| 单词 | proteome |
| 例句 | Unlike a genome, a proteome is dynamic and under constant flux, which makes it more complicated and more useful than the knowledge of genomes alone. Concepts of Biology 2013-04-25T00:00:00Z Thus, the genome is constant, but the proteome varies and is dynamic within an organism. Biology for AP Courses 2022-06-09T00:00:00Z Just as the cell’s genome describes its full complement of DNA, a cell’s proteome is its full complement of proteins. Anatomy and Physiology 2013-06-19T00:00:00Z Its end goal is providing a “proteome,” or a complete profile showing the amounts of each protein in blood samples, or tissue samples from different organs in the human body. Seattle biotech startup aims for ‘new paradigm’ in medicine by parsing proteins 2021-08-01T04:00:00Z In fact, just 17% of the proteome is covered by a structure confirmed experimentally. AI breakthrough will 'transform' biology 2021-07-22T04:00:00Z Most significantly, the release includes predictions for 98 percent of all human proteins, around 20,000 different structures, which are collectively known as the human proteome. DeepMind creates ‘transformative’ map of human proteins drawn by artificial intelligence 2021-07-22T04:00:00Z Although the genome provides a blueprint, the final architecture depends on several factors that can change the progression of events that generate the proteome. Biology for AP Courses 2022-06-09T00:00:00Z The composition of the proteome depends on the kind of tissue being examined, but will often include various forms of collagen. Move over, DNA: ancient proteins are starting to reveal humanity’s history 2019-06-25T04:00:00Z Unlike the genome, which stays largely the same, an organism’s proteome changes all the time. Do Proteins Hold the Key to the Past? 2018-11-19T05:00:00Z Collectively, biologists refer to this full complement as the "proteome". AI breakthrough will 'transform' biology 2021-07-22T04:00:00Z Coordination of bacterial proteome with metabolism by cyclic AMP signalling. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z Unlike a genome, a proteome is dynamic and in constant flux, which makes it both more complicated and more useful than the knowledge of genomes alone. Biology for AP Courses 2022-06-09T00:00:00Z He envisions a website where scientists could upload a genome, or what’s called the proteome — the amino acids chains that make up a protein — and exchange it for a music file. Studying the Building Blocks of Life in Stereo Sound 2016-10-21T04:00:00Z The proteome of a single human cell, which might contain billions of proteins, is sometimes compared to an atlas. Do Proteins Hold the Key to the Past? 2018-11-19T05:00:00Z “There is no such thing as a human proteome in one person, let alone in many people,” says Küster. Proteomics: High-protein research : Nature : Nature Publishing Group 2015-11-03T05:00:00Z Pavlov, M. Y. & Ehrenberg, M. Optimal control of gene expression for fast proteome adaptation to environmental change. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z The genome is constant but the proteome is dynamic as different tissues possess the same genes but express different genes, thereby complementing genomics. Biology for AP Courses 2022-06-09T00:00:00Z Only 1,058 spliced genes have alternative first exons that alter protein-encoding capacity and increase the complexity of the predicted proteome. Diversity and dynamics of the Drosophila transcriptome : Nature : Nature Publishing Group 2014-03-15T04:00:00Z Computational biology may lead to breakthroughs in our ability to understand genetics, epi-genetics, the proteome and the importance of flora in our digestive systems. Vinton G. Cerf: The Value of "Investment by the U.S. Government" Cannot Be Overstated 2014-07-22T04:00:00Z Whatever the technical approach, mapping the human proteome is no easy task. Proteomics: High-protein research : Nature : Nature Publishing Group 2015-11-03T05:00:00Z Overflow metabolism in Escherichia coli results from efficient proteome allocation. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z A proteome is the entire set of proteins produced by a cell type. Biology for AP Courses 2022-06-09T00:00:00Z Pandey said the human proteome is so vast and complicated it may never be completed. Researchers Identify New Genetic Building Blocks 2014-05-28T04:00:00Z Molecular chaperones are found in all cells and are essential for maintaining a functional proteome. [Perspective] Trigger Factor Flexibility 2014-05-08T18:25:52.499Z We examined the clinical features and the plasma metabolome and proteome of patients with and without community-acquired sepsis, upon their arrival at hospital emergency departments and 24 hours later. [Research Articles] An Integrated Clinico-Metabolomic Model Improves Prediction of Death in Sepsis 2013-07-24T19:25:07.917Z This table shows proteome sectors, see Supplementary Information document for full description. