| 单词 | receptor |
| 例句 | It then begins dividing, replicating itself into a new colony of identical cells, all labeled with the same receptor, primed with the same question. The Lives of a Cell 1974-01-01T00:00:00Z Even though our receptors are not sensitive enough to hear it, there is comfort in knowing that the sound is there overhead, like the random noise of rain on the roof at night. The Lives of a Cell 1974-01-01T00:00:00Z There is a constant and surprisingly rapid turnover of the receptor cells, with new ones emerging from basal cells within a few days. The Lives of a Cell 1974-01-01T00:00:00Z They were attacking the cancer with a new cocktail: two chemo drugs and a protein receptor that they hoped would turn off the oncogene in Gus’s cancer. The Fault in Our Stars 2012-01-10T00:00:00Z They wander, as we do, searching for facts to fit their sparser stock of hypotheses, but when the receptor meets its match, there is only a single thud. The Lives of a Cell 1974-01-01T00:00:00Z Twisted into yet other shapes, they also form receptors, hormones, and signaling molecules, allowing cells to communicate with one another. The Gene 2016-06-02T00:00:00Z It is conceivable that new clones of cells with a particular receptor are stimulated to emerge in the process of training. The Lives of a Cell 1974-01-01T00:00:00Z But my saving human connection—my oxytocin receptor, as it were—is George, the nineteen-year-old Czech dishwasher who has been in this country exactly one week. Nickel and Dimed: On (Not) Getting By in America 2001-01-01T00:00:00Z Specific receptor proteins have been proposed, with different olfactory cells carrying specific receptors for different “primary” odors, but no one has yet succeeded in identifying the receptors or naming the “primary” odors. The Lives of a Cell 1974-01-01T00:00:00Z They carry specific information in their surface receptors, presented in the form of a question: is there, anywhere out there, my particular molecular configuration? The Lives of a Cell 1974-01-01T00:00:00Z She is, in fact, a winged receptor for caterpillars. The Lives of a Cell 1974-01-01T00:00:00Z There may even be odorants that fire off receptors in our olfactory epithelia without our being conscious of smell, including signals exchanged involuntarily between human beings. The Lives of a Cell 1974-01-01T00:00:00Z Olfactory receptors for communication between different creatures are crucial for the establishment of symbiotic relations. The Lives of a Cell 1974-01-01T00:00:00Z A rabbit, it has been calculated, has something like 100 million olfactory receptors. The Lives of a Cell 1974-01-01T00:00:00Z When the connection is made, and a particular lymphocyte with a particular receptor is brought into the presence of the particular antigen, one of the greatest small spectacles in nature occurs. The Lives of a Cell 1974-01-01T00:00:00Z Repeated exposure of an animal to the same odorant, in small doses, leads to great enhancement of acuity, suggesting the possibility that new receptor sites are added to the cells. The Lives of a Cell 1974-01-01T00:00:00Z Soy isoflavones bind to different receptors than actual estrogen and actually reduce the risk of breast and other types of cancer. "The key to a healthy, animal-free diet," according to a nutrition expert 2023-03-27T04:00:00Z I tried flooding and doing behavior training on myself, intentionally exposing myself to places and situation that deeply upset me to see if I could burn out my emotional receptors. Seven things I wish I'd known before my divorce: an optimistic guide to the future 2016-10-06T04:00:00Z Although researchers don't understand what causes these sensory alterations, the leading hypothesis is that the virus infects the cells that support the taste and smell receptors. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z A bit of an old Jack Benny radio skit pipes in from a receptor that resembles a dollhouse. ‘Salesman is Dead and Gone’ follows Willy Loman to the grave 2013-12-16T19:36:45Z We must respond to it rather as we respond to art: with all of our receptors alert, at all levels — rational, emotional and aesthetic. Perspective | Art can help distinguish between conspiracy and reality, and this exhibition proves it 2018-11-03T04:00:00Z The receptors that detect it might also be less sensitive or there might be fewer receptors. Eating certain foods can do the same thing as Ozempic and related drugs — without the side-effects 2023-03-21T04:00:00Z About a decade ago, a biologist at the University of California at San Diego named Charles Zuker isolated, for the first time, the receptors on the tongue that are responsible for our perception of taste. “Modern chicken has no flavor” — let’s make it in a lab 2013-03-17T16:00:00Z Androgen receptors on the human male larynx cause men’s vocal cords to thicken with the hormonal gush of puberty. Get to Know Your Larynx. Then Make Some Noise. 2021-02-10T05:00:00Z Some dishes send taste receptors into overdrive, like the squid tartar brushed with a thin layer of coconut oil and a drop of slightly spicy squid ink. In Spain, a Restaurant Reimagines the Famed El Bulli 2017-02-17T05:00:00Z Cheese proteins contain casomorphins, chemical compounds that attach to the same opiate receptors in the brain as heroin or morphine. And a Thinner New Year: Five New Books About Food and Diets 2016-12-28T05:00:00Z Warmth and cold receptors are located in the dermis, skeletal muscles, liver and an area of the brain known as the hypothalamus. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z The researchers also genetically engineered some mice to lack a type of cannabinoid receptor in their olfactory bulbs and subjected them to the same experiment. How weed causes the munchies 2014-02-12T13:30:00Z While the presence of genes encoding for functional taste receptors in our DNA allows us to detect food molecules, how we respond to these also depends on the unique combination of taste genes we carry. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z Stretch receptors in your skin, muscles and joints relay positional information to your central nervous system. Without your balance, life feels downside-up 2017-02-10T05:00:00Z Light touch and pressure receptors, which are located in the dermis, or middle layer of skin, are the ones that make this possible. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z The mammary gland in the breast in humans is filled with estrogen receptors and those actually make fat. A night at the vibrator museum 2012-05-20T00:00:00Z In other words, your receptors become confused if you stare into a computer screen late at night. 2010-01-20T00:22:00Z Many poisonous substances taste bitter, and that is why stimulating the bitterness receptors on the tongue sends the brain into alarm mode. Emptiness doesn't have to mean nothingness: it could mean happiness 2018-01-06T05:00:00Z Some people may have more sensitive TRPV1 receptors, for example – though Hayes, who’s looking into that now, says: “The jury is really still out on whether there is meaningful TRPV1 variation.” Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z PCSK9 is made in the liver and blocks LDL receptor molecules on cells that allow the body to get rid of harmful cholesterol. Cholestrol-lowering vaccine jab to stop heart attacks could be close 2017-06-20T04:00:00Z To test their hypothesis, they focused on a polymorphism in the CHRNA4 gene, which builds a certain kind of neural receptor that the neurotransmitter binds to. Do our genes make us more sensitive? 2013-01-24T22:40:00Z “The cold is going to help mask the burn, the viscosity is going to mask the burn, and the fat is going to pull the capsaicin off the receptor.” Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z Dopamine might have a role to play, but Megan’s medication, which worked by blocking dopamine receptors in the brain, had no effect. ‘I just knew he loved me. I could see it in his eyes’: can a psychologist cure lovesickness? 2018-05-25T04:00:00Z “Most cancers have receptors on their surface that bind to drugs like tamoxifen, but triple negative doesn’t,” Nithiyanandam explained. ‘It's not about your age, it's about your ideas’: the teen power list 2016-12-10T05:00:00Z This is a mutated gene that affects a type of dopamine receptor. This is why you are a couch potato: Laziness explained by science 2014-05-23T04:00:00Z The stretch receptors in the muscles connect directly to relaxation centers in the brain, he says. Yoga can make people cry. Here’s why that’s okay. 2021-11-02T04:00:00Z A positively or negatively charged molecule is passed through the cell membrane into a special receptor. The Spark of Life by Frances Ashcroft – review 2012-07-13T21:55:09Z Ross said psilocybin activates a sub-type of serotonin receptor in the brain. Magic mushroom ingredient psilocybin can lift depression, studies show 2016-12-01T05:00:00Z Stretch receptors in your rectum and bladder tell you when it’s time to visit the bathroom. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z Some of these cells were then exposed to acid and ammonium chloride and “the results showed that ammonium chloride activated the OTOP1 receptor just as effectively as acid.” Scientists suggest a sixth basic taste: ammonium chloride 2023-10-30T04:00:00Z One thing I couldn’t stop thinking about was how each person’s individual scent combines with another person’s individual scent receptors. Scents and Science Mingle in ‘The Joy of Sweat’ 2021-07-21T04:00:00Z They differ in form and potency, but they all interact with opioid receptors in the body, producing painkilling and euphoric effects. Deadly new trend: Fentanyl and other synthetic opioids sold as counterfeits 2016-08-30T04:00:00Z Pressure receptors in your arteries enable your brain to monitor and control your blood pressure. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z The absence of names should help create the ideal receptor: an open mind. Review: ‘Unknown Pleasures’ Makes Unfulfilled Promises 2017-02-10T05:00:00Z Each nonsugar sweetener has a unique chemical structure, but they all activate sweet taste receptors at very low concentrations. WHO’s recommendation against the use of artificial sweeteners for weight loss raises many questions 2023-06-08T04:00:00Z The interactions between taste receptors and food molecules give rise to the five basic taste qualities: sweetness, savoriness, bitterness, saltiness and sourness, which are transmitted from the mouth to the brain via specific nerves. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z The first taster is 5-HT, which, as I'm sure you don't need me to tell you, is the medical name for serotonin receptors, which control your moods. New music: The Good Natured – 5-HT (Loadstar remix) 2012-12-18T09:00:00Z “I live in a city environment. My home is a device to enable creativity. It’s my desert, it’s where I’m going to get those receptors open.” Can You Hear Agnes Martin’s Serenity in John Zorn’s Frenzied Music? 2016-11-29T05:00:00Z These receptors are highly responsive to edges and fine details. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z For decades scientists have known that the tongue responds strongly to ammonium chloride, but weren’t sure which receptors were responsible for being able to do so. Scientists suggest a sixth basic taste: ammonium chloride 2023-10-30T04:00:00Z Sensory receptors respond to light touch, pressure, stretching, warmth, cold, pain and vibration. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z And then, you do a little more research and realize that MSG is a synthetic additive, but that replicates a naturally occurring thing in your tasters, which is to activate your glutamate receptor. BonAp food boss Carla Lalli-Music: Not only is MSG okay, it is a core staple in the pantry 2019-03-30T04:00:00Z So, eventually, the caffeine breaks down, lets go of the receptors and all that adenosine that has been waiting and building up latches on and the drowsy feeling comes back — sometimes all at once. Nope, coffee won’t give you extra energy 2023-02-03T05:00:00Z It means that we can tick off malaria from the list of things that dogs can identify with the 220m olfactory receptors in their noses. Truffles, ghosts and now malaria: things dogs can sniff out 2018-10-30T04:00:00Z How much free adenosine is in your system that hasn't attached to receptors yet — and how drowsy you are as a consequence — will impact how much the caffeine you drink wakes you up. Nope, coffee won’t give you extra energy 2023-02-03T05:00:00Z Meanwhile a small study published in the journal Neuroscience Letters discovered receptors for stress hormones in taste buds. Mindfulness or cake? The battle against stress and comfort-eating 2014-07-01T04:00:00Z These acetylcholine receptors are distributed throughout the brain, and are especially involved in the functioning of dopamine in the striatum. Do our genes make us more sensitive? 2013-01-24T22:40:00Z Research in 2012 confirmed those unfortunate souls who find it soapy carry a particular olfactory receptor gene that makes it taste different to them. Why experts say you should go easy on picky eaters 2023-03-16T04:00:00Z But the dog nose has more than 200m smell- sensitive receptors, compared to 5m in a human nose, and these suggest a quite different set of priorities. Who’s a good boy? The unbreakable bond between humans and dogs 2021-01-24T05:00:00Z One of these receptors, the Pacinian corpuscle, responds to pressure and vibration. The power of touch: what will it be like when we can all connect again? 