| 单词 | sarcomere |
| 例句 | At the core of this vital organ, intricate processes occur when it contracts, where thick and thin protein-filaments interact within the sarcomere, the fundamental building block of both skeletal and heart muscle cells. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z The combined activity of many binding sites and repeated movements within the sarcomere causes it to contract. Concepts of Biology 2013-04-25T00:00:00Z One sarcomere is the space between two consecutive Z discs and contains one entire A band and two halves of an I band, one on either side of the A band. Biology for AP Courses 2022-06-09T00:00:00Z A sarcomere is the smallest contractile portion of a muscle. Anatomy and Physiology 2013-06-19T00:00:00Z When a sarcomere shortens, some regions shorten whereas others stay the same length. Biology for AP Courses 2022-06-09T00:00:00Z Skeletal and heart muscles contract upon the interaction of two types of parallel protein filaments in the sarcomere: thin and thick. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z The thick and thin filaments alternate with each other in a structure called a sarcomere. Concepts of Biology 2013-04-25T00:00:00Z Thin filaments are pulled by the thick filaments toward the center of the sarcomere until the Z discs approach the thick filaments. Biology for AP Courses 2022-06-09T00:00:00Z The length of a sarcomere is optimal when the zone of overlap between thin and thick filaments is greatest. Anatomy and Physiology 2013-06-19T00:00:00Z A sarcomere is defined as the distance between two consecutive Z discs or Z lines; when a muscle contracts, the distance between the Z discs is reduced. Biology for AP Courses 2022-06-09T00:00:00Z The sarcomere is subdivided in several regions, called zones and bands, in which these filaments are arranged in different ways. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z The sarcomere is the unit of contraction in a muscle cell. Concepts of Biology 2013-04-25T00:00:00Z If a sarcomere at rest is stretched past an ideal resting length, thick and thin filaments do not overlap to the greatest degree, and fewer cross-bridges can form. Biology for AP Courses 2022-06-09T00:00:00Z Figure 10.10 The Sliding Filament Model of Muscle Contraction When a sarcomere contracts, the Z lines move closer together, and the I band becomes smaller. Anatomy and Physiology 2013-06-19T00:00:00Z As the actin is pulled toward the M line, the sarcomere shortens and the muscle contracts. Biology for AP Courses 2022-06-09T00:00:00Z The scientists suspect, that this allows the thick filament to sense and process numerous muscle-regulating signals and thus to regulate the strength of muscle contraction depending on the sarcomere region. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z For a muscle cell to contract, the sarcomere must shorten. Concepts of Biology 2013-04-25T00:00:00Z As a sarcomere is shortened, the zone of overlap is reduced as the thin filaments reach the H zone, which is composed of myosin tails. Biology for AP Courses 2022-06-09T00:00:00Z Isometric contractions involve sarcomere shortening and increasing muscle tension, but do not move a load, as the force produced cannot overcome the resistance provided by the load. Anatomy and Physiology 2013-06-19T00:00:00Z The ideal length of a sarcomere during production of maximal tension occurs when thick and thin filaments overlap to the greatest degree. Biology for AP Courses 2022-06-09T00:00:00Z Titin chains intertwine with myosin, acting as a scaffold for its assembly and probably orchestrating a length-depending activation of the sarcomere. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z If the sarcomere is shortened even more, thin filaments begin to overlap with each other—reducing cross-bridge formation even further, and producing even less tension. Biology for AP Courses 2022-06-09T00:00:00Z Figure 29.35 A sarcomere is the region from one Z line to the next Z line. Biology for AP Courses 2022-06-09T00:00:00Z The cross-bridges can only form where thin and thick filaments already overlap, so that the length of the sarcomere has a direct influence on the force generated when the sarcomere shortens. Anatomy and Physiology 2013-06-19T00:00:00Z Conversely, if the sarcomere is stretched to the point at which thick and thin filaments do not overlap at all, no cross-bridges are formed and no tension is produced. Biology for AP Courses 2022-06-09T00:00:00Z In recent years, Raunser's group successfully applied the customized workflow, resulting in two recent groundbreaking publications: They produced the first high-resolution images of the sarcomere and of a so far nebulous muscle protein called nebulin. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z The thin filaments are then pulled by the myosin heads to slide past the thick filaments toward the center of the sarcomere. Anatomy and Physiology 2013-06-19T00:00:00Z Instead, they slide by one another, causing the sarcomere to shorten while the filaments remain the same length. Biology for AP Courses 2022-06-09T00:00:00Z The sarcomere is the functional unit of the muscle fiber. Anatomy and Physiology 2013-06-19T00:00:00Z If the muscle is stretched to the point where thick and thin filaments do not overlap at all, no cross-bridges can be formed, and no tension is produced in that sarcomere. Anatomy and Physiology 2013-06-19T00:00:00Z In their current study the scientists produced the first high-resolution image of the cardiac thick filament spanning across several regions in the sarcomere. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z With increased ventricular filling, the ventricular muscle is increasingly stretched and the sarcomere length increases. Anatomy and Physiology 2013-06-19T00:00:00Z The sliding filament theory of muscle contraction was developed to fit the differences observed in the named bands on the sarcomere at different degrees of muscle contraction and relaxation. Biology for AP Courses 2022-06-09T00:00:00Z The sarcomere itself is bundled within the myofibril that runs the entire length of the muscle fiber and attaches to the sarcolemma at its end. Anatomy and Physiology 2013-06-19T00:00:00Z |
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