| 单词 | ribavirin |
| 例句 | Before powerful hepatitis C drugs arrived in recent years, doctors frequently used a pill known as ribavirin as part of combination therapy to treat hepatitis C patients. Merck’s COVID pill might pose risks for pregnant women 2021-12-13T05:00:00Z Orders for antibiotics like azithromycin and antiviral medicines like ribavirin nearly tripled. Essential Drug Supplies for Virus Patients Are Running Low 2020-04-02T04:00:00Z The patients were subsequently treated with certain antiviral and antibiotic medications, which NPR identified as ribavirin and benzylpenicillin sodium, respectively. New tick-borne disease discovered in China infecting dozens, researchers claim 2019-06-05T04:00:00Z For now, the only treatment is a nonspecific antiviral drug, ribavirin. Health workers scramble to contain deadly rat-borne fever in Nigeria 2018-03-12T04:00:00Z There is no vaccine and no definitive cure, although an antiviral drug, ribavirin, can be helpful if given early. Lassa Fever Erupts in Nigeria 2018-02-16T05:00:00Z The drug is designed to be used in combination with ribavirin, an older antiviral drug. FDA approves first pill to treat all forms of hepatitis C 2016-06-28T04:00:00Z Committed to repairing the damage done by the schistosomiasis campaign, the health ministry in 2007 developed an ambitious national hepatitis treatment plan using two old drugs: interferon and ribavirin. Public Health Experiment Brings Hepatitis Cures to Egypt’s Poor 2015-12-15T05:00:00Z The Technivie/ribavirin combination was evaluated in a clinical study involving some 135 people. Technivie Approved for Hepatitis C 2015-07-24T04:00:00Z I chose treatment, specifically three self-administered interferon injections each week and two ribavirin pills each day, for a year. I had hepatitis C and didn’t know it. You may have it, too. More than 65 percent of these patients received the new drug without other currently used drugs such as ribavirin and pegylated-interferon alfa. One In 12 Hepatitis C Patients Not Adhering To $1,000/Day Pill 2014-09-17T04:00:00Z Moreover, the continued need for interferon and ribavirin, with their attendant side effects, was a huge drawback. We Now Have the Cure for Hepatitis C, but Can We Afford It? 2014-09-04T04:00:00Z The broad-spectrum antiviral drug, ribavirin, is not effective against viruses like Ebola. Do We Have Any Drugs To Treat Ebola? 2014-07-30T04:00:00Z Those are taken with ribavirin and interferon, work by blocking an enzyme needed for copying the virus, and boost the cure rate to about 75 percent. Merck to pay $3.85B for hepatitis C drug developer 2014-06-09T04:00:00Z I would still inject interferon and take ribavirin, but I would add a daily dose of Solvadi. I had hepatitis C and didn’t know it. You may have it, too. Until now the standard of treatment for the disease consisted of a combination of PEGylated interferon and ribavirin, a stop-gag measure that results in debilitating flu-like symptoms acutely affecting quality of life. (Don't) Mind the Gap: Manufacutring Costs and Drug Prices 2014-04-24T17:19:37Z Standard treatment for hepatitis C has long been a synthetic, injectable version of interferon, one of the immune system's most powerful proteins, plus the antiviral drug ribavirin. We Now Have the Cure for Hepatitis C, but Can We Afford It? 2014-09-04T04:00:00Z Until recently, physicians relied on two wide-spectrum antiviral medications — interferon and ribavirin — that required precise dosing over periods as long as 48 weeks. New drugs cure hepatitis C, research finds 2014-04-13T02:02:50Z More patients in the ribavirin group suffered side effects such as fatigue, headache and nausea. Doctors welcome hepatitis C drug rivals, Gilead still leads 2014-04-11T05:04:35Z The study also included results of patients treated with the two Merck drugs plus the older drug ribavirin for both 12 weeks and eight weeks. Merck hepatitis C drugs shine in easier to treat patients: study 2014-04-10T05:17:52Z Until late last year, the standard treatment for hepatitis C infection was a challenging 48-week regimen of weekly injections with interferon along with one or two oral antiviral drugs, ribavirin and a protease inhibitor. Well: Progress Against Hepatitis C, a Sneaky Virus 2014-02-24T05:01:20Z During sofosbuvir's development, they had studied other drugs that inhibited different viral proteins and that might eliminate the need for continued use of interferon and ribavirin. We Now Have the Cure for Hepatitis C, but Can We Afford It? 2014-09-04T04:00:00Z AbbVie's treatment, known as 3D regimen, combines three drugs along with ribavirin. AbbVie says 96 percent patients in oral hepatitis C study show improvement 2013-12-10T13:34:51Z For genotype 