2021-02-28T05:00:00Z Your blood gets less oxygen as a result, which means that the receptors in charge of detecting taste and smell are less sensitive. Why does tomato juice taste SO much better on an airplane? 2022-07-30T04:00:00Z It was something like a sensation I couldn’t bear, but without the receptors to properly transmit the feeling. The Dentist Who Treated My Divorce 2022-04-01T04:00:00Z For now, the scientists behind the ammonium chloride study plan to explore the OTOP1 receptor’s response to ammonium chloride, hoping to uncover more about its evolutionary significance. Scientists suggest a sixth basic taste: ammonium chloride 2023-10-30T04:00:00Z A lunch special of panko-crusted shrimp in a thick tomato emulsion hits all the receptors: crunch and sweetness from the crustaceans; creamy acidity from the sauce. Choice Tables: Tasting ‘Modern Hungarian’ in Budapest 2013-05-10T18:11:57Z Like other touch receptors, TRPV1 receptors are found all over the inner layer of your skin, where they warn you of burn risk from midsummer asphalt, baking dishes straight from the oven, and the like. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z Hodges has also learned to structure the doses of his medication — including a dopamine inhaler, a receptor agonist patch and extended-release pills — in a way that supports his concert roster. A Pianist Adapts to Life With Parkinson’s Disease 2023-08-07T04:00:00Z But the result is startlingly delicious, hitting your brain’s receptors like a jackpot. 6 Standout Restaurants in Los Angeles Strip Malls 2016-12-20T05:00:00Z And all species have something that sounds as if it came from a Harry Potter novel: ampullae of Lorenzini, receptors that respond to electrical fields, which all animals generate. ‘Jaws’ Is Fiction. This Show Presents Sharks as Embattled Heroes. 2021-12-16T05:00:00Z Most intriguing, the genetically engineered mice with olfactory lobes that lacked cannabinoid receptors did not show increased scent sensitivity or appetite even when they were starved. How weed causes the munchies 2014-02-12T13:30:00Z “Scent” is a tidy noun to describe a tremendous riot of molecules volatile enough to fly up into our nasal cavities, where sensory receptors describe them to our brains. What in the World Is a $590 Scratch-and-Sniff T-shirt Doing in 2020? 2020-11-02T05:00:00Z Perhaps it was even genetic, the way monogamous prairie voles and their promiscuous cousins, the meadow voles, had differing amounts of oxytocin emitters or vasopressin receptors in their brains. My Boyfriend Has Two Girlfriends. Should I Be His Third? 2021-04-23T04:00:00Z Millennials have been sold a lie and our self-esteem and pleasure receptors are paying the price. Want good sex? Get married 2016-02-13T05:00:00Z This led the researchers to believe that the neostriatum’s opioid receptors activate an intense motivational system, driving the rats to pursue rewards. Where does gluttony come from? 2012-09-21T20:33:00Z When food enters the stomach, it triggers stretch receptors that in turn lead to the release of hormones which tell us we're full. Drinking a gallon of water a day probably won’t help you lose weight 2023-09-28T04:00:00Z It works by binding to the adenosine receptor, which it can do because it is a similar shape. Nope, coffee won’t give you extra energy 2023-02-03T05:00:00Z The THC in natural cannabis works by travelling through the blood to the brain, where it binds to cannabinoid receptors. 'It's worse than heroin': how spice is ravaging homeless communities 2017-04-15T04:00:00Z Andrew Chevallier, an author and medical herbalist, told me via email that we experience bitterness through molecules that stimulate taste receptors in our tongues, mouths and the stomach itself. Overeating on Thanksgiving? Bitters can make it better. 2019-11-19T05:00:00Z Using this theory, researchers are investigating how to reduce, rather than increase, appetite using CB1 receptors. Perspective | Marijuana gives you the munchies. What about CBD? 2019-01-07T05:00:00Z But to my taste receptors, dulled after years living in Sichuan, China, and in Thailand, too many dishes bordered on bland. In Asia, Tastes of the Sea 2015-02-19T05:00:00Z After giving the rats several weeks to acclimate to their new routines, researchers then dosed them with Naloxone, a drug that blocks dopamine receptors and induces immediate withdrawal symptoms. Exercising my demons 2012-10-14T13:00:00Z Even the value of fats or oils – which sounds like they ought to help wash capsaicin, which is fat soluble, off the receptors – is in dispute. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z Like ice cream, genes, including those for taste receptors, come in different flavors. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z Some pollutants trigger receptors that regulate detoxifying proteins — a good thing — but at the same time stimulate other inflammatory pathways that make the skin more sensitive and leach it of water. Wildfire Smoke Is Hurting Your Skin 2021-08-26T04:00:00Z As with hummingbirds, the human ability to discern what food tastes like depends on the presence of taste receptors. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z The human body contains special nerve endings called sensory receptors that enable you to “feel” things. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z For reasons that are certainly beyond me, outrageously terrible film and television often stumbles into the quadrant of neural receptors that read for hilarity. James Franco’s lesbian vampires: For prestige drama overload, a self-aware Lifetime spoof could be the campy antidote 2016-04-07T04:00:00Z According to James Sinka, a practitioner of dopamine fasting, “Your brain and your biology have become adapted to high levels of stimulus so our project is to reset those receptors so you’re satiated again.” 13 Ways to Be a Better Person in 2020 2019-12-27T05:00:00Z Some, though, were hopeful of a new combined HRT drug that contains equine oestrogen and bazedoxifene, a selective oestrogen receptor modulator, that can modulate any damaging effects of oestrogen on uterus and breast tissue. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z The gene turned out to encode a receptor – eventually named TRPV1, and pronounced “trip-vee-one” – that is activated not just by capsaicin but also by dangerously hot temperatures. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z “We know from the science of what goes on under the skin that when the skin is moved, pressure receptors are stimulated,” she says. No hugging: are we living through a crisis of touch? 2018-03-07T05:00:00Z Made from miracle berries, the substance blocks some sweet receptors while making strong acids taste sweet. Taste preference is the subject of a new book by a Silver Spring writer 2015-01-25T05:00:00Z From the medical standpoint, he explains, “the big problem with those hypotheses is that we don’t know if there are receptors on our tongues/mouths/throats for the hormones in someone else’s saliva.” The science of swooning: We don’t really know why some kisses lead to back kicks, toe curls and weak knees 2016-02-14T05:00:00Z That disruption would cause the dopamine to build up in the synapse and super-hella overstimulate the receptors, which, in seconds, would feel to her like aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaah—the bliss of all bliss. The “I Do” of Addiction 2019-03-04T05:00:00Z TRPA1, which Julius calls the “wasabi receptor”, causes the sensation of heat from wasabi, horseradish and mustards, as well as onions, garlic and cinnamon. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z The Alfredo sauce, sweetly dripping from the fettuccine like rain from a leaf, hit me like a prescription opiate that had been specifically engineered for my opiate receptors. Can Fancy Chefs Excel at Fast, Cheap Food? Two Case Studies 2018-01-23T05:00:00Z These galleries are full of things that are meant to delight, to appeal to aesthetic receptors independent of politics. Perspective | I returned to the National Gallery seeking comfort. But art no longer feels like an escape. 2020-10-06T04:00:00Z This could be because of differences in the genes that code for GLP-1, the receptors or parts of the pathways that regulate production. Eating certain foods can do the same thing as Ozempic and related drugs — without the side-effects 2023-03-21T04:00:00Z Oestrogen is involved in a range of bodily functions, and oestrogen receptors are found in cells throughout the body: the brain, the breasts, the bones, the belly. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z A third element involves the more complex dance between our olfactory receptors and as many as 20 volatile organic compounds at work in tomatoes. The quest for the perfect tomato 2015-09-15T04:00:00Z To further complicate matters, the receptors that detect caffeine and the other bitter compounds are highly variable between individuals due to genetics and training from our usual exposures. Just because your coffee is bitter, doesn’t mean it’s "stronger" 2022-10-27T04:00:00Z It just uses the serotonin you have and it doesn't allow it go back into the receptor. Does Prozac help artists be creative? 2013-05-19T06:00:00Z When cooking, think about when and how your bitter component is being incorporated, as that will likely determine when that same bitterness will spark your diner's taste receptors. Looking to take your cooking to the next level? Don't shy away from bitterness 2023-01-27T05:00:00Z The problem is that the brain fights back, increasing the number of receptors for serotonin. Anorexia: you don’t just grow out of it | Carrie Arnold 2016-03-29T04:00:00Z These receptors are not located only in your skin. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z Because of its shape, THC fits into these receptors, too. Is recreational pot use safe? 2013-05-23T12:18:00Z For instance, when sugar binds to the sweet receptor, it signals sweetness. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z However, hair follicles, which are located in the dermis, are surrounded by touch receptors. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z We don’t take pleasure in eating food that’s still searingly hot from the oven, even though that delivers exactly the same sensation we get from chillies: same receptors, same nerves. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z For comparison, the three light receptors in the human eye allow us to see an estimated 10 million colors. The human nose can distinguish between 1 trillion different scents 2014-03-23T21:00:00Z These stress hormones prevent oxytocin from binding to brain receptors, tipping the balance towards distrust and away from pro-social behaviour. Oxytocin: could the 'trust hormone' rebond our troubled world? 2011-08-20T23:08:00Z Stretch receptors are located in your dermis, muscles and joints. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z Many more variants exist in our gene repertoire, including those for the sweet taste receptor. Can we train our taste buds for health? A neuroscientist explains how genes and diet shape taste 2023-06-20T04:00:00Z It also seems to hotwire the happiness receptors in the brains of small children – show me a club on this planet that goes harder than an elementary school hosting Lil Nas X. I need a hero: finding courage, defiance and joy in the dark days of 2019 | Josephine Tovey 2019-12-25T05:00:00Z This is not the first time a company has attempted to create a weight-management product by acting on the CB1 receptor. Counterculture to Counterintuitive: Cannabis to Help You Diet? 2022-01-01T05:00:00Z The scientists searched for a stem cell donor carrying a genetic mutation that prevents expression of an HIV receptor called CCR5. Hopes rise for Aids cure after bone-marrow transplant rids man of HIV 2019-03-05T05:00:00Z A less well-understood mechanism is that progestins, which are often created by changing the molecular structure of testosterone, aren’t an exact match for our progesterone receptors. Dr Sarah E Hill: ‘We have a blind spot about how the pill influences women’s brains’ 2019-10-19T04:00:00Z The capsaicin chemical that bludgeoned their heat receptors causes pain but then blocks it. Taste preference is the subject of a new book by a Silver Spring writer 2015-01-25T05:00:00Z Frequently overeating highly palatable foods saturates the brain with so much dopamine that it eventually adapts by desensitizing itself, reducing the number of cellular receptors that recognize and respond to the neurochemical. Junk food is tricking your brain: The depressing science behind your binging 2015-12-27T05:00:00Z The quality of Traverse productions in 2010 has been a continual delight; the trio of plays I saw this week seemed to tickle every receptor. Edinburgh fringe theatre: Sub Rosa; Of Women and Horses I Have Known; Long Live the King; The Author; My Romantic History; Speechless 2010-08-14T23:05:00Z “When you start falling in love, your brain releases the chemical dopamine, which activates your neural receptors and makes you feel both pleasure and a euphoric sense of purpose,” Dr. Fisher said. When a Love Expert Falls in Love 2020-08-21T04:00:00Z Without information from our 400 smell receptors, which can detect many millions of smells, food flattens out. Will Fish Sauce and Charred Oranges Return the World Covid Took From Me? 2021-03-02T05:00:00Z Haidt claims that just as we have the taste receptors of salt, sweet, bitter, and so on, so we generally work on five basic moral receptors: those pertaining to caring, fairness, loyalty, authority and sanctity. The Righteous Mind: Why Good People Are Divided by Politics and Religion by Jonathan Haidt – review 2013-05-07T11:32:26Z “There’s a specific receptor in the mitochondria of the skin cells that red light specifically acts upon,” he said. Can One LED Light Give You Perfect Skin? 2019-10-23T04:00:00Z “With people who have lost their sense of smell, I think it takes a longer time for the receptors to work and to feed that into the brain,” she explained. Will Fish Sauce and Charred Oranges Return the World Covid Took From Me? 2021-03-02T05:00:00Z The synthetic version does the same thing, but can be 100 times more potent, binding to the receptors more efficiently and in some cases for far longer. 