugs called beta secretase inhibitors. Lilly drug chosen for U.S.-sponsored Alzheimer's trial 2013-01-18T19:43:16Z

Lilly, along with Merck & Co Inc and others, is developing another class of drugs that block amyloid through a different route - by inhibiting production of an enzyme called beta secretase. Lilly Alzheimer's drug gets second chance, plans new trial 2012-12-12T15:26:53Z

Excitement about the class of drugs intensified in July, when researchers in Iceland identified a mutation in a gene that slows the body's production of beta secretase, Lundberg said. Lilly likens Alzheimer's race to 1920s insulin quest 2012-12-11T20:47:54Z

But targeting these enzymes has proven tricky, partly because -secretase is not specific to APP but also cleaves other proteins — including the vital protein Notch. Drugs: A tangled web of targets 2011-07-13T17:20:55.130Z

Most of the new drugs target an enzyme, gamma secretase, that snips a big protein to produce beta amyloid. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z

Other companies are testing different drugs that disable that enzyme, gamma secretase. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z

Companies are developing so-called selective gamma secretase inhibitors, Dr. Paul said, which only block the production of a beta 42. News Analysis: Failure of Lilly Alzheimer?s Drug Casts Doubt on Anti-Amyloid Efforts 2010-08-18T16:50:00Z

Lilly’s drug was intended to reduce production of so-called amyloid beta plaques in the brain by inhibiting the activity of an enzyme called gamma secretase. Lilly Stops 2 Alzheimer?s Drug Trials 2010-08-18T01:09:00Z

All eyes, however, are trained on a passive immune therapy that leaves both secretase enzymes alone and goes after amyloid-β directly. Drugs: A tangled web of targets 2011-07-13T17:20:55.130Z

Many scientists think that was what went wrong with the Eli Lilly drug, which, researchers say, took a sledgehammer to gamma secretase, stopping all of its functions. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z

They say gamma secretase inhibitors now under development are much more selective and may be much safer. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z

Lilly’s drug was designed to reduce the body’s production of the plaques by inhibiting the activity of an enzyme, called gamma secretase, that is believed to play an important role in formation of the plaque. Lilly Halts Alzheimer's Drug Trial 2010-08-17T15:36:00Z

“Gamma secretase belongs to a family of proteins called proteases,” he explained. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z

It meant that Dr. Greengard was correct — the newly discovered protein, when blocked, does not seem to interfere with other crucial functions of gamma secretase. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z

The system he discovered — the gamma secretase activating protein — made sense, Dr. Greengard said. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z

The antibody therapies are distinctly different from the gamma secretase inhibitors. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z

单词	secretase
例句	secretase One, secretase inhibitors, are traditional small-molecule drugs that target an enzyme that produces beta amyloid from a larger protein. Promising Alzheimer’s therapy and related drugs shrink brains 2023-03-28T04:00:00Z Both hallmarks of Alzheimer’s disease were reduced when the secretases that chop up APP were inhibited — a strategy also being pursued in clinical trials. The search for better animal models of Alzheimer’s disease 2018-07-24T04:00:00Z Both drugs target types of an enzyme called secretase. Lilly stops mid-stage Alzheimer's drug study 2013-06-13T22:10:11Z It also has a drug in Phase II testing from a promising class called beta secretase, or BACE, inhibitors. Eli Lilly CEO says company keeping animal health business 2013-02-11T21:33:33Z Meanwhile, other Alzheimer's drugs will be tested beginning next year as part of her project, including a promising class of drugs called beta secretase inhibitors. Lilly drug chosen for U.S.-sponsored Alzheimer's trial 2013-01-19T01:59:59Z The authors also reported that the antiamyloid antibodies—but not the secretase inhibitors—led to an increase in the size of brain ventricles, indicating they were filling with extra fluid. Promising Alzheimer’s therapy and related drugs shrink brains 2023-03-28T04:00:00Z Meanwhile, she said other Alzheimer's drugs will be tested beginning next year as part of her project, including a promising class of drugs called beta secretase inhibitors. Lilly drug chosen for U.S.-sponsored Alzheimer's trial 2013-01-18T19:43:16Z Lilly, along with Merck & Co Inc and others, is developing another class of drugs that block amyloid through a different route - by inhibiting production of an enzyme called beta secretase. Lilly Alzheimer's drug gets second chance, plans new trial 2012-12-12T15:26:53Z Excitement about the class of drugs intensified in July, when researchers in Iceland identified a mutation in a gene that slows the body's production of beta secretase, Lundberg said. Lilly likens Alzheimer's race to 1920s insulin quest 2012-12-11T20:47:54Z But targeting these enzymes has proven tricky, partly because -secretase is not specific to APP but also cleaves other proteins — including the vital protein Notch. Drugs: A tangled web of targets 2011-07-13T17:20:55.130Z Most of the new drugs target an enzyme, gamma secretase, that snips a big protein to produce beta amyloid. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z Other companies are testing different drugs that disable that enzyme, gamma secretase. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z Companies are developing so-called selective gamma secretase inhibitors, Dr. Paul said, which only block the production of a beta 42. News Analysis: Failure of Lilly Alzheimer?s Drug Casts Doubt on Anti-Amyloid Efforts 2010-08-18T16:50:00Z Lilly’s drug was intended to reduce production of so-called amyloid beta plaques in the brain by inhibiting the activity of an enzyme called gamma secretase. Lilly Stops 2 Alzheimer?s Drug Trials 2010-08-18T01:09:00Z All eyes, however, are trained on a passive immune therapy that leaves both secretase enzymes alone and goes after amyloid-β directly. Drugs: A tangled web of targets 2011-07-13T17:20:55.130Z Many scientists think that was what went wrong with the Eli Lilly drug, which, researchers say, took a sledgehammer to gamma secretase, stopping all of its functions. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z They say gamma secretase inhibitors now under development are much more selective and may be much safer. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z Lilly’s drug was designed to reduce the body’s production of the plaques by inhibiting the activity of an enzyme, called gamma secretase, that is believed to play an important role in formation of the plaque. Lilly Halts Alzheimer's Drug Trial 2010-08-17T15:36:00Z “Gamma secretase belongs to a family of proteins called proteases,” he explained. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z It meant that Dr. Greengard was correct — the newly discovered protein, when blocked, does not seem to interfere with other crucial functions of gamma secretase. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z The system he discovered — the gamma secretase activating protein — made sense, Dr. Greengard said. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z The antibody therapies are distinctly different from the gamma secretase inhibitors. What to Tell the Patients After a Trial Goes Awry 2010-08-23T19:39:00Z
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