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z When you tie genome sequencing to proteome sequencing, it adds billions of data points across millions of patients. Blood Work 2013-05-09T11:00:36Z “Had you only followed transcriptome or proteome, you would have only got part of the picture.” Big biology: The ’omes puzzle 2013-02-27T18:20:44.453Z In , alternative splicing may serve as an additional mechanism for increasing proteome complexity and compensating for the loss of organellar genes. Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs 2012-12-05T18:51:06.810Z He eventually found an outlet for his frustration through proteomics — the study of the body's vast ecosystem of proteins known as the proteome. Megadata: The odd couple 2012-11-23T15:20:51.020Z Here we develop a top-down approach, expanding the recently established coarse-grained proteome allocation models15,18,19,20 from steady-state growth into the kinetic regime. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z The proteome of the shell was obtained by mass spectrometry. The oyster genome reveals stress adaptation and complexity of shell formation 2012-10-03T18:22:26.103Z For example, he envisions using an array of the sensors to identify every protein in human blood serum, the so-called plasma proteome. Tiny Mechanical Scale Weighs Molecules One at a Time 2012-08-29T18:24:58Z For analyses of specific gene families, the 36,542 protein sequences were inserted in the plant proteome clustering of the GreenPhyl database. The banana (Musa acuminata) genome and the evolution of monocotyledonous plants 2012-08-08T17:21:46.387Z Together, the pair set about creating a computer model that could contrast a healthy proteome with those of identified cancer patients to find biomarkers for the disease. Megadata: The odd couple 2012-11-23T15:20:51.020Z Although characterized by significant oxidative stress, the naked mole rat proteome does not show age-related susceptibility to oxidative damage or increased ubiquitination. Genome sequencing reveals insights into physiology and longevity of the naked mole rat 2011-11-15T17:21:47.017Z Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome reveals stress adaptation and complexity of shell formation 2012-10-03T18:22:26.103Z Roukes's technique measures only mass and doesn’t chemically identify any molecule, McLean says, so it may not be helpful in sorting out the mishmash in the plasma proteome. Tiny Mechanical Scale Weighs Molecules One at a Time 2012-08-29T18:24:58Z This combination has convinced many scientists that the time has come to pull the proteome out of the witch's cauldron and into the daylight. Megadata: The odd couple 2012-11-23T15:20:51.020Z But the proteome is far more varied and complex than the genome, so analysing it is a daunting proposition. Megadata: The odd couple 2012-11-23T15:20:51.020Z Agus wanted to create a whole-body picture of the proteome at any given time using just a sample of urine or blood. Megadata: The odd couple 2012-11-23T15:20:51.020Z Harnessing the proteome would be a monumental challenge, however, and Hillis knew that. Megadata: The odd couple 2012-11-23T15:20:51.020Z If cancer proteins can be separated out from the noise of the human proteome, doctors could tailor therapies to an individual's chemistry and target therapies for each individual cancer. Megadata: The odd couple 2012-11-23T15:20:51.020Z With a full picture of the proteome, drugs that were previously considered failures — those that cured only a small percentage of patients — could be used in a suite of treatments tailored to individual chemistry. Megadata: The odd couple 2012-11-23T15:20:51.020Z It is hard to overstate how much more complicated the proteome is than the genome. Megadata: The odd couple 2012-11-23T15:20:51.020Z Other scientists have previously tried to find patterns in the human proteome but with little success. Megadata: The odd couple 2012-11-23T15:20:51.020Z The NCI has launched several efforts to catalogue the proteome, and the Obama administration is calling for a 'proteome project' analogous to the Human Genome Project, but progress has been disappointingly slow. Megadata: The odd couple 2012-11-23T15:20:51.020Z |
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