'It's worse than heroin': how spice is ravaging homeless communities 2017-04-15T04:00:00Z Human beings have 400 types of scent receptors. Can Scent Be Democratized? 2022-03-18T04:00:00Z In a rare move, the FDA explicitly stated in a press release that Belviq “does not appear to activate” a receptor that was linked to the heart problems seen with fen-phen. FDA approves diet pill 2012-06-27T17:50:00Z But another would be to say that Mr. Lisicky has a gift for understanding suffering, an added bundle of receptors for detecting loneliness. Review: In ‘The Narrow Door,’ Paul Lisicky Opens a Window on Friendship 2016-01-17T05:00:00Z The work of touch is done by sensory receptors, buried in the skin at different depths according to what kind of stimulus they detect, such as warmth, cold or pain. The power of touch: what will it be like when we can all connect again? 2021-02-28T05:00:00Z Chemical messengers like serotonin affect the extent to which we are spiritual: The number of serotonin receptors in the brain corresponds to scores for spirituality. This is your brain on religion: Uncovering the science of belief 2014-01-04T19:00:00Z They all line up, reacting clownishly to a scratch tape of their names being called, as if their whole bodies were sound receptors. Cedar Lake Contemporary Ballet – review 2012-10-12T11:23:48Z Stretch receptors in your lungs tell you when you’ve taken a full breath. Ever wondered about your sense of touch? 2016-06-24T04:00:00Z Chemically, it blocks the receptors on our taste buds that receive bitter flavors. Welcome to flavor country: why New York City's salt warning is a good thing 2015-12-02T05:00:00Z Another hypothesis, the gate control theory of pain, argues that the body shuts down pain receptors in response to acupuncture’s needling. So you want to give acupuncture a try. How do you pick a provider? 2021-10-03T04:00:00Z Wonky nerve receptors that scream in pain rather than perceive penetration as neutral or pleasurable? Anal sex: Science’s last taboo 2012-10-05T23:30:00Z Once our brains sense umami through the taste receptors on our tongues, our bodies prime our digestive tracts to absorb protein more easily. Does chicken soup really help when you’re sick? A nutrition specialist explains 2023-10-23T04:00:00Z Curiously, TRPA1 is also the heat receptor that rattlesnakes use to detect their prey on a dark night. Feel the burn: why do we love chilli? 2017-04-23T04:00:00Z While THC makes you feel high, CBD targets receptors in your body that make you feel self-satisfied and smug. Not-to-Be-Missed Shouts of 2019 2019-12-16T05:00:00Z Ketamine blocks a brain receptor called NMDA, which is required for the formation of memories. Radical ketamine therapy could treat alcohol addiction 2017-01-24T05:00:00Z “It says something about them, that their antennas and receptors are open to something deeper,” said Milliken, who made the news last year for protesting outside Bill Cosby’s Pennsylvania home. Golden-Con Threw a Party, Invited Every ‘Golden Girls’ Fan It Knew 2022-05-04T04:00:00Z The ineffable magic that occurs when gorgeous molecules of smell and taste stimulate our pleasure receptors is best left to imagination — unless, that is, you are Proust. A Scented Diary of a Lockdown 2020-06-03T04:00:00Z I particularly like this line - "hit me like a prescription opiate that had been specifically engineered for my opiate receptors." Can Fancy Chefs Excel at Fast, Cheap Food? Two Case Studies 2018-01-23T05:00:00Z There is also evidence that the oxytocin receptors in rats' forebrains tend to atrophy when maternal nurturing is "insufficient". Oxytocin: could the 'trust hormone' rebond our troubled world? 2011-08-20T23:08:00Z "This could result in new ways to treat patients. For example, one could develop synthetic hormones designed to target the receptors on specific cells," Ravnskjaer adds. Hormones have the potential to treat liver fibrosis 2023-11-16T05:00:00Z The scientists achieved this result again by removing the receptors for the hunger hormone ghrelin from these neurons. Hunger hormones impact decision-making brain area to drive behavior 2023-11-16T05:00:00Z Gefapixant works by blocking receptors that stimulate the nerves and trigger the urge to cough. US FDA staff flags concerns on Merck's chronic cough drug 2023-11-15T05:00:00Z Until now, it was assumed that such receptors only occur in bony vertebrates. Evolution of taste: Early sharks were able to perceive bitter substances 2023-11-13T05:00:00Z These compounds often dock onto protein, which usually are enzymes or receptors that trigger a specific chain of physiological actions. AI programs spat out known data and hardly learned specific chemical interactions when predicting drug potency 2023-11-13T05:00:00Z The researchers will now continue studying stellate cells and their surface receptors in patient samples. Hormones have the potential to treat liver fibrosis 2023-11-16T05:00:00Z Prior studies have shown that the hippocampus of animals, including non-human primates, has receptors for ghrelin, but there was scant evidence for how these receptors work. Hunger hormones impact decision-making brain area to drive behavior 2023-11-16T05:00:00Z Humans and other bony vertebrates experience bitterness thanks to taste 2 receptors, or T2Rs, which are proteins that transmit taste information to the brain. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z Twelve out of seventeen cartilaginous fish genomes studied contained genes for the taste receptors type 2, with only one T2R gene present in each species. Evolution of taste: Early sharks were able to perceive bitter substances 2023-11-13T05:00:00Z They discovered that Vg1-Nodal heterodimers do not need to undergo cleavage before they are released from the cell to bind with receptors on target cells. Team creates synthetic enzymes to unravel molecular mysteries 2023-11-09T05:00:00Z FH patients still make some LDL receptors, and Verve’s strategy is to keep those molecules around for longer by altering the liver’s gene for PCSK9, an enzyme that normally removes the receptors from cells. Base editing, a new form of gene therapy, sharply lowers bad cholesterol in clinical trial 2023-11-11T05:00:00Z These side effects arise from the fact that humans have ten different versions of the Wnt signaling receptor, Frizzled, with distinct functions. Side-effect avoiding treatment shows early promise against breast cancer in mice 2023-11-09T05:00:00Z That led many to assume these receptors had evolved after their lineage split from the bony vertebrates. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z A screening of ninety-four human bitter substances identified eleven substances that could also activate the sharks' receptors. Evolution of taste: Early sharks were able to perceive bitter substances 2023-11-13T05:00:00Z Blocking the receptors for these neurotransmitters on nearby neurons meant that they no longer fired when the hair was stroked, confirming the link between the follicle cells and the neurons’ response. A Hairy Truth About Your Sense of Touch 2023-11-08T05:00:00Z When the gene is mutated, it overproduces the corresponding human epidermal growth factor receptor 2 protein to trigger unhinged cell division. Precision Cancer Drugs Glitter with Promise—If You Can Get Them 2023-11-03T04:00:00Z Researchers have therefore recently developed new Wnt signaling inhibitors that could reduce side effects by targeting just three of these receptors. Side-effect avoiding treatment shows early promise against breast cancer in mice 2023-11-09T05:00:00Z Yet sharks and other cartilaginous fish do have smell receptors closely related to bitter taste receptors. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z In particular, the Papilio xuthus, a yellow, Asian swallowtail butterfly, has not only blue, green and red, but also violet, ultraviolet and broadband receptors. Seeing the unseen: How butterflies can help scientists detect cancer 2023-11-03T04:00:00Z Murphy shared that his favorite example from the project is the odorant receptors from the fishing cat, an aquatically adapted wild cat species living in Southeast Asia. New secrets about cat evolution revealed 2023-11-02T04:00:00Z They added common genetic variants for the GPCRs humans carry, and documented significant differences in how these mutated receptors responded when activated. Scientists train AI to illuminate drugs' impact 2023-10-31T04:00:00Z These specialized neurons express a receptor that has a role in blood vessel constriction. Heart-brain link offers new potential explanation for fainting 2023-11-01T04:00:00Z In the lab, the researchers implanted genes for these receptors from two of the species—bamboo sharks and catsharks—into human kidney cells, then exposed them to 94 bitter substances. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z By sticking to a receptor called c-Mpl on the surface of platelets, PF4 triggered the production of the small cells known to cause clotting. Protein interaction causing rare but deadly vaccine-related clotting found 2023-10-30T04:00:00Z At cellular level, coronavirus spike proteins are cleaved, or split in two, after binding to their receptors. Discovery concerning receptors used by coronaviruses to enter human cells 2023-10-27T04:00:00Z "We all think of ourselves as more or less normal, but we are not. We are all basically mutants. We have tremendous variability in our cell receptors," Martemyanov said. Scientists train AI to illuminate drugs' impact 2023-10-31T04:00:00Z When they blocked the receptor for these neurotransmitters on the sensory neurons, the neurons no longer responded to the hair follicle cell stimulation. Hidden way for us to feel touch 2023-10-27T04:00:00Z Several of those compounds also trigger receptors in bony fish such as zebrafish and the “living fossil” coelacanth, and all of them taste bitter to humans. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z When these signals bind to receptors on the sperm's surface, it triggers a series of events, starting their movement towards the egg. Sperm's secret voltage switch: Scientists unlock the mystery of motility 2023-10-25T04:00:00Z These human-pathogenic viruses' use of different receptors probably affects their degree of severity. Discovery concerning receptors used by coronaviruses to enter human cells 2023-10-27T04:00:00Z There are many different capsaicinoids, and these compounds react with a nerve receptor that only mammals have that sends a signal to our brain saying, “This is hot.” How Hot Is ‘Pepper X’? Its Creator Spent 6 Hours Recovering from Eating It 2023-10-26T04:00:00Z "That receptor sequence is the major determinant -- not signaling proteins such as cytokines or other blood components," said Daniel Chen, first author of the paper. Breakthrough T cell discovery has huge potential for engineering custom immune responses 2023-10-25T04:00:00Z The sharks’ receptors also perked up when exposed to bitter substances that would be created inside their bodies, such as bile acids. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z Last year the research team demonstrated that ABA receptor proteins can be trained to bind to chemicals other than ABA. Plants transformed into detectors of dangerous chemicals 2023-10-23T04:00:00Z "Previous efforts to target this receptor have been unsuccessful. But now that we've identified this epitope, there could be a therapeutic path forward to target Fas in tumors," Tushir-Singh said. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z Studies suggest that both may be mediated in part by the brain's μ-opioid receptors, which process pain. Ketamine's effect on depression may hinge on hope 2023-10-19T04:00:00Z "It is that receptor sequence -- the proteins on the T cell that bind to foreign antigens -- that determines what this cell's phenotype is, and thus determines what its function is going to be." Breakthrough T cell discovery has huge potential for engineering custom immune responses 2023-10-25T04:00:00Z The first vertebrate bitterness receptors, he argues, likely detected either internal or external substances, then gradually evolved to do both. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z Additional proteins, called receptors, help the plant recognize and respond to ABA. Plants transformed into detectors of dangerous chemicals 2023-10-23T04:00:00Z Immunotherapies, such as CAR T-cell-based immune therapies and immune checkpoint receptor molecule activating antibodies, have shown tremendous promise to break this cycle. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z "It also points to some potential therapeutic strategies, such as blocking BNP's ability to bind to NPR1 receptors in the skin." BNP peptide a culprit in eczema 2023-10-19T04:00:00Z Scientists have traced estrogen receptors, proteins that direct the hormone to the right place in the body, back to 600 million years ago. Challenging prehistoric gender roles: Research finds that women were hunters, too 2023-10-20T04:00:00Z But the fact that receptors from two relatively closely related sharks reacted to many of the same bitter compounds isn’t surprising, Zhao notes. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z Now the team has shown that once the receptors bind to this other chemical, the plant will turn beet red. Plants transformed into detectors of dangerous chemicals 2023-10-23T04:00:00Z "It doesn't matter how well we engineer the immune receptor activating antibodies and T cells if they cannot get close to the tumor cells. Hence, we need to create spaces so T cells can infiltrate." Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z These receptors, which can be seen as 'traffic directors,' transmit signals from the outside to the inside of cells and are involved in many physiological processes. Restoring the function of a human cell surface protein in yeast cells 2023-10-19T04:00:00Z To date, optogenetics has been primarily employed in the brain, an area that lacks pain receptors, which allows for the relatively painless implantation of rigid devices. Soft optical fibers block pain while moving and stretching with the body 2023-10-19T04:00:00Z He wishes they’d run the experiment with bitter taste receptors from more species—such as sawfish—to see whether it produced the same results. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z The precise mechanisms of these receptors, especially the elusive C5aR1, have remained a mystery. Unlocking secrets of immune system proteins: A potential path to new treatments 2023-10-17T04:00:00Z Death receptors do precisely what their name implies -- when targeted, they trigger programmed cell death of tumor cells. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z The estrogen receptor—the protein that estrogen binds to in order to do its work—is deeply ancient. The Theory That Men Evolved to Hunt and Women Evolved to Gather Is Wrong 2023-10-17T04:00:00Z Psychoactive molecules primarily change brain function through the receptors on the neural cells. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z If so, that would offer more certainty that the ancestral bitter receptor truly resembled the sharks’ T2R1s. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z The study's revelations suggest potential avenues for the development of drugs targeting these receptors to treat various diseases, added Gati, who heads USC's cryo-EM facility, which is available for use by researchers around the globe. Unlocking secrets of immune system proteins: A potential path to new treatments 2023-10-17T04:00:00Z Developing drugs that boost death receptor activity could provide an important weapon against tumors. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z Joseph Thornton of the University of Chicago and his colleagues have estimated that it is around 1.2 billion to 600 million years old—roughly twice as old as the testosterone receptor. The Theory That Men Evolved to Hunt and Women Evolved to Gather Is Wrong 2023-10-17T04:00:00Z The serotonin receptor 5HT, the one famously tweaked by antidepressants, comes in a variety of subtypes. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z The bitter taste receptor identified in a pair of shark species may mirror a sort of all-purpose bitterness detector that our common ancestor possessed. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z This process produces protein messengers, C3a and C5a, which in turn activate specific receptors on cells, setting off a cascade of internal signals. Unlocking secrets of immune system proteins: A potential path to new treatments 2023-10-17T04:00:00Z In fact, the study showed tumors with a mutated version of the epitope of Fas receptors will not respond to CAR T at all. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z Females also tend to have a greater number of estrogen receptors on their skeletal muscles compared with males. The Theory That Men Evolved to Hunt and Women Evolved to Gather Is Wrong 2023-10-17T04:00:00Z This receptor also appears to mediate the hyperplastic states when a brain is changing quickly. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z However, despite extensive research, the specific tongue receptors that react to it remained elusive. And then there were 6 -- kinds of taste, that is 2023-10-05T04:00:00Z These images unveil how the receptors interact with molecules, change shape upon activation and transmit signals within the cell. Unlocking secrets of immune system proteins: A potential path to new treatments 2023-10-17T04:00:00Z Taste receptors on the human tongue convert chemical data into electrical impulses. Could future AI crave a favorite food? 2023-10-04T04:00:00Z In their study, the team designed organic molecules that selectively target receptors overexpressed in the membranes of aging cells. Selective removal of aging cells opens new possibilities for treating age-related diseases 2023-10-04T04:00:00Z It's only the 5-HT2A receptor inside the cell that facilitates rapid change in neuronal structure. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z Hydrogen ions from these acidic substances move into taste receptor cells through the OTOP1 channel. And then there were 6 -- kinds of taste, that is 2023-10-05T04:00:00Z While humans have about five million smell receptors, dogs possess up to a billion and can communicate with one another with chemical signals. What Colors Do Dogs See? 2023-10-04T04:00:00Z These odorants latch on to one of 400 receptors in the nose, called olfactory receptor neurons, which then send a signal the brain. The study of smell loss still struggles for support 2023-10-04T04:00:00Z The fact their outer surfaces feature some of the same receptors as typical immune cell targets hints at why and how they harbor the parasites, Satoskar said. A lethal parasite's secret weapon: Infecting non-immune cells 2023-09-29T04:00:00Z The psychedelics, on the other hand, slip through the cell's exterior and tweak the 5-HT2A receptor, stimulating dendritic growth and increased spine formation. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z Naloxone, also known by the brand name Narcan in a nasal spray form, works by knocking opioids out of brain receptors, reversing overdose symptoms. With fentanyl’s arrival, WA’s music scene turns to education, naloxone 2023-10-01T04:00:00Z It turns out that dogs possess two types of color-sensing receptors, called cones, in their retinas. What Colors Do Dogs See? 2023-10-04T04:00:00Z Plus, cone receptors are less reliable in dim environments. Streetlights Are Mysteriously Turning Purple. Here’s Why 2023-09-27T04:00:00Z It wasn’t until later, about 110 million years ago, that the beetles’ ability to make toxic chemicals that activate pain receptors evolved. The Secret to Beetles’ Unfathomable Diversity 2023-09-27T04:00:00Z One study found that people who report feeling more pain than others are likely to carry a Neanderthal pain receptor. We carry DNA from extinct cousins like Neanderthals. Science is now revealing their genetic legacy 2023-09-24T04:00:00Z They found that the sympathetic nerves were producing noradrenaline, which was binding to killer T cells using a receptor called ADRB1. Reducing stress on T cells makes them better cancer fighters 2023-09-20T04:00:00Z The tapetum, which some other animals, such as cats and cattle, also possess, sits behind the retina and reflects light back onto it, giving the receptors a second chance to gather more visual detail. What Colors Do Dogs See? 2023-10-04T04:00:00Z The receptor is defined by five-sided, or pentameric, assemblies derived from 19 different subunits, each of which give rise to a vast number of configurations that may or may not be clinically relevant. Structure of crucial receptor in brain development, function 2023-09-20T04:00:00Z Targeting acetylcholine receptors can change pain responses, but the mechanisms by which naturally produced acetylcholine regulates pain control circuitry in the vIPAG had not been explored. Alternative pain control circuits in the brain produce relief similar to opioids without the downsides 2023-09-20T04:00:00Z Another found that a third of women in Europe inherited a Neanderthal receptor for the hormone progesterone, which is associated with increased fertility and fewer miscarriages. We carry DNA from extinct cousins like Neanderthals. Science is now revealing their genetic legacy 2023-09-24T04:00:00Z Exhausted killer T cells expressed more ADRB1 receptors than their functional counterparts, allowing the T cells to "listen" to the noradrenaline released by the nerves. Reducing stress on T cells makes them better cancer fighters 2023-09-20T04:00:00Z For instance, researchers know that opioid drugs suppress pain in mice, but no one knows whether pain receptors in different cephalopod species respond in the same way. Octopuses Used in Research Could Receive Same Protections as Monkeys 2023-09-20T04:00:00Z They were then able to visualize three major structural populations of the receptor. Structure of crucial receptor in brain development, function 2023-09-20T04:00:00Z The ⍺7 receptor is usually an excitatory receptor, meaning that it generates more activity in the nervous system. Alternative pain control circuits in the brain produce relief similar to opioids without the downsides 2023-09-20T04:00:00Z This is significant as TRPA1 is a family of neuron receptors that are involved in sensory neural response to a variety of chemical irritants found in foodstuff and other medicines. Markers can predict how children will tolerate sweetened medicine 2023-09-18T04:00:00Z Surprisingly, the ADRB1 receptor provided the T cells with critical instructions to migrate near the nerves, which in turn suppressed their functions -- making them worse at fighting cancer. Reducing stress on T cells makes them better cancer fighters 2023-09-20T04:00:00Z These benefits may be linked to the fact that THC and CBD bind themselves to proteins in the brain and body known as cannabinoid receptors. Marijuana can often help with autism symptoms, but it's complicated. A new study indicates why 2023-09-17T04:00:00Z Scientists have revealed the molecular structure of a type of receptor that's crucial to brain development and function. Structure of crucial receptor in brain development, function 2023-09-20T04:00:00Z That's because the acetylcholine receptor is part of a different pathway than that used by opioids -- the two operate independently, and if tolerance develops in the opioid circuits, acetylcholine's effects are not altered. Alternative pain control circuits in the brain produce relief similar to opioids without the downsides 2023-09-20T04:00:00Z In addition to tagging engram cells, we labeled cells with optogenetic receptors, which are ion channels that are activated by light. Forgotten Memories May Remain Intact in the Brain 2023-09-15T04:00:00Z Like psilocybin, it targets serotonin receptors in the brain, which drives the hallucinogenic effects, but the length of the trip is reduced to about an hour. The firms hoping to take psychedelic drugs mainstream 2023-09-14T04:00:00Z Taken together, they can produce a sort of synergistic effect, because CBD is a negative allosteric modulator, meaning it can change how THC binds to these receptors, though this complex relationship is often oversimplified. Marijuana can often help with autism symptoms, but it's complicated. A new study indicates why 2023-09-17T04:00:00Z Among the new mutations that BA.2.86 carries, 14 reside within an area of the spike protein called the receptor binding domain, which binds to the receptors on host cells. How evasive and transmissible is the newest omicron offshoot, BA.2.86? 