1, which accounts for more than 70 percent of American cases, Sovaldi is supposed to be used with injected interferon and ribavirin. F.D.A. Approves Pill to Treat Hepatitis C 2013-12-07T01:41:01Z The other two arms - one testing 50 mg of MK-8742 and one using 20 mg - did include ribavirin given twice a day. High cure rates seen with Merck oral hepatitis drugs: study 2013-11-02T13:37:18Z The panel voted 15 to 0 in favor of approval of the drug in patients with two variants of the liver-damaging disease - genotype 2 and genotype 3 - in combination with an existing treatment, ribavirin. FDA panel unanimously backs Gilead's hepatitis C drug sofosbuvir 2013-10-25T18:55:01Z It has first sought FDA approval to use sofosbuvir along with ribavirin as an all-oral therapy for genotype 2 and 3 infections, or about 28 percent of the U.S. hepatitis C patient population. Preview - New wave of oral hepatitis C drugs near U.S. approval 2013-10-23T16:38:38Z Current treatments introduced in 2011 must still be taken with ribavirin and the injected drug interferon, which causes miserable flu-like symptoms and leads many patients to delay or discontinue treatment. Gilead combo hepatitis C pill effective in small trial 2013-05-02T16:18:53Z For genotypes 2 and 3, which together account for about 20 to 25 percent of cases in the United States, Sovaldi’s label recommends the drug be used with ribavirin. F.D.A. Approves Pill to Treat Hepatitis C 2013-12-07T01:41:01Z It is also looking at a regimen of only 8 weeks in previously untreated patients that would include ribavirin. High cure rates seen with Merck oral hepatitis drugs: study 2013-11-02T13:37:18Z Current treatment regimens for the disease still include the older, difficult-to-tolerate drugs interferon and ribavirin and are typically taken for either 24 weeks or 48 weeks. Bristol-Myers oral hepatitis C regimen looks competitive: study 2013-04-23T10:04:53Z The standard treatment has long been a combination of interferon, given by injection, and ribavirin, a pill. Preview - New wave of oral hepatitis C drugs near U.S. approval 2013-10-23T16:38:38Z That may suggest that 12 weeks of treatment will be necessary if ribavirin is not part of the regimen. Gilead combo hepatitis C pill effective in small trial 2013-05-02T16:18:53Z Those were given along with the generic antiviral medicine, ribavirin. AbbVie hepatitis C drugs knock out virus at eight weeks 2013-04-23T10:05:57Z The treatments tested with and without the older drug ribavirin led to cure rates of 96 percent to 100 percent, according to interim data from a small midstage clinical trial. High cure rates seen with Merck oral hepatitis drugs: study 2013-11-02T13:37:18Z The study tested Gilead's sofosbuvir, in combination with a standard drug for the infection, ribavirin, in patients with genotype 2 or 3 of the virus who did not respond to prior treatments. Gilead's hep C drug meets main goal of fourth late-stage study 2013-02-19T15:44:57Z But in the new study, the extract was no better than a drug-free placebo at easing signs of the disease among people who hadn't responded to traditional remedies, such as peginterferon and ribavirin. Milk thistle extract doesn't ease liver infection 2012-07-17T20:06:36Z It will evaluate the combination tablet for eight weeks of treatment, with and without ribavirin, as well as for 12 weeks without ribavirin. Gilead combo hepatitis C pill effective in small trial 2013-05-02T16:18:53Z The drug was tested in combination with ribavirin, a medication currently used in treating the disease. Gilead Rises on Hepatitis C Trial Results: San Francisco Mover 2012-02-03T21:32:02Z The drug was tested in combination with ribavirin, which is currently used in treating the disease in patients with hepatitis C genotypes 2 and 3. Pharmasset Poised to Pay 20% With Gilead Deal Closing: Real M&A 2011-12-05T23:59:49Z In trials, telaprevir and boceprevir elicited response rates that were 20 to 30 percent higher than those seen with the older regimen—pegylated interferon plus ribavirin—by itself, an encouraging result. Going Viral: New Hepatitis C Drugs Owe Their Success to HIV 2011-08-05T12:15:00.933Z Transgene recently started a phase II study to further assess TG4040's efficacy in combination with the standard antiviral regimen of interferon-α plus ribavirin. Vaccines: A moving target 2011-06-13T13:20:41.413Z The one patient who relapsed was from a group that took the combo tablet but not ribavirin, the company said. Gilead combo hepatitis C pill effective in small trial 2013-05-02T16:18:53Z Taking only 80% of the prescribed interferon and ribavirin dosages for 80 of the projected duration of treatment is sufficient to achieve optimal response rates. Perspective: Recognizing resistance 2011-06-13T13:20:36.973Z The continued need for interferon- and ribavirin is disappointing because the new agents worsen the problematic side effects of standard therapy, especially rashes for telaprevir and anaemia for both telaprevir and boceprevir. Perspective: Miles to go before we sleep 2011-06-13T13:20:34.157Z These problems are in addition to those caused by interferon-α and ribavirin, meaning that nearly every patient in the clinical trials suffered from at least one side effect. Therapeutics: New drugs hit the target 2011-06-13T13:20:32.767Z The standard treatment for HCV infection is two daily doses of ribavirin, a nonspecific antiviral agent, combined with a weekly injection of interferon-α, which activates the immune system and impedes viral replication. Introduction: A smouldering public-health crisis 2011-06-13T13:20:31.180Z Either of the drugs must be used as part of the underlying treatment with Victrelis, along with ribavirin. Merck, Roche forge hepatitis C sales deal 2011-05-17T23:27:31Z Already, there is an expectation that Merck will be able to gain pricing and marketing advantages because it sells the current standard of care drugs, ribavirin and pegylated interferon. Merck Wins Victory Over Skeptics With Hepatitis C Approval 2011-05-14T13:20:08Z Ten patients got the two drugs together with interferon and generic ribavirin. Bristol-Myers Interferon-Free Combo Cured Hepatitis Patients 2011-04-02T20:48:43Z Without interferon-α and ribavirin, the virus was expected to rebound after treatment, but this occurred in only one case. Therapeutics: New drugs hit the target 2011-06-13T13:20:32.767Z They will supplement, but not replace, the standard interferon plus ribavirin therapy. Introduction: A smouldering public-health crisis 2011-06-13T13:20:31.180Z Even with interferon and ribavirin, resistance "remains a concern," he says. New Drugs for Hepatitis C On the Horizon 2011-03-30T21:45:00.247Z The HCV regime contains two nonspecific antiviral drugs called interferon and ribavirin. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z The existing treatment, using alpha interferon and ribavirin, takes nearly a year, causes severe side effects and succeeds in eradicating the virus only about half the time. Promising Results Reported for Cholesterol and Hepatitis C Drugs 2010-08-05T00:26:00Z In the current regimen, interferon-α boosts the patient's immune system, and ribavirin is a general inhibitor of virus replication. Therapeutics: New drugs hit the target 2011-06-13T13:20:32.767Z The existing treatment — with alpha interferon and ribavirin – can take nearly a year, causes severe side effects and succeeds in eradicating the hepatitis C virus only about half the time. Hepatitis, Cholesterol Drugs Show Promise 2010-08-04T15:46:00Z "Everyone wants to get rid of interferon and ribavirin because both have toxicity that make them often difficult to tolerate," Gordon notes. New Drugs for Hepatitis C On the Horizon 2011-03-30T21:45:00.247Z One of the new anti-HCV drugs, when given in combination with interferon and ribavirin, increases the percentage of patients who are cured of the virus to 60 and reduces overall treatment time. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z When added to the existing treatment — a combination of alpha interferon and ribavirin — telaprevir effectively cured 75 percent of patients, compared with 44 percent of those treated with the existing drugs alone. New Drugs Buoy Hopes in Fighting Hepatitis C 2010-07-22T00:40:00Z These patients were compared with a cohort taking quadruple therapy, consisting of these two antivirals plus interferon-α and ribavirin. Therapeutics: New drugs hit the target 2011-06-13T13:20:32.767Z The existing treatment is a combination of alpha interferon, which is injected, and ribavirin, an oral drug. Hepatitis C Drug Raises Cure Rate in a Late Trial 2010-05-26T02:39:00Z Typical treatment involves 52 weeks of interferon plus the antiviral drug ribavirin. Experimental compound potent against hepatitis C 2010-04-21T17:54:00Z McHutchison hopes that by early 2010, people who are diagnosed with HCV will be tested to see which mutations they possess in the immune genes that predict response to interferon and ribavirin treatment. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z In 2001 my treatment options included 48 weeks of a combination of interferon and ribavirin. 2010-01-11T01:51:00Z The standard therapy of interferon and ribavirin was given for either 24 weeks or 48 weeks, depending on how the patients were faring after four weeks and 12 weeks. Hepatitis C Drug Raises Cure Rate in a Late Trial 2010-05-26T02:39:00Z |
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