4 questions answered 2023-09-14T04:00:00Z The results of this work point to multiple opportunities to develop new pain-relieving drugs, either by stimulating the release of acetylcholine or targeting ⍺7 receptors. Alternative pain control circuits in the brain produce relief similar to opioids without the downsides 2023-09-20T04:00:00Z Methadone is a full agonist of the mu opioid receptor, meaning that when the drug meets the receptor in the brain, it activates it, causing a biochemical reaction that leads to euphoria and pain relief. Vivitrol, Used to Fight Opioid Misuse, Has a Major Overdose Problem 2023-09-13T04:00:00Z “Autism manifests itself in a thousand ways in different people. But it means he doesn’t have good receptors for other people’s emotions, nor does he have a craving to make people like him.” Manic moods and 3 a.m. texts: How Walter Isaacson navigated Elon Musk and his demons 2023-09-12T04:00:00Z The drug works to reverse overdoses by binding to the body’s opioid receptors and blocking other opioids such as heroin or fentanyl. Police give OD-reversing drug to puppy after possible fentanyl exposure 2023-09-09T04:00:00Z The receptors, said Hurd, who heads an addiction research lab at the Icahn School of Medicine at Mount Sinai, are “really critical for so many processes in the brain.” As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z McGehee said medications targeting these receptors have been tested for multiple diseases, but not yet as painkillers. Alternative pain control circuits in the brain produce relief similar to opioids without the downsides 2023-09-20T04:00:00Z However, naltrexone, in both short- and long-acting forms, has the opposite pharmacology: it antagonizes mu receptors, occupying them without activating them. Vivitrol, Used to Fight Opioid Misuse, Has a Major Overdose Problem 2023-09-13T04:00:00Z But the team also found these cat receptors are uniquely tuned to molecules found at high concentrations in tuna, revealing why our feline friends seem to prefer this delicacy over all others. Why do cats love tuna so much? Scientists may finally know 2023-08-25T04:00:00Z In a study published Tuesday in Nature Communications, they found these blue light receptors were actually buried below the color-changing cells in the fish. This fish changes its color like a chameleon. New research suggests it can "see" with its skin 2023-08-22T04:00:00Z Adolescents are especially vulnerable, Hurd told the Zoom audience, because the endocannabinoid system—a network of natural signaling molecules structurally similar to THC, along with their receptors—plays a central role in brain development. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z While it shares about 30 of the same spike mutations, which allow the virus to attach itself more easily to receptors in cells, it also has 30 unique ones. A new COVID variant nicknamed "Pirola" is raising global alarm but don't freak out yet 2023-08-20T04:00:00Z While it protects people from overdose by blocking the biochemistry that opioid receptors initiate, this protection may decline during the last week before their next monthly shot. Vivitrol, Used to Fight Opioid Misuse, Has a Major Overdose Problem 2023-09-13T04:00:00Z Cats also have fewer bitter taste receptors than humans do—a common trait in uber-carnivores. Why do cats love tuna so much? Scientists may finally know 2023-08-25T04:00:00Z The eyes’ retinas don’t have any pain receptors, so people often have no idea if they are staring at the sun long enough to do damage. Here’s what happens to your eyes if you look directly at the sun 2023-08-18T04:00:00Z A longitudinal study of 799 European adolescents published in 2021 linked cannabis use with a thinning of the prefrontal cortex in regions where cannabinoid receptors are expressed, and with higher levels of impulsiveness. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z However, stimulating nerves through transient receptor potential channels can reverse the contraction. Spicy candies relieve nighttime leg cramps like magic 2023-08-16T04:00:00Z These sensitized receptors may make relapse even more dangerous than after abstinence or other meds. Vivitrol, Used to Fight Opioid Misuse, Has a Major Overdose Problem 2023-09-13T04:00:00Z To double check, he and his team engineered cells to produce the cat umami receptor on their surface. Why do cats love tuna so much? Scientists may finally know 2023-08-25T04:00:00Z “It literally only does one thing,” Perry continued, which is binding to the opioid receptors in the body, kicking off the opioids and causing a person to breathe again. What to know about fentanyl safety at festivals and other events 2023-08-11T04:00:00Z In women who had smoked cannabis, Hurd and Dow-Edwards found alterations to the fetal brain’s dopamine system, including reduced expression of dopamine receptors in the amygdala and nucleus accumbens, a reward center. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z One of the differences between EG.5 and its immediate ancestor is that it has another spike protein mutation that effectively allows the virus to attach to receptors in cells even more easily. Latest COVID mutation EG.5 seems to be driving a recent surge in cases 2023-08-08T04:00:00Z Some of the genes that had the strongest effect on diet, which I find most compelling, are the taste receptor, olfactory receptor and digestive enzyme genes. Your Genes May Influence What You Like to Eat 2023-08-01T04:00:00Z But in cats, the nucleotides activated the receptor, and the amino acids further boosted it, McGrane says. Why do cats love tuna so much? Scientists may finally know 2023-08-25T04:00:00Z Naloxone can take 30 seconds to a few minutes to bind to the brain receptors, reversing overdose symptoms such as slow breathing, tiny pupils and loss of consciousness. What to know about fentanyl safety at festivals and other events 2023-08-11T04:00:00Z Methadone, the other medication commonly used in opioid treatment, doesn’t have the same problem because it activates receptors at a 100% level. Fentanyl addiction is tough to kick. Has WA found ‘the secret sauce’ in health ‘hub’ model? 2023-07-23T04:00:00Z If fentanyl remains in the system, activating receptors at a higher level, the medication could make them feel worse, not better. Treating fentanyl addiction is complicated. Here’s how WA doctors are adapting 2023-07-23T04:00:00Z This includes the bitter taste receptor gene—most prominently known for influencing intake of cruciferous vegetables, such as Brussels sprouts. Your Genes May Influence What You Like to Eat 2023-08-01T04:00:00Z Heavy pruning is harmful because trees use their leaves as solar receptors for photosynthesis, Hodel said. Severe pruning during summer's heat is hell for trees, not just striking actors 2023-07-21T04:00:00Z Gaslighting is now part of the conversational lexicon about life today, with women often its immediate receptors. Review: Wit and fury merge in Judith Bernstein's new paintings that scream 'Snap out of it' 2023-07-18T04:00:00Z It said one particular receptor for the virus appeared not to be present in Amish and Ashkenazi Jews. Robert F. Kennedy Jr. Airs Bigoted New Covid Conspiracy Theory About Jews and Chinese 2023-07-15T04:00:00Z Semaglutide, which was initially developed as a diabetes treatment, is a type of agonist—a substance that binds to specific receptors in the body and prompts a reaction. Could New Weight-Loss Drugs like Ozempic Treat Addiction? 2023-07-12T04:00:00Z But the olfactory receptor genes we identified were so specific. Your Genes May Influence What You Like to Eat 2023-08-01T04:00:00Z Retatrutide interacts with three receptors that determine appetite, which is probably why it’s so effective, she adds. Beyond Ozempic: New Obesity Drugs Could Be Cheaper and Even More Effective 2023-07-05T04:00:00Z Ultimately, he says, researchers hope to map the solubility of various scents to the locations of specific smell receptors in cats’ noses. Cat Noses Contain Twisted Labyrinths That Help Them Separate Smells 2023-06-29T04:00:00Z The body’s endocannabinoids can still bind to the receptor normally, but when THC slots in, that signaling pathway is blocked. New Drug for Cannabis Use Disorder Shows Promise in Early Trials in Humans 2023-06-21T04:00:00Z Studies in animals have shown those receptors are found in cells in regions of the brain that are particularly important for motivation and reward, pointing to one potential way semaglutide could influence cravings and desires. People on Drugs Like Ozempic Say Their ‘Food Noise’ Has Disappeared 2023-06-21T04:00:00Z There was one region in the genome for an olfactory receptor associated with how much tea someone drinks—that has a really fascinating story. Your Genes May Influence What You Like to Eat 2023-08-01T04:00:00Z For example, losing a specific pain receptor can significantly extend the life span of mice. Seeing dead fruit flies is bad for the health of fruit flies — and scientists have identified why 2023-06-14T04:00:00Z Scents that dissolve less easily in nasal mucus travel farther than more readily dissolved ones and therefore bind to more distant smell receptors. Cat Noses Contain Twisted Labyrinths That Help Them Separate Smells 2023-06-29T04:00:00Z In recent years, Costa Rica with a population of only 5 million has become one of the world’s leading receptors of asylum requests. Costa Rica-US immigration agreement aims to manage region’s flows 2023-06-13T04:00:00Z “We know that cells in the conjunctiva have ACE2 receptors on them — which are the bindings sites for the spike protein on COVID,” he said. Does COVID cause pink eye? Is there a new subvariant? Here’s what experts say 2023-06-12T04:00:00Z They tend to be these lock-and-key receptors, and if we create a different key, we might be able to alter the bindings. Your Genes May Influence What You Like to Eat 2023-08-01T04:00:00Z A group led by UC Davis geneticists found that, in addition to humans, 46 species of mammals have receptors on their cells that suggest they are vulnerable to infection with SARS-CoV-2. The coronavirus has made itself at home in animals. Why that ramps up the risk for people 2023-06-09T04:00:00Z Research into the effects of psychedelics has focused heavily on the serotonin 2A receptor in the brain, because the drugs produce hallucinations by binding to this receptor. Psychedelic-inspired drugs could relieve depression without causing hallucinations 2023-06-04T04:00:00Z Human skin has millions of receptors that sense when they are poked or pressed, squeezed or scalded. Stanford team makes electronic skin that can sense touch 2023-05-31T04:00:00Z One is chemical: a molecule arrives at the cell surface and binds to a protein receptor there, triggering some change in the receptor that initiates a signaling cascade in the cell's interior. Synthetic Morphology Lets Scientists Create New Life-Forms 2023-05-31T04:00:00Z In older adults, such changes as loss of receptor cells in the ear and eye, fogging of the eye’s lens or loss of functioning in peripheral nerves, motion sickness may either increase or decrease. Here’s What Causes Motion Sickness 2023-05-26T04:00:00Z Through examining their brain stem tissue, they found that the serotonin 2AC receptor was altered, which indicates irregularities in this system could make these infants vulnerable to death under certain conditions. Study points to brain abnormality that may explain sudden infant death syndrome 2023-05-25T04:00:00Z They injected mice with copies of a soluble version of the human ACE2 receptor. The COVID-19 virus mutated to outsmart key antibody treatments. Better ones are coming 2023-05-23T04:00:00Z Nicotine creates new receptors in the brain when it enters the body, and you quickly come to associate it with feeling good. Vaping: How do you quit e-cigarettes? 2023-05-24T04:00:00Z In healthy living skin, mechanical receptors sense information and convert it into electrical pulses that are transmitted through the nervous system to the brain. Soft ‘Electronic Skin’ Mimics Our Sense of Touch 2023-05-23T04:00:00Z In fact, through normal aging I have lost many of the receptors in my ear that sense motion. Here’s What Causes Motion Sickness 2023-05-26T04:00:00Z The drug DOI binds readily to serotonin receptors, including 2AC, and is commonly used in serotonin research. Study points to brain abnormality that may explain sudden infant death syndrome 2023-05-25T04:00:00Z As opposed to products using naloxone, such as the 4 milligram spray approved for over-the-counter sale in March, nalmefene hydrochloride acts on a user’s opioid receptors longer and is, in general, more potent. FDA approves Opvee nasal spray for opioid overdoses 2023-05-23T04:00:00Z Veozah can stop this pathway by blocking receptors in the brain’s hypothalamus, a region that keeps body temperature in check. The FDA approved a new drug for hot flashes. Here’s why it shows ‘a lot of promise’ 2023-05-22T04:00:00Z Just like heroin and morphine, fentanyl binds to the body’s opioid receptors and activates the parts of the brain associated with basic drives for safety and survival. Fentanyl has devastated King County’s homeless population, and the toll is getting worse 2023-05-21T04:00:00Z The increase in pyrogen chemicals in the blood is stimulating the receptors that reset the upper temperature limit for a febrile response. Fundamentals of Biology 2015-01-01T00:00:00Z The plasma membrane also carries receptors, which are attachment sites for specific substances that interact with the cell. Concepts of Biology 2013-04-25T00:00:00Z Arcturus isn’t the first variant that has shown an affinity for receptors in the eyes. What Is Causing So Much Pink Eye? 2023-05-12T04:00:00Z The body produces 10 times more melatonin at night than during the day, so when melatonin receptors detect this peak, they register that it’s nighttime. Should You Give Your Kid Melatonin? 2023-05-05T04:00:00Z Medications that bind to opioid receptors in the brain but don’t cause highs are one of the most effective methods to treating fentanyl dependency. Fentanyl has devastated King County’s homeless population, and the toll is getting worse 2023-05-21T04:00:00Z The blood carries the chemical that is stimulating the febrile response, but the heart rate won’t directly stimulate this receptor. Fundamentals of Biology 2015-01-01T00:00:00Z Although they are highly specific, pathogens like viruses may evolve to exploit receptors to gain entry to a cell by mimicking the specific substance that the receptor is meant to bind. Concepts of Biology 2013-04-25T00:00:00Z If a variant can more easily bind to a receptor, more virus particles can infect the cells, leading to a bigger immune response, Singh says. What Is Causing So Much Pink Eye? 2023-05-12T04:00:00Z As Young described her Ph.D. work illuminating how the poison strychnine exerts its effects at receptors for the neurotransmitter glycine in the spinal cord, Greenamyre became entranced. Twist of fate: What happens when a top Parkinson’s researcher gets the disease 2023-05-04T04:00:00Z We know which brain receptors are activated by each kind of drug and in which neurons. A New Era in Addiction Medicine: A Trailblazing Doctor’s Legacy and the Ongoing Search for a Cure 2023-05-04T04:00:00Z The blood carries the chemical that is stimulating the febrile response, but the blood pressure won’t directly stimulate this receptor. Fundamentals of Biology 2015-01-01T00:00:00Z Those cells that react weakly to the body’s own cells, but have highly specific receptors on their cell surfaces that allow them to recognize a foreign molecule, or antigen, remain. Concepts of Biology 2013-04-25T00:00:00Z Rodents, they found, tend to have the most genes for olfactory receptor proteins that pick up scents. What Makes a Mammal? 423,000 Newly Identified DNA Regions Guide Our Genes 2023-04-27T04:00:00Z He joined her lab and developed a technique for visualizing neurotransmitter receptors in the brain, which he and Young used to investigate the mechanisms of Alzheimer’s and Huntington diseases. Twist of fate: What happens when a top Parkinson’s researcher gets the disease 2023-05-04T04:00:00Z Animals have a large assortment of different olfactory receptors, each capable of binding to certain odor-causing molecules; species with more olfactory receptor genes generally have keener senses of smell. What Can You Do With a Menagerie of Mammal Genomes? 2023-04-27T04:00:00Z The hypothalamus is still the control center that responds to a stimulus from some type of receptor. Fundamentals of Biology 2015-01-01T00:00:00Z The specificity of this receptor is determined by the genetics of the individual and is present before a foreign molecule is introduced to the body or encountered. Concepts of Biology 2013-04-25T00:00:00Z These receptors are similar to those that govern humans’ circadian rhythm. How Do Birds Know When to Migrate? 2023-04-20T04:00:00Z Naloxone, which replaces opioids binding to receptors in the brain, is not habit-forming and safe to use on people who are not overdosing. Experts slam plan to sell drug overdose antidote Narcan at about $50 a kit 2023-04-20T04:00:00Z On the other hand, cetaceans — a group that includes dolphins and whales — have a notably small number of olfactory receptor genes, which makes sense given their watery habitats. What Can You Do With a Menagerie of Mammal Genomes? 2023-04-27T04:00:00Z These nerves conduct impulses from sensory receptors to the brain and spinal cord. Fundamentals of Biology 2015-01-01T00:00:00Z Figure 17.13 B cell receptors are embedded in the membranes of B cells and bind a variety of antigens through their variable regions. Concepts of Biology 2013-04-25T00:00:00Z Though scientists don’t fully understand these light-sensing receptors, one team identified certain brain cells in quails that could directly detect light, according to a study published in 2014 in Current Biology. How Do Birds Know When to Migrate? 2023-04-20T04:00:00Z These cells are dotted with the ACE2 receptors that the virus uses as an entryway. Covid May Increase the Risk of Type 2 Diabetes, Researchers Find 2023-04-18T04:00:00Z Species with more olfactory receptor genes also tended to have more olfactory turbinals, bony structures in the nasal cavity that aid olfaction. What Can You Do With a Menagerie of Mammal Genomes? 2023-04-27T04:00:00Z It contains sensory receptors which help in processing changes in the internal and external environment. Fundamentals of Biology 2015-01-01T00:00:00Z Each B cell has only one kind of antigen receptor, which makes every B cell different. Concepts of Biology 2013-04-25T00:00:00Z When enough opioid molecules bind to receptors in the brain, breathing begins to shut down. How Over-the-Counter Narcan Can Help Reverse Opioid Overdoses 2023-04-11T04:00:00Z Scientists used to think that non-nutritive sweeteners were largely inert, activating sweet receptors on our tongues and passing through our bodies without causing metabolic changes. How fake sugars sneak into foods and disrupt metabolic health Dr. Melinda Ring, an integrative medicine specialist at Northwestern Medicine, said the plant could potentially suppress dopamine receptors in the brain, which go into overdrive when we’re stressed. All About Ashwagandha, the Stress Relief Supplement of the Moment 2023-04-10T04:00:00Z Option c is correct. Thermoreceptors are located throughout the body, so it is unlikely an operation would directly damage all the receptors. Fundamentals of Biology 2015-01-01T00:00:00Z Autoimmunity can develop with time and its causes may be rooted in molecular mimicry, a situation in which one molecule is similar enough in shape to another molecule that it binds the same immune receptors. Concepts of Biology 2013-04-25T00:00:00Z And even though naloxone binds to the same receptors, it doesn’t produce the same effects—so it doesn’t cause a euphoric “high” like opioids do. How Over-the-Counter Narcan Can Help Reverse Opioid Overdoses 2023-04-11T04:00:00Z Sweet taste receptors on your tongue tell your brain that you’re eating something sweet. How fake sugars sneak into foods and disrupt metabolic health The syringe technology also holds promise for treating cancer because it can be engineered to attach to receptors on certain cancer cells. Bacterial ‘Nanosyringe’ Could Deliver Gene Therapy to Human Cells 2023-03-29T04:00:00Z The parathyroid and thyroid glands contain receptors that respond to levels of calcium in the blood. Fundamentals of Biology 2015-01-01T00:00:00Z The receptor that senses the change in the environment is part of a feedback mechanism. Concepts of Biology 2013-04-25T00:00:00Z If it turns out that someone doesn’t have opioids in their system, the procedure is still safe because naloxone only binds to mu opioid receptors. How Over-the-Counter Narcan Can Help Reverse Opioid Overdoses 2023-04-11T04:00:00Z But because these sweeteners are more potent than normal sugar with few or none of the calories, they can confuse your brain and your taste receptors. How fake sugars sneak into foods and disrupt metabolic health Loading the injection system with a toxin killed nearly all the cells bearing the receptor but did not harm other cells, illustrating its specificity. Bacterial ‘Nanosyringe’ Could Deliver Gene Therapy to Human Cells 2023-03-29T04:00:00Z Option b is correct: the endocrine system is the receptor. The endocrine system regulates many things. Fundamentals of Biology 2015-01-01T00:00:00Z The stimulus—temperature, glucose, or calcium levels—is detected by the receptor. Concepts of Biology 2013-04-25T00:00:00Z Naloxone binds to those same receptors more strongly than opioids do, so it can physically knock opioids away from the receptors and stop an overdose in its tracks. How Over-the-Counter Narcan Can Help Reverse Opioid Overdoses 2023-04-11T04:00:00Z Studies suggest that our taste receptors and willpower can be easily overwhelmed by intensely sweet flavors — even if those flavors come from fake sugar. How fake sugars sneak into foods and disrupt metabolic health This problem is "not seen in older kids or adults and remains poorly understood as cannabinoid receptors are not known to be associated with respiratory depression," Marino said. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z With 50 touch receptors for every square centimeter and about 5 million sensory cells overall, the skin is very sensitive and is the largest and one of the most complex organs in our bodies. Fundamentals of Biology 2015-01-01T00:00:00Z The bladder contains sensory nerves, stretch receptors that signal when it needs to be emptied. Concepts of Biology 2013-04-25T00:00:00Z Aromas are detected by receptors in the upper part of the nose. Sniffing body odour is tested as an anxiety therapy 2023-03-25T04:00:00Z That combination of acid and spice, dustiness and sweetness, tripped many of right receptors for me. Chipotle’s chicken al pastor is a tasty nod to the real deal 2023-03-15T04:00:00Z Our cells, including neurons, have little gates surrounding their membranes called receptors. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z This allows sodium ions to influx in, creating a receptor potential. Fundamentals of Biology 2015-01-01T00:00:00Z When neurotransmitter molecules bind to receptors located on a neuron’s dendrites, the neurotransmitter opens ion channels in the dendrite’s plasma membrane. Concepts of Biology 2013-04-25T00:00:00Z When the team manipulated receptors on the neurons to effectively turn them off, the animals didn’t cool down during anaphylaxis. Nervous system may play role in severe allergic reactions 2023-03-16T04:00:00Z It can cross the blood-brain barrier and enter neurons, and receptors for the vitamin populate many human brain regions. Vitamin D Supplements Probably Won’t Prevent Mental Illness After All 2023-03-13T04:00:00Z Similarly, if someone takes too much heroin or morphine, the drug will bind to and agonize the opioid receptors throughout the body, causing downstream effects that slow or stop breathing. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement. Fundamentals of Biology 2015-01-01T00:00:00Z Describe how hormone receptors can play a role in affecting the size of the responses of tissues to hormones. Concepts of Biology 2013-04-25T00:00:00Z Some other nasal products use triptans, which are a class of drugs aimed at serotonin receptors but are generally not recommended for people with vascular diseases. F.D.A. Approves New Nasal Spray for Migraines 2023-03-10T05:00:00Z Mice lacking receptors in these cells didn’t act sick when they got flu. Why does the flu make you feel so crummy? Neurons in throat may be to blame 2023-03-08T05:00:00Z Drugs that bind to receptors but don't activate them are called antagonists. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z Substances released by cells stimulate pain receptors in the tissue causing the sensation of pain. Fundamentals of Biology 2015-01-01T00:00:00Z A virus attaches to a specific receptor site on the host-cell membrane through attachment proteins in the capsid or proteins embedded in its envelope. Concepts of Biology 2013-04-25T00:00:00Z Humans lack the kind of cellular receptors that allow the virus to attack other species, though the World Health Organization and the Centers for Disease Control and Prevention say they are being vigilant. WH considers options to combat bird flu, including poultry vaccine 2023-03-07T05:00:00Z To narrow down where in the body this detection was happening, the team combined various genetic tools to create mouse strains with progressively smaller sets of PGE2 receptors disabled. Why does the flu make you feel so crummy? Neurons in throat may be to blame 2023-03-08T05:00:00Z That's because naloxone is a competitive receptor antagonist — the opposite of an agonist. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z The hypothalamus senses core temperature directly, and also has input from temperature receptors in the skin and modifies the sweat output, along with other thermoregulatory processes. Fundamentals of Biology 2015-01-01T00:00:00Z The attachment is specific, and typically a virus will only attach to cells of one or a few species and only certain cell types within those species with the appropriate receptors. Concepts of Biology 2013-04-25T00:00:00Z Those receptors might provide a way for the virus to directly enter the digestive system, he said. Long Covid Patients More Likely to Have Gastrointestinal Problems, Study Finds 2023-03-07T05:00:00Z Plants have evolved their own multipronged immune system, kick-started by cell receptors that recognize general pathogen features, such as a bacterial cell wall, as well as intracellular receptors for molecules secreted by specific pathogens. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z The competitive part means naloxone not only binds to these receptors, it will push out anything that's already there. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z The integumentary system encloses internal body structures and is the site of many sensory receptors. Fundamentals of Biology 2015-01-01T00:00:00Z The neurotransmitter diffuses across the synaptic cleft and binds to receptors in the post-synaptic membrane. Concepts of Biology 2013-04-25T00:00:00Z Avian influenza viruses infect birds by attaching to a receptor in their respiratory tract. Vaccine Makers Are Preparing for Bird Flu 2023-03-02T05:00:00Z But plant pathogens often evolve and evade those receptors. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z However, Marino noted that there is not yet clinical data available to support these claims, compared to the well-supported data linking cannabinoid receptor antagonists to serious side effects. Cannabis can cause overdoses. Can these drugs reverse it? 2023-03-27T04:00:00Z The control center or integration center receives and processes information from the receptor. Fundamentals of Biology 2015-01-01T00:00:00Z These receptor molecules are chemically regulated ion channels and will open, allowing sodium to enter the cell. Concepts of Biology 2013-04-25T00:00:00Z While human cases of H5N1 are rare — humans don’t have the type of receptors that make other species more vulnerable to infection — the public health community is worried about mutations that could spark another pandemic. Bird flu situation is ‘under control’ after rural scare, say Cambodian officials 2023-02-27T05:00:00Z One approach is to edit the gene for a plant immune receptor, altering the protein’s shape to recognize a particular pathogenic molecule. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z Human cases of bird flu are rare, as humans do not have the receptors in their throats, noses, and upper respiratory tracts that are susceptible to the current virus strain. H5N1: Cambodian girl dies in rare bird flu case 2023-02-24T05:00:00Z An olfactory receptors neuron sends an impulse via Cranial nerve I the olfactory nerve. Fundamentals of Biology 2015-01-01T00:00:00Z Hormones circulate throughout the body and stimulate a response in cells that have receptors able to bind with them. Concepts of Biology 2013-04-25T00:00:00Z What has not changed, even in mink, is that the virus still prefers to bind to avian-type receptors to enter and infect cells. Analysis: Why public health officials are not panicked about bird flu 2023-02-23T05:00:00Z This requires specific knowledge of both the receptor and its target on the pathogen. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z Avian influenza binds best to a receptor that’s very common in birds, but significantly less so in humans, Butcher said. What’s the risk of bird flu outbreak crossing to humans? 2023-02-22T05:00:00Z Each olfactory receptor neuron in the nose expresses only one functional odor receptor. Fundamentals of Biology 2015-01-01T00:00:00Z Additionally, the number of receptors available to respond to a hormone can change over time, resulting in increased or decreased cell sensitivity. Concepts of Biology 2013-04-25T00:00:00Z Mink have both avian and human-type receptors, but avian receptors are scarce in humans and located deep in the lungs. Analysis: Why public health officials are not panicked about bird flu 2023-02-23T05:00:00Z It took several tries and tweaks to create plants that did not mount autoimmune responses because of the modified receptors, which would have stunted growth and impaired fertility. Alpaca-derived antibodies could protect plants from disease 2023-03-01T05:00:00Z For it to spread efficiently between humans, it would have to get better at attaching to receptors that are more common in our noses and throats, which hasn’t happened so far, he said. What’s the risk of bird flu outbreak crossing to humans? 2023-02-22T05:00:00Z Odor receptor nerve cells may function like a key-lock system: if the odor molecules can fit into the lock the nerve cell will respond. Fundamentals of Biology 2015-01-01T00:00:00Z All viruses use some sort of glycoprotein to attach to their host cells at molecules on the cell called viral receptors. Concepts of Biology 2013-04-25T00:00:00Z Human flu viruses typically bind to receptors found in the upper respiratory tract. Analysis: Why public health officials are not panicked about bird flu 2023-02-23T05:00:00Z This research emphasizes that it's not just the molecule that matters, but where the receptor is located. New research illuminates how the human brain creates its own psychedelic drugs 2023-02-20T05:00:00Z Swine have receptors that overlap with both birds and humans, and if a pig were infected with both, the viruses could swap genes and gain the ability to infect the other species, he said. What’s the risk of bird flu outbreak crossing to humans? 2023-02-22T05:00:00Z According to shape theory, each receptor detects a feature of the odor molecule. Fundamentals of Biology 2015-01-01T00:00:00Z Each receptor is structured to bind with a specific substance. Concepts of Biology 2013-04-25T00:00:00Z "The saving grace for humans right now is it seems that it's really, really difficult for this virus to switch receptor preference," Webby said. Analysis: Why public health officials are not panicked about bird flu 2023-02-23T05:00:00Z The considerable hype surrounding ketamine stems in part from the drug’s ability to affect brain receptors that traditional antidepressants do not target. A Fraught New Frontier in Telehealth: Ketamine 2023-02-20T05:00:00Z Avian flu viruses are adapted to bind to birds' receptor cells. As climate change disrupts ecosystems, a new outbreak of bird flu spreads to mammals 2023-02-16T05:00:00Z An alternative theory, the vibration theory proposed by Luca Turin2, posits that odor receptors detect the frequencies of vibrations of odor molecules in the infrared range by electron tunneling. Fundamentals of Biology 2015-01-01T00:00:00Z For example, surface receptors of the membrane create changes in the interior, such as changes in enzymes of metabolic pathways. Concepts of Biology 2013-04-25T00:00:00Z Doing so revealed a thermal receptor called BRTNaC1, an ion channel that pumps electrically charged atoms between cells throughout the centipede’s antennae. These centipedes ‘see’ sunlight, even without eyes 2023-02-12T05:00:00Z With their vasopressin receptor levels boosted in this brain region, these normally solitary and promiscuous voles gained a new propensity to cuddle with a mate. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z With hepatitis treatments in mind, they had previously acquired a drug based on lambda interferons, a lesser-known type of interferon whose receptors are largely restricted to specific areas, like the respiratory tract. Why the Odds Are Stacked Against a Promising New Covid Drug 2023-02-08T05:00:00Z An olfactory receptor neuron, also called an olfactory sensory neuron, is the primary transduction cell in the olfactory system. Fundamentals of Biology 2015-01-01T00:00:00Z T cells with cell-surface receptors that bind a specific antigen will bind to that APC. Concepts of Biology 2013-04-25T00:00:00Z The BRTNaC1 receptor is triggered by temperatures between 33°C and 48° C. The researchers concluded that when light warms the centipedes’ antennae, it sparks the activation of BRTNaC1. These centipedes ‘see’ sunlight, even without eyes 2023-02-12T05:00:00Z One idea is that during development other genes or neural pathways naturally compensate for the lack of oxytocin receptors. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z And it meant that the side effects would theoretically be less intense than those from the more commonly used class of interferons, whose receptors are throughout the body. Why the Odds Are Stacked Against a Promising New Covid Drug 2023-02-08T05:00:00Z Humans have about 40 million olfactory receptor neurons. Fundamentals of Biology 2015-01-01T00:00:00Z Hormones cause cellular changes by binding to receptors on or in target cells. Concepts of Biology 2013-04-25T00:00:00Z For reasons that are not yet clear, increased testosterone dampened the activity of the BRTNaC1 receptor and resulted in the centipedes spending more time in the light. These centipedes ‘see’ sunlight, even without eyes 2023-02-12T05:00:00Z We already know that there are many other genes that influence pair-bonding, not only oxytocin, vasopressin and their receptors. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z It can’t block interferon receptors, though, so injecting interferons into the body can sound the alarm, readying cells to fight the virus. New COVID Antiviral Cuts Hospitalizations in Half 2023-02-08T05:00:00Z In vertebrates, olfactory receptor neurons reside on the olfactory epithelium in the nasal cavity. Fundamentals of Biology 2015-01-01T00:00:00Z The molecular basis for this specificity is that a particular surface molecule, known as the viral receptor, must be found on the host cell surface for the virus to attach. Concepts of Biology 2013-04-25T00:00:00Z She thought that large amounts of the medicine could be breaking down estrogen receptors, a protein that is crucial to many tumors’ ability to grow and metastasize. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z The findings supported the idea that differences in the distribution of hormone receptors could account for the different behaviors of promiscuous and monogamous voles. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z This happens because the receptor they bind to is found in numerous tissues, as well as on immune cells, so boosting type I interferons can put the immune response into overdrive. New COVID Antiviral Cuts Hospitalizations in Half 2023-02-08T05:00:00Z Many tiny hair-like cilia protrude from the olfactory receptor cell’s dendrite and into the mucus covering the surface of the olfactory epithelium. Fundamentals of Biology 2015-01-01T00:00:00Z Once activated, the TC creates a large clone of cells with one specific set of cell-surface receptors, as in the case with proliferation of activated B cells. Concepts of Biology 2013-04-25T00:00:00Z In healthy cells, these receptors bind to estrogen and cause normal changes in breast tissue. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z Hormones influence the functions of the body’s cells by binding to large proteins known as receptors, whose shape and electrical charge interact with one particular hormone. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z Naloxone works by attaching itself to the same receptors in the brain as opioids, blocking or reversing their effects. L.A. students will be able to carry Narcan in schools under updated policy 2023-02-01T05:00:00Z These cilia contain olfactory receptors, a type of G protein-coupled receptor. Fundamentals of Biology 2015-01-01T00:00:00Z In patients with myasthenia gravis, an autoimmune disease, muscle-cell receptors that induce contraction in response to acetylcholine are targeted by antibodies. Concepts of Biology 2013-04-25T00:00:00Z But in the majority of women with metastatic breast cancer, the estrogen receptor within the tumors eventually mutate, allowing them to progress despite the lack of estrogen. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z When a hormone binds to its receptor protein, it causes a change in the receptor’s shape that triggers changes within the cell. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z Hot flashes originate in the hypothalamus, an area of the brain rich in estrogen receptors that is both crucial in the reproductive cycle and also functions as a thermostat. Women Have Been Misled About Menopause 2023-02-01T05:00:00Z Each olfactory receptor cell contains only one type of olfactory receptor, but many separate olfactory receptor cells contain the same type of olfactory receptor. Fundamentals of Biology 2015-01-01T00:00:00Z Thanks to an abundance of olfactory receptors on their antennae, the insects have an incredible sense of smell—and they can use it to detect tumors. Ants Can Sniff Out Cancer 2023-01-24T05:00:00Z If a medicine could kill the estrogen receptors in the tumors altogether, McDonnell’s lab thought, it could slow the tumor’s progression despite mutations in the receptor. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z Because oxytocin and vasopressin are present in many species but promote bonding only in some species, it seemed plausible that there might be species differences in the distribution of hormone receptors. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z "All of a sudden, it binds to the host receptor better than most variants that we know so far." Bivalent boosters protect against the super-infectious new variant XBB.1.5, new data finds 2023-01-27T05:00:00Z The axons of olfactory receptor cells of the same type converge to form glomeruli in the olfactory bulb. Fundamentals of Biology 2015-01-01T00:00:00Z Doctors hypothesize the virus can infect the heart cells by unlocking key cell receptors, creating an invasion of the organ. COVID-19 increases risk of heart attack, says U.K. study 2023-01-27T05:00:00Z They tried again in 2013, when they discovered that an osteoporosis medication could similarly target and kill estrogen receptors. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z But to understand exactly how hormone receptors shape bonding, researchers needed to manipulate the genes that encode the receptors. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z Research teams have for many years explored the idea of decoy receptors for HIV and a few others viruses but made little clinical headway for various reasons. Protein decoys for viruses may battle COVID-19 and more 2023-01-26T05:00:00Z Olfactory receptors can bind to a variety of odor molecules. Fundamentals of Biology 2015-01-01T00:00:00Z In active cases, the virus has the ability to bind to the ACE2 receptor on cells in the lungs and heart and cause myocarditis. COVID-19 increases risk of heart attack, says U.K. study 2023-01-27T05:00:00Z The whole process — from when McDonnell’s lab first thought to target estrogen receptors to January, when the FDA approved the medication — took nearly three decades. After 30 years of research, pill developed for breast cancer approved for use 2023-02-08T05:00:00Z Likewise, when a human subject holds her partner’s hand, it activates her nucleus accumbens—one of the brain regions that in prairie voles has receptors for oxytocin and vasopressin. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z The receptor protein normally helps regulate blood pressure and other metabolic processes, but it can also contribute to conditions such as lung failure. Protein decoys for viruses may battle COVID-19 and more 2023-01-26T05:00:00Z Individual olfactory receptor neurons are replaced approximately every 40 days by neural stem cells residing in the olfactory epithelium. Fundamentals of Biology 2015-01-01T00:00:00Z Cannabinoid receptors have a lot more functions than getting one stoned, of course. Why does cannabis keep some people skinny? Experts explain how weed and metabolism are connected 2023-01-26T05:00:00Z Because the receptors the virus binds to in the upper airways of birds are less common in mammalian upper airways, H5N1 largely spares mammals. ‘Incredibly concerning’: Bird flu outbreak at Spanish mink farm triggers pandemic fears 2023-01-24T05:00:00Z The work showed that the abundance of vasopressin receptors in the brain’s reward circuits explained at least some of the behavioral differences between monogamous and promiscuous voles. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z That means it likes to interact with a lot of different receptors in the body; it sometimes likened to a shotgun blast that doesn't discriminate where it hits. What happens to your body after you quit drinking, according to experts 2023-01-12T05:00:00Z Stretching and compressing the tip links may open an ion channel and produce the receptor potential in the hair cell. Fundamentals of Biology 2015-01-01T00:00:00Z But scientists noticed that participants in clinical trials also lost weight, owing to GLP-1’s effect on receptors in the brain that govern appetite and those in the gut that slow digestion. ‘Breakthrough’ Obesity Drugs Are Effective but Raise Questions 2023-01-10T05:00:00Z E627K, another worrisome mutation in the polymerase gene, has not emerged, however, and the gene for hemagglutinin—a protein on the viral surface that latches on to the host receptor—has not changed, Peacock says. ‘Incredibly concerning’: Bird flu outbreak at Spanish mink farm triggers pandemic fears 2023-01-24T05:00:00Z But shockingly, prairie voles that lacked the oxytocin receptor altogether actually formed preferences for mates as readily as their genetically unmanipulated siblings. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z With the company Kirin Holdings, Miyashita’s team developed specialized chopsticks: a weak electrical current runs through this novel cutlery, shifting the sodium ions in a mouthful of food to excite the tongue’s salt receptors. Flavor-Enhancing Spoons and Chopsticks Could Make Food Taste Better 2023-01-09T05:00:00Z T-cells contain antigen receptors on their surface that combine with antigenic determinants on pathogens. Fundamentals of Biology 2015-01-01T00:00:00Z In fact, scientists have long thought that GIP actually encourages obesity: mice with dysfunctional GIP receptors are resistant to obesity. ‘Breakthrough’ Obesity Drugs Are Effective but Raise Questions 2023-01-10T05:00:00Z These two mutations maintain the high level of immune escape of XBB, while also adding more infectivity advantage, giving the virus better ability to attach itself to the receptors that get it into our cells. Opinion | The coronavirus is speaking. It’s saying it’s not done with us. 2023-01-08T05:00:00Z The discovery that the oxytocin receptor is not strictly necessary for prairie vole bonding demonstrates that however important the genes encoding oxytocin, vasopressin and their receptors may be, they are not the whole story. Monogamous Prairie Voles Reveal the Neurobiology of Love 2023-02-13T05:00:00Z Ray said this one attaches more tightly than its competitors to a receptor that allows viruses to enter a cell. As COVID surges in China, U.S. begins testing more travelers 2023-01-05T05:00:00Z The antigen receptors are polypeptide chains that contain variable and constant regions. Fundamentals of Biology 2015-01-01T00:00:00Z Therefore, to induce weight loss, researchers thought the receptor should be switched off. ‘Breakthrough’ Obesity Drugs Are Effective but Raise Questions 2023-01-10T05:00:00Z Both parents are particularly good at binding to the ACE2 receptor — the part of the cell the virus’ spike protein attacks to initiate an infection — and their descendants seem to have inherited that talent. The XBB.1.5 variant is taking over on the East Coast. Will it happen in California too? 2023-01-05T05:00:00Z The spike protein is the perfect shape to slide into ACE2 receptors, which line many of the cells in our body. Why the new COVID variant XBB.1.5 is taking over the U.S. so quickly 2023-01-04T05:00:00Z The researchers intend to apply the technology to a motor with a biological function, such as binding to certain cell receptors. Lab-Made Motors Could Move and Glow in Cells 2022-12-30T05:00:00Z Specialized cells act as receptors for certain chemical compounds. Fundamentals of Biology 2015-01-01T00:00:00Z After initial studies demonstrated that activating both the GIP and GLP-1 receptors caused weight loss, pharmaceutical companies created their own molecules achieving the same results, thus confirming that the method worked. ‘Breakthrough’ Obesity Drugs Are Effective but Raise Questions 2023-01-10T05:00:00Z "Identifying those receptors is progress in the fight to cure parosmia because it means scientists can look at how they work - or don't - and whether they can be helped to work better," he says. Since Covid, my Christmas dinner tastes like mould 2022-12-21T05:00:00Z ACE2 receptors play many important roles, such as regulating blood pressure. Why the new COVID variant XBB.1.5 is taking over the U.S. so quickly 2023-01-04T05:00:00Z This is in part, she says, because oxytocin receptor sites, the uterine cells that detect oxytocin and cause contractions, are low in number during early pregnancy and increase approximately twelvefold by 37 to 41 weeks. Is nursing while pregnant risky? 2022-12-12T05:00:00Z As these compounds react with the receptors, an impulse is sent to the brain and is registered as a certain taste or smell. Fundamentals of Biology 2015-01-01T00:00:00Z A viral surface protein used in the vaccines changes its shape after it docks onto a cellular receptor and the virus fuses with the cell, establishing an infection. Science’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew 2022-12-14T05:00:00Z If you have a mutation in that particular receptor, then the virus can’t get into your cells and can’t infect you. Who Are the ‘Never-Coviders’? 2022-12-14T05:00:00Z They still seem to bind to serotonin receptors in the brain, however, meaning they may still produce some therapeutic effect. Psychedelic startups are betting on synthetic versions of "magic" mushrooms as the future 2022-12-13T05:00:00Z “Oxytocin receptors are not well-developed in the uterus throughout pregnancy, so that perhaps that is the reason that people can have mild contractions and not go into preterm labor,” she says. Is nursing while pregnant risky? 2022-12-12T05:00:00Z Gustation and olfaction are chemical senses because the receptors they contain are sensitive to the molecules in the food we eat, along with the air we breathe. Fundamentals of Biology 2015-01-01T00:00:00Z When the coronavirus binds to a specific type of receptor on the surface of a cell, it drives its spike protein in like a switchblade and initiates an infection. Experimental decoy drug tricks coronavirus, then destroys it 2022-12-07T05:00:00Z The disease, also known as anti-NMDA receptor encephalitis, triggers odd behavior that mimics psychosis. This teenager would sleep for alarming 20-hour stretches 2022-11-19T05:00:00Z For instance, we might first see whether the virus can engage a receptor on human cells to gain entry. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z The medication binds to the same receptors in the brain as opioids, reversing or blocking their effects. California programs are waiting weeks for free Narcan to prevent overdose deaths 2022-11-14T05:00:00Z When semaglutide agonizes these receptors, it tells the body to make more insulin. Diabetes drug semaglutide is surging in popularity. Is it safe? 2022-11-12T05:00:00Z The drug is designed to mimic that receptor, working like an assassin in an attractive disguise. Experimental decoy drug tricks coronavirus, then destroys it 2022-12-07T05:00:00Z Such proteins can be found across many blood and lymph cancers, which means there is no need to design new T-cell receptors for each person with cancer. In First, Scientists Use CRISPR for Personalized Cancer Treatment 2022-11-11T05:00:00Z One way we can do that is to take a cell line from the animal host, knock out the receptor the virus uses and replace it with the human version. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z They use proteins - called receptors - to effectively sniff out signs of infection or deviant cells that have become cancerous. 'Leap forward' in tailored cancer medicine 2022-11-10T05:00:00Z Luckily, the sun steps in to help us by sending signals to specialized receptors in our eyes. Why daylight saving time is worse for your body than standard time But while the virus has changed, the homing beacon it looks for in human cells — the ACE2 receptor — has not. Experimental decoy drug tricks coronavirus, then destroys it 2022-12-07T05:00:00Z Sunlight gently pulls us back into the 24-hour cycle of the sun clock by sending signals to specialized receptors in our eyes. Daylight savings time Q&A: What to know about the time change 2022-11-04T04:00:00Z If the virus can still replicate at normal levels, that means it can use the human receptor just fine. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z Transforming T-cells into a form that can hunt cancer requires considerable genetic manipulation to both remove the genetic instructions for building their old receptors, and give them the instructions for the new ones. 'Leap forward' in tailored cancer medicine 2022-11-10T05:00:00Z They can locate prey by detecting electrical fields using receptors on their duck bills. Dammed Rivers Spell Peril, and Inbreeding, for Platypuses 2022-11-04T04:00:00Z He called the use of decoys to block viruses “fairly new” and said the researchers’ focus on the ACE2 receptor makes it a “promising” way to block or limit a runaway infection. Experimental decoy drug tricks coronavirus, then destroys it 2022-12-07T05:00:00Z The transient receptor potential channels on cells in our mouth and throat react quickly to mustard and reverse the nerve misfiring that leads to muscle contractions. Athlete’s foot bleach treatment is controversial 2022-11-02T04:00:00Z And if we see no replication, that means that the virus can’t use the receptor yet. How Viruses Hop from Wild Animals to Humans 2022-11-21T05:00:00Z For example, most people have three types of cones—light receptors in the eye that are optimized to detect different wavelengths or colors of light. Color Is in the Eye, and Brain, of the Beholder 2022-11-01T04:00:00Z Pasquesi adds that it’s technically impressive the authors managed to figure out which receptor these retroviruses were using to enter cells. Ancient virus may be protecting the human placenta 2022-10-27T04:00:00Z But Cardozo warned that since ACE2 receptors appear in many different tissues and play a variety of signaling roles, researchers will need to proceed with care. Experimental decoy drug tricks coronavirus, then destroys it 2022-12-07T05:00:00Z The average human nose contains about 350 types of olfactory receptors, which can bind to a potentially enormous number of airborne molecules. AI Predicts What Chemicals Will Smell like to a Human 2022-10-27T04:00:00Z Because it lacks three types of receptor found in other forms of breast cancer, drugs which work for them have no impact on TNBC. Aggressive breast cancer hits black women harder 2022-10-25T04:00:00Z Excessive estrogen can overly stimulate hormone receptors, causing cancer cells to multiply and spread. Uterine Cancer Cases Are Rising. Here’s What to Know. 2022-10-25T04:00:00Z One reason for this, the authors suggested, is "cannabinoid receptors may become saturated with THC at higher levels, beyond which there is a diminishing effect of additional THC." Marijuana is more potent than it used to be. But is it dangerous? 2022-10-21T04:00:00Z Lasers on one end fire at rapid rates down thin glass fibres to receptors at the other end of the cable. Shetland telecoms cable damage 'caused by fishing vessels' 2022-10-20T04:00:00Z These receptors then initiate neuronal signals that the brain later interprets a whiff of coffee, gasoline or perfume. AI Predicts What Chemicals Will Smell like to a Human 2022-10-27T04:00:00Z But something unexpected happened when his lab added spike from a bat coronavirus called SHC014: The chimeric virus sickened mice carrying a human lung cell receptor, Baric’s team reported in 2015 in Nature Medicine. U.S. weighs crackdown on experiments that could make viruses more dangerous 2022-10-18T04:00:00Z |
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